Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

2014

Synthesis and characterization of 2-(4-((1-alkyl or aryl-1H-1,2,3-triazol- 4-yl)methoxy)phenyl)naphtho[1,2-d]oxazoles for protein tyrosine phosphatase 1B inhibitory activity

Madabhushi, S., Chinthala, N., Kanwal, A., Kaur, G. & Banerjee, S. K., 01-01-2014, In : Medicinal Chemistry Research. 23, 4, p. 2062-2069 8 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of novel triazoles and mannich bases functionalized 1,4-dihydropyridine as angiotensin converting enzyme (ACE) inhibitors

Kumbhare, R. M., Kosurkar, U. B., Bagul, P. K., Kanwal, A., Appalanaidu, K., Dadmal, T. L. & Banerjee, S. K., 01-11-2014, In : Bioorganic and Medicinal Chemistry. 22, 21, p. 5824-5830 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Synthesis of l-rhamnose derived chiral bicyclic triazoles as novel sodium-glucose transporter (SGLT) inhibitors

Putapatri, S. R., Kanwal, A., Sridhar, B., Banerjee, S. K. & Kantevari, S., 14-11-2014, In : Organic and Biomolecular Chemistry. 12, 42, p. 8415-8421 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Synthesis of novel l-rhamnose derived acyclic C-nucleosides with substituted 1,2,3-triazole core as potent sodium-glucose co-transporter (SGLT) inhibitors

Putapatri, S. R., Kanwal, A., Banerjee, S. K. & Kantevari, S., 15-03-2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 6, p. 1528-1531 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In : Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2013

Antidiabetic, Antihyperlipidemic and Antioxidant Effects of the Flavonoids

Unnikrishnan, M. K., Veerapur, V., Nayak, Y., Mudgal, P. P. & Mathew, G., 11-2013, Polyphenols in Human Health and Disease. Elsevier Inc., Vol. 1. p. 143-161 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Citations (Scopus)

Antioxidant and antihyperlipidemic activity of Melia azedarach Linn. extracts in rats

Vijaya Kumar, S., Sanghai, D. B., Mallikarjuna Rao, C. & Shreedhara, C. S., 2013, In : Research Journal of Pharmacy and Technology. 6, 11, p. 1195-1199 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A rat model against chemotherapy plus radiation-induced oral mucositis

Patel, A., Rajesh, S., Chandrashekhar, V. M., Rathnam, S., Shah, K., Mallikarjuna Rao, C. & Nandakumar, K., 10-2013, In : Saudi Pharmaceutical Journal. 21, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
21 Citations (Scopus)

Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: A new therapeutic implication

Gupta, P., Kanwal, A., Putcha, U. K., Bulani, Y., Sojitra, B., Khatua, T. N., Kuncha, M. & Banerjee, S. K., 26-03-2013, In : Journal of Translational Medicine. 11, 1, 80.

Research output: Contribution to journalArticle

18 Citations (Scopus)
22 Citations (Scopus)

Design, synthesis and evaluation of novel 2-hydroxypyrrolobenzodiazepine-5, 11-dione analogues as potent angiotensin converting enzyme (ACE) inhibitors

Addla, D., Jallapally, A., Kanwal, A., Sridhar, B., Banerjee, S. K. & Kantevari, S., 01-08-2013, In : Bioorganic and Medicinal Chemistry. 21, 15, p. 4485-4493 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Evaluation of in vitro antioxidant and in Vivo analgesic potential of Terminalia paniculata aqueous bark extract

Talwar, S., Nayak, P. G., Mudgal, J., Paul, P., Bansal, P. & Nandakumar, K., 2013, In : Journal of Medicinal Food. 16, 12, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Formulation optimization and evaluation of aceclofenac sustained release dosage form based on kollidon sustained release

Panikkarakayil, H., Nampoothiri, M., Kachappilly, G., Shameem, M., Pariyani, R. & Anitha, Y., 2013, In : Asian Journal of Pharmaceutics. 7, 1, p. 8-14 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hypoglycaemic effects of alcoholic root extract of Borassus flabellifer (Linn.) in normal and diabetic rats

Debnath, T., Radhakrishnan, R., Gopal, M., Talwar, S. & Nandakumar, K., 2013, In : Pakistan Journal of Pharmaceutical Sciences. 26, 4, p. 673-679 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Impact of caffeic acid on aluminium chloride-induced dementia in rats

Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In : Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In : Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
3 Citations (Scopus)

In vivo anticancer and histopathology studies of Schiff bases on Ehrlich ascitic carcinoma cells. 1st Cancer Update.

Sunil, D., Isloor, A. M., Shetty, P., Nayak, P. G. & Pai, K. S. R., 2013, In : Arabian Journal of Chemistry. 6, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In : Pharmacological Reports. 65, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
39 Citations (Scopus)

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In : American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Preventive role of Emblica offcinalis and Cissus quadrangularis on bone loss in osteoporosis

Sirasanagandla, S. R., Sreedhara Ranganath Pai, K. & Bhat, K. M. R., 02-12-2013, In : International Journal of Pharmacy and Pharmaceutical Sciences. 5, SUPPL.4, p. 122-127 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts

Nayak, P. G., Paul, P., Bansal, P., Kutty, N. G. & Pai, K. S. R., 2013, In : Journal of Pharmacy and Pharmacology. 65, 7, p. 1083-1093 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In : Lipids. 48, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

