Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

2016

Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In : Andrologia. 48, 10, p. 1236-1243 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis, spectroscopic and anti tumor studies on copper(II) complex of orthohydroxypropiophenoneisonicotinoylhydrazone

Ramesh, G. N., Prathima, B., Rao, Y. S., Reddy, Y. P., Pai, K. S. R. & Reddy, A. V., 01-09-2016, In : Arabian Journal of Chemistry. 9, p. S404-S410

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In : Cytotechnology. 68, 6, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synthesis of newer piperidinyl chalcones and their anticancer activity in human cancer cell lines

Jayashree, B. S., Patel, H. H., Mathew, N. S. & Nayak, Y., 01-04-2016, In : Research on Chemical Intermediates. 42, 4, p. 3673-3688 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2 Citations (Scopus)
2 Citations (Scopus)
2015

Anti-tubercular activity of synthesized novel 2,5-disubstituted-1,3,4-oxadiazole derivatives

Ega, D., Attari, Z., Mudgal, J., Bairy, I., Vishnuprasad, S. & Nampurath, G. K., 2015, In : Indian Drugs. 52, 2, p. 40-44 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Durgashivaprasad, E., Attari, Z., Mudgal, J., Bairy, L. K., Vishnu Prasad, S. & Kutty Nampurath, G., 2015, In : Indian Drugs. 52, 2, p. 40-44. 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In : Pharmacognosy Magazine. 11, 44, p. S296-S302

Research output: Contribution to journalArticle

7 Citations (Scopus)

Curcumin loaded self assembled lipid-biopolymer nanoparticles for functional food applications

Pathak, L., Kanwal, A. & Agrawal, Y., 24-10-2015, In : Journal of Food Science and Technology. 52, 10, p. 6143-6156 14 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Design, development, drug-likeness, and molecular docking studies of novel piperidin-4-imine derivatives as antitubercular agents

Revathi, R., Perumal, R. V., Pai, K. S. R., Arunkumar, G., Sriram, D. & Kini, S. G., 2015, In : Drug Design, Development and Therapy. 9, p. 3779-3787 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Design, synthesis, antioxidant and anticancer activity of novel pyrazole derivatives

Mubeen, M., Kini, S. G. & Pai, K. S. R., 2015, In : Der Pharma Chemica. 7, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In : International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Effects of withania somnifera and tinospora cordifolia extracts on the side population phenotype of human epithelial cancer cells: Toward targeting multidrug resistance in cancer

Maliyakkal, N., Appadath Beeran, A., Balaji, S. A., Udupa, N., Ranganath Pai, S. & Rangarajan, A., 17-03-2015, In : Integrative Cancer Therapies. 14, 2, p. 156-171 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In : Journal of Ethnopharmacology. 168, p. 50-60 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Mitochondrial modulators in experimental Huntington's disease: Reversal of mitochondrial dysfunctions and cognitive deficits

Mehrotra, A., Kanwal, A., Banerjee, S. K. & Sandhir, R., 01-01-2015, In : Neurobiology of Aging. 36, 6, p. 2186-2200 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
36 Citations (Scopus)

Molecular docking, pharmacophore modeling and 3D-QSAR approach on a series of piperidone derivatives as potential anticancer agents by targeting the enzyme VEGFR-2 tyrosine kinase

Rajappan, R., Ramachandran, V. P., Ranganath Pai, K. S., Arunkumar, G., Rao, J. V., Jagani, H. & Kini, S. G., 2015, In : Der Pharma Chemica. 7, 4, p. 155-163 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated intrinsic pathway

Sankhe, N. M., Durgashivaprasad, E., Gopalan Kutty, N., Venkata Rao, J., Narayanan, K., Kumar, N., Jain, P., Udupa, N. & Vasanth Raj, P., 31-07-2015, (Accepted/In press) In : Arabian Journal of Chemistry.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Preparation, characterization and pharmacokinetic study of nelfinavir nanocrystals for oral bioavailability enhancement

Naresh, D. N., Nayak, U. Y., Musmade, P., Mutalik, S. & Nayak, Y., 2015, In : Current Nanoscience. 11, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Some new indole-coumarin hybrids; Synthesis, anticancer and Bcl-2 docking studies

Kamath, P. R., Sunil, D., Ajees, A. A., Pai, K. S. R. & Das, S., 2015, In : Bioorganic Chemistry. 63, p. 101-109 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Subacute toxicity study of lacidipine nanoformulation

