Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal

  • India

Research Output 1991 2019

2019
Carbapenems
Powders
Injections
meropenem
Nursing Staff

Active Targeting of Drugs and Bioactive Molecules via Oral Administration by Ligand-Conjugated Lipidic Nanocarriers: Recent Advances

Shreya, A. B., Raut, S. Y., Managuli, R. S., Udupa, N. & Mutalik, S., 01-01-2019, In : AAPS PharmSciTech. 20, 1, 15.

Research output: Contribution to journalReview article

Nanotechnology
Drug Delivery Systems
oral administration
Oral Administration
mouth
1 Citation (Scopus)

Computational modeling for formulation design

Mehta, C. H., Narayan, R. & Nayak, U. Y., 01-03-2019, In : Drug Discovery Today. 24, 3, p. 781-788 8 p.

Research output: Contribution to journalReview article

Drug Stability
Excipients
Hydrodynamics
Mechanics
Pharmaceutical Preparations

Evaluation of penetration process into young and elderly skin using confocal Raman spectroscopy

dos Santos, L., Tippavajhala, V. K., Mendes, T. O., da Silva, M. G. P., Fávero, P. P., Téllez Soto, C. A. & Martin, A. A., 01-01-2019, In : Vibrational Spectroscopy. 100, p. 123-130 8 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Skin
alpha-Tocopherol
Derivatives
Vitamins
Nanocomposites
Diclofenac
Microspheres
Polymers
Pharmaceutical Preparations

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Biotin
Embryonic Development
Spermatozoa
Pentoxifylline
Fertilization
2018
5 Citations (Scopus)

Amino acid conjugated chitosan nanoparticles for the brain targeting of a model dipeptidyl peptidase-4 inhibitor

Fernandes, J., Ghate, M. V., Basu Mallik, S. & Lewis, S. A., 25-08-2018, In : International Journal of Pharmaceutics. 547, 1-2, p. 563-571 9 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Chitosan
Nanoparticles
Amino Acids
Brain
5 Citations (Scopus)
Nanocomposites
Oxides
Isotherms
Kinetics
Adsorption
Blister
Marketing
Tablets
Hardness
Acetaminophen

A review on approaches used to overcome problems associated with conventional dosage forms of H2 antagonist

Tunge, R., Rathnanand, M., Fernandes, G. & Sharma, K., 01-04-2018, In : Journal of Global Pharma Technology. 10, 4, p. 1-8 8 p.

Research output: Contribution to journalArticle

Dosage Forms
Histamine H2 Receptors
Acids
Stomach
Nizatidine

A review on manufacturing operations of solid dosage forms: Design and implementation on GMP systems in the manufacturing facility

Girish Pai, K., Kumar, T. C. S., Parida, D. P. & Joseph, A., 01-06-2018, In : Journal of Global Pharma Technology. 10, 6, p. 1-10 10 p.

Research output: Contribution to journalReview article

Dosage Forms
Quality Control
Licensure
Guidelines
Manufacturing and Industrial Facilities
1 Citation (Scopus)

A review on polymeric nanoparticles: A promising novel drug delivery system

Priya, J., Naha, A., Dhoot, A. S. & Xalxo, N., 01-04-2018, In : Journal of Global Pharma Technology. 10, 4, p. 10-17 8 p.

Research output: Contribution to journalReview article

Drug Delivery Systems
Nanoparticles
Antineoplastic Agents
Polymers
Vaccines
2 Citations (Scopus)

A Review on Solubility Enhancement of Carvedilol—a BCS Class II Drug

Fernandes, G. J., Kumar, L., Sharma, K., Tunge, R. & Rathnanand, M., 01-09-2018, In : Journal of Pharmaceutical Innovation. 13, 3, p. 197-212 16 p.

Research output: Contribution to journalReview article

Solubility
Pharmaceutical Preparations
Nanoparticles
Biological Availability
Dendrimers
6 Citations (Scopus)

Comparative study of transdermal drug delivery systems of resveratrol: High efficiency of deformable liposomes

Tosato, M. G., Maya Girón, J. V., Martin, A. A., Krishna Tippavajhala, V., Fernández Lorenzo de Mele, M. & Dicelio, L., 01-09-2018, In : Materials Science and Engineering C. 90, p. 356-364 9 p.

