Jessy E Mathew

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Phone+91-9611534075
Emailjessy.james@manipal.edu
Websitehttps://manipal.edu/mcops-manipal/department-faculty/faculty-list/jessy-elizabeth-mathew.html

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Medicinal Chemistry

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182 Citations
8 h-Index
26 Article

CuCl₂-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors
Thirupataiah, B., Mounika, G., Sujeevan Reddy, G., Sandeep Kumar, J., Kapavarapu, R., Medishetti, R., Mudgal, J., Mathew, J. E., Shenoy, G. G., Mallikarjuna Rao, C., Chatti, K., V. L. Parsa, K. & Pal, M., 10-2021, In: Bioorganic Chemistry. 115, 105265.
Research output: Contribution to journal › Article › peer-review
PdCl₂-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor
Thirupataiah, B., Mounika, G., Reddy, G. S., Kumar, J. S., Hossain, K. A., Medishetti, R., Samarpita, S., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Rao, C. M., Chatti, K., Parsa, K. V. L. & Pal, M., 05-10-2021, In: European Journal of Medicinal Chemistry. 221, 113514.
Research output: Contribution to journal › Article › peer-review
Isolation and characterization of phytoconstituents from stem of elytranthe parasitica(L.) danser
Kumar, N., Lobo, R. & Mathew, J. E., 01-10-2020, In: Rasayan Journal of Chemistry. 13, 4, p. 2281-2289 9 p.
Research output: Contribution to journal › Article › peer-review
Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl₃-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor
Thirupataiah, B., Reddy, G. S., Ghule, S. S., Kumar, J. S., Mounika, G., Hossain, K. A., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 04-2020, In: Bioorganic Chemistry. 97, 103691.
Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)
InCl ₃ mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis
Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E. V. V. S., Kumar, J. S., Doss, H. M., Medishetti, R., Kulkarni, P., Kapavarapu, R. K., Rasool, M., Mudgal, J., Mathew, J. E., Shenoy, G. G., Parsa, K. V. L. & Pal, M., 15-07-2019, In: European Journal of Medicinal Chemistry. 174, p. 198-215 18 p.
Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus)

Jessy E Mathew

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CuCl₂-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors

PdCl₂-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor

Isolation and characterization of phytoconstituents from stem of elytranthe parasitica(L.) danser

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl₃-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

InCl ₃ mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

Jessy E Mathew

Personal profile

Research Interests

External positions

Fingerprint

Network

Research output

CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors

PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor

Isolation and characterization of phytoconstituents from stem of elytranthe parasitica(L.) danser

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

InCl 3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis

CuCl₂-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors

PdCl₂-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor

Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl₃-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

InCl ₃ mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis