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Research Output 2011 2019

  • 410 Citations
  • 11 h-Index
  • 40 Article
  • 1 Review article
2019
2 Citations (Scopus)

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Illness Behavior
Cannabinoid Receptors
Lipopolysaccharides
Oxidative Stress
Tumor Necrosis Factor-alpha
1 Citation (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reperfusion
Ischemia
Celecoxib
Kidney

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

Illness Behavior
Coffee
anxiety
caffeic acid
caffeine
1 Citation (Scopus)
Chitosan
Oligosaccharides
Nanoparticles
Cyclophosphamide
Chitin

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

Silymarin
Liposomes
Wistar Rats
Alcohols
Biological Availability
2 Citations (Scopus)

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In : European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.

Research output: Contribution to journalArticle

Indoles
Quinoxalines
Zebrafish
Multiple Sclerosis
Arthritis

Neprilysin, the kidney brush border neutral proteinase: a possible potential target for ischemic renal injury

Sankhe, R., Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2019, (Accepted/In press) In : Toxicology Mechanisms and Methods.

Research output: Contribution to journalReview article

Neprilysin
Kidney
Wounds and Injuries
Natriuretic Peptides
Ischemia
Memory Disorders
Aluminum
Rats
Acetylcholinesterase
Data storage equipment
2 Citations (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

Metformin
Lipopolysaccharides
Down-Regulation
Illness Behavior
Oxidative Stress
2018
1 Citation (Scopus)

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 03-10-2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticle

Macrophages
Antioxidants
Inflammation
Heme Oxygenase (Decyclizing)
Molecules
Sodium Glutamate
Nutrition
Medical problems
Type 2 Diabetes Mellitus
Blood Vessels
1 Citation (Scopus)

Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In : European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

Research output: Contribution to journalArticle

Interleukin-6
Lipopolysaccharides
Prostaglandin-Endoperoxide Synthases
Reactive Oxygen Species
Tarsal Joints
1 Citation (Scopus)

Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 07-03-2018, (Accepted/In press) In : Metabolic Brain Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

Purinergic P1 Receptor Antagonists
Cyclooxygenase Inhibitors
Haloperidol
Antipsychotic Agents
Caffeine
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan
2017
3 Citations (Scopus)

An insight into the role of cyclooxygenase and lipooxygenase pathway in renal ischemia

Kinra, M., Mudgal, J., Arora, D. & Nampoothiri, M., 01-01-2017, In : European Review for Medical and Pharmacological Sciences. 21, 21, p. 5017-5020 4 p.

Research output: Contribution to journalArticle

Prostaglandin-Endoperoxide Synthases
Ischemia
Kidney
Oxidative Stress
Inflammation Mediators
2016
Aluminum
Curcumin
Aptitude
Water
Neurodegenerative Diseases
Niacin
Memory Disorders
Dementia
Aluminum
Water
18 Citations (Scopus)

Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

Basu Mallik, S., Mudgal, J., Nampoothiri, M., Hall, S., Dukie, S. A., Grant, G., Rao, C. M. & Arora, D., 06-10-2016, In : Neuroscience Letters. 632, p. 218-223 6 p.

Research output: Contribution to journalArticle

Illness Behavior
Lipopolysaccharides
Brain
Oxidative Stress
Antioxidants
1 Citation (Scopus)

Dose-related antihyperglycemic and hypolipidemic effects of two novel thiazolidin-4-ones in a rodent model of metabolic syndrome

Karot, S. S., Surenahalli, V. G., Kishore, A., Mudgal, J., Nandakumar, K., Chirayil, M. T., Mathew, G. & Nampurath, G. K., 01-09-2016, In : Journal of Diabetes. 8, 5, p. 629-639 11 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Rodentia
Interleukin-6
Reactive Oxygen Species
Nitric Oxide
Phenylephrine
Muscarinic Receptors
Thoracic Aorta
Vasodilator Agents
Vasodilation
9 Citations (Scopus)
Alpinia
Zingiberaceae
Rhizome
Inflammation
Peroxidase

In vitro and in vivo hepatoprotective action of L-α-phosphatidylcholine in alcohol-induced toxicity model

Raj, P. V., Mudgal, J., Reddy, N. D., Rao, C. M., Bansal, P., Rai, A. & Kumar, N., 01-11-2016, In : International Journal of Pharmaceutical Sciences Review and Research. 41, 1, p. 171-176 6 p., 33.

Research output: Contribution to journalArticle

Phosphatidylcholines
Silymarin
Alcohols
Sulfhydryl Compounds
Wistar Rats
2 Citations (Scopus)

In vitro cytotoxicity activity of chrysin, morin and resveratrol against MCF-7 breast cancer cell lines

Thomas, A., Ranadive, N., Nayak, H., Surendran, S., Nampoothiri, M., Mudgal, J. & Nayak, Y., 01-09-2016, In : Biosciences Biotechnology Research Asia. 13, 3, p. 1633-1637 5 p.

