Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal

  • India

Research Output 1991 2019

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Article
2019
Carbapenems
Powders
Injections
meropenem
Nursing Staff

Evaluation of penetration process into young and elderly skin using confocal Raman spectroscopy

dos Santos, L., Tippavajhala, V. K., Mendes, T. O., da Silva, M. G. P., Fávero, P. P., Téllez Soto, C. A. & Martin, A. A., 01-01-2019, In : Vibrational Spectroscopy. 100, p. 123-130 8 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Skin
alpha-Tocopherol
Derivatives
Vitamins
Nanocomposites
Diclofenac
Microspheres
Polymers
Pharmaceutical Preparations

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Biotin
Embryonic Development
Spermatozoa
Pentoxifylline
Fertilization
2018
5 Citations (Scopus)

Amino acid conjugated chitosan nanoparticles for the brain targeting of a model dipeptidyl peptidase-4 inhibitor

Fernandes, J., Ghate, M. V., Basu Mallik, S. & Lewis, S. A., 25-08-2018, In : International Journal of Pharmaceutics. 547, 1-2, p. 563-571 9 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Chitosan
Nanoparticles
Amino Acids
Brain
5 Citations (Scopus)
Nanocomposites
Oxides
Isotherms
Kinetics
Adsorption
Blister
Marketing
Tablets
Hardness
Acetaminophen

A review on approaches used to overcome problems associated with conventional dosage forms of H2 antagonist

Tunge, R., Rathnanand, M., Fernandes, G. & Sharma, K., 01-04-2018, In : Journal of Global Pharma Technology. 10, 4, p. 1-8 8 p.

Research output: Contribution to journalArticle

Dosage Forms
Histamine H2 Receptors
Acids
Stomach
Nizatidine
6 Citations (Scopus)

Comparative study of transdermal drug delivery systems of resveratrol: High efficiency of deformable liposomes

Tosato, M. G., Maya Girón, J. V., Martin, A. A., Krishna Tippavajhala, V., Fernández Lorenzo de Mele, M. & Dicelio, L., 01-09-2018, In : Materials Science and Engineering C. 90, p. 356-364 9 p.

Research output: Contribution to journalArticle

Resveratrol
Liposomes
delivery
drugs
Encapsulation

Cost analysis and utilization of mechanical ventilators in intensive care units of south India

Rani, U., Naveen Kumar, P. & Naha, A., 01-04-2018, In : Pakistan Journal of Medical and Health Sciences. 12, 2, p. 950-951 2 p.

Research output: Contribution to journalArticle

Mechanical Ventilators
Intensive Care Units
India
Costs and Cost Analysis
Tertiary Healthcare

Design, drug likeness and molecular docking of novel molecules for anti- tubercular activity

Kumar, L. & Verma, R., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 4, p. 759-767 9 p.

Research output: Contribution to journalArticle

flavone
Flavones
Drug Design
Software
Enoyl-CoA Hydratase

Development and validation of a UV spectroscopic method to estimate etoricoxib in bulk and tablet formulation

Manideep, G., Shane, N. L. J., Pai, G. & Sathyanarayana, M. B., 01-02-2018, In : Research Journal of Pharmacy and Technology. 11, 2, p. 758-760 3 p.

Research output: Contribution to journalArticle

etoricoxib
Tablets
Methanol
Cyclooxygenase 2 Inhibitors
Anti-Inflammatory Agents
Suppositories
Fluconazole
Candida
Vulvovaginal Candidiasis
Infection
6 Citations (Scopus)

Development of ritonavir solid lipid nanoparticles by Box Behnken design for intestinal lymphatic targeting

Kumar, S., Narayan, R., Ahammed, V., Nayak, Y., Naha, A. & Nayak, U. Y., 01-04-2018, In : Journal of Drug Delivery Science and Technology. 44, p. 181-189 9 p.

Research output: Contribution to journalArticle

Ritonavir
Nanoparticles
Lipids
Particle Size
Biological Availability

Development of thermoreversible in situ Nasal Gel using chitosan as a mucoadhesive agent for prophylaxis of migraine

Ghatwal, S., Harmalkar, D., Godinho, S., Kumar, L. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 12, p. 2365-2372 8 p.

Research output: Contribution to journalArticle

Flunarizine
Chitosan
Migraine Disorders
Nose
Poloxamer
1 Citation (Scopus)
letrozole
Design of experiments
Research Design
Liquids
Flow rate
3 Citations (Scopus)
efavirenz
solubility
Solubility
preparation
dissolving
Drug Industry
Industry
Software
Education
Smartphone
1 Citation (Scopus)
beta-cyclodextrin
Computer Simulation
inclusions
prediction
predictions
2 Citations (Scopus)

In Vivo Determination of Moisturizers Efficacy on Human Skin Hydration by Confocal Raman Spectroscopy

Tippavajhala, V. K., Magrini, T. D., Matsuo, D. C., Silva, M. G. P., Favero, P. P., De Paula, L. R. & Martin, A. A., 01-10-2018, In : AAPS PharmSciTech. 19, 7, p. 3177-3186 10 p.