Research output: Contribution to journalArticle

Resveratrol
Liposomes
delivery
drugs
Encapsulation

Cost analysis and utilization of mechanical ventilators in intensive care units of south India

Rani, U., Naveen Kumar, P. & Naha, A., 01-04-2018, In : Pakistan Journal of Medical and Health Sciences. 12, 2, p. 950-951 2 p.

Research output: Contribution to journalArticle

Mechanical Ventilators
Intensive Care Units
India
Costs and Cost Analysis
Tertiary Healthcare
1 Citation (Scopus)

Delving deeper into dermal and transdermal drug delivery: Factors and mechanisms associated with nanocarrier-mediated strategies

Manikkath, J., Sumathy, T. K., Manikkath, A. & Mutalik, S., 01-01-2018, In : Current Pharmaceutical Design. 24, 27, p. 3210-3222 13 p.

Research output: Contribution to journalReview article

Skin
Pharmaceutical Preparations
Drug Administration Routes
Drug Carriers
Particle Size

Design, drug likeness and molecular docking of novel molecules for anti- tubercular activity

Kumar, L. & Verma, R., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 4, p. 759-767 9 p.

Research output: Contribution to journalArticle

flavone
Flavones
Drug Design
Software
Enoyl-CoA Hydratase

Development and validation of a UV spectroscopic method to estimate etoricoxib in bulk and tablet formulation

Manideep, G., Shane, N. L. J., Pai, G. & Sathyanarayana, M. B., 01-02-2018, In : Research Journal of Pharmacy and Technology. 11, 2, p. 758-760 3 p.

Research output: Contribution to journalArticle

etoricoxib
Tablets
Methanol
Cyclooxygenase 2 Inhibitors
Anti-Inflammatory Agents
Suppositories
Fluconazole
Candida
Vulvovaginal Candidiasis
Infection
6 Citations (Scopus)

Development of ritonavir solid lipid nanoparticles by Box Behnken design for intestinal lymphatic targeting

Kumar, S., Narayan, R., Ahammed, V., Nayak, Y., Naha, A. & Nayak, U. Y., 01-04-2018, In : Journal of Drug Delivery Science and Technology. 44, p. 181-189 9 p.

Research output: Contribution to journalArticle

Ritonavir
Nanoparticles
Lipids
Particle Size
Biological Availability

Development of thermoreversible in situ Nasal Gel using chitosan as a mucoadhesive agent for prophylaxis of migraine

Ghatwal, S., Harmalkar, D., Godinho, S., Kumar, L. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 12, p. 2365-2372 8 p.

Research output: Contribution to journalArticle

Flunarizine
Chitosan
Migraine Disorders
Nose
Poloxamer

Emerging novel nanopharmaceuticals for drug delivery

Wadhwa, A., Mathura, V. & Lewis, S. A., 01-07-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 7, p. 35-42 8 p.

Research output: Contribution to journalReview article

Nanotechnology
Nanofibers
Carbon Nanotubes
Drug Delivery Systems
Pharmaceutical Preparations
1 Citation (Scopus)
letrozole
Design of experiments
Research Design
Liquids
Flow rate
3 Citations (Scopus)
efavirenz
solubility
Solubility
preparation
dissolving
Drug Industry
Industry
Software
Education
Smartphone
1 Citation (Scopus)
beta-cyclodextrin
Computer Simulation
inclusions
prediction
predictions
2 Citations (Scopus)

In Vivo Determination of Moisturizers Efficacy on Human Skin Hydration by Confocal Raman Spectroscopy

Tippavajhala, V. K., Magrini, T. D., Matsuo, D. C., Silva, M. G. P., Favero, P. P., De Paula, L. R. & Martin, A. A., 01-10-2018, In : AAPS PharmSciTech. 19, 7, p. 3177-3186 10 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Raman Spectrum Analysis
skin (animal)
Skin
Dermatoglyphics
2 Citations (Scopus)

In Vivo Human Skin Penetration Study of Sunscreens by Confocal Raman Spectroscopy

Tippavajhala, V. K., de Oliveira Mendes, T. & Martin, A. A., 05-10-2018, In : AAPS PharmSciTech. p. 1-8 8 p.