SGLT inhibitors: A novel target for diabetes

Kanwal, A. & Banerjee, S. K., 01-01-2013, In : Pharmaceutical patent analyst. 2, 1, p. 77-91 15 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells

Isloor, A. M., Sunil, D., Shetty, P., Malladi, S., Pai, K. S. R. & Maliyakkl, N., 2013, In : Medicinal Chemistry Research. 22, 2, p. 758-767 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

Raghu, J., Raghuveer, V. C., Rao, M. C., Somayaji, N. S. & Babu, P. B., 2013, In : Interdisciplinary Toxicology. 6, 4, p. 217-221 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
14 Citations (Scopus)
2012

Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In : Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In : Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Anticonvulsant activity of alcoholic root extract of Cardiospermum halicacabum

Dhayabaran, D., Florance, J., Krsihnadas, N., [Unknown], I. & Varma, M., 2012, In : Brazilian Journal of Pharmacognosy. 22, 3, p. 623-629 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice

Bansal, P., Paul, P., Mudgal, J., G. Nayak, P., Thomas Pannakal, S., Priyadarsini, K. I. & Unnikrishnan, M. K., 2012, In : Experimental and Toxicologic Pathology. 64, 6, p. 651-658 8 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Antiglycation and anticancer activity of some newer synthetic flavones

Jayashree, B. S., Chaturvedi, P., Venkatachalam, H., Chaudary, P. V. R. & Nayak, Y., 2012, In : Der Pharma Chemica. 4, 4, p. 1626-1630 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Benzopyran-4-one is an ideal pharmacophore for lead optimization in antidiabetic drug discovery

Nayak, Y., Jayashree, B. S. & Unnikrishnan, M. K., 2012, In : Research Journal of Pharmacy and Technology. 5, 8, p. 1025-1033 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Click Chemistry Approach for Bis-Chromenyl Triazole Hybrids and Their Antitubercular Activity

Naik, R. J., Kulkarni, M. V., Sreedhara Ranganath Pai, K. & Nayak, P. G., 2012, In : Chemical Biology and Drug Design. 80, 4, p. 516-523 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Development of a cell-based nonradioactive glucose uptake assay system for SGLT1 and SGLT2

Kanwal, A., Singh, S. P., Grover, P. & Banerjee, S. K., 01-10-2012, In : Analytical Biochemistry. 429, 1, p. 70-75 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In : Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Histological and physiochemical standardization of Melia azedarach. Linn bark

Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In : Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

Research output: Contribution to journalArticle

4 Citations (Scopus)

In-vitroAntidiabetic activity of stem bark of Bauhinia purpurea Linn

Daksha, G., Chandrashekar, Lobo, R., Nayak, Y. & Nilesh, G., 2012, In : Der Pharmacia Lettre. 4, 2, p. 614-619 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Isolation and anxiolytic activity of 3,4-bis(3,4-dimethoxyphenyl) furan-2,5-dione from the ethanolic extract of heart wood of Cedrus deodara

Dhayabaran, D., Florance, J., Nandakumar, K. & Puratchikody, A., 2012, In : Medicinal Chemistry Research. 21, 11, p. 3460-3464 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Nitric oxide synthase inhibition abrogates hydrogen sulfide-induced cardioprotection in mice

Sojitra, B., Bulani, Y., Putcha, U. K., Kanwal, A., Gupta, P., Kuncha, M. & Banerjee, S. K., 01-01-2012, In : Molecular and Cellular Biochemistry. 360, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

NO-NSAIDs. Part 3: Nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs

Borhade, N., Pathan, A. R., Halder, S., Karwa, M., Dhiman, M., Pamidiboina, V., Gund, M., Deshattiwar, J. J., Mali, S. V., Deshmukh, N. J., Senthilkumar, S. P., Gaikwad, P., Tipparam, S. G., Mudgal, J., Dutta, M. C., Burhan, A. U., Thakre, G., Sharma, A., Deshpande, S., Desai, D. C. & 5 others, Dubash, N. P., Jain, A. K., Sharma, S., Nemmani, K. V. S. & Satyam, A., 01-04-2012, In : Chemical and Pharmaceutical Bulletin. 60, 4, p. 465-481 17 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Pharmacophore modeling of delta and MU receptors and synthesis of enkephalines with D-[Leu] 5 C-terminal modification as delta selective agonists

Bhat, P., Mor, V., Muttineni, R., Pai, K. S. R., Chowdary, P. V. R. & Kota, S., 2012, In : International Journal of Pharmacy and Technology. 4, 2, p. 4350-4391 42 p.

Research output: Contribution to journalArticle

Prevalence of post stroke complications in South India: A descriptive study

Sreeraj, K., Iype, T., Madhavan, N. & Balan, C. S., 2012, In : International Journal of Pharmacy and Technology. 4, 1, p. 3859-3868 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis and antihistaminic activity of 3H-benzo [4,5] thieno [2,3-d][1,2,3] triazin-4-ones

Viswanatha, G. L., Priyadarshini, B. J., Krishnadas, N., Janardhanan, S., Rangappa, S. & Hanumanthappa, S., 2012, In : Saudi Pharmaceutical Journal. 20, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Synthesis of 3-methylflavones and their antioxidant and antibacterial activities

Jayashree, B. S., Alam, A., Nayak, Y. & Vijay Kumar, D., 08-2012, In : Medicinal Chemistry Research. 21, 8, p. 1991-1996 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2011

Ameliorative effect of caffeic acid against inflammatory pain in rodents

Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In : European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)