Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

  • India

Research Output

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Article
2015

Molecular docking, pharmacophore modeling and 3D-QSAR approach on a series of piperidone derivatives as potential anticancer agents by targeting the enzyme VEGFR-2 tyrosine kinase

Rajappan, R., Ramachandran, V. P., Ranganath Pai, K. S., Arunkumar, G., Rao, J. V., Jagani, H. & Kini, S. G., 2015, In : Der Pharma Chemica. 7, 4, p. 155-163 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nephroprotective potential of Graptophyllum pictum against renal injury induced by gentamicin

Srinivasan, K. K., Mathew, J. E., A.D’Silva, K. J., Lobo, R. & Kumar, N., 2015, In : Iranian Journal of Basic Medical Sciences. 18, 4, p. 412-416 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Production of β -cyclodextrin from pH and thermo stable cyclodextrin glycosyl transferase, obtained from Arthrobacter mysorens and its evaluation as a drug carrier for irbesartan

Rajesh, Y., Narayanan, K., Reddy, M. S., Bhaskar, V. K., Shenoy, G. G., Subrahmanyam, V. M. & Rao, J. V., 2015, In : Current Drug Delivery. 12, 4, p. 444-453 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of quinolinyl-oxadiazole as a potent antibacterial agent and Sa-Fabi inhibitor

Sunil, D., D’Almeida, L., Kini, S. G. & Rama, M., 2015, In : International Journal of Pharmacy and Pharmaceutical Sciences. 7, 8, p. 105-109 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Targets in anticancer research-a review

Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In : Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Anticancer evaluation of some of the novel iminoflavones

Jayashree, B. S., Kawade, S. & Venkatachalam, H., 2014, In : Research Journal of Chemistry and Environment. 18, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Antidiabetic activity of 3-hydroxyflavone analogues in high fructose fed insulin resistant rats

Nayak, Y., Venkatachalam, H., Daroji, V. K., Mathew, G., Jayashree, B. S. & Unnikrishnan, M. K., 09-09-2014, In : EXCLI Journal. 13, p. 1055-1074 20 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Antidiabetic activity of benzopyrone analogues in nicotinamide-streptozotocin induced type 2 diabetes in rats

Nayak, Y., Hillemane, V., Daroji, V. K., Jayashree, B. S. & Unnikrishnan, M. K., 2014, In : Scientific World Journal. 2014, 854267.

Research output: Contribution to journalArticle

12 Citations (Scopus)
4 Citations (Scopus)
7 Citations (Scopus)
7 Citations (Scopus)

Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1, 3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity

Bansal, S., Bala, M., Suthar, S. K., Choudhary, S., Bhattacharya, S., Bhardwaj, V., Singla, S. & Joseph, A., 2014, In : European Journal of Medicinal Chemistry. 80, p. 167-174 8 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

From phytochemistry to medicinal chemistry: Isolation, semisynthesis, evaluation and computational studies

Singla, R. K., Varadaraj Bhat, G. & Gonzalez-Diaz, H., 2014, In : Current Topics in Medicinal Chemistry. 14, 8, p. 979-980 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In : BioMed Research International. 2014, 569130.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Insights on the antioxidant potential of 1, 2, 4-triazoles: Synthesis, screening & QSAR studies

Pokuri, S., Singla, R. K., Bhat, V. G. & Shenoy, G. G., 2014, In : Current Drug Metabolism. 15, 4, p. 389-397 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In : Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
61 Citations (Scopus)
2 Citations (Scopus)

Synthesis, antimicrobial and docking studies of novel benzotriazole derivatives

Kumar, P. B., Kini, S. G. & Mubeen, M., 2014, In : International Journal of Pharma and Bio Sciences. 5, 2, p. P35-P42

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Citations (Scopus)
7 Citations (Scopus)

Synthesis and in vitro cholesteryl ester transfer protein inhibitory activity of novel esters of 2, 10-dichloro-12H-dibenzo [d,g] 1,3-dioxocin-6-carboxylic acid

Talluri, S., Kini, S. G., Kandale, A., Kumar, G. & Ohlyan, R., 2014, In : Medicinal Chemistry Research. 23, 10, p. 4491-4499 9 p.

Research output: Contribution to journalArticle

2013

Antioxidant activity of novel coumarin substituted benzothiazole derivatives

Choudhary, S., Kini, S. G. & Mubeen, M., 2013, In : Der Pharma Chemica. 5, 4, p. 213-222 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Cytotoxicity studies of microwave assisted natural product extracts in hela and MCF-7 cell lines

Dhanya, S., Kumar, N. V. A., Nayak, A. S., Raj, U. S., Prabhu, D. & Ravikiran, 2013, In : International Journal of Medicinal and Aromatic Plants. 3, 1, p. 27-31 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Development and validation of a new reversed-phase HPLC method for the determination of ezetimibe in pharmaceutical dosage forms

Panjwani, G., Shetty, R., Shenoy, G. & Dhamecha, D., 01-01-2013, In : Indian Journal of Pharmaceutical Education and Research. 47, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)

Microbial biotransformation-A novel approach for modification on coumarin substrates

Nigam, S., Rao, J. V. & Jayashree, B. S., 2013, In : Indian Journal of Biotechnology. 12, 3, p. 379-385 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Novel intervention to improve adherence to medication in diabetic patients: Formulation and evaluation of Metformin HCL novel dosage form

Kandi, M., Sivasai, G., Rathnanand, M., Sreenivasa Reddy, M. & Vijaya Bhasker, K., 2013, In : International Journal of Pharmacy and Pharmaceutical Sciences. 5, SUPPL 3, p. 587-592 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory, anticancer agents: Design, synthesis and biological screening

