Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

Research Output 1989 2019

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Article
2019
Polyhydroxyalkanoates
Molasses
Bacilli
Feedstocks
Carbon

Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM)

Reddy, G. S., Snehalatha, A. V., Edwin, R. K., Hossain, K. A., Giliyaru, V. B., Hariharapura, R. C., Gautham Shenoy, G., Misra, P. & Pal, M., 01-10-2019, In : Bioorganic Chemistry. 91, 103155.

Research output: Contribution to journalArticle

Chorismate Mutase
Catalysis
Derivatives
Antitubercular Agents
Cyclization
Antidiarrheals
Flavonoids
Antioxidants
Castor Oil
Formularies
2018

Antiplaque efficacy of ganoderma lucidum toothpaste-an in vitro study

Prabhjeet, S., Meena, A. K. & Jesil, M., 01-01-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 11, p. 300-303 4 p.

Research output: Contribution to journalArticle

Reishi
Mouthwashes
Toothpastes
Chlorhexidine
Erythrosine

Investigating the potential of tetrahydropyridinyl chalcones as useful agents against breast carcinoma: An in vitro and in vivo study

Nigam, S., Jayashree, B. S., Pande, A. N., Reddy, N. D. & Rao, V. J., 01-02-2018, In : Research on Chemical Intermediates. p. 1-24 24 p.

Research output: Contribution to journalArticle

Chalcones
Tumors
Cells
Cytotoxicity
Doxorubicin

Propargylamine (secondary) as a building block in indole synthesis involving ultrasound assisted Pd/Cu-catalyzed coupling-cyclization method: Unexpected formation of (pyrazole)imine derivatives

Sujeevan Reddy, G., Babu Nallapati, S., Sri Saranya, P. S. V. K., Sridhar, B., Bhat Giliyaru, V., Chandrashekhar Hariharapura, R., Gautham Shenoy, G. & Pal, M., 26-12-2018, In : Tetrahedron Letters. 59, 52, p. 4587-4592 6 p.

Research output: Contribution to journalArticle

Indoles
Imines
Cyclization
Ultrasonics
Derivatives
1 Citation (Scopus)

Serum-derived IgG from coxsackievirus A6-infected patients can enhance the infection of peripheral blood mononuclear cells with coxsackievirus A6

Aswathyraj, S., Sane, F., Raghu, C., Sabeena, S., Alidjinou, E. K., Arunkumar, G. & Hober, D., 01-12-2018, In : Microbial Pathogenesis. 125, p. 7-11 5 p.

Research output: Contribution to journalArticle

Enterovirus
Blood Cells
Immunoglobulin G
Coxsackievirus Infections
Infection
2017
Dipterocarpaceae
lissamine rhodamine B
Cell Line
India
Neoplasms

Decitabine nanoparticles supplement docetaxel in the treatment of non-small cell lung cancer (NSCLC)

Jain, P., Kumar, N., Tiwari, M., Rao, J. V. & Udupa, N., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1921-1924 4 p.

Research output: Contribution to journalArticle

decitabine
docetaxel
Lung Cancer
Non-Small Cell Lung Carcinoma
Nanoparticles
2 Citations (Scopus)

Design, synthesis and biological evaluation of oxindole-based chalcones as small-molecule inhibitors of melanogenic tyrosinase

Suthar, S. K., Bansal, S., Narkhede, N., Guleria, M., Alex, A. T. & Joseph, A., 2017, In : Chemical and Pharmaceutical Bulletin. 65, 9, p. 833-839 7 p.

Research output: Contribution to journalArticle

Chalcones
Monophenol Monooxygenase
Chalcone
Molecules
Bearings (structural)

Development and evaluation of orodispersible tablet of microwave generated co-processed material of carbamazepine

Chonkar, A., Hardikar, S., Venkata Rao, J. & Udupa, N., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1899-1903 5 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Carbamazepine
Microwaves
Tablets
Microwave

Interactions of phytic acid with anticancer drug targets

Joy, A. & Balaji, S., 2017, In : International Journal of Computational Biology and Drug Design. 10, 1, p. 49-62 14 p.

Research output: Contribution to journalArticle

Phytic Acid
Inositol 1,4,5-Trisphosphate Receptors
Acids
Pharmaceutical Preparations
Proteins

In vitro analysis of 4-methylumbelliferone as a sole carbon source for Lactobacillus helveticus 2126

Madhoolika, B., Anil Kumar, N. V. & Balaji, S., 01-09-2017, In : Letters in Applied Microbiology. 65, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Hymecromone
Lactobacillus helveticus
Carbon
Prebiotics
Microbiota
10 Citations (Scopus)

Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data

Vastrad, B., Vastrad, C., Godavarthi, A. & Chandrashekar, R., 01-11-2017, In : Medical Oncology. 34, 11, 182.

