Flow Cytometry: The Flow Cytometry facility at SLS offers researchers with state of the art technologies in the field of Flow Cytometry. It offers training to academic, industry and commercial units in basic and advanced aspects of flow cytometry techniques and associated data analysis. The facility is best utilized for the isolation and study of specific cell types, measuring absolute number of cells, percentage of live cells and other characteristics of cells such as immunophenotyping, stem cell enumeration, cell cycle analysis, ploidy determination, apoptosis and necrosis, mitochondrial aspects including many other properties of the cells. In addition to this, center also provides solutions to tailored approaches to address specific scientific investigations. The center is equipped with instruments from Becton Dickinson and Partek.
Genomics: The genomics facility at SLS offers researchers with state of the art technologies in the field of genomics and high throughput diagnostics. The facility is available to academia, industry and commercial units both within India and abroad. The facility can be utilized for genome wide studies involving DNA sequencing, genotyping and gene expression studies. The center is equipped with Digital and real time PCR, Sanger sequencer, Next generation sequencing (Ion Platforms) and Microarray Scanner (Agilent Technologies) to undertake advanced genomic, epigenomic and gene expression studies.
Microscopy and Imaging: The microscopy facility at SLS offers researchers with state of the art technologies in the field of wide field and confocal microscopy. The facility is available 24X7 for students, technicians, postdocs, faculty and industry users. It offers fixed and live cells imaging of samples allowing 2D and 3D image rendering, ROI scanning, time lapse imaging, quantification, co-localization and FRAPS and FRETS applications. The center is equipped Leica DMi8-SP8 confocal microscopy system for advanced imaging and image analysis.
Proteomics and Metabolomics: Mass spectrometry facility at SLS provides state of art research solutions in the field of metabolomics, proteomics and drug synthesis and chemistry. The facility is open to researchers in both academia and industry. The range of services we offer includes technical advice on designing experiment, sample preparation, development of new methods and data interpretation. We have undertaken several projects related to pharmacometabolomics of drug response in diseases, quality check of synthesized drugs, drug metabolism, studying shift in metabolic pathways during physiological and pathological response in human cell culture models, identification of proteins, screening secondary metabolites in plant and microbial systems.
Bioinformatics: SOLS provides state of art research solutions in the field of Bioinformatics. With the help of commercial, publically available software’s and in house developed pipelines, we provide high end bioinformatic support to researchers in the area of advanced genomics, epigenomics and proteomics data. The bioinformatic core also provides consultation and training on analyzing high throughput genome wide data , database development and management.