Research output: Contribution to journalArticle

Sunscreening Agents
Raman spectroscopy
Raman Spectrum Analysis
skin (animal)
Skin
1 Citation (Scopus)

In vivo study of dermal collagen of striae distensae by confocal Raman spectroscopy

Lung, P. W., Tippavajhala, V. K., de Oliveira Mendes, T., Téllez-Soto, C. A., Schuck, D. C., Brohem, C. A., Lorencini, M. & Martin, A. A., 01-04-2018, In : Lasers in Medical Science. 33, 3, p. 609-617 9 p.

Research output: Contribution to journalArticle

Striae Distensae
Raman Spectrum Analysis
Collagen
Skin
Discriminant Analysis

Lacidipine porous tablets: Formulation and in vitro characterization

Estibeiro, A. L., Harmalkar, D., Godinho, S., Kumar, L. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 9, p. 1764-1771 8 p.

Research output: Contribution to journalArticle

Tablets
Solubility
Biological Availability
Buffers
Camphor
1 Citation (Scopus)

Liquisolid technique using tween 80 and sodium starch glycolate to enhance the solubility and dissolution rate of an antihypertensive drug

Naik, E., Harmalkar, D., Godinho, S., Kumar, L., Lewis, S. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 4, p. 717-726 10 p.

Research output: Contribution to journalArticle

Polysorbates
Solubility
Antihypertensive Agents
Tablets
Calcium Channel Blockers
2 Citations (Scopus)

Localized in situ nanoemulgel drug delivery system of quercetin for periodontitis: Development and computational simulations

Aithal, G. C., Nayak, U. Y., Mehta, C., Narayan, R., Gopalkrishna, P., Pandiyan, S. & Garg, S., 01-01-2018, In : Molecules. 23, 6, 1363.

Research output: Contribution to journalArticle

Periodontitis
Quercetin
Drug Delivery Systems
delivery
drugs
5 Citations (Scopus)

Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In : International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

Research output: Contribution to journalArticle

Chitosan
Nanoparticles
Pharmacodynamics
Pharmacokinetics
Pharmaceutical Preparations
18 Citations (Scopus)

Mesoporous silica nanoparticles: A comprehensive review on synthesis and recent advances

Narayan, R., Nayak, U. Y., Raichur, A. M. & Garg, S., 01-09-2018, In : Pharmaceutics. 10, 3, 118.

Research output: Contribution to journalReview article

Silicon Dioxide
Nanoparticles
Drug Carriers
Pharmaceutical Preparations
Patents

Mesoporous silica particles for dermal drug delivery: A review

Sanjay, C., Ghate, V. M. & Lewis, S. A., 01-01-2018, In : International Journal of Applied Pharmaceutics. 10, 6, p. 23-26 4 p.

Research output: Contribution to journalReview article

Silicon Dioxide
Skin
Pharmaceutical Preparations
Drug Stability
Subunit Vaccines

Nanocrystals: A newer technological advancement in drug delivery

Xalxo, N., Naha, A., Dhoot, A. & Priya, J., 01-04-2018, In : Research Journal of Pharmacy and Technology. 11, 4, p. 1685-1690 6 p.

Research output: Contribution to journalReview article

Nanoparticles
Solubility
Industry
Technology
Dosage Forms

Phase diagrams for three component mixtures in pharmaceuticals and its applications

Dhoot, A. S., Naha, A., Priya, J. & Xalxo, N., 01-04-2018, In : Journal of Young Pharmacists. 10, 2, p. 132-137 6 p.

Research output: Contribution to journalReview article

Drug Compounding
Emulsions
Dosage Forms
Surface-Active Agents
Pharmaceutical Preparations

Porous Oral Drug Delivery System: Tablets

Singh, S. Y., Verma, R. & Kumar, L., 01-09-2018, In : Pharmaceutical Chemistry Journal. 52, 6, p. 553-561 9 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Tablets
Pharmaceutical Preparations
Drug Compounding
Water

President’s emergency plan for AIDS relief

Jadeja, S., Pai, G., Bhat, K. & Sathyanarayana, M. B., 01-01-2018, In : Systematic Reviews in Pharmacy. 9, 1, p. 6-9 4 p.

