Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

Article

Long-term exposure to a butter-rich diet induces mild-to-moderate steatosis in Chang liver cells and Swiss albino mice models

Nalloor, T. J. P., Kumar, N., Narayanan, K. & Palanimuthu, V. R., 01-05-2017, In : Journal of Basic and Clinical Physiology and Pharmacology. 28, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

Lymphatic delivery of anti-HIV drug nanoparticles

Nayak, Y., Avadhani, K., Mutalik, S. & Nayak, U. Y., 01-08-2016, In : Recent Patents on Nanotechnology. 10, 2, p. 116-127 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Medhya rasayana restores memory function against doxorubicin-induced cognitive decline: Possibly by its neuroprotective effect

Gourishetti, K., Ghetia, S., Jacob, L., Mallik, S. B., Nayak, P. G., Kishore, A., Nandakumar, K., Alnaseer, S. M. & Hussain, S. M., 01-04-2019, In : Indian Journal of Pharmaceutical Education and Research. 53, 2, p. S104-S111

Research output: Contribution to journalArticle

Open Access

Mitochondrial modulators in experimental Huntington's disease: Reversal of mitochondrial dysfunctions and cognitive deficits

Mehrotra, A., Kanwal, A., Banerjee, S. K. & Sandhir, R., 01-01-2015, In : Neurobiology of Aging. 36, 6, p. 2186-2200 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Modulation of doxorubicin-induced cardiotoxicity by averrhoa bilimbi extract

Francis, A. & Nayak, Y., 2017, In : Journal of Young Pharmacists. 9, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In : Pharmacological Reports. 65, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Modulatory role of mucuna pruriens against aluminium fluoride induced neuronal and behavioural alterations in rats

Nayak, V. S., Kumar, N., Dsouza, A. S., Nayak, S. S. & Pai, K. S. R., 01-04-2018, In : Journal of Clinical and Diagnostic Research. 12, 4, p. FC01-FC04

Research output: Contribution to journalArticle

40 Citations (Scopus)

Molecular docking, pharmacophore modeling and 3D-QSAR approach on a series of piperidone derivatives as potential anticancer agents by targeting the enzyme VEGFR-2 tyrosine kinase

Rajappan, R., Ramachandran, V. P., Ranganath Pai, K. S., Arunkumar, G., Rao, J. V., Jagani, H. & Kini, S. G., 2015, In : Der Pharma Chemica. 7, 4, p. 155-163 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Mosquito larvicidal activity of Vitex negundo

Vasanth Raj, P., Raghu Chandrasekhar, H., Dhanaraj, S. A., Vijayan, P., Nitesh, K., Subrahmanyam, V. M. & Venkata Rao, J., 2009, In : Pharmacologyonline. 2, p. 975-990 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Naringin ameliorates doxorubicin-induced neurotoxicity in vitro and cognitive dysfunction in vivo

Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Mallik, S. B., Gourishetti, K., Hussain, S. M., Rao, C. M. & Nandakumar, K., 01-04-2018, In : Pharmacognosy Magazine. 14, 55, p. S197-S207

Research output: Contribution to journalArticle

2 Citations (Scopus)
27 Citations (Scopus)
2 Citations (Scopus)

Nitric oxide synthase inhibition abrogates hydrogen sulfide-induced cardioprotection in mice

Sojitra, B., Bulani, Y., Putcha, U. K., Kanwal, A., Gupta, P., Kuncha, M. & Banerjee, S. K., 01-01-2012, In : Molecular and Cellular Biochemistry. 360, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Nitrooxyethylation reverses the healing-suppressant effect of ibuprofen

Kaushal, M., Kutty, N. & Rao, C., 2006, In : Mediators of Inflammation. 2006, 24396.

Research output: Contribution to journalArticle

3 Citations (Scopus)

NO-NSAIDs. Part 3: Nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs

Borhade, N., Pathan, A. R., Halder, S., Karwa, M., Dhiman, M., Pamidiboina, V., Gund, M., Deshattiwar, J. J., Mali, S. V., Deshmukh, N. J., Senthilkumar, S. P., Gaikwad, P., Tipparam, S. G., Mudgal, J., Dutta, M. C., Burhan, A. U., Thakre, G., Sharma, A., Deshpande, S., Desai, D. C. & 5 others, Dubash, N. P., Jain, A. K., Sharma, S., Nemmani, K. V. S. & Satyam, A., 01-04-2012, In : Chemical and Pharmaceutical Bulletin. 60, 4, p. 465-481 17 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats

Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 27-01-2011, In : Journal of Ethnopharmacology. 133, 2, p. 608-612 5 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated intrinsic pathway

Sankhe, N. M., Durgashivaprasad, E., Gopalan Kutty, N., Venkata Rao, J., Narayanan, K., Kumar, N., Jain, P., Udupa, N. & Vasanth Raj, P., 31-07-2015, (Accepted/In press) In : Arabian Journal of Chemistry.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

Durgashivaprasad, E., Mathew, G., Sebastian, S., Manohar Reddy, S. A., Mudgal, J. & Nampurath, G. K., 2014, In : Indian Journal of Pharmacology. 46, 5, p. 521-526 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
4 Citations (Scopus)

