• 766 Citations
  • 16 h-Index
20072020
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Research Output 2007 2020

  • 766 Citations
  • 16 h-Index
  • 64 Article
  • 3 Chapter
  • 1 Comment/debate
  • 1 Review article
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Article
2020
Mental Competency
Oocytes
Spermatozoa
Tuberculosis
Ethambutol
2019
2 Citations (Scopus)

Cyclodextrins as Carriers in Targeted Delivery of Therapeutic Agents: Focused Review on Traditional and Inimitable Applications

Raut, S. Y., Manne, A. S. N., Kalthur, G., Jain, S. & Mutalik, S., 01-01-2019, In : Current Pharmaceutical Design. 25, 4, p. 444-454 11 p.

Research output: Contribution to journalArticle

Cyclodextrins
Pharmaceutical Preparations
Drug Delivery Systems
Therapeutics
Drug Carriers
5 Citations (Scopus)
Nanocomposites
Diclofenac
Microspheres
Polymers
Pharmaceutical Preparations
1 Citation (Scopus)

Sperm-mediated DNA lesions alter metabolite levels in spent embryo culture medium

Souza, F. D., Asampille, G., Uppangala, S., Kalthur, G., Atreya, H. S. & Adiga, S. K., 01-01-2019, In : Reproduction, Fertility and Development. 31, 3, p. 443-450 8 p.

Research output: Contribution to journalArticle

embryo culture
Culture Media
Spermatozoa
embryo (animal)
Embryonic Structures

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Biotin
Embryonic Development
Spermatozoa
Pentoxifylline
Fertilization
2018
2 Citations (Scopus)

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

D’Souza, F., Uppangala, S., Asampille, G., Salian, S. R., Kalthur, G., Talevi, R., Atreya, H. S. & Adiga, S. K., 01-12-2018, In : Scientific Reports. 8, 1, 17025.

Research output: Contribution to journalArticle

Blastocyst
Culture Media
Embryonic Structures
Pyruvic Acid
Injections
3 Citations (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

Sunscreening Agents
Nanoparticles
Skin
In Vitro Techniques
naringenin
2017
1 Citation (Scopus)

Epigenetic changes in preimplantation embryos subjected to laser manipulation

Honguntikar, S. D., Salian, S. R., D’Souza, F., Uppangala, S., Kalthur, G. & Adiga, S. K., 01-12-2017, In : Lasers in Medical Science. 32, 9, p. 2081-2087 7 p.

Research output: Contribution to journalArticle

Blastocyst
Epigenomics
Lasers
Embryonic Structures
Transferases
1 Citation (Scopus)
Haploidy
Ammonia
Embryonic Structures
Blastocyst
Parthenogenesis
5 Citations (Scopus)
Propolis
Mitomycin
DNA Damage
Antioxidants
Fertility Preservation
24 Citations (Scopus)

Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen

Manikkath, J., Hegde, A. R., Kalthur, G., Parekh, H. S. & Mutalik, S., 15-04-2017, In : International Journal of Pharmaceutics. 521, 1-2, p. 110-119 10 p.

Research output: Contribution to journalArticle

Ketoprofen
Dendrimers
Peptides
Pharmaceutical Preparations
Arginine
2 Citations (Scopus)
Inositol
Liposomes
Glycerol
Oocytes
Blastocyst
32 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Antioxidants
Radiation
Skin
Differential Scanning Calorimetry
1 Citation (Scopus)

Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 28-11-2017, (Accepted/In press) In : Zygote. p. 1-14 14 p.

Research output: Contribution to journalArticle

Haploidy
Spermatozoa
Oocytes
Status Epilepticus
Zygote
11 Citations (Scopus)

Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

Research output: Contribution to journalArticle

Zinc Oxide
Cryopreservation
Nanoparticles
Spermatozoa
Fluorescence microscopy
2016
18 Citations (Scopus)

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

Mutalik, S., Suthar, N. A., Managuli, R. S., Shetty, P. K., Avadhani, K., Kalthur, G., Kulkarni, R. V. & Thomas, R., 01-05-2016, In : International Journal of Biological Macromolecules. 86, p. 709-720 12 p.

Research output: Contribution to journalArticle

Curcumin
Nanoparticles
Copolymers
Inflammatory Bowel Diseases
Rats
13 Citations (Scopus)
Octamer Transcription Factors
Superovulation
superovulation
Organelles
Oocytes
3 Citations (Scopus)

Ethambutol induces testicular damage and decreases the sperm functional competence in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Prabhu, A. D., Khandige, N., Kalthur, S. G., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Environmental Toxicology and Pharmacology. 47, p. 28-37 10 p.