Research output: Contribution to journalArticle

resveratrol
breast neoplasms
cytotoxicity
cell lines
Breast Neoplasms
2 Citations (Scopus)

In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In : Frontiers in Pharmacology. 7, OCT, 381.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Sucrose
Diet
Phosphorylation
2 Citations (Scopus)
Arthritis
Experimental Arthritis
Cytokines
Dinoprostone
Stomach
2015
2 Citations (Scopus)

Anti-tubercular activity of synthesized novel 2,5-disubstituted-1,3,4-oxadiazole derivatives

Ega, D., Attari, Z., Mudgal, J., Bairy, I., Vishnuprasad, S. & Nampurath, G. K., 2015, In : Indian Drugs. 52, 2, p. 40-44 5 p.

Research output: Contribution to journalArticle

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Durgashivaprasad, E., Attari, Z., Mudgal, J., Bairy, L. K., Vishnu Prasad, S. & Kutty Nampurath, G., 2015, In : Indian Drugs. 52, 2, p. 40-44. 5 p.

Research output: Contribution to journalArticle

Isoniazid
1,3,4-oxadiazole
31 Citations (Scopus)
Simvastatin
Frontal Lobe
Aluminum
Hippocampus
Rivastigmine
23 Citations (Scopus)

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

Research output: Contribution to journalArticle

Lipids
Frontal Lobe
Hippocampus
Sesame Oil
Rivastigmine
2014
13 Citations (Scopus)

Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

Durgashivaprasad, E., Mathew, G., Sebastian, S., Manohar Reddy, S. A., Mudgal, J. & Nampurath, G. K., 2014, In : Indian Journal of Pharmacology. 46, 5, p. 521-526 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In : Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Carrageenan
Cytokines
Inflammation
Dinoprostone
Rats
3 Citations (Scopus)
Clofibric Acid
Acetic Acid
Insulin Resistance
Insulin
Medical problems
2013
3 Citations (Scopus)

Evaluation of in vitro antioxidant and in Vivo analgesic potential of Terminalia paniculata aqueous bark extract

Talwar, S., Nayak, P. G., Mudgal, J., Paul, P., Bansal, P. & Nandakumar, K., 2013, In : Journal of Medicinal Food. 16, 12, p. 1153-1161 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Impact of caffeic acid on aluminium chloride-induced dementia in rats

Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In : Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

Research output: Contribution to journalArticle

Dementia
Brain
Acetylcholinesterase
Nitrites
Glutathione Transferase
21 Citations (Scopus)

Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In : Lipids. 48, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Triglycerides
Cholesterol
Plasmas
Nutrition
2012
93 Citations (Scopus)

Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice

Bansal, P., Paul, P., Mudgal, J., G. Nayak, P., Thomas Pannakal, S., Priyadarsini, K. I. & Unnikrishnan, M. K., 2012, In : Experimental and Toxicologic Pathology. 64, 6, p. 651-658 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

NO-NSAIDs. Part 3: Nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs

Borhade, N., Pathan, A. R., Halder, S., Karwa, M., Dhiman, M., Pamidiboina, V., Gund, M., Deshattiwar, J. J., Mali, S. V., Deshmukh, N. J., Senthilkumar, S. P., Gaikwad, P., Tipparam, S. G., Mudgal, J., Dutta, M. C., Burhan, A. U., Thakre, G., Sharma, A., Deshpande, S., Desai, D. C. & 5 others, Dubash, N. P., Jain, A. K., Sharma, S., Nemmani, K. V. S. & Satyam, A., 01-04-2012, In : Chemical and Pharmaceutical Bulletin. 60, 4, p. 465-481 17 p.

Research output: Contribution to journalArticle

Prodrugs
Non-Steroidal Anti-Inflammatory Agents
Nitric Oxide
Anti-Inflammatory Agents
Imides
2011
45 Citations (Scopus)

Ameliorative effect of caffeic acid against inflammatory pain in rodents

Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In : European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

Research output: Contribution to journalArticle

Rodentia
Pain
Analgesics
Nitrites
nimesulide
32 Citations (Scopus)

Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In : Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

Research output: Contribution to journalArticle

Terminalia
Anti-Inflammatory Agents
Freund's Adjuvant
Carrageenan
Inflammation
18 Citations (Scopus)

Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In : Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

Research output: Contribution to journalArticle

Quinoxalines
Anti-Inflammatory Agents
Antioxidants
Derivatives
Ricinoleic Acids