Department of Public Health Genomics, Manipal School of Life Sciences, Manipal

  • India

Research Output 1998 2019

2019
Open Access
Refugees
Health
Health Insurance
Delivery of Health Care
Referral and Consultation
Open Access
Iraq
Mental Health
Genocide
Syria
Long-Term Care

Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

Hines, P. A., Guy, R. H., Brand, A., Humphreys, A. J. & Papaluca-Amati, M., 01-01-2019, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Research
Interviews
Technology
Therapeutics

Scanning the horizon: A systematic literature review of methodologies

Hines, P., Hiu Yu, L., Guy, R. H., Brand, A. & Papaluca-Amati, M., 01-05-2019, In : BMJ Open. 9, 5, e026764.

Research output: Contribution to journalReview article

Open Access
Literature
Practice Guidelines
PubMed
Uncertainty
Decision Making

The Creation and Management of Innovations in Healthcare and ICT: The European and African Experience

Halfmann, S. S. G., Evangelatos, N., Kweyu, E., Devilliers, C., Steinhausen, K., Van Der Merwe, A. & Brand, A., 01-08-2019, In : Public Health Genomics. 21, 5-6, p. 197-206 10 p.

Research output: Contribution to journalArticle

Delivery of Health Care
2018
2 Citations (Scopus)

Antibiotics-Induced Obesity: A Mitochondrial Perspective

Andrade, M. J., Jayaprakash, C., Bhat, S., Evangelatos, N., Brand, A. & Satyamoorthy, K., 01-04-2018, In : Public Health Genomics.

Research output: Contribution to journalArticle

Obesity
Anti-Bacterial Agents
Molecular Biology
Genetic Predisposition to Disease
Epigenomics
1 Citation (Scopus)

Attitudes towards personal genomics and sharing of genetic data among older swiss adults: A qualitative study

Mählmann, L., Schee Gen Halfmann, S., Von Wyl, A. & Brand, A., 01-04-2018, In : Public Health Genomics. 20, 5, p. 293-306 14 p.

Research output: Contribution to journalArticle

Information Dissemination
Genomics
Interviews
Research
Motivation
2 Citations (Scopus)

Big Data for Public Health Policy-Making: Policy Empowerment

Mählmann, L., Reumann, M., Evangelatos, N. & Brand, A., 01-08-2018, In : Public Health Genomics. 20, 6, p. 312-320 9 p.

Research output: Contribution to journalArticle

Policy Making
Public Policy
Health Policy
Public Health
Health
1 Citation (Scopus)

Maternal sepsis in the era of genomic medicine

Kouskouti, C., Evangelatos, N., Brand, A. & Kainer, F., 01-01-2018, (Accepted/In press) In : Archives of Gynecology and Obstetrics. p. 1-12 12 p.

Research output: Contribution to journalArticle

Sepsis
Mothers
Medicine
Technology
Systems Biology
4 Citations (Scopus)

Metabolomics in sepsis and its impact on public health

Evangelatos, N., Bauer, P., Reumann, M., Satyamoorthy, K., Lehrach, H. & Brand, A., 01-04-2018, In : Public Health Genomics. 20, 5, p. 274-285 12 p.

Research output: Contribution to journalReview article

Metabolomics
Sepsis
Public Health
Research
Technology
4 Citations (Scopus)

Multi-Omics Research Trends in Sepsis: A Bibliometric, Comparative Analysis between the United States, the European Union 28 Member States, and China

Evangelatos, N., Satyamoorthy, K., Levidou, G., Bauer, P., Brand, H., Kouskouti, C., Lehrach, H. & Brand, A., 01-03-2018, In : OMICS A Journal of Integrative Biology. 22, 3, p. 190-197 8 p.

