Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal

  • India

  • Madhava Nagar, MCOPS Building

    576104 Manipal

    India

Research Output

Filter
Article
2021

Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico study

Sankhe, R., Rathi, E., Manandhar, S., Kumar, A., Pai, S. R. K., Kini, S. G. & Kishore, A., 15-01-2021, In : Journal of Molecular Structure. 1224, 129073.

Research output: Contribution to journalArticle

Open Access
2020

A Review on Anticancer Potentials of Benzothiazole Derivatives

Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In : Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 2020, (Accepted/In press) In : Andrologia.

Research output: Contribution to journalArticle

Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In : 3 Biotech. 10, 10, 438.

Research output: Contribution to journalArticle

Open Access

Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In : European Journal of Medicinal Chemistry. 201, 112335.

Research output: Contribution to journalArticle

Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In : 3 Biotech. 10, 4, 149.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

Thirupataiah, B., Reddy, G. S., Ghule, S. S., Kumar, J. S., Mounika, G., Hossain, K. A., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 04-2020, In : Bioorganic Chemistry. 97, 103691.

Research output: Contribution to journalArticle

Open Access

Virgin coconut oil ameliorates colchicine induced cognitive dysfunction- A preclinical study

John, J., Sapa, N. K. & Shenoy, R. R., 03-2020, In : Pharmaceutical Sciences. 26, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
2019

Annona muricata fruit extract protects against diethylnitrosamine-induced hepatocellular cancer in rats

Thomas, S., Paul, J., Shrungeswara, A., Biswas, S., Shah, A., Subraya, C. & Nayak, Y., 01-06-2019, In : Asian Pacific Journal of Tropical Medicine. 12, 6, p. 272-282 11 p.

Research output: Contribution to journalArticle

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In : Biomedical Reports. 11, 2, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2 Citations (Scopus)

Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In : Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Citation (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Histogenesis and Histomorphometric study of Human Fetal Small Intestine

Salva, M. N., Gupta, C., Pandey, A. K., Kumar, N., Kotian, S. R. & Kalthur, S. G., 01-11-2019, In : Ethiopian journal of health sciences. 29, 6, p. 689-696 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In : European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Influence of traditional medicines on the activity of keratinocytes in wound healing: An in-vitro study

Kotian, S. R., Bhat, K. M. R., Padma, D. & Pai, K. S. R., 01-01-2019, In : Anatomy and Cell Biology. 52, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Medhya rasayana restores memory function against doxorubicin-induced cognitive decline: Possibly by its neuroprotective effect

Gourishetti, K., Ghetia, S., Jacob, L., Mallik, S. B., Nayak, P. G., Kishore, A., Nandakumar, K., Alnaseer, S. M. & Hussain, S. M., 01-04-2019, In : Indian Journal of Pharmaceutical Education and Research. 53, 2, p. S104-S111

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Poly(N,N-diethyl acrylamide)/functionalized graphene quantum dots hydrogels loaded with doxorubicin as a nano-drug carrier for metastatic lung cancer in mice

Havanur, S., Batish, I., Cheruku, S. P., Gourishetti, K., JagadeeshBabu, P. E. & Kumar, N., 01-12-2019, In : Materials Science and Engineering C. 105, 110094.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In : Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

Research output: Contribution to journalArticle

Targeting HIV-TB coinfection by developing novel piperidin-4-substituted imines: Design, synthesis, in vitro and in silico studies

Kumar, A., Revathi, R., Sriram, D., Curreli, F., Debnath, A. K., Pai, K. S. & Kini, S. G., 01-06-2019, In : Archiv der Pharmazie. 352, 6, 1800358.

Research output: Contribution to journalArticle

Terminalia tomentosa bark ameliorates inflammation and arthritis in carrageenan induced inflammatory model and freund's adjuvant-induced arthritis model in rats

Jitta, S. R., Daram, P., Gourishetti, K., Misra, C. S., Polu, P. R., Shah, A., Shreedhara, C. S., Nampoothiri, M. & Lobo, R., 01-01-2019, In : Journal of Toxicology. 2019, 7898914.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy

Kanwal, A., Pillai, V. B., Samant, S., Gupta, M. & Gupta, M. P., 12-07-2019, In : FASEB Journal. p. fj201900767R

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

Amelioration of arsenic-induced oxidative stress in CHO cells by Ixora coccinea flower extract

Salmataj, S. A., Kamath, S. U., Murty, V. R. & Pai, S. R., 01-10-2018, In : 3 Biotech. 8, 10, 446.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An Appraisal of Pumpkin Seed Extract in 1, 2-Dimethylhydrazine Induced Colon Cancer in Wistar Rats

Chari, K. Y., Polu, P. R. & Shenoy, R. R., 01-01-2018, In : Journal of Toxicology. 2018, 6086490.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 03-10-2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antimicrobial activity of aqueous and ethanolic leaf extracts of anacardium occidentale

Shobha, K. L., Rao, A. S., Pai, K. S. R. & Bhat, S., 01-12-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 12, p. 474-476 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2 Citations (Scopus)

Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In : Cytotechnology. p. 1-15 15 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In : Andrologia. 50, 7, e13037.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)
1 Citation (Scopus)

Development of ritonavir solid lipid nanoparticles by Box Behnken design for intestinal lymphatic targeting

Kumar, S., Narayan, R., Ahammed, V., Nayak, Y., Naha, A. & Nayak, U. Y., 01-04-2018, In : Journal of Drug Delivery Science and Technology. 44, p. 181-189 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model

Gill, M., Kinra, M., Rai, A., Chamallamudi, M. R. & Kumar, N., 01-01-2018, In : NeuroReport. 29, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Evaluation of the aphrodisiac potential of a chemically characterized aqueous extract of Tamarindus indica pulp

Rai, A., Das, S., Chamallamudi, M. R., Nandakumar, K., Shetty, R., Gill, M., Sumalatha, S., Devkar, R., Gourishetti, K. & Kumar, N., 10-01-2018, In : Journal of Ethnopharmacology. 210, p. 118-124 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)