Suthar, S. K., Jaiswal, V., Lohan, S., Bansal, S., Chaudhary, A., Tiwari, A., Alex, A. T. & Joseph, A., 2013, In : European Journal of Medicinal Chemistry. 63, p. 589-602 14 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Preparation and characterisation of fluconazole vaginal films for the treatment of vaginal Candidiasis

Kumar, L., Reddy, M. S., Shirodkar, R. K., Pai, G. K., Krishna, V. T. & Verma, R., 2013, In : Indian Journal of Pharmaceutical Sciences. 75, 5, p. 585-590 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
1 Citation (Scopus)

Studies of corrosion of aluminium and 6063 aluminium alloy in phosphoric acid medium

Prabhu, D. & Padmalatha, 2013, In : International Journal of ChemTech Research. 5, 6, p. 2690-2705 16 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Synthesis, characterisation & useful therapeutic activity of novel 2-quinolone derivatives

Jayashree, B. S., Sharma, N. & Nigam, S., 01-12-2013, In : Indian Drugs. 50, 12, p. 41-46 6 p.

Research output: Contribution to journalArticle

Synthesis, in vitro anticancer and antioxidant activity of thiadiazole substituted thiazolidin-4-ones

Joseph, A., Shah, C. S., Kumar, S. S., Alex, A. T., Maliyakkal, N., Moorkoth, S. & Mathew, J. E., 01-09-2013, In : Acta Pharmaceutica. 63, 3, p. 397-408 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Synthesis and biological evaluation of novel triazolo-thiadiazole derivatives

Reddy, A., Kini, S. G. & Mubeen, M., 2013, In : Der Pharma Chemica. 5, 6, p. 259-272 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis and characterisation of novel 2,4-diphenyloxazole derivatives and evaluation of their in vitro antioxidant and anticancer activity

Mathew, J. A., Divya, G., Vachala, S. D., Mathew, J. A. & Jeyaprakash, R. S., 2013, In : Journal of Pharmacy Research. 6, 1, p. 210-213 4 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of a series of novel imidazolidinone analogues of 6-aminoflavone as anticancer and anti-inflammatory agents

Moorkoth, S., Srinivasan, K. K., Gopalan Kutty, N., Joseph, A. & Naseer, M., 2013, In : Medicinal Chemistry Research. 22, 10, p. 5066-5075 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

Antiglycation and anticancer activity of some newer synthetic flavones

Jayashree, B. S., Chaturvedi, P., Venkatachalam, H., Chaudary, P. V. R. & Nayak, Y., 2012, In : Der Pharma Chemica. 4, 4, p. 1626-1630 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Copolymerization of N-Vinyl pyrrolidone with methyl methacrylate by Ti(III)-DMG redox initiator

Parambil, A. M., Puttaiahgowda, Y. M. & Shankarappa, P., 06-2012, In : Turkish Journal of Chemistry. 36, 3, p. 397-409 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Effect of ethanol extract of Sphaeranthus indicus on cisplatin-induced nephrotoxicity in rats

Mathew, J. E., Joseph, A., Srinivasan, K., Dinakaran, S. V., Mantri, A. & Movaliya, V., 2012, In : Natural Product Research. 26, 10, p. 933-938 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In : Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Superbug NDM-1: A global health problem

Suthar, S. K., Joseph, A., Lohan, S. & Alex, A. T., 2012, In : Der Pharmacia Lettre. 4, 4, p. 1183-1187 5 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of novel pyrimidine-2(1H)-ones/thiones as potent anti-inflammatory and anticancer agents

Dinakaran, V. S., Jacob, D. & Mathew, J. E., 2012, In : Medicinal Chemistry Research. 21, 11, p. 3598-3606 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Synthesis of 3-methylflavones and their antioxidant and antibacterial activities

Jayashree, B. S., Alam, A., Nayak, Y. & Vijay Kumar, D., 08-2012, In : Medicinal Chemistry Research. 21, 8, p. 1991-1996 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2011

1-(2-Hy-droxy-4-methoxyphenyl)-3-(4-methylphenyl)prop-2-en-1-one

Thippeswamy, G. B., Vijay Kumar, D., Jayashree, B. S., Sridhar, M. A. & Shashidhara Prasad, J., 2011, In : Acta Crystallographica Section E: Structure Reports Online. 67, 4

Research output: Contribution to journalArticle

2 Citations (Scopus)

1-(2-Hy-droxy-5-methyl-phen-yl)-3-(2-methyl-phen-yl)prop-2-en-1-one

Kumar, D. V., Thippeswamy, G. B., Jayashree, B. S. & Sridhar, M. A., 2011, In : Acta Crystallographica Section E: Structure Reports Online. 67, 6

Research output: Contribution to journalArticle

1 Citation (Scopus)

Anti-inflammatory, antipruritic and mast cell stabilizing activity of Aristolochia indica

Mathew, J. E., Kaitheri, S. K., Dinakaranvachala, S. & Jose, M., 01-09-2011, In : Iranian Journal of Basic Medical Sciences. 14, 5, p. 422-427 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Antimicrobial, antioxidant and in vitro anti-inflammatory activity and phytochemical screening of water extract of wedelia trilobata (L.) hitchc

Govindappa, M., Naga Sravya, S., Poojashri, M. N., Sadananda, T. S., Chandrappa, C. P., Santoyo, G., Sharanappa, P. & Anil Kumar, N. V., 30-10-2011, In : Journal of Medicinal Plant Research. 5, 24, p. 5718-5729 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Antiulcer activity of leaf extract of lawsonia inermis in albino rats

Goli, V., Macharla, S. P., Vijaya Bhasker, K., Gowrishankar, N. L., Bhaskar, J. & Dhanalakshmi, C., 01-09-2011, In : Research Journal of Pharmacy and Technology. 4, 9, p. 1436-1438 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)