Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

Research Output 1989 2018

2018

Antiplaque efficacy of ganoderma lucidum toothpaste-an in vitro study

Prabhjeet, S., Meena, A. K. & Jesil, M., 01-01-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 11, p. 300-303 4 p.

Research output: Contribution to journalArticle

Reishi
Mouthwashes
Toothpastes
Chlorhexidine
Erythrosine
1 Citation (Scopus)

Exploring the potential of marine microbes in clinical management of Alzheimer's disease: A road map for bioprospecting and identifying promising isolates

Muralidharan, A., Josyula, V. R. & Hariharapura, R. C., 01-09-2018, In : Life Sciences. 208, p. 149-160 12 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Cholinergic Agents
Disease Progression
Pharmaceutical Preparations
Metabolites

In silico studies, synthesis and anticancer activity of novel diphenyl ether-based pyridine derivatives

Verma, R., Bairy, I., Tiwari, M., Bhat, G. V. & Shenoy, G. G., 01-01-2018, (Accepted/In press) In : Molecular Diversity.

Research output: Contribution to journalArticle

Computer Simulation
Pyridine
Ethers
ethers
pyridines
Chalcones
Tumors
Cells
Cytotoxicity
Doxorubicin

Pinocembrin-Enriched Fractions of Elytranthe parasitica (L.) Danser Modulates Apoptotic and MAPK Cellular Signaling in HepG2 Cells

Kumar, N., Shrungeswara, A. H., Mallik, S. B., Biswas, S., Mathew, J., Nandakumar, K., Mathew, J. & Lobo, R., 01-01-2018, In : Anti-cancer agents in medicinal chemistry. 18, 11, p. 1563-1572 10 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Protein Kinases
Apoptosis
Hepatocellular Carcinoma
Phytochemicals

Propargylamine (secondary) as a building block in indole synthesis involving ultrasound assisted Pd/Cu-catalyzed coupling-cyclization method: Unexpected formation of (pyrazole)imine derivatives

Sujeevan Reddy, G., Babu Nallapati, S., Sri Saranya, P. S. V. K., Sridhar, B., Bhat Giliyaru, V., Chandrashekhar Hariharapura, R., Gautham Shenoy, G. & Pal, M., 26-12-2018, In : Tetrahedron Letters. 59, 52, p. 4587-4592 6 p.

Research output: Contribution to journalArticle

Indoles
Imines
Cyclization
Ultrasonics
Derivatives
1 Citation (Scopus)

Serum-derived IgG from coxsackievirus A6-infected patients can enhance the infection of peripheral blood mononuclear cells with coxsackievirus A6

Aswathyraj, S., Sane, F., Raghu, C., Sabeena, S., Alidjinou, E. K., Arunkumar, G. & Hober, D., 01-12-2018, In : Microbial Pathogenesis. 125, p. 7-11 5 p.

Research output: Contribution to journalArticle

Enterovirus
Blood Cells
Immunoglobulin G
Coxsackievirus Infections
Infection

Strategies for improving the specificity of siRNAs for enhanced therapeutic potential

Gatta, A. K., Hariharapura, R. C., Udupa, N., Reddy, M. S. & Josyula, V. R., 03-08-2018, In : Expert Opinion on Drug Discovery. 13, 8, p. 709-725 17 p.

Research output: Contribution to journalReview article

Small Interfering RNA
RNA Interference
Therapeutics
Expert Testimony
Endocytosis
12 Citations (Scopus)

Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

Rajagopal, C., Lankadasari, M. B., Aranjani, J. M. & Harikumar, K. B., 01-04-2018, In : Pharmacological Research. 130, p. 273-291 19 p.

Research output: Contribution to journalReview article

Polyphenols
Transcription Factors
Neoplasms
Inflammation
Biological Products
2017
Dipterocarpaceae
lissamine rhodamine B
Cell Line
India
Neoplasms
1 Citation (Scopus)

Application of molecular descriptors in modern computational drug design – An overview

Kamath, V. & Pai, A., 01-09-2017, In : Research Journal of Pharmacy and Technology. 10, 9, p. 3237-3241 5 p.

