Department of Clinical Embryology, Kasturba Medical College, Manipal

  • India

Research Output 1994 2019

  • 1141 Citations
  • 21 h-Index
  • 93 Article
  • 2 Chapter
  • 1 Comment/debate
  • 1 Review article
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Article
2012
7 Citations (Scopus)
Povidone
DNA Fragmentation
Immobilization
Spermatozoa
Intracytoplasmic Sperm Injections
29 Citations (Scopus)

Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells

Khaw, A. K., Yong, J. W. Y., Kalthur, G. & Hande, M. P., 10-2012, In : Genes Chromosomes and Cancer. 51, 10, p. 961-974 14 p.

Research output: Contribution to journalArticle

Genistein
Telomerase
Brain Neoplasms
Growth
Cell Cycle Checkpoints
38 Citations (Scopus)

Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men

Varshini, J., Srinag, B. S., Kalthur, G., Krishnamurthy, H., Kumar, P., Rao, S. B. S. & Adiga, S. K., 05-2012, In : Andrologia. 44, SUPPL.1, p. 642-649 8 p.

Research output: Contribution to journalArticle

DNA Damage
Spermatozoa
Semen
Oligospermia
Varicocele
46 Citations (Scopus)
DNA Damage
Spermatozoa
In Situ Nick-End Labeling
Oligospermia
Transferases
8 Citations (Scopus)

Supplementation of biotin to sperm preparation medium increases the motility and longevity in cryopreserved human spermatozoa

Kalthur, G., Salian, S. R., Keyvanifard, F., Sreedharan, S., Thomas, J. S., Kumar, P. & Adiga, S. K., 07-2012, In : Journal of Assisted Reproduction and Genetics. 29, 7, p. 631-635 5 p.

Research output: Contribution to journalArticle

Biotin
Pentoxifylline
Spermatozoa
Semen
Semen Preservation
2011

Controlled cooling versus rapid freezing of teratozoospermic semen samples: Impact on sperm chromatin integrity

Kalludi, S. N., Kalthur, G., Benjamin, S., Kumar, P. & Adiga, S., 09-2011, In : Journal of Human Reproductive Sciences. 4, 3, p. 121-124 4 p.

Research output: Contribution to journalArticle

Semen
Freezing
Chromatin
Spermatozoa
DNA Damage
7 Citations (Scopus)

Ejaculate fractions of asthenozoospermic and teratozoospermic patients have differences in the sperm DNA integrity

Kumar, D., Kalthur, G., Mascarenhas, C., Kumar, P. & Adiga, S. K., 12-2011, In : Andrologia. 43, 6, p. 416-421 6 p.

Research output: Contribution to journalArticle

Spermatozoa
DNA
Semen
Comet Assay
Seminal Vesicles
11 Citations (Scopus)

Reduced expression of DNMT3B in the germ cells of patients with bilateral spermatogenic arrest does not lead to changes in the global methylation status

Adiga, S. K., Ehmcke, J., Schlatt, S., Kliesch, S., Westernströer, B., Luetjens, C. M., Wistuba, J. & Gromoll, J., 09-2011, In : Molecular Human Reproduction. 17, 9, p. 545-549 5 p., gar023.

Research output: Contribution to journalArticle

Germ Cells
Methylation
Spermatogenesis
5-Methylcytosine
Spermatocytes
51 Citations (Scopus)

Vitamin E supplementation in semen-freezing medium improves the motility and protects sperm from freeze-thaw-induced DNA damage

Kalthur, G., Raj, S., Thiyagarajan, A., Kumar, S., Kumar, P. & Adiga, S. K., 01-03-2011, In : Fertility and Sterility. 95, 3, p. 1149-1151 3 p.

Research output: Contribution to journalArticle

Sperm Motility
Semen
Vitamin E
Freezing
DNA Damage
2 Citations (Scopus)

yüzdürme ve dansite gradient ayi{dotless}rma metotlari{dotless}ni{dotless}n kombinasyonu DNA hasarli{dotless} spermleri etkili bir şekilde uzaklaşti{dotless}ri{dotless}r

Translated title of the contribution: Combination of swim-up and density gradient separation methods effectively eliminate DNA damaged spermGhumman, S., Adiga, S. K., Upadhya, D., Kalthur, G., Jayaraman, V., Rao, S. B. & Kumar, P., 2011, In : Journal of the Turkish German Gynecology Association. 12, 3, p. 148-152 5 p.