Research output: Contribution to journalArticle

Ethambutol
Mental Competency
Spermatozoa
Sperm Head
Sperm Count
11 Citations (Scopus)

Ethanolic extract of Moringa oleifera Lam. leaves protect the pre-pubertal spermatogonial cells from cyclophosphamide-induced damage

Nayak, G., Honguntikar, S. D., Kalthur, S. G., D'Souza, A. S., Mutalik, S., Setty, M. M., Kalyankumar, R., Krishnamurthy, H., Kalthur, G. & Adiga, S. K., 22-04-2016, In : Journal of Ethnopharmacology. 182, p. 101-109 9 p.

Research output: Contribution to journalArticle

Moringa oleifera
Germ Cells
Cyclophosphamide
DNA Damage
Body Weight
4 Citations (Scopus)
Plasma stability
Lymphocytes
Ionizing radiation
Ionizing Radiation
Health care
8 Citations (Scopus)

Influence of sperm DNA damage on human preimplantation embryo metabolism

Uppangala, S., Pudakalakatti, S., D'souza, F., Salian, S. R., Kalthur, G., Kumar, P., Atreya, H. & Adiga, S. K., 01-09-2016, In : Reproductive biology. 16, 3, p. 234-241 8 p.

Research output: Contribution to journalArticle

Blastocyst
DNA damage
DNA Damage
Spermatozoa
embryo (animal)
5 Citations (Scopus)

Laser assisted zona hatching does not lead to immediate impairment in human embryo quality and metabolism

Uppangala, S., D’Souza, F., Pudakalakatti, S., Atreya, H. S., Raval, K., Kalthur, G. & Adiga, S. K., 01-11-2016, In : Systems Biology in Reproductive Medicine. 62, 6, p. 396-403 8 p.

Research output: Contribution to journalArticle

Herpes Zoster
Lasers
Embryonic Structures
Magnetic Resonance Spectroscopy
Assisted Reproductive Techniques
5 Citations (Scopus)

Mitigating effect of Indian propolis against mitomycin C induced bone marrow toxicity

Kumari, S., Naik, P., Vishma, B. L., Salian, S. R., Devkar, R. A., Khan, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Cytotechnology. 68, 5, p. 1789-1800 12 p.

Research output: Contribution to journalArticle

Propolis
Mitomycin
Lipids
Toxicity
Assays
19 Citations (Scopus)

Nano-transfersomal formulations for transdermal delivery of asenapine maleate: in vitro and in vivo performance evaluations

Shreya, A. B., Managuli, R. S., Menon, J., Kondapalli, L., Hegde, A. R., Avadhani, K., Shetty, P. K., Amirthalingam, M., Kalthur, G. & Mutalik, S., 02-07-2016, In : Journal of Liposome Research. 26, 3, p. 221-232 12 p.

Research output: Contribution to journalArticle

Biological Availability
Skin
Deoxycholic Acid
Phosphatidylcholines
Ethanol
14 Citations (Scopus)

Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract

Nayak, G., Vadinkar, A., Nair, S., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Shetty, M. M., Kalthur, G. & Adiga, S. K., 01-03-2016, In : Andrologia. 48, 2, p. 125-136 12 p.

Research output: Contribution to journalArticle

Moringa oleifera
Cyclophosphamide
Spermatozoa
Injections
DNA Damage
3 Citations (Scopus)

Sperm chromatin immaturity observed in short abstinence ejaculates affects DNA integrity and longevity in vitro

Uppangala, S., Mathai, S. E., Salian, S. R., Kumar, D., Singh, V. J., D'Souza, F., Kalthur, G., Kamath, A. & Adiga, S. K., 01-04-2016, In : PLoS One. 11, 4, e0152942.

Research output: Contribution to journalArticle

Chromatin
chromatin
Spermatozoa
spermatozoa
DNA
1 Citation (Scopus)

Synthesis, anti-proliferative and genotoxicity studies of 6-chloro-5-(2-substituted-ethyl)-1,3-dihydro-2 H-indol-2-ones and 6-chloro-5-(2-chloroethyl)-3-(alkyl/ary-2-ylidene)indolin-2-ones

Meti, G. Y., Kamble, A. A., Kamble, R. R., Somagond, S. M., Devarajegowda, H. C., Kumari, S., Kalthur, G. & Adiga, S. K., 04-10-2016, In : European Journal of Medicinal Chemistry. 121, p. 221-231 11 p.