Research output: Contribution to journalArticle

Raman spectroscopy
Raman Spectrum Analysis
skin (animal)
Skin
Dermatoglyphics
2 Citations (Scopus)

In Vivo Human Skin Penetration Study of Sunscreens by Confocal Raman Spectroscopy

Tippavajhala, V. K., de Oliveira Mendes, T. & Martin, A. A., 05-10-2018, In : AAPS PharmSciTech. p. 1-8 8 p.

Research output: Contribution to journalArticle

Sunscreening Agents
Raman spectroscopy
Raman Spectrum Analysis
skin (animal)
Skin
1 Citation (Scopus)

In vivo study of dermal collagen of striae distensae by confocal Raman spectroscopy

Lung, P. W., Tippavajhala, V. K., de Oliveira Mendes, T., Téllez-Soto, C. A., Schuck, D. C., Brohem, C. A., Lorencini, M. & Martin, A. A., 01-04-2018, In : Lasers in Medical Science. 33, 3, p. 609-617 9 p.

Research output: Contribution to journalArticle

Striae Distensae
Raman Spectrum Analysis
Collagen
Skin
Discriminant Analysis

Lacidipine porous tablets: Formulation and in vitro characterization

Estibeiro, A. L., Harmalkar, D., Godinho, S., Kumar, L. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 9, p. 1764-1771 8 p.

Research output: Contribution to journalArticle

Tablets
Solubility
Biological Availability
Buffers
Camphor
1 Citation (Scopus)

Liquisolid technique using tween 80 and sodium starch glycolate to enhance the solubility and dissolution rate of an antihypertensive drug

Naik, E., Harmalkar, D., Godinho, S., Kumar, L., Lewis, S. & Shirodkar, R. K., 01-01-2018, In : Latin American Journal of Pharmacy. 37, 4, p. 717-726 10 p.

Research output: Contribution to journalArticle

Polysorbates
Solubility
Antihypertensive Agents
Tablets
Calcium Channel Blockers
2 Citations (Scopus)

Localized in situ nanoemulgel drug delivery system of quercetin for periodontitis: Development and computational simulations

Aithal, G. C., Nayak, U. Y., Mehta, C., Narayan, R., Gopalkrishna, P., Pandiyan, S. & Garg, S., 01-01-2018, In : Molecules. 23, 6, 1363.

Research output: Contribution to journalArticle

Periodontitis
Quercetin
Drug Delivery Systems
delivery
drugs
5 Citations (Scopus)

Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In : International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

Research output: Contribution to journalArticle

Chitosan
Nanoparticles
Pharmacodynamics
Pharmacokinetics
Pharmaceutical Preparations

Porous Oral Drug Delivery System: Tablets

Singh, S. Y., Verma, R. & Kumar, L., 01-09-2018, In : Pharmaceutical Chemistry Journal. 52, 6, p. 553-561 9 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Tablets
Pharmaceutical Preparations
Drug Compounding
Water

Rapidly dissolving lacidipine nanoparticle strips for transbuccal administration

Chandra, A., Chondkar, A. D., Shirodkar, R. & Lewis, S. A., 01-10-2018, In : Journal of Drug Delivery Science and Technology. 47, p. 259-267 9 p.

Research output: Contribution to journalArticle

Nanoparticles
Plasticizers
Mouth Mucosa
Particle Size
Sodium Dodecyl Sulfate
temozolomide
High Pressure Liquid Chromatography
Brain
formic acid
Pharmaceutical Preparations
1 Citation (Scopus)
gemcitabine
Iontophoresis
Skin
Pharmaceutical Preparations
HEPES
1 Citation (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

Sunscreening Agents
Nanoparticles
Skin
In Vitro Techniques
naringenin
2017
4 Citations (Scopus)

A novel long-acting biodegradable depot formulation of anastrozole for breast cancer therapy

Shavi, G. V., Nayak, U. Y., Reddy, M. S., Ginjupalli, K., Deshpande, P. B., Averineni, R. K., Udupa, N., Sadhu, S. S., Danilenkoff, C. & Raghavendra, R., 01-06-2017, In : Materials Science and Engineering C. 75, p. 535-544 10 p.

Research output: Contribution to journalArticle

Microspheres
breast
therapy
drugs
cancer
4 Citations (Scopus)

A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: Tumor-specific homing directed by nestin

Prabhu, S., Goda, J. S., Mutalik, S., Mohanty, B. S., Chaudhari, P., Rai, S., Udupa, N. & Rao, B. S. S., 14-08-2017, In : Nanoscale. 9, 30, p. 10919-10932 14 p.

