Department of Clinical Embryology, Kasturba Medical College, Manipal

  • India

Research Output

  • 1321 Citations
  • 22 h-Index
  • 103 Article
  • 2 Chapter
  • 2 Review article
  • 1 Comment/debate
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Article
4 Citations (Scopus)

Laser-assisted hatching of cleavage-stage embryos impairs developmental potential and increases DNA damage in blastocysts

Honguntikar, S. D., Uppangala, S., Salian, S. R., Kalthur, G., Kumar, P. & Adiga, S. K., 2014, In : Lasers in Medical Science. 30, 1, p. 95-101 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Laser assisted zona hatching does not lead to immediate impairment in human embryo quality and metabolism

Uppangala, S., D’Souza, F., Pudakalakatti, S., Atreya, H. S., Raval, K., Kalthur, G. & Adiga, S. K., 01-11-2016, In : Systems Biology in Reproductive Medicine. 62, 6, p. 396-403 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2 Citations (Scopus)

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

Nair, R., Singh, V. J., Salian, S. R., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Kalthur, G. & Adiga, S. K., 2014, In : Toxicology and Applied Pharmacology. 279, 3, p. 338-350 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
6 Citations (Scopus)

Nano-transfersomal formulations for transdermal delivery of asenapine maleate: in vitro and in vivo performance evaluations

Shreya, A. B., Managuli, R. S., Menon, J., Kondapalli, L., Hegde, A. R., Avadhani, K., Shetty, P. K., Amirthalingam, M., Kalthur, G. & Mutalik, S., 02-07-2016, In : Journal of Liposome Research. 26, 3, p. 221-232 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Naringin nano-ethosomal novel sunscreen creams: Development and performance evaluation

Gollavilli, H., Hegde, A. R., Managuli, R. S., Bhaskar, K. V., Dengale, S. J., Reddy, M. S., Kalthur, G. & Mutalik, S., 09-2020, In : Colloids and Surfaces B: Biointerfaces. 193, 111122.

Research output: Contribution to journalArticle

NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: A new biomarker for assessment of embryo implantation potential

Pudakalakatti, S. M., Uppangala, S., D'Souza, F., Kalthur, G., Kumar, P., Adiga, S. K. & Atreya, H. S., 01-2013, In : NMR in Biomedicine. 26, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
10 Citations (Scopus)
3 Citations (Scopus)

Oocytes recovered after ovarian tissue slow freezing have impaired H2AX phosphorylation and functional competence

Sudhakaran, S., Uppangala, S., Salian, S. R., Honguntikar, S. D., Nair, R., Kalthur, G. & Adiga, S. K., 2015, In : Reproduction, Fertility and Development. 27, 8, p. 1242-1248 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ovarian tissue vitrification is more efficient than slow freezing in protecting oocyte and granulosa cell DNA integrity

Mathias, F. J., D'souza, F., Uppangala, S., Salian, S. R., Kalthur, G. & Adiga, S. K., 01-12-2014, In : Systems Biology in Reproductive Medicine. 60, 6, p. 317-322 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

p21 provides stage specific DNA damage control to preimplantation embryos

Adiga, S. K., Toyoshima, M., Shiraishi, K., Shimura, T., Takeda, J., Taga, M., Nagai, H., Kumar, P. & Niwa, O., 13-09-2007, In : Oncogene. 26, 42, p. 6141-6149 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Paternal DNA damage suppresses in vitro proliferation of mouse inner cell mass

Adiga, S. K., Toyoshima, M., Shimura, T., Takeda, J., Uematsu, N., Kumar, P. & Niwa, O., 2009, In : Journal of the Turkish German Gynecology Association. 10, 1, p. 6-9 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Phase modulated 2D HSQC-TOCSY for unambiguous assignment of overlapping spin systems

Singh, A., Dubey, A., Adiga, S. K. & Atreya, H. S., 01-01-2018, In : Journal of Magnetic Resonance. 286, p. 10-16 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
4 Citations (Scopus)

Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells

Khaw, A. K., Sameni, S., Venkatesan, S., Kalthur, G. & Hande, M. P., 01-11-2015, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 793, p. 86-95 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men

Varshini, J., Srinag, B. S., Kalthur, G., Krishnamurthy, H., Kumar, P., Rao, S. B. S. & Adiga, S. K., 05-2012, In : Andrologia. 44, SUPPL.1, p. 642-649 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

PPAR-gamma: A dagger in endometriosis

Amberkar, M. V., Meena Kumari, K., Mor, V., Semwal, A. & Adiga, S., 2010, In : Australasian Medical Journal. 3, 12, p. 814-820 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Proteinaceous sperm motility inhibitory factor from the female Indian garden lizard Calotes versicolor

Shankar, G., Uppangala, S., Adiga, S. K., Willard, B., Sagar, B. K. C., Titus, R. S. K. & Marathe, G. K., 01-01-2018, In : Reproduction, Fertility and Development. 30, 5, p. 744-751 8 p.