Research output: Contribution to journalArticle

Spermatozoa
DNA
Comet Assay
DNA Damage
Prospective Studies
2010
2 Citations (Scopus)
Insemination
Baths
Carbon Dioxide
Cost-Benefit Analysis
Spermatozoa
10 Citations (Scopus)
Melanoma
Fever
Radiotherapy
Induced Hyperthermia
Neoplasms

PPAR-gamma: A dagger in endometriosis

Amberkar, M. V., Meena Kumari, K., Mor, V., Semwal, A. & Adiga, S., 2010, In : Australasian Medical Journal. 3, 12, p. 814-820 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Spermatozoada dna hasari{dotless}ni{dotless}n boyutu ile fertilizasyon ve implantasyon öncesi embriyolari{dotless}n gelişimsel kompetansi{dotless} arasi{dotless}ndaki ilişki

Translated title of the contribution: Association between the extent of DNA damage in the spermatozoa, fertilization and developmental competence in preimplantation stage embryosUpadhya, D., Kalthur, G., Kumar, P., Rao, B. S. & Adiga, S. K., 2010, In : Journal of the Turkish German Gynecology Association. 11, 4, p. 182-186 5 p.

Research output: Contribution to journalArticle

Blastocyst
Fertilization
Mental Competency
DNA Damage
Spermatozoa
25 Citations (Scopus)
Germ Cells
Spermatozoa
Genomic Instability
DNA
DNA Damage
2009
15 Citations (Scopus)

Effect of withaferin A on the development and decay of thermotolerance in B16F1 melanoma: A preliminary study

Kalthur, G., Mutalik, S. & Pathirissery, U. D., 2009, In : Integrative Cancer Therapies. 8, 1, p. 93-97 5 p.

Research output: Contribution to journalArticle

Melanoma
Fever
Neoplasms
Withania
Protein Synthesis Inhibitors
3 Citations (Scopus)
Sperm Motility
Oocytes
Spermatozoa
Cumulus Cells
Coculture Techniques
1 Citation (Scopus)

Paternal DNA damage suppresses in vitro proliferation of mouse inner cell mass

Adiga, S. K., Toyoshima, M., Shimura, T., Takeda, J., Uematsu, N., Kumar, P. & Niwa, O., 2009, In : Journal of the Turkish German Gynecology Association. 10, 1, p. 6-9 4 p.

Research output: Contribution to journalArticle

DNA Damage
Spermatozoa
Embryonic Structures
Aptitude
DNA
3 Citations (Scopus)
Ceruloplasmin
Insemination
Acetylcholinesterase
Sulfhydryl Compounds
C-Reactive Protein
16 Citations (Scopus)
Cymbopogon
Scavenging
DNA Damage
Free Radicals
Radiation
2008
55 Citations (Scopus)
Cryopreservation
Spermatozoa
DNA Damage
DNA
Semen
9 Citations (Scopus)

Evaluation of oxidative stress, antioxidants and prolactin in infertile women

Bhaskar S, V., Upadhya, S., Adiga, S. K. & Kumar N, P., 2008, In : Indian Journal of Clinical Biochemistry. 23, 2, p. 186-190 5 p.

Research output: Contribution to journalArticle

Oxidative stress
Nitrites
Prolactin
Oxidative Stress
Antioxidants
6 Citations (Scopus)

Susceptibility of peripheral lymphocytes of brain tumour patients to in vitro radiation-induced DNA damage, a preliminary study

Kalthur, G., Kumar, P., Devi, U., Ali, S., Upadhya, R., Pillai, S. & Rao, A., 09-2008, In : Clinical and Experimental Medicine. 8, 3, p. 147-150 4 p.

Research output: Contribution to journalArticle

Lymphocytes
Brain Neoplasms
DNA Damage
Tumors
Brain
2007
3 Citations (Scopus)
Carbon Dioxide
Spermatozoa
DNA
Sperm Count
Sperm Motility
31 Citations (Scopus)

Delayed and stage specific phosphorylation of H2AX during preimplantation development of γ-irradiated mouse embryos

Adiga, S. K., Toyoshima, M., Shimura, T., Takeda, J., Uematsu, N. & Niwa, O., 02-2007, In : Reproduction. 133, 2, p. 415-422 8 p.

Research output: Contribution to journalArticle

Embryonic Structures
Phosphorylation
Radiation Tolerance
Mammalian Embryo
Radiation
36 Citations (Scopus)

p21 provides stage specific DNA damage control to preimplantation embryos

Adiga, S. K., Toyoshima, M., Shiraishi, K., Shimura, T., Takeda, J., Taga, M., Nagai, H., Kumar, P. & Niwa, O., 13-09-2007, In : Oncogene. 26, 42, p. 6141-6149 9 p.