Research output: Contribution to journalArticle

temozolomide
Nestin
Heterografts
Tumors
Nanocomposites
13 Citations (Scopus)
Strategic materials
Pharmacokinetics
Polyvinyl alcohols
Polydispersity
Zeta potential
6 Citations (Scopus)

A top-down technique to improve the solubility and bioavailability of aceclofenac: In vitro and in vivo studies

Narayan, R., Pednekar, A., Bhuyan, D., Gowda, C., Koteshwara, K. B. & Nayak, U. Y., 11-07-2017, In : International Journal of Nanomedicine. 12, p. 4921-4935 15 p.

Research output: Contribution to journalArticle

Solubility
Nanocrystals
Biological Availability
Nanoparticles
Particle Size
3 Citations (Scopus)
Chitosan
Scaffolds
Wound Healing
Curcumin
Electron Scanning Microscopy
1 Citation (Scopus)

Biodegradable composite scaffolds of poly(lactic-co-glycolic acid) 85: 15 and nano-hydroxyapatite with acidic microclimate controlling additive

Ginjupalli, K., Averineni, R. K., Shavi, G. V., Armugam, K., Bhat, M., Udupa, N. & Meka, S. R., 01-06-2017, In : Polymer Composites. 38, 6, p. 1175-1182 8 p.

Research output: Contribution to journalArticle

Durapatite
Hydroxyapatite
Scaffolds
Magnesium
Carbonates

Characterization of the Phenolic Compound, Gallic Acid from Sansevieria roxburghiana Schult and Schult. f. Rhizomes and Antioxidant and Cytotoxic Activities Evaluation

Maheshwari, R., Shreedhara, C. S., Polu, P. R., Managuli, R. S., Xavier, S. K., Lobo, R., Setty, M. & Mutalik, S., 11-10-2017, In : Pharmacognosy Magazine. 13, 51, p. S693-S699

Research output: Contribution to journalArticle

Sansevieria
Gallic Acid
Rhizome
Antioxidants
lissamine rhodamine B
Valsartan
Solubility
Succinic Acid
Pharmaceutical Preparations
Fourier Transform Infrared Spectroscopy
4 Citations (Scopus)

Development and in vivo evaluation of functionalized ritonavir proliposomes for lymphatic targeting

Ahammed, V., Narayan, R., Paul, J., Nayak, Y., Roy, B., Shavi, G. V. & Nayak, U. Y., 15-08-2017, In : Life Sciences. 183, p. 11-20 10 p.

Research output: Contribution to journalArticle

Ritonavir
Biotin
Particle Size
Liposomes
Biological Availability
Nicardipine
Nanoparticles
High Pressure Liquid Chromatography
Lipids
formic acid

Development of polyvinlyl alcohol-chitosan-hydroxypropylmethylcellulose based composite films for controlled drug delivery

Gopalakrishnan, S., Dathathri, E., Thakur, G. & Koteshwara, K. B., 01-01-2017, In : Trends in Biomaterials and Artificial Organs. 31, 3, p. 97-101 5 p.

Research output: Contribution to journalArticle

Polyvinyl Alcohol
Chitosan
Alcohols
Wound Healing
Polymers
3 Citations (Scopus)
Nanocomposites
Heterografts
Toxicity
Cells
Breast Neoplasms
1 Citation (Scopus)
Solubility
Pharmaceutical Preparations
Fourier Transform Infrared Spectroscopy
Crystallization
Hydrogen
1 Citation (Scopus)

Formulation and evaluation of irbesartan nanosuspension for dissolution enhancement

Khushboo, M., Naik, K., Vasanthi, Menezes, A., Naha, A., Koteshwara, K. B. & Girish Pai, K., 01-09-2017, In : Research Journal of Pharmacy and Technology. 10, 9, p. 3043-3048 6 p.

Research output: Contribution to journalArticle

irbesartan
Sonication
Excipients
Pharmaceutical Preparations
Buffers
1 Citation (Scopus)
Haploidy
Ammonia
Embryonic Structures
Blastocyst
Parthenogenesis
12 Citations (Scopus)

Inclusion complexation of etodolac with hydroxypropyl-beta-cyclodextrin and auxiliary agents: Formulation characterization and molecular modeling studies

Sherje, A. P., Kulkarni, V., Murahari, M., Nayak, U. Y., Bhat, P., Suvarna, V. & Dravyakar, B., 2017, In : Molecular Pharmaceutics. 14, 4, p. 1231-1242 12 p.

Research output: Contribution to journalArticle

Etodolac
Solubility
Colorimetry
X-Ray Diffraction
Powders
3 Citations (Scopus)
Propolis
Mitomycin
DNA Damage
Antioxidants
Fertility Preservation
20 Citations (Scopus)

Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen

Manikkath, J., Hegde, A. R., Kalthur, G., Parekh, H. S. & Mutalik, S., 15-04-2017, In : International Journal of Pharmaceutics. 521, 1-2, p. 110-119 10 p.

Research output: Contribution to journalArticle

Ketoprofen
Dendrimers
Peptides
Pharmaceutical Preparations
Arginine
1 Citation (Scopus)
Inositol
Liposomes
Glycerol
Oocytes
Blastocyst