Department of Radiation Biology and Toxicology, Manipal School of Life Sciences, Manipal

  • India

Research Output 1992 2019

  • 1982 Citations
  • 25 h-Index
  • 106 Article
  • 18 Conference contribution
  • 2 Comment/debate
  • 1 Review article
2019

Action of He-Ne laser on wounded human skin fibroblast cells

Prabhu, V., Rao, B. S. S. & Mahato, K. K., 01-01-2019, Medical Laser Applications and Laser-Tissue Interactions IX. Lilge, L. D. & Philipp, C. M. (eds.). SPIE, 110790T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

fibroblasts
Fibroblasts
Skin
Lasers
Cells
1 Citation (Scopus)

Chemical, cytotoxic and genotoxic analysis of etidronate in sodium hypochlorite solution

Ballal, N. V., Das, S., Rao, B. S. S., Zehnder, M. & Mohn, D., 01-08-2019, In : International Endodontic Journal. 52, 8, p. 1228-1234 7 p.

Research output: Contribution to journalArticle

Etidronic Acid
Sodium Hypochlorite
Micronucleus Tests
Poisons
Dental Pulp Cavity
1 Citation (Scopus)

Neuroprotective role of naringenin against methylmercury induced cognitive impairment and mitochondrial damage in a mouse model

Krishna Chandran, A. M., Christina, H., Das, S., Mumbrekar, K. D. & Satish Rao, B. S., 01-10-2019, In : Environmental Toxicology and Pharmacology. 71, 103224.

Research output: Contribution to journalArticle

Cell death
Cell Death
Seafood
Mitochondria
Citrus

Whole mitochondria genome mutational spectrum in occupationally exposed lead subjects

Mani, M. S., Chakrabarty, S., Mallya, S. P., Kabekkodu, S. P., Jayaram, P., Varghese, V. K., Dsouza, H. S. & Satyamoorthy, K., 01-09-2019, In : Mitochondrion. 48, p. 60-66 7 p.

Research output: Contribution to journalArticle

Mitochondria
Genome
DNA
Mutation
Gene Order
2018
1 Citation (Scopus)

Interrogation of an autofluorescence-based method for protein fingerprinting

Siddaramaiah, M., Rao, B. S. S., Joshi, M. B., Datta, A., Sandya, S., Vishnumurthy, V., Chandra, S., Nayak, S. G., Satyamoorthy, K. & Mahato, K. K., 01-08-2018, In : Journal of Biophotonics. 11, 8, e201700393.

Research output: Contribution to journalArticle

Peptide Mapping
interrogation
proteins
Proteins
electrophoresis
6 Citations (Scopus)

Laser-induced autofluorescence-based objective evaluation of burn tissue repair in mice

Rathnakar, B., Rao, B. S. S., Prabhu, V., Chandra, S. & Mahato, K. K., 01-05-2018, In : Lasers in Medical Science. p. 1-9 9 p.

Research output: Contribution to journalArticle

Lasers
Collagen
Fluorescence
Observation
Biopsy
3 Citations (Scopus)

Modifying effects of δ-Aminolevulinate dehydratase polymorphism on blood lead levels and ALAD activity

Mani, M. S., Kunnathully, V., Rao, C., Kabekkodu, S. P., Joshi, M. B. & D'Souza, H. S., 01-10-2018, In : Toxicology Letters. 295, p. 351-356 6 p.

Research output: Contribution to journalArticle

Hydro-Lyases
Polymorphism
Blood
Lead
Porphobilinogen Synthase
1 Citation (Scopus)
Triage
Phosphoric Monoester Hydrolases
phosphatase
Microscopy
inhibitor

Probing endogenous collagen by laser-induced autofluorescence in burn wound biopsies: A pilot study

Prabhu, V., Acharya, A., Satish Rao, B. S., Rathnakar, B., Kumar, P., Guddattu, V. & Mahato, K. K., 01-09-2018, In : Journal of Biophotonics. 11, 9, e201700394.

Research output: Contribution to journalArticle

Biopsy
collagens
Collagen
Granulation Tissue
Lasers

Systemic Toxicity and Teratogenicity of Copper Oxide Nanoparticles and Copper Sulfate

Kadammattil, A. V., Sajankila, S. P., Prabhu, S., Rao, B. N. & Rao, B. S. S., 01-04-2018, In : Journal of Nanoscience and Nanotechnology. 18, 4, p. 2394-2404 11 p.

