Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Organization profile

Organisation profile

Department of Pharmacology at Manipal College of Pharmaceutical Sciences has top-drawer facilities for research in cancer, metabolic disorders, diabetes, inflammatory diseases, chemoprevention, tissue repair, and neuropharmacology. Faculty members, research scholars, and postgraduate students are actively involved in research projects. BPharm students in their fourth year are also nurtured for taking up short-term projects. Ample research proposals have received funding from government agencies, namely AICTE, DBT, and DST. The department has developed tie-up with several industries like Enovate Bio Life, Mumbai, Indus Biotech, Pune and Cholayil Private Limited, Chennai to undertake work on their drugs and formulations. Full-fledged cell culture lab (with Western blotting, flow cytometry, cell analyzer) caters to research needs. Technical skills in instrument handling (HPLC, electrophoresis, fluorescent imaging) is provided at the department.

Fruitful collaborations are established with Molecular Neurotherapy and Imaging Laboratory, Radiology and Neurology at Massachusetts General Hospital, Boston, USA, University of California, Irwin, USA and Griffith University, Australia.

Highlights of Notable contributions:

DHPO (2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate) a potent activator of AMPK was developed in Department of Pharmacology. The molecule is currently marked by Merck Life Science Pvt. Ltd., as an AMPK activator for investigational purpose.

Investigation has been carried out to establish the effectiveness of Indian receipe "Sambar" against animal models of cancer. The study highlights the importance of spices that are constant factor in Indian diet which are effective against disorders of inflammatroy origin. The work has won accolades from global research community.

Fingerprint Dive into the research topics where Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Antioxidants Medicine & Life Sciences
Rats Chemical Compounds
Wistar Rats Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Derivatives Chemical Compounds
Inhibitory Concentration 50 Medicine & Life Sciences
Flavonoids Medicine & Life Sciences
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1991 2019

Annona muricata fruit extract protects against diethylnitrosamine-induced hepatocellular cancer in rats

Thomas, S., Paul, J., Shrungeswara, A., Biswas, S., Shah, A., Subraya, C. & Nayak, Y., 01-06-2019, In : Asian Pacific Journal of Tropical Medicine. 12, 6, p. 272-282 11 p.

Research output: Contribution to journalArticle

Annona
Diethylnitrosamine
Liver Neoplasms
Fruit
Chloroform
Caesalpinia
Hep G2 Cells
Acetaminophen
Glutathione
Genes

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Illness Behavior
Cannabinoid Receptors
Lipopolysaccharides
Oxidative Stress
Tumor Necrosis Factor-alpha

Projects 2013 2022

Prizes

AICTE Sponsored Faculty Development Program for two weeks

Yogendra Nayak (Recipient), 19-08-2019

Prize: Other distinction

File
moral philosophy
memorial
pharmaceutical
India
school
education

Activities 2017 2019

  • 4 Publication peer-review
  • 2 Editorial activity
  • 1 Participation in workshop, seminar, course
  • 1 Invited talk

AICTE Sponsored Faculty Development Program

Yogendra Nayak (Participant)
19-08-2019

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Scientific Reports (Journal)

Yogendra Nayak (Member of editorial board)
2019

Activity: Publication peer-review and editorial work typesEditorial activity

Journal of Medicinal Chemistry (Journal)

Yogendra Nayak (Reviewer)
2018

Activity: Publication peer-review and editorial work typesPublication peer-review