Research output: Contribution to journalArticle

Bibliometrics
European Union
China
Sepsis
Research
5 Citations (Scopus)

Personalized health in a public health perspective

Evangelatos, N., Satyamoorthy, K. & Brand, A., 01-05-2018, In : International Journal of Public Health. p. 1-2 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Potentials and Challenges of the Health Data Cooperative Model

Van Roessel, I., Reumann, M. & Brand, A., 01-08-2018, In : Public Health Genomics. 20, 6, p. 321-331 11 p.

Research output: Contribution to journalArticle

Health
Computer Security
Information Storage and Retrieval
Delivery of Health Care
Patient Participation

The genomic medicine alliance: A global effort to facilitate the introduction of genomics into healthcare in developing nations

Cooper, D. N., Mitropoulou, C., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Lee, M. T. M., Macek, M., Mitropoulos, K., Al-Mulla, F., Prainsack, B., van Schaik, R. H., Squassina, A., Taruscio, D., Vayena, E., Vozikis, A., Williams, M. S., Ylstra, B. & Patrinos, G. P., 01-01-2018, Genomic Medicine in Emerging Economies: Genomics for Every Nation. Elsevier, p. 173-188 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genomics
Developing Countries
Medicine
Delivery of Health Care
Research
Bibliometrics
China
Sepsis
Software
Research
2017

Challenges for small biopharmaceutical companies

Evangelatos, N. & Brand, A., 27-04-2017, In : New England Journal of Medicine. 376, 17, 1 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

Epigenomics, Pharmacoepigenomics, and Personalized Medicine in Cervical Cancer

Kabekkodu, S. P., Chakrabarty, S., Ghosh, S., Brand, A. & Satyamoorthy, K., 01-09-2017, In : Public Health Genomics. 20, 2, p. 100-115 16 p.

Research output: Contribution to journalReview article

Precision Medicine
Epigenomics
Uterine Cervical Neoplasms
Histone Code
Untranslated RNA
5 Citations (Scopus)

European healthcare systems readiness to shift from 'one-size fits all' to personalized medicine

Schee Genannt Halfmann, S., Evangelatos, N., Schröder-Bäck, P. & Brand, A., 01-01-2017, In : Personalized Medicine. 14, 1, p. 63-74 12 p.

Research output: Contribution to journalReview article

Precision Medicine
Delivery of Health Care
Health Literacy
2 Citations (Scopus)

Personalized medicine: What’s in it for rare diseases?

Schee Genannt Halfmann, S., Mählmann, L., Leyens, L., Reumann, M. & Brand, A., 01-01-2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 387-404 18 p. (Advances in Experimental Medicine and Biology; vol. 1031).

Research output: Chapter in Book/Report/Conference proceedingChapter

Precision Medicine
Rare Diseases
Medicine
Delivery of Health Care
Cardiology
14 Citations (Scopus)

Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy

Vozikis, A., Cooper, D. N., Mitropoulou, C., Kambouris, M. E., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Lee, M. T. M., Leyens, L., Macek, M., Al-Mulla, F., Prainsack, B., Squassina, A., Taruscio, D., Van Schaik, R. H., Vayena, E., Williams, M. S. & Patrinos, G. P., 01-01-2017, In : Public Health Genomics. 19, 6, p. 352-363 12 p.

Research output: Contribution to journalArticle

Medicine
Delivery of Health Care
Costs and Cost Analysis
Budgets
Cost-Benefit Analysis
14 Citations (Scopus)

Use of big data for drug development and for public and personal health and care

Leyens, L., Reumann, M., Malats, N. & Brand, A., 01-01-2017, In : Genetic Epidemiology. 41, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Public Health
Drug Discovery
Delivery of Health Care
Pharmaceutical Preparations
Explosions
2016
8 Citations (Scopus)

Attitudes towards personal genomics among older Swiss adults: An exploratory study

Mählmann, L., Röcke, C., Brand, A., Hafen, E. & Vayena, E., 01-03-2016, In : Applied and Translational Genomics. 8, p. 9-15 7 p.