Research output: Contribution to journalArticle

Reduced expression of DNMT3B in the germ cells of patients with bilateral spermatogenic arrest does not lead to changes in the global methylation status

Adiga, S. K., Ehmcke, J., Schlatt, S., Kliesch, S., Westernströer, B., Luetjens, C. M., Wistuba, J. & Gromoll, J., 09-2011, In : Molecular Human Reproduction. 17, 9, p. 545-549 5 p., gar023.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Reduced ovarian response to controlled ovarian stimulation is associated with increased oxidative stress in the follicular environment

Uppangala, S., Fernandes, G., Salian, S. R., Kumar, P., Talevi, R., Kalthur, G. & Adiga, S. K., 01-01-2020, (Accepted/In press) In : Reproductive biology.

Research output: Contribution to journalArticle

Semen Abnormalities, Sperm DNA Damage and Global Hypermethylation in Health Workers Occupationally Exposed to Ionizing Radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Krishnamurthy, H., Jain, N., Kumar, P. & Adiga, S. K., 29-07-2013, In : PLoS One. 8, 7, e69927.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

D’Souza, F., Uppangala, S., Asampille, G., Salian, S. R., Kalthur, G., Talevi, R., Atreya, H. S. & Adiga, S. K., 01-12-2018, In : Scientific Reports. 8, 1, 17025.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract

Nayak, G., Vadinkar, A., Nair, S., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Shetty, M. M., Kalthur, G. & Adiga, S. K., 01-03-2016, In : Andrologia. 48, 2, p. 125-136 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Spermatozoada dna hasari{dotless}ni{dotless}n boyutu ile fertilizasyon ve implantasyon öncesi embriyolari{dotless}n gelişimsel kompetansi{dotless} arasi{dotless}ndaki ilişki

Translated title of the contribution: Association between the extent of DNA damage in the spermatozoa, fertilization and developmental competence in preimplantation stage embryosUpadhya, D., Kalthur, G., Kumar, P., Rao, B. S. & Adiga, S. K., 2010, In : Journal of the Turkish German Gynecology Association. 11, 4, p. 182-186 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Sperm chromatin immaturity observed in short abstinence ejaculates affects DNA integrity and longevity in vitro

Uppangala, S., Mathai, S. E., Salian, S. R., Kumar, D., Singh, V. J., D'Souza, F., Kalthur, G., Kamath, A. & Adiga, S. K., 01-04-2016, In : PLoS One. 11, 4, e0152942.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 28-11-2017, (Accepted/In press) In : Zygote. p. 1-14 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Sperm-mediated DNA lesions alter metabolite levels in spent embryo culture medium

Souza, F. D., Asampille, G., Uppangala, S., Kalthur, G., Atreya, H. S. & Adiga, S. K., 01-01-2019, In : Reproduction, Fertility and Development. 31, 3, p. 443-450 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
51 Citations (Scopus)

Successful in vitro growth of rat two-cell embryos to blastocysts using a simple chemically defined medium

Goh, V. H. H., Adiga, S. K., Tain, C. F., Tong, T. Y. Y. & Ng, S. C., 2000, In : Journal of Pharmacological and Toxicological Methods. 43, 3, p. 171-175 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Supplementation of biotin to sperm preparation medium increases the motility and longevity in cryopreserved human spermatozoa

Kalthur, G., Salian, S. R., Keyvanifard, F., Sreedharan, S., Thomas, J. S., Kumar, P. & Adiga, S. K., 07-2012, In : Journal of Assisted Reproduction and Genetics. 29, 7, p. 631-635 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Suppression of replication fork progression in low-dose-specific p53-dependent S-phase DNA damage checkpoint

Shimura, T., Toyoshima, M., Adiga, S. K., Kunoh, T., Nagai, H., Shimizu, N., Inoue, M. & Niwa, O., 28-09-2006, In : Oncogene. 25, 44, p. 5921-5932 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Survey of fertility preservation options available to patients with cancer around the globe