Shirodkar, R., Reddy, N., Kumar, N., Ramalingayya, G., Mutalik, S. & Lewis, S., 26-09-2015, In : Latin American Journal of Pharmacy. 34, 8, p. 1526-1533 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents

Sankappa Rai, U., Isloor, A. M., Shetty, P., Pai, K. S. R. & Fun, H. K., 2015, In : Arabian Journal of Chemistry. 8, 3, p. 317-321 5 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Synthesis and pharmacological evaluation of some new fluorine containing hydroxypyrazolines as potential anticancer and antioxidant agents

[Unknown], D., Viveka, S., Priya, B. K., Pai, K. S. R., Naveen, S., Lokanath, N. K. & Nagaraja, G. K., 2015, In : European Journal of Medicinal Chemistry. 104, p. 25-32 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Targets in anticancer research-a review

Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In : Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

Anticonvulsant activity of fraction isolated from ethanolic extract of heartwood of Cedrus deodara

Dhayabaran, D., Florance, E. J., Nandakumar, K., Shanmugarathinam, A. & Puratchikody, A., 2014, In : Journal of Natural Medicines. 68, 2, p. 310-315 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Antidiabetic activity of 3-hydroxyflavone analogues in high fructose fed insulin resistant rats

Nayak, Y., Venkatachalam, H., Daroji, V. K., Mathew, G., Jayashree, B. S. & Unnikrishnan, M. K., 09-09-2014, In : EXCLI Journal. 13, p. 1055-1074 20 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Antidiabetic activity of benzopyrone analogues in nicotinamide-streptozotocin induced type 2 diabetes in rats

Nayak, Y., Hillemane, V., Daroji, V. K., Jayashree, B. S. & Unnikrishnan, M. K., 2014, In : Scientific World Journal. 2014, 854267.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Atypical antidepressant activity of 3,4-bis(3,4-dimethoxyphenyl) furan-2,5-dione isolated from heart wood of Cedrus deodara, in rodents

Kumar, N., Dhayabaran, D., Nampoothiri, M., Nandakumar, K., Puratchikody, A., Lalani, N., Dawood, K. & Ghosh, A., 01-10-2014, In : Korean Journal of Physiology and Pharmacology. 18, 5, p. 365-369 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
11 Citations (Scopus)

Curriculum for pharmacology in pharmacy institutions in India: Opportunities and challenges

Goyal, R. K., Bhise, S. B., Srinivasan, B. P., Rao, C. M., Sen, T. & Koneri, R., 2014, In : Indian Journal of Pharmacology. 46, 3, p. 241-245 5 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In : The Scientific World Journal. 2014, 430734.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Hepatoprotective role of Caesalpenia bonduc: A histopathological and biochemical study

Sumalatha, S., Pai, K. S. R., Kumar, N. & Bhat, K. M. R., 20-11-2014, In : Journal of Clinical and Diagnostic Research. 8, 11, p. HF05-HF07

Research output: Contribution to journalArticle

4 Citations (Scopus)

Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In : BioMed Research International. 2014, 569130.

Research output: Contribution to journalArticle

6 Citations (Scopus)
10 Citations (Scopus)

Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

Nampoothiri, M., Reddy, N. D., John, J., Kumar, N., Kutty Nampurath, G. & Rao Chamallamudi, M., 2014, In : Behavioural Neurology. 2014, 674164.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In : The Scientific World Journal. 2014, 673248.

Research output: Contribution to journalArticle

8 Citations (Scopus)

In vitro cytotoxic and apoptotic effect of Mimusops elengi Linn. methanolic bark extract

Kumar, H., Pai, K. S. R., Maliyakkal, N., Mihir, S. & Singh, C., 2014, In : Biomedicine and Preventive Nutrition. 4, 4, p. 579-588 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

Durgashivaprasad, E., Mathew, G., Sebastian, S., Manohar Reddy, S. A., Mudgal, J. & Nampurath, G. K., 2014, In : Indian Journal of Pharmacology. 46, 5, p. 521-526 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In : Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis

Patel, A., Biswas, S., Shoja, M. H., Ramalingayya, G. V. & Nandakumar, K., 2014, In : The Scientific World Journal. 2014, p. 345939

Research output: Contribution to journalArticle

8 Citations (Scopus)

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In : Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In : Pharmacological Reports. 66, 5, p. 788-798 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
3 Citations (Scopus)