Research output: Contribution to journalArticle

Genomics
Research
Metagenomics
Privacy
Health
10 Citations (Scopus)
Information Dissemination
Clinical Trials
Industry
Research
14 Citations (Scopus)

Early Patient Access to Medicines: Health Technology Assessment Bodies Need to Catch Up with New Marketing Authorization Methods

Leyens, L. & Brand, A., 01-06-2016, In : Public Health Genomics. 19, 3, p. 187-191 5 p.

Research output: Contribution to journalArticle

Biomedical Technology Assessment
Marketing
Medicine
International Agencies
United States Food and Drug Administration
2 Citations (Scopus)

Perspectives on translational genomics and public health in India

Chakrabarty, S., Kabekkodu, S. P., Brand, A. & Satyamoorthy, K., 01-04-2016, In : Public Health Genomics. 19, 2, p. 61-68 8 p.

Research output: Contribution to journalReview article

Genomics
India
Public Health
Precision Medicine
Information Science
7 Citations (Scopus)

Public Health Genomics: the essential part for good governance in public health

Brand, A., Evangelatos, N. & Satyamoorthy, K., 01-05-2016, In : International Journal of Public Health. 61, 4, p. 401-403 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Toward the integration of Omics data in epidemiological studies: still a “long and winding road”

López de Maturana, E., Pineda, S., Brand, A., Van Steen, K. & Malats, N., 01-11-2016, In : Genetic Epidemiology. 40, 7, p. 558-569 12 p.

Research output: Contribution to journalArticle

Epidemiologic Studies
Biological Phenomena
Precision Medicine
Primary Prevention
Secondary Prevention
2015
11 Citations (Scopus)

Available tools to facilitate early patient access to medicines in the EU and the USA: Analysis of conditional approvals and the implications for personalized medicine

Leyens, L., Richer, É., Melien, Ø., Ballensiefen, W. & Brand, A., 08-10-2015, In : Public Health Genomics. 18, 5, p. 249-259 11 p.

Research output: Contribution to journalArticle

Precision Medicine
Human Body
Consumer Product Safety
Phase II Clinical Trials
Microbiota
5 Citations (Scopus)

Establishing the Evidence Bar for Molecular Diagnostics in Personalised Cancer Care

Schneider, D., Bianchini, G., Horgan, D., Michiels, S., Witjes, W., Hills, R., Plun-Favreau, J., Brand, A. & Lawler, M., 01-12-2015, In : Public Health Genomics. 18, 6, p. 349-358 10 p.

Research output: Contribution to journalArticle

Molecular Pathology
Biomarkers
Neoplasms
Precision Medicine
Biological Therapy
3 Citations (Scopus)

Getting Personal: Accelerating Personalised and Precision Medicine Integration into Clinical Cancer Research and Care in Clinical Trials

Horgan, D., Lawler, M. & Brand, A., 01-12-2015, In : Public Health Genomics. 18, 6, p. 325-328 4 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population

Fernandes, R. C., Hasan, M., Gupta, H., Geetha, K., Rai, P. S., Hande, M. H., D’Souza, S. C., Adhikari, P., Brand, A. & Satyamoorthy, K., 23-06-2015, In : Molecular Genetics and Genomics. 290, 3, p. 1155-1168 14 p.

Research output: Contribution to journalArticle

Plasmodium vivax
Glutathione Transferase
Catalase
Malaria
Superoxide Dismutase
10 Citations (Scopus)

Is precision medicine the route to a healthy world?

Horgan, D., Paradiso, A., McVie, G., Banks, I., Van Der Wal, T., Brand, A. & Lawler, M., 25-07-2015, In : The Lancet. 386, 9991, p. 336-337 2 p.