Research output: Contribution to journalArticle

Copper Sulfate
Copper oxides
copper oxides
toxicity
Nanoparticles
2017
5 Citations (Scopus)

A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: Tumor-specific homing directed by nestin

Prabhu, S., Goda, J. S., Mutalik, S., Mohanty, B. S., Chaudhari, P., Rai, S., Udupa, N. & Rao, B. S. S., 14-08-2017, In : Nanoscale. 9, 30, p. 10919-10932 14 p.

Research output: Contribution to journalArticle

temozolomide
Nestin
Heterografts
Tumors
Nanocomposites
Plasma Gases
Durapatite
Atmosphere
Blood Platelets
Cell Survival
1 Citation (Scopus)
Thiadiazoles
Cytotoxicity
Adenocarcinoma
Breast
Molecular Docking Simulation
3 Citations (Scopus)
Nanocomposites
Heterografts
Toxicity
Cells
Breast Neoplasms
4 Citations (Scopus)

Genetic Variants in CD44 and MAT1A Confer Susceptibility to Acute Skin Reaction in Breast Cancer Patients Undergoing Radiation Therapy

Mumbrekar, K. D., Bola Sadashiva, S. R., Kabekkodu, S. P., Fernandes, D. J., Vadhiraja, B. M., Suga, T., Shoji, Y., Nakayama, F., Imai, T. & Satyamoorthy, K., 01-01-2017, In : International Journal of Radiation Oncology Biology Physics. 97, 1, p. 118-127 10 p.

Research output: Contribution to journalArticle

breast
radiation therapy
genes
Radiotherapy
cancer

Genotype-phenotype association of TGF-β1 and GST with chemo-radiotherapy induced toxicity

Goutham, H. V., Mumbrekar, K. D., Hitendra, N., Vadhiraja, B. M., Fernandes, D. J. & Satish Rao, B. S., 01-01-2017, In : International Journal of Radiation Research. 15, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Genetic Association Studies
Transforming Growth Factors
Glutathione Transferase
Radiotherapy
Stomatitis
4 Citations (Scopus)

Harmonization of Mangiferin on methylmercury engendered mitochondrial dysfunction

Das, S., Paul, A., Mumbrekar, K. D. & Rao, S. B. S., 01-02-2017, In : Environmental Toxicology. 32, 2, p. 630-644 15 p.

Research output: Contribution to journalArticle

methylmercury
antioxidant
viability
homeostasis
iodide
2 Citations (Scopus)
Denaturation
biopolymer denaturation
ureas
Urea
proteins
2 Citations (Scopus)
Hep G2 Cells
Cadmium
Cadmium Chloride
Oxidation-Reduction
Homeostasis

Photo-bio modulatory response of platelets to low power laser - A pilot study

Rathnakar, B., Bhyravbhatla, N., Chandra, S., Rao, B. S. S. & Mahato, K. K., 01-01-2017, Frontiers in Optics, FiO 2017. OSA - The Optical Society, Vol. Part F66-FiO 2017.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Platelets
Lasers
Mitochondria
Flow cytometry
Hemostatics
2016
Lymphocytes
Radiation Tolerance
Polymorphism
DNA Repair
Emotions

Fluorescence based assessment of SDS induced hydrophobic collapse in globular proteins

Manjunath, S., Makani, V. K. K., Satyamoorthy, K., Rao, B. S. S., Bhat, G., Kanth, A. B. & Mahato, K. K., 2016, Biophysics, Biology, and Biophotonics: The Crossroads. SPIE, Vol. 9719. 97190A

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorescence
proteins
Proteins
albumins
serums
11 Citations (Scopus)
Poisons
methylmercury
phenolic compound
Neuroblastoma
Toxicity
2 Citations (Scopus)

Photoacoustic spectroscopy based investigatory approach to discriminate breast cancer from normal: A pilot study

Priya, M., Rao, B. S. S., Chandra, S., Ray, S., Mathew, S., Datta, A., Nayak, S. G. & Mahato, K. K., 2016, Photonic Therapeutics and Diagnostics XII. SPIE, Vol. 9689. 968943

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic spectroscopy
Passive Cutaneous Anaphylaxis
photoacoustic spectroscopy
breast
Area Under Curve
13 Citations (Scopus)

Photo-biomodulatory response of low-power laser irradiation on burn tissue repair in mice

Rathnakar, B., Rao, B. S. S., Prabhu, V., Chandra, S., Rai, S., Rao, A. C. K., Sharma, M., Gupta, P. K. & Mahato, K. K., 01-12-2016, In : Lasers in Medical Science. 31, 9, p. 1741-1750 10 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Lasers
Povidone-Iodine
Wound Healing
Low-Level Light Therapy
11 Citations (Scopus)

Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals

Mumbrekar, K. D., Goutham, H. V., Vadhiraja, B. M. & Bola Sadashiva, S. R., 01-04-2016, In : DNA Repair. 40, p. 27-34 8 p.