Rashedi, A. S., De Roo, S. F., Ataman, L. M., Edmonds, M. E., Silva, A. A., Scarella, A., Horbaczewska, A., Anazodo, A., Arvas, A., De Carvalho, B. R., Sartorio, C., Beerendonk, C. C. M., Diaz-Garcia, C., Suh, C. S., Melo, C., Andersen, C. Y., Motta, E., Greenblatt, E. M., Van Moer, E., Zand, E. & 43 others, Reis, F. M., Sánchez, F., Terrado, G., Rodrigues, J. K., De Meneses e Silva, J. M., Smitz, J., Medrano, J., Lee, J. R., Winkler-Crepaz, K., Smith, K., Melo e Silva, L. H. F., Wildt, L., Salama, M., Del Mar Andrés, M., Bourlon, M. T., Vega, M., Chehin, M. B., De Vos, M., Khrouf, M., Suzuki, N., Azmy, O., Fontoura, P., Campos-Junior, P. H. A., Mallmann, P., Azambuja, R., Marinho, R. M., Anderson, R. A., Jach, R., Antunes, R. A., Mitchell, R., Fathi, R., Adiga, S. K., Takae, S., Kim, S. H., Romero, S., Grieco, S. C., Shaulov, T., Furui, T., Almeida-Santos, T., Nelen, W., Jayasinghe, Y., Sugishita, Y. & Woodruff, T. K., 01-03-2018, In : Journal of global oncology. 2018, 4

Research output: Contribution to journalArticle

28 Citations (Scopus)

Survey of third-party parenting options associated with fertility preservation available to patients with cancer around the globe

Rashedi, A. S., De Roo, S. F., Ataman, L. M., Edmonds, M. E., Silva, A. A., Scarella, A., Horbaczewska, A., Anazodo, A., Arvas, A., De Carvalho, B. R., Sartorio, C., Beerendonk, C. C. M., Diaz-Garcia, C., Suh, C. S., Melo, C., Andersen, C. Y., Motta, E., Greenblatt, E. M., Van Moer, E., Zand, E. & 43 others, Reis, F. M., Sánchez, F., Terrado, G., Rodrigues, J. K., De Meneses e Silva, J. M., Smitz, J., Medrano, J., Lee, J. R., Winkler-Crepaz, K., Smith, K., Melo e Silva, L. H. F., Wildt, L., Salama, M., Del Mar Andrés, M., Bourlon, M. T., Vega, M., Chehin, M. B., De Vos, M., Khrouf, M., Suzuki, N., Azmy, O., Fontoura, P., Campos-Junior, P. H. A., Mallmann, P., Azambuja, R., Marinho, R. M., Anderson, R. A., Jach, R., Antunes, R. A., Mitchell, R., Fathi, R., Adiga, S. K., Takae, S., Kim, S. H., Romero, S., Grieco, S. C., Shaulov, T., Furui, T., Almeida-Santos, T., Nelen, W., Jayasinghe, Y., Sugishita, Y. & Woodruff, T. K., 01-03-2018, In : Journal of global oncology. 2018, 4

Research output: Contribution to journalArticle

17 Citations (Scopus)

Susceptibility of peripheral lymphocytes of brain tumour patients to in vitro radiation-induced DNA damage, a preliminary study

Kalthur, G., Kumar, P., Devi, U., Ali, S., Upadhya, R., Pillai, S. & Rao, A., 09-2008, In : Clinical and Experimental Medicine. 8, 3, p. 147-150 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis, anti-proliferative and genotoxicity studies of 6-chloro-5-(2-substituted-ethyl)-1,3-dihydro-2 H-indol-2-ones and 6-chloro-5-(2-chloroethyl)-3-(alkyl/ary-2-ylidene)indolin-2-ones

Meti, G. Y., Kamble, A. A., Kamble, R. R., Somagond, S. M., Devarajegowda, H. C., Kumari, S., Kalthur, G. & Adiga, S. K., 04-10-2016, In : European Journal of Medicinal Chemistry. 121, p. 221-231 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties

Castelino, P. A., Naik, P., Dasappa, J. P., Sujayraj, R. S., Sharath Chandra, K., Chaluvaiah, K., Nair, R., Sandya Kumari, M. V., Kalthur, G. & Adiga, S. K., 12-09-2014, In : European Journal of Medicinal Chemistry. 84, p. 194-199 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
8 Citations (Scopus)

Transcription-independent suppression of DNA synthesis by p53 in sperm-irradiated mouse zygotes

Toyoshima, M., Shimura, T., Adiga, S. K., Taga, M., Shiraishi, K., Inoue, M., Yuan, Z. M. & Niwa, O., 05-05-2005, In : Oncogene. 24, 20, p. 3229-3235 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
28 Citations (Scopus)