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Research Output

  • 436 Citations
  • 12 h-Index
  • 41 Article
  • 1 Review article
2020

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

Thirupataiah, B., Reddy, G. S., Ghule, S. S., Kumar, J. S., Mounika, G., Hossain, K. A., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 04-2020, In : Bioorganic Chemistry. 97, 103691.

Research output: Contribution to journalArticle

2019

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In : European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Neprilysin, the kidney brush border neutral proteinase: a possible potential target for ischemic renal injury

Sankhe, R., Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2019, (Accepted/In press) In : Toxicology Mechanisms and Methods.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 03-10-2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In : European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 07-03-2018, (Accepted/In press) In : Metabolic Brain Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

An insight into the role of cyclooxygenase and lipooxygenase pathway in renal ischemia

Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2017, In : European Review for Medical and Pharmacological Sciences. 21, 21, p. 5017-5020 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

Basu Mallik, S., Mudgal, J., Nampoothiri, M., Hall, S., Dukie, S. A., Grant, G., Rao, C. M. & Arora, D., 06-10-2016, In : Neuroscience Letters. 632, p. 218-223 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Dose-related antihyperglycemic and hypolipidemic effects of two novel thiazolidin-4-ones in a rodent model of metabolic syndrome

Karot, S. S., Surenahalli, V. G., Kishore, A., Mudgal, J., Nandakumar, K., Chirayil, M. T., Mathew, G. & Nampurath, G. K., 01-09-2016, In : Journal of Diabetes. 8, 5, p. 629-639 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
12 Citations (Scopus)

In vitro and in vivo hepatoprotective action of L-α-phosphatidylcholine in alcohol-induced toxicity model

Raj, P. V., Mudgal, J., Reddy, N. D., Rao, C. M., Bansal, P., Rai, A. & Kumar, N., 01-11-2016, In : International Journal of Pharmaceutical Sciences Review and Research. 41, 1, p. 171-176 6 p., 33.

Research output: Contribution to journalArticle

In vitro cytotoxicity activity of chrysin, morin and resveratrol against MCF-7 breast cancer cell lines

Thomas, A., Ranadive, N., Nayak, H., Surendran, S., Nampoothiri, M., Mudgal, J. & Nayak, Y., 01-09-2016, In : Biosciences Biotechnology Research Asia. 13, 3, p. 1633-1637 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In : Frontiers in Pharmacology. 7, OCT, 381.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)
2015

Anti-tubercular activity of synthesized novel 2,5-disubstituted-1,3,4-oxadiazole derivatives

Ega, D., Attari, Z., Mudgal, J., Bairy, I., Vishnuprasad, S. & Nampurath, G. K., 2015, In : Indian Drugs. 52, 2, p. 40-44 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Durgashivaprasad, E., Attari, Z., Mudgal, J., Bairy, L. K., Vishnu Prasad, S. & Kutty Nampurath, G., 2015, In : Indian Drugs. 52, 2, p. 40-44. 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2014

Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

Durgashivaprasad, E., Mathew, G., Sebastian, S., Manohar Reddy, S. A., Mudgal, J. & Nampurath, G. K., 2014, In : Indian Journal of Pharmacology. 46, 5, p. 521-526 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In : Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
3 Citations (Scopus)
2013

Evaluation of in vitro antioxidant and in Vivo analgesic potential of Terminalia paniculata aqueous bark extract

Talwar, S., Nayak, P. G., Mudgal, J., Paul, P., Bansal, P. & Nandakumar, K., 2013, In : Journal of Medicinal Food. 16, 12, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Impact of caffeic acid on aluminium chloride-induced dementia in rats

Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In : Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In : Lipids. 48, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2012

Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice

Bansal, P., Paul, P., Mudgal, J., G. Nayak, P., Thomas Pannakal, S., Priyadarsini, K. I. & Unnikrishnan, M. K., 2012, In : Experimental and Toxicologic Pathology. 64, 6, p. 651-658 8 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

NO-NSAIDs. Part 3: Nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs

Borhade, N., Pathan, A. R., Halder, S., Karwa, M., Dhiman, M., Pamidiboina, V., Gund, M., Deshattiwar, J. J., Mali, S. V., Deshmukh, N. J., Senthilkumar, S. P., Gaikwad, P., Tipparam, S. G., Mudgal, J., Dutta, M. C., Burhan, A. U., Thakre, G., Sharma, A., Deshpande, S., Desai, D. C. & 5 others, Dubash, N. P., Jain, A. K., Sharma, S., Nemmani, K. V. S. & Satyam, A., 01-04-2012, In : Chemical and Pharmaceutical Bulletin. 60, 4, p. 465-481 17 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

Ameliorative effect of caffeic acid against inflammatory pain in rodents

Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In : European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In : Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In : Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)