Research output: Contribution to journalArticle

Lymphocytes
Radiation Tolerance
Polymorphism
Repair
Genes
5 Citations (Scopus)
Psidium
Wistar Rats
Oxidative Stress
X-Rays
Apoptosis
1 Citation (Scopus)

Regulation of cellular marker modulated upon irradiation of low power laser light in burn injured mice

Rathnakar, B., Prabhu, V., Rao, B. S. S., Chandra, S., Rai, S. & Mahato, K. K., 2016, SPIE BioPhotonics Australasia. SPIE, Vol. 10013. 100132Z

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Irradiation
markers
mice
Mouse
Tissue
11 Citations (Scopus)

Systematic Development and Validation of a Thin-Layer Densitometric Bioanalytical Method for Estimation of Mangiferin Employing Analytical Quality by Design (AQbD) Approach

Khurana, R. K., Rao, S., Beg, S., Katare, O. P. & Singh, B., 01-05-2016, In : Journal of Chromatographic Science. 54, 5, p. 829-841 13 p.

Research output: Contribution to journalArticle

formic acid
Recovery
Acetic Acid
Screening
mangiferin
2015

Autofluorescence based visualization of proteins from unstained native-PAGE

Manjunath, S., Rao, B. S. S., Satyamoorthy, K. & Mahato, K. K., 2015, Single Molecule Spectroscopy and Superresolution Imaging VIII. SPIE, Vol. 9331. 933113

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Native Polyacrylamide Gel Electrophoresis
Acrylamide
electrophoresis
Electrophoresis
Gels
8 Citations (Scopus)
Mercaptoethanol
Protons
electron transfer
tyrosine
tryptophan
1 Citation (Scopus)

Low power laser irradiation stimulates cell proliferation via proliferating cell nuclear antigen and Ki-67 expression during tissue repair

Prabhu, V., Rao, B. S. S. & Mahato, K. K., 2015, Mechanisms for Low-Light Therapy X. SPIE, Vol. 9309. 93090Q

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proliferating Cell Nuclear Antigen
Cell proliferation
antigens
Laser beam effects
Antigens
2 Citations (Scopus)

Monitoring breast tumor progression by photoacoustic measurements: A xenograft mice model study

Priya, M., Satish Rao, B. S., Chandra, S., Datta, A., Nayak, S. G. & Mahato, K. K., 01-10-2015, In : Journal of Biomedical Optics. 20, 10, 105002.

Research output: Contribution to journalArticle

Photoacoustic effect
Heterografts
progressions
breast
mice
11 Citations (Scopus)
Drug Delivery
Toxicity
Drug delivery
Iron oxides
iron oxides
1 Citation (Scopus)

Photoacoustic spectroscopy based evaluation of breast cancer condition

Priya, M., Chandra, S., Rao, B. S. S., Ray, S., Shetty, P., Mathew, S. & Mahato, K. K., 2015, Photonic Therapeutics and Diagnostics XI. SPIE, Vol. 9303. 93032L

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic spectroscopy
photoacoustic spectroscopy
breast
Tumors
Spectrum Analysis

Predictive potential of photoacoustic spectroscopy in breast tumor detection based on xenograft serum profiles

Priya, M., Chandra, S., Rao, B. S. S., Ray, S. & Mahato, K. K., 2015, Photonic Therapeutics and Diagnostics XI. SPIE, Vol. 9303. 93032V

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic spectroscopy
photoacoustic spectroscopy
Photoacoustic effect
Heterografts
breast
1 Citation (Scopus)
Cricetulus
Ionizing Radiation
Radio
Fibroblasts
Radiation
4 Citations (Scopus)

Radiosensitizing potential of Plumbagin in B16F1 melanoma tumor cells through mitochondrial mediated programmed cell death

Satish Rao, B. S., Sunil Kumar, M. R., Das, S., Aithal, K. & Udupa, N., 01-11-2015, In : Journal of Applied Biomedicine. 13, 4, p. 279-288 10 p.

Research output: Contribution to journalArticle

plumbagin
Cell death
melanoma
Tumors
Melanoma
12 Citations (Scopus)

Thymol, a monoterpene phenolic derivative of cymene, abrogates mercury-induced oxidative stress resultant cytotoxicity and genotoxicity in hepatocarcinoma cells

Shettigar, N. B., Das, S., Rao, N. B. & Rao, S. B. S., 08-07-2015, In : Environmental Toxicology. 30, 8, p. 968-980 13 p.