Research output: Contribution to journalArticle

Growth
Screening
indolin-2-one
In Vitro Techniques
2-oxindole
5 Citations (Scopus)

Unraveling the association between genetic integrity and metabolic activity in pre-implantation stage embryos

D'Souza, F., Pudakalakatti, S. M., Uppangala, S., Honguntikar, S., Salian, S. R., Kalthur, G., Pasricha, R., Appajigowda, D., Atreya, H. S. & Adiga, S. K., 17-11-2016, In : Scientific Reports. 6, 37291.

Research output: Contribution to journalArticle

metabolites
biomarkers
thymine
DNA
isoleucine
2015
27 Citations (Scopus)

Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In : International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

Research output: Contribution to journalArticle

Sun hoods
Sunscreening Agents
Radiation protection
Radiation Protection
Antioxidants
1 Citation (Scopus)

In situ viability detection assays induce heat-shock protein 70 expression in spermatozoa without affecting the chromatin integrity

Asokan, Y., Honguntikar, S. D., Uppangala, S., Salian, S. R., Kumar, D., Kalthur, G. & Adiga, S. K., 01-10-2015, In : Andrologia. 47, 8, p. 958-965 8 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Chromatin
Spermatozoa
Pentoxifylline
Sperm Head
2 Citations (Scopus)

In vitro matured oocytes are more susceptible than in vivo matured oocytes to mock ICSI induced functional and genetic changes

Uppangala, S., Dhiman, S., Salian, S. R., Singh, V. J., Kalthur, G. & Adiga, S. K., 18-03-2015, In : PLoS One. 10, 3, e0119735.

Research output: Contribution to journalArticle

Phosphorylation
Intracytoplasmic Sperm Injections
Oocytes
Reactive Oxygen Species
oocytes
1 Citation (Scopus)

Oocytes recovered after ovarian tissue slow freezing have impaired H2AX phosphorylation and functional competence

Sudhakaran, S., Uppangala, S., Salian, S. R., Honguntikar, S. D., Nair, R., Kalthur, G. & Adiga, S. K., 2015, In : Reproduction, Fertility and Development. 27, 8, p. 1242-1248 7 p.

Research output: Contribution to journalArticle

Mental Competency
Freezing
Oocytes
phosphorylation
freezing
19 Citations (Scopus)

Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells

Khaw, A. K., Sameni, S., Venkatesan, S., Kalthur, G. & Hande, M. P., 01-11-2015, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 793, p. 86-95 10 p.

Research output: Contribution to journalArticle

Telomere
Brain Neoplasms
DNA Damage
Cell Death
Telomerase
2014
13 Citations (Scopus)

Association between sperm DNA integrity and seminal plasma antioxidant levels in health workers occupationally exposed to ionizing radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Jain, N., Krishnamurthy, H., Kumar, P. & Adiga, S. K., 2014, In : Environmental Research. 132, p. 297-304 8 p.

Research output: Contribution to journalArticle

health worker
Ionizing radiation
Ionizing Radiation
Semen
sperm
6 Citations (Scopus)

Laser-assisted hatching of cleavage-stage embryos impairs developmental potential and increases DNA damage in blastocysts

Honguntikar, S. D., Uppangala, S., Salian, S. R., Kalthur, G., Kumar, P. & Adiga, S. K., 2014, In : Lasers in Medical Science. 30, 1, p. 95-101 7 p.

Research output: Contribution to journalArticle

Blastocyst
DNA Damage
Lasers
Embryonic Structures
Cell Count
16 Citations (Scopus)

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

Nair, R., Singh, V. J., Salian, S. R., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Kalthur, G. & Adiga, S. K., 2014, In : Toxicology and Applied Pharmacology. 279, 3, p. 338-350 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Ovarian tissue vitrification is more efficient than slow freezing in protecting oocyte and granulosa cell DNA integrity

Mathias, F. J., D'souza, F., Uppangala, S., Salian, S. R., Kalthur, G. & Adiga, S. K., 01-12-2014, In : Systems Biology in Reproductive Medicine. 60, 6, p. 317-322 6 p.