Research output: Contribution to journalReview article

Acquired Immunodeficiency Syndrome
Emergencies
State Government
Developed Countries
Developing Countries

Rapidly dissolving lacidipine nanoparticle strips for transbuccal administration

Chandra, A., Chondkar, A. D., Shirodkar, R. & Lewis, S. A., 01-10-2018, In : Journal of Drug Delivery Science and Technology. 47, p. 259-267 9 p.

Research output: Contribution to journalArticle

Nanoparticles
Plasticizers
Mouth Mucosa
Particle Size
Sodium Dodecyl Sulfate
temozolomide
High Pressure Liquid Chromatography
Brain
formic acid
Pharmaceutical Preparations
1 Citation (Scopus)
gemcitabine
Iontophoresis
Skin
Pharmaceutical Preparations
HEPES

Strategies for improving the specificity of siRNAs for enhanced therapeutic potential

Gatta, A. K., Hariharapura, R. C., Udupa, N., Reddy, M. S. & Josyula, V. R., 03-08-2018, In : Expert Opinion on Drug Discovery. 13, 8, p. 709-725 17 p.

Research output: Contribution to journalReview article

Small Interfering RNA
RNA Interference
Therapeutics
Expert Testimony
Endocytosis
1 Citation (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

Sunscreening Agents
Nanoparticles
Skin
In Vitro Techniques
naringenin
5 Citations (Scopus)

Targeting the intestinal lymphatic system: a versatile path for enhanced oral bioavailability of drugs

Managuli, R. S., Raut, S. Y., Reddy, M. S. & Mutalik, S., 03-08-2018, In : Expert Opinion on Drug Delivery. 15, 8, p. 787-804 18 p.

Research output: Contribution to journalReview article

Lymphatic System
Biological Availability
Nanoparticles
Pharmaceutical Preparations
Peyer's Patches

Vaccines as a preventive modality for malaria: A review

Singh, A. K., Ghate, V. M. & Lewis, S. A., 01-07-2018, In : Asian Journal of Pharmaceutics. 12, 3, p. S873-S879

Research output: Contribution to journalReview article

Malaria
Vaccines
Parasitic Diseases
Routine Diagnostic Tests
Pregnancy
2017
2 Citations (Scopus)

A comparative release study of curcumin and diclofenac sodium from genipin cross-linked composite hydrogel

Dathathri, E., Nayak, R. R., Philip, J. A., Thakur, G. & Koteshwara, K. B., 06-03-2017, 2016 IEEE Students' Technology Symposium, TechSym 2016. Institute of Electrical and Electronics Engineers Inc., p. 106-109 4 p. 7872664

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrogel
Hydrogels
Sodium
swelling
Composite
4 Citations (Scopus)

A novel long-acting biodegradable depot formulation of anastrozole for breast cancer therapy

Shavi, G. V., Nayak, U. Y., Reddy, M. S., Ginjupalli, K., Deshpande, P. B., Averineni, R. K., Udupa, N., Sadhu, S. S., Danilenkoff, C. & Raghavendra, R., 01-06-2017, In : Materials Science and Engineering C. 75, p. 535-544 10 p.

Research output: Contribution to journalArticle

Microspheres
breast
therapy
drugs
cancer

Antimicrobial resistance: A cause for concern

Shailendrakumar, A. M. & Lewis, S. A., 01-08-2017, In : Pharma Times. 49, 8, p. 14-20 7 p.

Research output: Contribution to journalReview article

Drug Resistance
Anti-Bacterial Agents
Microbial Drug Resistance
Health Care Costs
Bacteria

An update on solubility enhancement methods for BCS class -II drugs

Naaz, S. & Tippavajhala, V. K., 01-09-2017, In : Journal of Global Pharma Technology. 9, 9, p. 48-57 10 p.

Research output: Contribution to journalReview article

Solubility
Pharmaceutical Preparations
Research
Therapeutics