Research output: Contribution to journalArticle

Thymol
Mercuric Chloride
Monoterpenes
Oxidative stress
monoterpene
2014
2 Citations (Scopus)

Alterations in cell migration and cell viability of wounded human skin fibroblasts following visible red light exposure

Prabhu, V., Rao, B. S. S. & Mahato, K. K., 2014, Mechanisms for Low-Light Therapy IX. SPIE, Vol. 8932. 89320C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

fibroblasts
Fibroblasts
viability
Cell Movement
Cell Survival

Efficacy of multiple exposure with low level He-Ne laser dose on acute wound healing: A pre-clinical study

Prabhu, V., Rao, B. S. S. & Mahato, K. K., 2014, Mechanisms for Low-Light Therapy IX. SPIE, Vol. 8932. 89320T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

wound healing
Wound Healing
Lasers
dosage
healing
17 Citations (Scopus)

Falls in Indian older adults: A barrier to active ageing

Dsouza, S. A., Rajashekar, B., Dsouza, H. S. & Kumar, K. B., 2014, In : Asian Journal of Gerontology and Geriatrics. 9, 1, p. 33-40 8 p.

Research output: Contribution to journalReview article

India
Wounds and Injuries
Economics
Delivery of Health Care
Information Storage and Retrieval
22 Citations (Scopus)

Influence of double-strand break repair on radiation therapy-induced acute skin reactions in breast cancer patients

Mumbrekar, K. D., Fernandes, D. J., Goutham, H. V., Sharan, K., Vadhiraja, B. M., Satyamoorthy, K. & Bola Sadashiva, S. R., 01-03-2014, In : International Journal of Radiation Oncology Biology Physics. 88, 3, p. 671-676 6 p.

Research output: Contribution to journalArticle

breast
strands
radiation therapy
Radiotherapy
cancer
1 Citation (Scopus)

Nature of autofluorescence in human serum albumin under its native, unfolding and digested forms

Manjunath, S., Rao, B. S. S., Satyamoorthy, K. & Mahato, K. K., 2014, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII. SPIE, Vol. 8935. 893520

Research output: Chapter in Book/Report/Conference proceedingConference contribution

tryptophan
albumins
tyrosine
Urea
Serum Albumin
19 Citations (Scopus)

Objective assessment of endogenous collagen in vivo during tissue repair by laser induced fluorescence

Prabhu, V., Rao, S. B. S., Fernandes, E. M., Rao, A. C. K., Prasad, K. & Mahato, K. K., 29-05-2014, In : PLoS One. 9, 5, e98609.

Research output: Contribution to journalArticle

tissue repair
lasers
collagen
Lasers
Repair
3 Citations (Scopus)

Photoacoustic spectroscopy in the monitoring of breast tumor development: A pre-clinical study

Priya, M., Rao, B. S. S., Ray, S. & Mahato, K. K., 2014, Photons Plus Ultrasound: Imaging and Sensing 2014. SPIE, Vol. 8943. 894347

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic spectroscopy
photoacoustic spectroscopy
breast
Tumors
Spectrum Analysis

Photobiomodulatory effects of he- ne laser on wounded human skin fibroblasts

Prabhu, V., Rao, B. S. S. & Mahato, K. K., 21-07-2014, International Conference on Fibre Optics and Photonics, Photonics 2016. OSA - The Optical Society

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fibroblasts
Skin
Cells
Monolayers
Lasers
25 Citations (Scopus)

Polymorphisms in radio-responsive genes and its association with acute toxicity among head and neck cancer patients

Venkatesh, G. H., Manjunath, V. B., Mumbrekar, K. D., Negi, H., Fernandes, D. J., Sharan, K., Banerjee, S. & Sadashiva, S. R. B., 04-03-2014, In : PLoS One. 9, 3, e89079.

Research output: Contribution to journalArticle

Radiotherapy
radiotherapy
acute toxicity
Head and Neck Neoplasms
Polymorphism
6 Citations (Scopus)
Photoacoustic effect
Pulsed lasers
Tryptophan
tryptophan
pulsed lasers

Prognostic prospective of laser induced fluorescence as an objective tool to evaluate collagen deposition in thermal wounds: An ex vivo study

Prabhu, V., Acharya, A., Rao, S. B. S., Kumar, P., Sharan, A. & Mahato, K. K., 2014, Photonic Therapeutics and Diagnostics X. SPIE, Vol. 8926. 892608

Research output: Chapter in Book/Report/Conference proceedingConference contribution

collagens
Granulation
Granulation Tissue
Collagen
laser induced fluorescence