Research output: Contribution to journalArticle

Vitrification
Granulosa Cells
Freezing
Oocytes
DNA
4 Citations (Scopus)

Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties

Castelino, P. A., Naik, P., Dasappa, J. P., Sujayraj, R. S., Sharath Chandra, K., Chaluvaiah, K., Nair, R., Sandya Kumari, M. V., Kalthur, G. & Adiga, S. K., 12-09-2014, In : European Journal of Medicinal Chemistry. 84, p. 194-199 6 p.

Research output: Contribution to journalArticle

Culicidae
Pyruvic Acid
Malaria
Ethanol
Nuclear magnetic resonance
2013
49 Citations (Scopus)

Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells

Hande, M. P., Khaw, A. K., Hande, M. P. & Kalthur, G., 06-2013, In : Journal of Cellular Biochemistry. 114, 6, p. 1257-1270 14 p.

Research output: Contribution to journalArticle

Telomere Shortening
Curcumin
Telomerase
Brain Neoplasms
Tumors
26 Citations (Scopus)

NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: A new biomarker for assessment of embryo implantation potential

Pudakalakatti, S. M., Uppangala, S., D'Souza, F., Kalthur, G., Kumar, P., Adiga, S. K. & Atreya, H. S., 01-2013, In : NMR in Biomedicine. 26, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

Assisted Reproductive Techniques
Blastocyst
Biomarkers
Pyruvic Acid
Metabolism
9 Citations (Scopus)
Herpes Zoster
DNA Fragmentation
Mental Competency
Spermatozoa
Zona Pellucida
33 Citations (Scopus)

Semen Abnormalities, Sperm DNA Damage and Global Hypermethylation in Health Workers Occupationally Exposed to Ionizing Radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Krishnamurthy, H., Jain, N., Kumar, P. & Adiga, S. K., 29-07-2013, In : PLoS One. 8, 7, e69927.

Research output: Contribution to journalArticle

Ionizing radiation
health care workers
Ionizing Radiation
Semen
ionizing radiation
7 Citations (Scopus)
DNA Damage
Spermatozoa
DNA
Fertilization
Research Design
2012
26 Citations (Scopus)

Addition of zinc to human ejaculate prior to cryopreservation prevents freeze-thaw-induced DNA damage and preserves sperm function

Kotdawala, A. P., Kumar, S., Salian, S. R., Thankachan, P., Govindraj, K., Kumar, P., Kalthur, G. & Adiga, S. K., 12-2012, In : Journal of Assisted Reproduction and Genetics. 29, 12, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

Cryopreservation
Semen
DNA Damage
Spermatozoa
Zinc
7 Citations (Scopus)
Povidone
DNA Fragmentation
Immobilization
Spermatozoa
Intracytoplasmic Sperm Injections
30 Citations (Scopus)

Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells

Khaw, A. K., Yong, J. W. Y., Kalthur, G. & Hande, M. P., 10-2012, In : Genes Chromosomes and Cancer. 51, 10, p. 961-974 14 p.

Research output: Contribution to journalArticle

Genistein
Telomerase
Brain Neoplasms
Growth
Cell Cycle Checkpoints
12 Citations (Scopus)

Germ cell abnormalities in streptozotocin induced diabetic mice do not correlate with blood glucose level

Bose, R., Adiga, S. K., D'Souza, F., Salian, S. R., Uppangala, S., Kalthur, G., Jain, N., Radhakrishnan, R. A., Bhat, N., Krishnamurthy, H. & Kumar, P., 12-2012, In : Journal of Assisted Reproduction and Genetics. 29, 12, p. 1405-1413 9 p.

Research output: Contribution to journalArticle

Streptozocin
Germ Cells
Blood Glucose
Ploidies
Spermatozoa
41 Citations (Scopus)

Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men

Varshini, J., Srinag, B. S., Kalthur, G., Krishnamurthy, H., Kumar, P., Rao, S. B. S. & Adiga, S. K., 05-2012, In : Andrologia. 44, SUPPL.1, p. 642-649 8 p.

Research output: Contribution to journalArticle

DNA Damage
Spermatozoa
Semen
Oligospermia
Varicocele
8 Citations (Scopus)

Supplementation of biotin to sperm preparation medium increases the motility and longevity in cryopreserved human spermatozoa

Kalthur, G., Salian, S. R., Keyvanifard, F., Sreedharan, S., Thomas, J. S., Kumar, P. & Adiga, S. K., 07-2012, In : Journal of Assisted Reproduction and Genetics. 29, 7, p. 631-635 5 p.

Research output: Contribution to journalArticle

Biotin
Pentoxifylline
Spermatozoa
Semen
Semen Preservation