Research output: Contribution to journalLetter

20 Citations (Scopus)

Success stories in genomic medicine from resource-limited countries

Mitropoulos, K., Al Jaibeji, H., Forero, D. A., Laissue, P., Wonkam, A., Lopez-Correa, C., Mohamed, Z., Chantratita, W., Lee, M. T. M., Llerena, A., Brand, A., Ali, B. R. & Patrinos, G. P., 2015, In : Human Genomics. 9, 1, 11.

Research output: Contribution to journalArticle

Pharmacogenetics
Medicine
Public Health Informatics
Public Health Practice
Genomics
2014
37 Citations (Scopus)

An index of barriers for the implementation of personalised medicine and pharmacogenomics in Europe

Horgan, D., Jansen, M., Leyens, L., Lal, J. A., Sudbrak, R., Hackenitz, E., Bußhoff, U., Ballensiefen, W. & Brand, A., 25-12-2014, In : Public Health Genomics. 17, p. 287-298 12 p.

Research output: Contribution to journalArticle

Precision Medicine
Pharmacogenetics
Delivery of Health Care
Needs Assessment
Policy Making
14 Citations (Scopus)

Bridging genomics research between developed and developing countries: The Genomic Medicine Alliance

Cooper, D. N., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Michael Lee, M. T., MacEk, M., Al-Mulla, F., Prainsack, B., Squassina, A., Vayena, E., Vozikis, A., Williams, M. S. & Patrinos, G. P., 01-09-2014, In : Personalized Medicine. 11, 7, p. 615-623 9 p.

Research output: Contribution to journalArticle

Genomics
Developed Countries
Developing Countries
Medicine
Research
1 Citation (Scopus)

European data-driven economy: A lighthouse initiative on Personalised Medicine

Horgan, D., Romão, M., Torbett, R. & Brand, A., 01-12-2014, In : Health Policy and Technology. 3, 4, p. 226-233 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genetic similarities between tobacco use disorder and related comorbidities: An exploratory study

de Viron, S., Morré, S. A., Van Oyen, H., Brand, A. & Ouburg, S., 24-07-2014, In : BMC Medical Genetics. 15, 1, 85.

Research output: Contribution to journalArticle

Tobacco Use Disorder
Comorbidity
Malignant Hypertension
Genes
Tobacco Use
1 Citation (Scopus)

Genotype-based prevention of psychosis onset and schizophrenia: A personalized approach in a target population

Taneri, B., Hocaoglu, M. B., Brand, A. & Van Os, J., 2014, In : Personalized Medicine. 11, 2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Health Services Needs and Demand
Psychotic Disorders
Schizophrenia
Genotype
Gene-Environment Interaction
59 Citations (Scopus)

Health data cooperatives - Citizen empowerment

Hafen, E., Kossmann, D. & Brand, A., 2014, In : Methods of Information in Medicine. 53, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

Health
Precision Medicine
Insurance Benefits
Power (Psychology)
Research
3 Citations (Scopus)

Public health genomics joins forces with the genomic medicine alliance

Patrinos, G. P. & Brand, A., 2014, In : Public Health Genomics. 17, 3, p. 125-126 2 p.

Research output: Contribution to journalEditorial

7 Citations (Scopus)

RARE-Bestpractices: A platform for sharing best practices for the management of rare diseases

Taruscio, D., Morciano, C., Laricchiuta, P., Mincarone, P., Palazzo, F., Leo, C. G., Sabina, S., Guarino, R., Auld, J., Sejersen, T., Gavhed, D., Ritchie, K., Hilton-Boon, M., Manson, J., Kanavos, P. G., Tordrup, D., Tzouma, V., Le Cam, Y., Senecat, J., Filippini, G. & 25 others, Minozzi, S., Del Giovane, C., Schünemann, H., Meerpohl, J. J., Prediger, B., Schell, L., Stefanov, R., Iskrov, G., Miteva-Katrandzhieva, T., Serrano-Aguilar, P., Perestelo-Perez, L., Trujillo-Martín, M. M., Pérez-Ramos, J., Rivero-Santana, A., Brand, A., Van Kranen, H., Bushby, K., Atalaia, A., Ramet, J., Siderius, L., Posada, M., Abaitua-Borda, I., Ferreira, V. A., Hens-Pérez, M. & Manzanares, F. J., 11-11-2014, In : Orphanet Journal of Rare Diseases. 9, 1, O14.