Research output: Contribution to journalReview article

Ecotoxicology
Quantitative Structure-Activity Relationship
Environmental Health
Drug Design
Molecular Structure
3 Citations (Scopus)

BRAF, KRAS and PIK3CA mutation and sensitivity to Trastuzumab in breast cancer cell line model

Patra, S., Young, V., Llewellyn, L., Senapati, J. N. & Mathew, J., 2017, In : Asian Pacific Journal of Cancer Prevention. 18, 8, p. 2209-2213 5 p.

Research output: Contribution to journalArticle

Decitabine nanoparticles supplement docetaxel in the treatment of non-small cell lung cancer (NSCLC)

Jain, P., Kumar, N., Tiwari, M., Rao, J. V. & Udupa, N., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1921-1924 4 p.

Research output: Contribution to journalArticle

decitabine
docetaxel
Lung Cancer
Non-Small Cell Lung Carcinoma
Nanoparticles
2 Citations (Scopus)

Design, synthesis and biological evaluation of oxindole-based chalcones as small-molecule inhibitors of melanogenic tyrosinase

Suthar, S. K., Bansal, S., Narkhede, N., Guleria, M., Alex, A. T. & Joseph, A., 2017, In : Chemical and Pharmaceutical Bulletin. 65, 9, p. 833-839 7 p.

Research output: Contribution to journalArticle

Chalcones
Monophenol Monooxygenase
Chalcone
Molecules
Bearings (structural)

Development and evaluation of orodispersible tablet of microwave generated co-processed material of carbamazepine

Chonkar, A., Hardikar, S., Venkata Rao, J. & Udupa, N., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1899-1903 5 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Carbamazepine
Microwaves
Tablets
Microwave

Fungal chondroitinase: Production and prospects for therapeutic application

Narayanan, K., Sivagurunathan, N., Subrahmanyam, V. M. & Rao, J. V., 07-11-2017, Recent advances in Applied Microbiology. Springer Science+Business Media Singapore Private Limited, p. 275-290 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chondroitinases and Chondroitin Lyases
Fungi
Chondroitin Sulfates
MCF-7 Cells
Enzymes

Interactions of phytic acid with anticancer drug targets

Joy, A. & Balaji, S., 2017, In : International Journal of Computational Biology and Drug Design. 10, 1, p. 49-62 14 p.

Research output: Contribution to journalArticle

Phytic Acid
Inositol 1,4,5-Trisphosphate Receptors
Acids
Pharmaceutical Preparations
Proteins

In vitro analysis of 4-methylumbelliferone as a sole carbon source for Lactobacillus helveticus 2126

Madhoolika, B., Anil Kumar, N. V. & Balaji, S., 01-09-2017, In : Letters in Applied Microbiology. 65, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Hymecromone
Lactobacillus helveticus
Carbon
Prebiotics
Microbiota
9 Citations (Scopus)

Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data

Vastrad, B., Vastrad, C., Godavarthi, A. & Chandrashekar, R., 01-11-2017, In : Medical Oncology. 34, 11, 182.

Research output: Contribution to journalArticle

Glioblastoma
Microarray Analysis
Computational Biology
Glioma
Genes
2 Citations (Scopus)

Oral candidal speciation, virulence and antifungal susceptibility in type 2 diabetes mellitus

Patel, P. N., Sah, P., Chandrashekar, C., Vidyasagar, S., Venkata Rao, J., Tiwari, M. & Radhakrishnan, R., 01-03-2017, In : Diabetes Research and Clinical Practice. 125, p. 10-19 10 p.

Research output: Contribution to journalArticle

Fluconazole
Type 2 Diabetes Mellitus
Virulence
Candida
Virulence Factors
5 Citations (Scopus)

Phytases of Probiotic Bacteria: Characteristics and Beneficial Aspects

Priyodip, P., Prakash, P. Y. & Balaji, S., 01-06-2017, In : Indian Journal of Microbiology. 57, 2, p. 148-154 7 p.