Research output: Contribution to journalArticle

Glioblastoma
Microarray Analysis
Computational Biology
Glioma
Genes
2 Citations (Scopus)

Oral candidal speciation, virulence and antifungal susceptibility in type 2 diabetes mellitus

Patel, P. N., Sah, P., Chandrashekar, C., Vidyasagar, S., Venkata Rao, J., Tiwari, M. & Radhakrishnan, R., 01-03-2017, In : Diabetes Research and Clinical Practice. 125, p. 10-19 10 p.

Research output: Contribution to journalArticle

Fluconazole
Type 2 Diabetes Mellitus
Virulence
Candida
Virulence Factors

Preliminary studies on chemical constituents and antimicrobial activities of Psidium guajava Linn

Ranjan, D., Deogam, A., Polu, P. R., Khan, S. & Rao, J. V., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

Psidium
antimicrobial activity
Quercetin
Medicine
Escherichia coli
2 Citations (Scopus)

Promising anticancer activities of Justicia simplex D. Don. in cellular and animal models

Joseph, L., Aranjani, J. M., Pai, K. S. R. & Srinivasan, K. K., 06-03-2017, In : Journal of Ethnopharmacology. 199, p. 231-239 9 p.

Research output: Contribution to journalArticle

Justicia
Animal Models
Vascular Endothelial Growth Factor A
Neoplasms
Growth
1 Citation (Scopus)

Quality by design: Optimization of media components and factors affecting biosynthesis of copper nanoparticles by Bacillus cereus

Tiwari, M., Udupa, N. & Rao, J. V., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1792-1797 6 p.

Research output: Contribution to journalArticle

Bacillus cereus
Biosynthesis
Copper
Nanoparticles
copper

Screening of soil samples for isolation of lipase producing organisms

Kumar, M., Deogam, A., Tiwari, M. & Kamath, V., 2017, In : Research Journal of Pharmacy and Technology. 10, 6, p. 1730-1733 4 p.

Research output: Contribution to journalArticle

Lipase
Agar
Soil
Bacteria
Industry
25 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Antioxidants
Radiation
Skin
Differential Scanning Calorimetry
Arsenic
Poisons
Spectrum Analysis
Metalloids
X-Rays

Study of airborne bacterial load in indoor environments

Gandhi, N., Tawale, R., Muralidharan, A., Jesil Mathew, A. & Alex, A. T., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1910-1913 4 p.

Research output: Contribution to journalArticle

Bacterial Load
Air
air
classroom
Microorganisms
2016
1 Citation (Scopus)

A novel conformation generation framework for de novo protein structure prediction using hydrophobic-polar model

Dubey, S. P. N., Gopalakrishna Kini, N., Sathish Kumar, M., Balaji, S., Sumana Bhat, M. P. & Kavathiyal, H. R., 2016, In : Asian Journal of Biochemistry. 11, 3, p. 149-155 7 p.

Research output: Contribution to journalArticle

Conformations
Proteins
Anethum graveolens
Benchmarking
Protein Conformation
8 Citations (Scopus)

Biosynthesis of copper nanoparticles using copper-resistant Bacillus cereus, a soil isolate

Tiwari, M., Jain, P., Chandrashekhar Hariharapura, R., Narayanan, K., Bhat K., U., Udupa, N. & Rao, J. V., 01-10-2016, In : Process Biochemistry. 51, 10, p. 1348-1356 9 p.

Research output: Contribution to journalArticle

Bacillus cereus
Biosynthesis
Nanoparticles
Copper
Soil

Decitabine nanoparticles and docetaxel combination shrinks mammary carcinoma induced by DMBA in female sprague-dawley rats

Jain, P., Kumar, N., Tiwari, M., Rao, J. V., Shilpee, C. & Udupa, N., 01-10-2016, In : International Journal of Toxicological and Pharmacological Research. 8, 5, p. 397-405 9 p.

Research output: Contribution to journalArticle

decitabine
docetaxel
9,10-Dimethyl-1,2-benzanthracene
Nanoparticles
Sprague Dawley Rats
12 Citations (Scopus)

Development and evaluation of carboplatin-loaded PCL nanoparticles for intranasal delivery

Alex, A. T., Joseph, A., Shavi, G., Rao, J. V. & Udupa, N., 01-09-2016, In : Drug Delivery. 23, 7, p. 2144-2153 10 p.