Research output: Contribution to journalArticle

Blastocyst
DNA Damage
Embryonic Structures
Apoptosis
Spermatozoa
2006
50 Citations (Scopus)

Antioxidant, anticlastogenic and radioprotective effect of Coleus aromaticus on Chinese hamster fibroblast cells (V79) exposed to gamma radiation

Rao, B. S. S., Shanbhoge, R., Upadhya, D., Jagetia, G. C., Adiga, S. K., Kumar, P., Guruprasad, K. & Gayathri, P., 07-2006, In : Mutagenesis. 21, 4, p. 237-242 6 p.

Research output: Contribution to journalArticle

Coleus
Gamma Rays
Scavenging
Fibroblasts
Cricetulus
Estradiol
Ovarian Hyperstimulation Syndrome
Oocytes
Serum
Intracytoplasmic Sperm Injections
26 Citations (Scopus)

Suppression of replication fork progression in low-dose-specific p53-dependent S-phase DNA damage checkpoint

Shimura, T., Toyoshima, M., Adiga, S. K., Kunoh, T., Nagai, H., Shimizu, N., Inoue, M. & Niwa, O., 28-09-2006, In : Oncogene. 25, 44, p. 5921-5932 12 p.

Research output: Contribution to journalArticle

S Phase
DNA Damage
Fibroblasts
Proliferating Cell Nuclear Antigen
DNA
2005
17 Citations (Scopus)

Transcription-independent suppression of DNA synthesis by p53 in sperm-irradiated mouse zygotes

Toyoshima, M., Shimura, T., Adiga, S. K., Taga, M., Shiraishi, K., Inoue, M., Yuan, Z. M. & Niwa, O., 05-05-2005, In : Oncogene. 24, 20, p. 3229-3235 7 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
Zygote
Spermatozoa
DNA
Phosphorylation
2002
8 Citations (Scopus)

Androgen Receptor Expression and DNA Content of Paraffin-Embedded Archival Human Prostate Tumors

Adiga, S. K., Andritsch, I., Rao, R. V. & Krishan, A., 15-02-2002, In : Clinical Cytometry. 50, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

Androgen Receptors
Paraffin
Prostate
DNA
Neoplasms
4 Citations (Scopus)
Follicular Fluid
Ovulation
L-Lactate Dehydrogenase
Superovulation
Estradiol
2001
9 Citations (Scopus)
Andrology
Semen
Spermatozoa
Sperm Count
Sperm Motility
2000
12 Citations (Scopus)
Vindesine
Cell Survival
Radiation
Growth
Gamma Rays
3 Citations (Scopus)

Direct effects of varying doses of oestradiol on early embryonic development in in vitro culture of rat's two-cell embryos

Tong, T. Y. Y., Goh, V. H. H., Tain, C. F., Mok, H., Tsang, S. & Adiga, S. K., 2000, In : Canadian Journal of Physiology and Pharmacology. 78, 6, p. 453-456 4 p.

Research output: Contribution to journalArticle

Embryonic Development
Estradiol
Embryonic Structures
Equine Gonadotropins
Blastocyst
3 Citations (Scopus)

Successful in vitro growth of rat two-cell embryos to blastocysts using a simple chemically defined medium

Goh, V. H. H., Adiga, S. K., Tain, C. F., Tong, T. Y. Y. & Ng, S. C., 2000, In : Journal of Pharmacological and Toxicological Methods. 43, 3, p. 171-175 5 p.

Research output: Contribution to journalArticle

Blastocyst
Rats
Embryonic Structures
Glucose
Glutamine
1999
12 Citations (Scopus)
Teniposide
L-Lactate Dehydrogenase
Dosimetry
Cell Survival
Cells
16 Citations (Scopus)

Effect of teniposide (VM-26) on the cell survival, micronuclei-induction and lactate dehydrogenase activity on V79 cells

Adiga, S. K. & Jagetia, G. C., 29-10-1999, In : Toxicology. 138, 1, p. 29-41 13 p.

Research output: Contribution to journalArticle

Teniposide
L-Lactate Dehydrogenase
Cell Survival
Cells
Growth kinetics
1998
12 Citations (Scopus)
Vindesine
Cell Survival
Cricetulus
Pharmaceutical Preparations
Fibroblasts
1997
21 Citations (Scopus)
Paclitaxel
Cell Survival
Radiation
Cell Proliferation
Control Groups
1995
24 Citations (Scopus)

Influence of various concentrations of taxol on cell survival, micronuclei induction, and LDH activity in cultured V79 cells

Jagetia, G. C. & Adiga, S. K., 25-09-1995, In : Cancer Letters. 96, 2, p. 195-200 6 p.

Research output: Contribution to journalArticle

Paclitaxel
Cultured Cells
Cell Survival
L-Lactate Dehydrogenase
1994
18 Citations (Scopus)
Cadmium Chloride
Erythrocytes
Bone Marrow
Body Weight