Research output: Contribution to journalReview article

6-Phytase
Probiotics
Phytic Acid
Bacteria
Minerals

Preliminary studies on chemical constituents and antimicrobial activities of Psidium guajava Linn

Ranjan, D., Deogam, A., Polu, P. R., Khan, S. & Rao, J. V., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

Psidium
antimicrobial activity
Quercetin
Medicine
Escherichia coli
2 Citations (Scopus)

Promising anticancer activities of Justicia simplex D. Don. in cellular and animal models

Joseph, L., Aranjani, J. M., Pai, K. S. R. & Srinivasan, K. K., 06-03-2017, In : Journal of Ethnopharmacology. 199, p. 231-239 9 p.

Research output: Contribution to journalArticle

Justicia
Animal Models
Vascular Endothelial Growth Factor A
Neoplasms
Growth
1 Citation (Scopus)
Bacillus cereus
Biosynthesis
Copper
Nanoparticles
copper

Screening of soil samples for isolation of lipase producing organisms

Kumar, M., Deogam, A., Tiwari, M. & Kamath, V., 2017, In : Research Journal of Pharmacy and Technology. 10, 6, p. 1730-1733 4 p.

Research output: Contribution to journalArticle

Lipase
Agar
Soil
Bacteria
Industry
21 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Antioxidants
Radiation
Skin
Differential Scanning Calorimetry
Arsenic
Poisons
Spectrum Analysis
Metalloids
X-Rays

Study of airborne bacterial load in indoor environments

Gandhi, N., Tawale, R., Muralidharan, A., Jesil Mathew, A. & Alex, A. T., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1910-1913 4 p.

Research output: Contribution to journalArticle

Bacterial Load
Air
air
classroom
Microorganisms
2016
1 Citation (Scopus)

A novel conformation generation framework for de novo protein structure prediction using hydrophobic-polar model

Dubey, S. P. N., Gopalakrishna Kini, N., Sathish Kumar, M., Balaji, S., Sumana Bhat, M. P. & Kavathiyal, H. R., 2016, In : Asian Journal of Biochemistry. 11, 3, p. 149-155 7 p.

Research output: Contribution to journalArticle

Conformations
Proteins
Anethum graveolens
Benchmarking
Protein Conformation
4 Citations (Scopus)

Antiapoptotic Bcl-2 protein as a potential target for cancer therapy: A mini review

Jagani, H., Kasinathan, N., Meka, S. R. & Venkata Rao, J., 03-07-2016, In : Artificial Cells, Nanomedicine and Biotechnology. 44, 5, p. 1212-1221 10 p.

Research output: Contribution to journalReview article

RNA Interference
RNA
Proteins
bcl-2 Genes
Antisense RNA
8 Citations (Scopus)

Biosynthesis of copper nanoparticles using copper-resistant Bacillus cereus, a soil isolate

Tiwari, M., Jain, P., Chandrashekhar Hariharapura, R., Narayanan, K., Bhat K., U., Udupa, N. & Rao, J. V., 01-10-2016, In : Process Biochemistry. 51, 10, p. 1348-1356 9 p.

Research output: Contribution to journalArticle

Bacillus cereus
Biosynthesis
Nanoparticles
Copper
Soil
5 Citations (Scopus)

Chondroitinase: A promising therapeutic enzyme

Kasinathan, N., Volety, S. M. & Josyula, V. R., 03-05-2016, In : Critical Reviews in Microbiology. 42, 3, p. 474-484 11 p.

Research output: Contribution to journalReview article

Chondroitinases and Chondroitin Lyases
Chondroitin Sulfate Proteoglycans
Enzymes
Therapeutics
Drug Delivery Systems
1 Citation (Scopus)

Cognitive enhancement and neuroprotective effects of ancient ayurvedic medicinal plant celastrus paniculatus: An overview

Pai, V., Shreedhara, C. S., Chandrashekar, K. S., Pai, A. & Kamath, V., 01-08-2016, In : Research Journal of Pharmacy and Technology. 9, 8, p. 1295-1298 4 p.

