Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

2021

Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico study

Sankhe, R., Rathi, E., Manandhar, S., Kumar, A., Pai, S. R. K., Kini, S. G. & Kishore, A., 15-01-2021, In : Journal of Molecular Structure. 1224, 129073.

Research output: Contribution to journalArticle

Open Access
2020

Aberrant canonical Wnt signaling: Phytochemical based modulation

Manandhar, S., Kabekkodu, S. P. & Pai, K. S. R., 09-2020, In : Phytomedicine. 76, 153243.

Research output: Contribution to journalReview article

Advances in targeting EGFR allosteric site as anti-NSCLC therapy to overcome the drug resistance

Maity, S., Pai, K. S. R. & Nayak, Y., 2020, (Accepted/In press) In : Pharmacological Reports.

Research output: Contribution to journalReview article

Open Access

An appraisal of current pharmacological perspectives of sesamol: A review

Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In : Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

Research output: Contribution to journalReview article

An overview on chemotherapy-induced cognitive impairment and potential role of antidepressants

Das, A., Ranadive, N., Kinra, M., Nampoothiri, M., Arora, D. & Mudgal, J., 2020, In : Current Neuropharmacology. 18, 9, p. 838-851 14 p.

Research output: Contribution to journalReview article

A Review on Anticancer Potentials of Benzothiazole Derivatives

Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In : Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 2020, (Accepted/In press) In : Andrologia.

Research output: Contribution to journalArticle

Botrops derived hemocoagulase formulation a probable agent for diabetic wound healing

Keni, R., Gourishetti, K., Kinra, M., Nayak, P. G., Shenoy, R., Nandakumar, K., Jagdale, R. N., Raghavendra, K. V. & Ahmed, S. M., 01-10-2020, In : 3 Biotech. 10, 10, 443.

Research output: Contribution to journalArticle

Open Access

Combination therapy and nanoparticulate systems: Smart approaches for the effective treatment of breast cancer

Gadag, S., Sinha, S., Nayak, Y., Garg, S. & Nayak, U. Y., 06-2020, In : Pharmaceutics. 12, 6, p. 1-37 37 p., 524.

Research output: Contribution to journalReview article

Open Access
Open Access
Open Access

COVID-19: Emergence, Spread, Possible Treatments, and Global Burden

Keni, R., Alexander, A., Nayak, P. G., Mudgal, J. & Nandakumar, K., 28-05-2020, In : Frontiers in Public Health. 8, 216.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In : 3 Biotech. 10, 10, 438.

Research output: Contribution to journalArticle

Open Access

Efficacy and safety of inhalation budesonide in the treatment of pediatric asthma in the emergency department: a systematic review and meta-analysis

Viswanatha, G. L., Shylaja, H., Nandakumar, K., Venkataranganna, M. V. & Prasad, N. B. L., 01-01-2020, (Accepted/In press) In : Pharmacological Reports.

Research output: Contribution to journalReview article

Hydroxychloroquine in COVID-19: Potential Mechanism of Action Against SARS-CoV-2

Satarker, S., Ahuja, T., Banerjee, M., Vignesh Balaji, E., Dogra, S., Agarwal, T. & Nampoothiri, M., 2020, (Accepted/In press) In : Current Pharmacology Reports.

Research output: Contribution to journalReview article

Open Access

Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In : European Journal of Medicinal Chemistry. 201, 112335.

Research output: Contribution to journalArticle

Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In : 3 Biotech. 10, 4, 149.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders

Ghosh, I., Sankhe, R., Mudgal, J., Arora, D. & Nampoothiri, M., 2020, (Accepted/In press) In : Neuropeptides. 102083.

Research output: Contribution to journalReview article

Structural Proteins in Severe Acute Respiratory Syndrome Coronavirus-2

Satarker, S. & Nampoothiri, M., 01-01-2020, (Accepted/In press) In : Archives of Medical Research.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

Thirupataiah, B., Reddy, G. S., Ghule, S. S., Kumar, J. S., Mounika, G., Hossain, K. A., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 04-2020, In : Bioorganic Chemistry. 97, 103691.

Research output: Contribution to journalArticle

Targeting SARS-CoV-2 Main Protease: A Computational Drug Repurposing Study

Baby, K., Maity, S., Mehta, C. H., Suresh, A., Nayak, U. Y. & Nayak, Y., 2020, (Accepted/In press) In : Archives of Medical Research.

Research output: Contribution to journalArticle

Open Access

Virgin coconut oil ameliorates colchicine induced cognitive dysfunction- A preclinical study

John, J., Sapa, N. K. & Shenoy, R. R., 03-2020, In : Pharmaceutical Sciences. 26, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access

Zinc as a plausible epigenetic modulator of glioblastoma multiforme

Balaji E, V., Kumar, N., Satarker, S. & Nampoothiri, M., 15-11-2020, In : European Journal of Pharmacology. 887, 173549.

Research output: Contribution to journalReview article

2019

Annona muricata fruit extract protects against diethylnitrosamine-induced hepatocellular cancer in rats

Thomas, S., Paul, J., Shrungeswara, A., Biswas, S., Shah, A., Subraya, C. & Nayak, Y., 01-06-2019, In : Asian Pacific Journal of Tropical Medicine. 12, 6, p. 272-282 11 p.

Research output: Contribution to journalArticle

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In : Biomedical Reports. 11, 2, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2 Citations (Scopus)

Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In : Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Citation (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Histogenesis and Histomorphometric study of Human Fetal Small Intestine

Salva, M. N., Gupta, C., Pandey, A. K., Kumar, N., Kotian, S. R. & Kalthur, S. G., 01-11-2019, In : Ethiopian journal of health sciences. 29, 6, p. 689-696 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In : European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Influence of traditional medicines on the activity of keratinocytes in wound healing: An in-vitro study

Kotian, S. R., Bhat, K. M. R., Padma, D. & Pai, K. S. R., 01-01-2019, In : Anatomy and Cell Biology. 52, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Medhya rasayana restores memory function against doxorubicin-induced cognitive decline: Possibly by its neuroprotective effect

Gourishetti, K., Ghetia, S., Jacob, L., Mallik, S. B., Nayak, P. G., Kishore, A., Nandakumar, K., Alnaseer, S. M. & Hussain, S. M., 01-04-2019, In : Indian Journal of Pharmaceutical Education and Research. 53, 2, p. S104-S111

Research output: Contribution to journalArticle

Open Access

Neprilysin, the kidney brush border neutral proteinase: a possible potential target for ischemic renal injury

Sankhe, R., Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2019, (Accepted/In press) In : Toxicology Mechanisms and Methods.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2 Citations (Scopus)

Poly(N,N-diethyl acrylamide)/functionalized graphene quantum dots hydrogels loaded with doxorubicin as a nano-drug carrier for metastatic lung cancer in mice

Havanur, S., Batish, I., Cheruku, S. P., Gourishetti, K., JagadeeshBabu, P. E. & Kumar, N., 01-12-2019, In : Materials Science and Engineering C. 105, 110094.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In : Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

Research output: Contribution to journalArticle