Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

2020

Aberrant canonical Wnt signaling: Phytochemical based modulation

Manandhar, S., Kabekkodu, S. P. & Pai, K. S. R., 09-2020, In : Phytomedicine. 76, 153243.

Research output: Contribution to journalReview article

A Review on Anticancer Potentials of Benzothiazole Derivatives

Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In : Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 2020, (Accepted/In press) In : Andrologia.

Research output: Contribution to journalArticle

Combination therapy and nanoparticulate systems: Smart approaches for the effective treatment of breast cancer

Gadag, S., Sinha, S., Nayak, Y., Garg, S. & Nayak, U. Y., 06-2020, In : Pharmaceutics. 12, 6, p. 1-37 37 p., 524.

Research output: Contribution to journalReview article

Open Access
Open Access

COVID-19: Emergence, Spread, Possible Treatments, and Global Burden

Keni, R., Alexander, A., Nayak, P. G., Mudgal, J. & Nandakumar, K., 28-05-2020, In : Frontiers in Public Health. 8, 216.

Research output: Contribution to journalReview article

Efficacy and safety of inhalation budesonide in the treatment of pediatric asthma in the emergency department: a systematic review and meta-analysis

Viswanatha, G. L., Shylaja, H., Nandakumar, K., Venkataranganna, M. V. & Prasad, N. B. L., 01-01-2020, (Accepted/In press) In : Pharmacological Reports.

Research output: Contribution to journalReview article

Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In : European Journal of Medicinal Chemistry. 201, 112335.

Research output: Contribution to journalArticle

Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In : 3 Biotech. 10, 4, 149.

Research output: Contribution to journalArticle

Structural Proteins in Severe Acute Respiratory Syndrome Coronavirus-2

Satarker, S. & Nampoothiri, M., 01-01-2020, (Accepted/In press) In : Archives of Medical Research.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

Thirupataiah, B., Reddy, G. S., Ghule, S. S., Kumar, J. S., Mounika, G., Hossain, K. A., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 04-2020, In : Bioorganic Chemistry. 97, 103691.

Research output: Contribution to journalArticle

Virgin coconut oil ameliorates colchicine induced cognitive dysfunction- A preclinical study

John, J., Sapa, N. K. & Shenoy, R. R., 03-2020, In : Pharmaceutical Sciences. 26, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
2019

Annona muricata fruit extract protects against diethylnitrosamine-induced hepatocellular cancer in rats

Thomas, S., Paul, J., Shrungeswara, A., Biswas, S., Shah, A., Subraya, C. & Nayak, Y., 01-06-2019, In : Asian Pacific Journal of Tropical Medicine. 12, 6, p. 272-282 11 p.

Research output: Contribution to journalArticle

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In : Biomedical Reports. 11, 2, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2 Citations (Scopus)

Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In : Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Histogenesis and Histomorphometric study of Human Fetal Small Intestine

Salva, M. N., Gupta, C., Pandey, A. K., Kumar, N., Kotian, S. R. & Kalthur, S. G., 01-11-2019, In : Ethiopian journal of health sciences. 29, 6, p. 689-696 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In : European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Influence of traditional medicines on the activity of keratinocytes in wound healing: An in-vitro study

Kotian, S. R., Bhat, K. M. R., Padma, D. & Pai, K. S. R., 01-01-2019, In : Anatomy and Cell Biology. 52, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

Medhya rasayana restores memory function against doxorubicin-induced cognitive decline: Possibly by its neuroprotective effect

Gourishetti, K., Ghetia, S., Jacob, L., Mallik, S. B., Nayak, P. G., Kishore, A., Nandakumar, K., Alnaseer, S. M. & Hussain, S. M., 01-04-2019, In : Indian Journal of Pharmaceutical Education and Research. 53, 2, p. S104-S111

Research output: Contribution to journalArticle

Open Access

Neprilysin, the kidney brush border neutral proteinase: a possible potential target for ischemic renal injury

Sankhe, R., Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2019, (Accepted/In press) In : Toxicology Mechanisms and Methods.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Poly(N,N-diethyl acrylamide)/functionalized graphene quantum dots hydrogels loaded with doxorubicin as a nano-drug carrier for metastatic lung cancer in mice

Havanur, S., Batish, I., Cheruku, S. P., Gourishetti, K., JagadeeshBabu, P. E. & Kumar, N., 01-12-2019, In : Materials Science and Engineering C. 105, 110094.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In : Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

Research output: Contribution to journalArticle

Sesamol and health - A comprehensive review

Shah, A., Lobo, R., Krishnadas, N. & Surubhotla, R., 01-04-2019, In : Indian Journal of Pharmaceutical Education and Research. 53, 2, p. S28-S42

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

Targeting HIV-TB coinfection by developing novel piperidin-4-substituted imines: Design, synthesis, in vitro and in silico studies

Kumar, A., Revathi, R., Sriram, D., Curreli, F., Debnath, A. K., Pai, K. S. & Kini, S. G., 01-06-2019, In : Archiv der Pharmazie. 352, 6, 1800358.

Research output: Contribution to journalArticle

Terminalia tomentosa bark ameliorates inflammation and arthritis in carrageenan induced inflammatory model and freund's adjuvant-induced arthritis model in rats

Jitta, S. R., Daram, P., Gourishetti, K., Misra, C. S., Polu, P. R., Shah, A., Shreedhara, C. S., Nampoothiri, M. & Lobo, R., 01-01-2019, In : Journal of Toxicology. 2019, 7898914.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy

Kanwal, A., Pillai, V. B., Samant, S., Gupta, M. & Gupta, M. P., 12-07-2019, In : FASEB Journal. p. fj201900767R

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Amelioration of arsenic-induced oxidative stress in CHO cells by Ixora coccinea flower extract

Salmataj, S. A., Kamath, S. U., Murty, V. R. & Pai, S. R., 01-10-2018, In : 3 Biotech. 8, 10, 446.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An Appraisal of Pumpkin Seed Extract in 1, 2-Dimethylhydrazine Induced Colon Cancer in Wistar Rats

Chari, K. Y., Polu, P. R. & Shenoy, R. R., 01-01-2018, In : Journal of Toxicology. 2018, 6086490.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 03-10-2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antimicrobial activity of aqueous and ethanolic leaf extracts of anacardium occidentale

Shobha, K. L., Rao, A. S., Pai, K. S. R. & Bhat, S., 01-12-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 12, p. 474-476 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1 Citation (Scopus)

Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In : Cytotechnology. p. 1-15 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In : Andrologia. 50, 7, e13037.

Research output: Contribution to journalArticle

2 Citations (Scopus)