Research output: Contribution to journalReview article

Celastrus
Neuroprotective Agents
Medicinal Plants
Dementia
Alzheimer Disease
decitabine
docetaxel
9,10-Dimethyl-1,2-benzanthracene
Nanoparticles
Sprague Dawley Rats
8 Citations (Scopus)

Development and evaluation of carboplatin-loaded PCL nanoparticles for intranasal delivery

Alex, A. T., Joseph, A., Shavi, G., Rao, J. V. & Udupa, N., 01-09-2016, In : Drug Delivery. 23, 7, p. 2144-2153 10 p.

Research output: Contribution to journalArticle

Carboplatin
Nanoparticles
Nose
Intranasal Administration
Brain
14 Citations (Scopus)
Nanoparticles
Biological Availability
Permeability
Mouth Mucosa
Angina Pectoris
4 Citations (Scopus)

In-situ implant containing PCL-curcumin nanoparticles developed using design of experiments

Kasinathan, N., Amirthalingam, M., Reddy, N. D., Jagani, H. V., Volety, S. M. & Rao, J. V., 23-03-2016, In : Drug Delivery. 23, 3, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Curcumin
Ascites
Nanoparticles
Polymers
Carcinoma

In vitro wound-healing effects of biosynthesized copper nanoparticles

Tiwari, M., Jain, P., Hariharpura, R. C., Udupa, N. & Rao, J. V., 01-02-2016, In : Asian Journal of Pharmaceutical Sciences. 11, 1, p. 158-159 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
Phenol
Phenols
Wastewater
Mass transfer
Adsorption
2 Citations (Scopus)
decitabine
K562 Cells
S Phase
Nanoparticles
Oral Administration
2 Citations (Scopus)

Polycaprolactone-based in situ implant containing curcumin-PLGA nanoparticles prepared using the multivariate technique

Kasinathan, N., Amirthalingam, M., Reddy, N. D., Vanthi, M. B., Volety, S. M. & Rao, J. V., 17-08-2016, In : Artificial Cells, Nanomedicine and Biotechnology. 44, 6, p. 1520-1528 9 p.

Research output: Contribution to journalArticle

Polycaprolactone
Curcumin
Nanoparticles
Sonication
Encapsulation
6 Citations (Scopus)
Hepatocellular Carcinoma
Loranthaceae
Ether
Gallic Acid
Acridine Orange
2015
Activated carbon
Adsorbents
Dyes
Mathematical models
Adsorption
2 Citations (Scopus)

A pulse radiolysis study of hyperoside isolated from Hypericum mysorense

Hariharapura, R. C., Mahal, H. S., Srinivasan, R., Jagani, H. & Vijayan, P., 2015, In : Radiation Physics and Chemistry. 107, p. 149-159 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A review on response of immune system in spinal cord injury and therapeutic agents useful in treatment

Kasinathan, N., Vanathi, M. B., Subrahmanyam, V. M. & Rao, J. V., 2015, In : Current Pharmaceutical Biotechnology. 16, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents

Suthar, S. K., Bansal, S., Alam, M. M., Jaiswal, V., Tiwari, A., Chaudhary, A., Alex, A. T. & Joseph, A., 15-11-2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 22, p. 5281-5285 5 p.

Research output: Contribution to journalArticle

Imipramine
Monoamine Oxidase
Antidepressive Agents
Inhibitory Concentration 50
Assays
2 Citations (Scopus)

Design of cultural conditions for production of chondroitinase by aspergillus Niger using design of experiments

Kasinathan, N., Subrahmanyam, V. M. & Josyula, V. R., 2015, In : Indian Drugs. 52, 6, p. 24-32 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Drug-likeness of phytic acid and its analogues

Joy, A. & Balaji, S., 2015, In : Open Microbiology Journal. 9, p. 141-149 9 p., A1.

Research output: Contribution to journalArticle

Phytic Acid
Pharmaceutical Preparations
Inositol 1,4,5-Trisphosphate Receptors
Structure-Activity Relationship
Computational Biology