Research output: Contribution to journalArticle

Carboplatin
Nanoparticles
Nose
Intranasal Administration
Brain
16 Citations (Scopus)
Nanoparticles
Biological Availability
Permeability
Mouth Mucosa
Angina Pectoris
5 Citations (Scopus)

In-situ implant containing PCL-curcumin nanoparticles developed using design of experiments

Kasinathan, N., Amirthalingam, M., Reddy, N. D., Jagani, H. V., Volety, S. M. & Rao, J. V., 23-03-2016, In : Drug Delivery. 23, 3, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Curcumin
Ascites
Nanoparticles
Polymers
Carcinoma

In vitro wound-healing effects of biosynthesized copper nanoparticles

Tiwari, M., Jain, P., Hariharpura, R. C., Udupa, N. & Rao, J. V., 01-02-2016, In : Asian Journal of Pharmaceutical Sciences. 11, 1, p. 158-159 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
Phenol
Phenols
Wastewater
Mass transfer
Adsorption
2 Citations (Scopus)
decitabine
K562 Cells
S Phase
Nanoparticles
Oral Administration
3 Citations (Scopus)
2 Citations (Scopus)

Polycaprolactone-based in situ implant containing curcumin-PLGA nanoparticles prepared using the multivariate technique

Kasinathan, N., Amirthalingam, M., Reddy, N. D., Vanthi, M. B., Volety, S. M. & Rao, J. V., 17-08-2016, In : Artificial Cells, Nanomedicine and Biotechnology. 44, 6, p. 1520-1528 9 p.

Research output: Contribution to journalArticle

Polycaprolactone
Curcumin
Nanoparticles
Sonication
Encapsulation
6 Citations (Scopus)
Hepatocellular Carcinoma
Loranthaceae
Ether
Gallic Acid
Acridine Orange
2015
Activated carbon
Adsorbents
Dyes
Mathematical models
Adsorption
2 Citations (Scopus)

A pulse radiolysis study of hyperoside isolated from Hypericum mysorense

Hariharapura, R. C., Mahal, H. S., Srinivasan, R., Jagani, H. & Vijayan, P., 2015, In : Radiation Physics and Chemistry. 107, p. 149-159 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A review on response of immune system in spinal cord injury and therapeutic agents useful in treatment

Kasinathan, N., Vanathi, M. B., Subrahmanyam, V. M. & Rao, J. V., 2015, In : Current Pharmaceutical Biotechnology. 16, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents

Suthar, S. K., Bansal, S., Alam, M. M., Jaiswal, V., Tiwari, A., Chaudhary, A., Alex, A. T. & Joseph, A., 15-11-2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 22, p. 5281-5285 5 p.

Research output: Contribution to journalArticle

Imipramine
Monoamine Oxidase
Antidepressive Agents
Inhibitory Concentration 50
Assays
2 Citations (Scopus)

Design of cultural conditions for production of chondroitinase by aspergillus Niger using design of experiments

Kasinathan, N., Subrahmanyam, V. M. & Josyula, V. R., 2015, In : Indian Drugs. 52, 6, p. 24-32 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Drug-likeness of phytic acid and its analogues

Joy, A. & Balaji, S., 2015, In : Open Microbiology Journal. 9, p. 141-149 9 p., A1.

Research output: Contribution to journalArticle

Phytic Acid
Pharmaceutical Preparations
Inositol 1,4,5-Trisphosphate Receptors
Structure-Activity Relationship
Computational Biology
1 Citation (Scopus)
4 Citations (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated intrinsic pathway

Sankhe, N. M., Durgashivaprasad, E., Gopalan Kutty, N., Venkata Rao, J., Narayanan, K., Kumar, N., Jain, P., Udupa, N. & Vasanth Raj, P., 31-07-2015, (Accepted/In press) In : Arabian Journal of Chemistry.

Research output: Contribution to journalArticle

Cell death
Cells
Apoptosis
Derivatives
DNA
Purine-Nucleoside Phosphorylase
Preclinical Drug Evaluations
Schistosoma mansoni
Screening
Schistosoma
2014
21 Citations (Scopus)
1 Citation (Scopus)

Biofilm production and antibiotic susceptibility of planktonic and biofilm bacteria of canine dental tartar isolates

Manuel, A., Rao, J. V., John, K. & Aranjani, J. M., 2014, In : Acta Scientiae Veterinariae. 42, 1

Research output: Contribution to journalArticle

1 Citation (Scopus)

Bioprospecting for Cyclodextrin Glycosyltransferase producing bacteria

Rajesh, Y., Narayanan, K., Subrahmanyam, V. M. & Venkata Rao, J., 2014, In : Indian Drugs. 51, 6, p. 44-48 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Biosynthesis and wound healing activity of copper nanoparticles

Tiwari, M., Narayanan, K., Thakar, M. B., Jagani, H. V. & Rao, J. V., 2014, In : IET Nanobiotechnology. 8, 4, p. 230-237 8 p.

Research output: Contribution to journalArticle

Immunomodulatory activity of complementary and alternative medicines

Bhaskaran-Nair Harikumar, K., Hardman, R., Aranjani, J. M., Vimala Raveendran, V. & Thejass, P., 2014, In : Evidence-based Complementary and Alternative Medicine. 2014

Research output: Contribution to journalArticle

8 Citations (Scopus)
Mastitis
Biofilms
milk composition
Bacterial Infections
biofilm