Research output: Contribution to journalArticle

Social confounders of vaccine response

Ling, M. L., Brand, A. & Ambrosino, E., 23-10-2014, Making Global Health Care Innovation Work: Standardization and Localization. Palgrave Macmillan Ltd., p. 140-157 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

The overarching framework of translation and integration into healthcare: A case for the LAL model

Lal, J. A., Morré, S. A. & Brand, A., 01-2014, In : Personalized Medicine. 11, 1, p. 41-62 22 p.

Research output: Contribution to journalArticle

Learning
Delivery of Health Care
Health Impact Assessment
Technology Transfer
Biomedical Technology Assessment

The translation of nutri-epigenetics into public health policy: The case of folic acid supplementation

Verhagen, M. M. C., Brand, A. & Ambrosino, E., 23-10-2014, Making Global Health Care Innovation Work: Standardization and Localization. Palgrave Macmillan Ltd., p. 122-138 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Whole genome prediction of bladder cancer risk with the bayesian LASSO

De Maturana, E. L., Chanok, S. J., Picornell, A. C., Rothman, N., Herranz, J., Calle, M. L., García-Closas, M., Marenne, G., Brand, A., Tardón, A., Carrato, A., Silverman, D. T., Kogevinas, M., Gianola, D., Real, F. X. & Malats, N., 2014, In : Genetic Epidemiology. 38, 5, p. 467-476 10 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Urinary Bladder
Aptitude
Genome
Carcinoma
8 Citations (Scopus)

Working towards personalization in medicine: Main obstacles to reaching this vision from today's perspective

Leyens, L., Horgan, D., Lal, J. A., Steinhausen, K., Satyamoorthy, K. & Brand, A., 01-09-2014, In : Personalized Medicine. 11, 7, p. 641-649 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Medicine
Delivery of Health Care
Technology
Research
2013
15 Citations (Scopus)

Chlamydia trachomatis infections and subfertility: Opportunities to translate host pathogen genomic data into public health

Lal, J. A., Malogajski, J., Verweij, S. P., De Boer, P., Ambrosino, E., Brand, A., Ouburg, S. & Morré, S. A., 03-2013, In : Public Health Genomics. 16, 1-2, p. 50-61 12 p.

Research output: Contribution to journalArticle

Chlamydia Infections
Chlamydia trachomatis
Genetic Markers
Infertility
Public Health
4 Citations (Scopus)

Communicating genetics and smoking through social media: Are we there yet?

Viron, S. D., Suggs, S. L., Brand, A. & Oyen, H. V., 09-2013, In : Journal of Medical Internet Research. 15, 9, e198.

Research output: Contribution to journalArticle

Social Media
Smoking
Publications
Databases
Health
2 Citations (Scopus)

Concepts for the translation of genome-based innovations into public health: A comprehensive overview

Syurina, E. V., Schulte In Den Bäumen, T., Brand, A., Ambrosino, E. & Feron, F. J. M., 2013, In : Personalized Medicine. 10, 2, p. 163-176 14 p.

Research output: Contribution to journalReview article

Public Health
Genome
Public Policy
Health Policy
Administrative Personnel
5 Citations (Scopus)

Environmental and genomic factors as well as interventions influencing smoking cessation: A systematic review of reviews and a proposed working model

De Viron, S., Malats, N., Van Der Heyden, J., Van Oyen, H. & Brand, A., 08-2013, In : Public Health Genomics. 16, 4, p. 159-173 15 p.

Research output: Contribution to journalReview article

Metagenomics
Smoking Cessation
Smoking
Gene-Environment Interaction
PubMed