Novel Indole-Quinazolinone Based Amides as Cytotoxic Agents

Gokhale, N., Panathur, N., Dalimba, U., Nayak, P. G. & Pai, K. S. R., 01-03-2016, In : Journal of Heterocyclic Chemistry. 53, 2, p. 513-524 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
20 Citations (Scopus)
2 Citations (Scopus)

Oral antidiabetic activities of different extracts of Caesalpinia bonducella seed kernels

Parameshwar, S., Srinivasan, K. K. & Rao, C. M., 2002, In : Pharmaceutical Biology. 40, 8, p. 590-595 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
3 Citations (Scopus)
3 Citations (Scopus)

Petroleum ether extract of cissus quadrangularis (linn.) enhances bone marrow mesenchymal stem cell proliferation and facilitates osteoblastogenesis

Potu, B. K., Bhat, K. M. R., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Nayak, S. R. & Muttigi, M. S., 2009, In : Clinics. 64, 10, p. 993-998 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Petroleum ether extract of Cissus quadrangularis (Linn) stimulates the growth of fetal bone during intra uterine developmental period: A morphometric analysis

Potu, B. K., Rao, M. S., Kutty N, G., Bhat, K. M. R., Chamallamudi, M. R. & Nayak, S. R., 2008, In : Clinics. 63, 6, p. 815-820 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
1 Citation (Scopus)

Pharmacophore modeling of delta and MU receptors and synthesis of enkephalines with D-[Leu] 5 C-terminal modification as delta selective agonists

Bhat, P., Mor, V., Muttineni, R., Pai, K. S. R., Chowdary, P. V. R. & Kota, S., 2012, In : International Journal of Pharmacy and Technology. 4, 2, p. 4350-4391 42 p.

Research output: Contribution to journalArticle

Phytochemical screening and antioxidant activity of Heracleum afghanicum Kitamura leaves

Amini, M. H., Kalsi, V., Kaur, B., Khatik, G. L., Lobo, R., Singh, G., Agarhari, U. C., Yele, S. & Suttee, A., 01-10-2017, In : Research Journal of Pharmacy and Technology. 10, 10, p. 3498-3502 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Pinocembrin enriched fraction of Elytranthe parasitica (L.) Danser induces apoptosis in HCT 116 colorectal cancer cells

Kumar, N., Biswas, S., Hosur Shrungeswara, A., Basu Mallik, S., Hipolith Viji, M., Elizabeth Mathew, J., Mathew, J., Nandakumar, K. & Lobo, R., 01-06-2017, In : Journal of Infection and Chemotherapy. 23, 6, p. 354-359 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Pinocembrin-Enriched Fractions of Elytranthe parasitica (L.) Danser Modulates Apoptotic and MAPK Cellular Signaling in HepG2 Cells

Kumar, N., Shrungeswara, A. H., Mallik, S. B., Biswas, S., Mathew, J., Nandakumar, K., Mathew, J. & Lobo, R., 01-01-2018, In : Anti-cancer agents in medicinal chemistry. 18, 11, p. 1563-1572 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Poly(N,N-diethyl acrylamide)/functionalized graphene quantum dots hydrogels loaded with doxorubicin as a nano-drug carrier for metastatic lung cancer in mice

Havanur, S., Batish, I., Cheruku, S. P., Gourishetti, K., JagadeeshBabu, P. E. & Kumar, N., 01-12-2019, In : Materials Science and Engineering C. 105, 110094.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
3 Citations (Scopus)

Preclinical pharmacokinetics and biodistribution studies of asenapine maleate using novel and sensitive RP-HPLC method

Managuli, R. S., Gourishetti, K., Shenoy, R. R., Koteshwara, K. B., Reddy, M. S. & Mutalik, S., 01-07-2017, In : Bioanalysis. 9, 14, p. 1037-1047 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice

Nigade, P. B., Gundu, J., Sreedhara Pai, K. & Nemmani, K. V. S., 01-10-2017, In : European Journal of Drug Metabolism and Pharmacokinetics. 42, 5, p. 835-847 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prediction of Tumor-to-Plasma Ratios of Basic Compounds in Subcutaneous Xenograft Mouse Models

Nigade, P. B., Gundu, J., Pai, K. S. & Nemmani, K. V. S., 01-06-2018, In : European Journal of Drug Metabolism and Pharmacokinetics. p. 1-16 16 p.

Research output: Contribution to journalArticle

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
42 Citations (Scopus)

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In : American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In : Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Preliminary phytochemical studies and antimicrobial activity of stem bark of Thespesia populnea

Viswanatha, G. L., Shylaja, H., Srinath, R., Nandakumar, K. & Ramesh, C., 10-10-2008, In : Pharmacologyonline. 2, p. 467-470 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Preparation, characterization and pharmacokinetic study of nelfinavir nanocrystals for oral bioavailability enhancement

Naresh, D. N., Nayak, U. Y., Musmade, P., Mutalik, S. & Nayak, Y., 2015, In : Current Nanoscience. 11, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Preparation of indegenous herbal formulation and its evalaution for antidiabetic activity

Murugananthan, G., Deep, P., Kumar, R. & Nandakumar, K., 2010, In : Pharmacologyonline. 2, p. 275-282 8 p.

Research output: Contribution to journalArticle

Prevalence of post stroke complications in South India: A descriptive study

Sreeraj, K., Iype, T., Madhavan, N. & Balan, C. S., 2012, In : International Journal of Pharmacy and Technology. 4, 1, p. 3859-3868 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)