If you made any changes in Pure these will be visible here soon.

Research Output 1999 2019

  • 707 Citations
  • 17 h-Index
  • 72 Article
  • 1 Chapter
  • 1 Review article
2019
Caesalpinia
Hep G2 Cells
Acetaminophen
Glutathione
Genes
1 Citation (Scopus)

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Illness Behavior
Cannabinoid Receptors
Lipopolysaccharides
Oxidative Stress
Tumor Necrosis Factor-alpha

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reperfusion
Ischemia
Celecoxib
Kidney
Memory Disorders
Aluminum
Rats
Acetylcholinesterase
Data storage equipment
1 Citation (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

Tissue
Organ Size
Tissue Distribution
Individuality
Rodentia

Targeting HIV-TB coinfection by developing novel piperidin-4-substituted imines: Design, synthesis, in vitro and in silico studies

Kumar, A., Revathi, R., Sriram, D., Curreli, F., Debnath, A. K., Pai, K. S. & Kini, S. G., 01-06-2019, In : Archiv der Pharmazie. 352, 6, 1800358.

Research output: Contribution to journalArticle

Imines
Coinfection
Computer Simulation
HIV
Anti-HIV Agents
2018

Amelioration of arsenic-induced oxidative stress in CHO cells by Ixora coccinea flower extract

Salmataj, S. A., Kamath, S. U., Murty, V. R. & Pai, S. R., 01-10-2018, In : 3 Biotech. 8, 10, 446.

Research output: Contribution to journalArticle

Ixora coccinea
CHO Cells
Arsenic
arsenic
flower

Antimicrobial activity of aqueous and ethanolic leaf extracts of anacardium occidentale

Shobha, K. L., Rao, A. S., Pai, K. S. R. & Bhat, S., 01-12-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 12, p. 474-476 3 p.

Research output: Contribution to journalArticle

Anacardium
Klebsiella pneumoniae
Escherichia coli
Enterococcus faecalis
Plant Extracts
Thyroidectomy
Thyroxine
Pharmacokinetics
Radio
Thyroid Neoplasms
arsenate
Rutin
flower
Antioxidants
Traditional Medicine

Modulatory role of mucuna pruriens against aluminium fluoride induced neuronal and behavioural alterations in rats

Nayak, V. S., Kumar, N., Dsouza, A. S., Nayak, S. S. & Pai, K. S. R., 01-04-2018, In : Journal of Clinical and Diagnostic Research. 12, 4, p. FC01-FC04

Research output: Contribution to journalArticle

Mucuna
Oxidative stress
Rats
Oxidative Stress
Quercetin
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan

Prediction of Tumor-to-Plasma Ratios of Basic Compounds in Subcutaneous Xenograft Mouse Models

Nigade, P. B., Gundu, J., Pai, K. S. & Nemmani, K. V. S., 01-06-2018, In : European Journal of Drug Metabolism and Pharmacokinetics. p. 1-16 16 p.

Research output: Contribution to journalArticle

Heterografts
Neoplasms
Oral Administration
Spleen

Structural Elucidation of Alkaloids from Aerial Parts of Rivea hypocrateriformis and Their Antihemolytic and Cytotoxic Activity

Godipurge, S. S., Biradar, J. S., Biradar, N. J., Shivarudrappa, H. P., Yallappa, S., Hungund, B. S. & Sreedhara Ranganath Pai, K., 01-01-2018, In : Chemistry of Natural Compounds. 54, 1, p. 142-146 5 p.

Research output: Contribution to journalArticle

aerial parts
alkaloids
breast neoplasms
spectral analysis
cytotoxicity
2017

Anticancer activity of stem bark extract and fractions of Wrightia tinctoria in transplantable tumors in mice

Chaudhary, S., Setty, M. M. & Pai, K. S. R., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1995-2000 6 p.

Research output: Contribution to journalArticle

Ascites
tumor
bark
Mouse
Tumors
1 Citation (Scopus)
Oxadiazoles
MCF-7 Cells
Cytotoxicity
Caspase 2
Acridine Orange
2 Citations (Scopus)

Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice

Nigade, P. B., Gundu, J., Sreedhara Pai, K. & Nemmani, K. V. S., 01-10-2017, In : European Journal of Drug Metabolism and Pharmacokinetics. 42, 5, p. 835-847 13 p.

Research output: Contribution to journalArticle

Muscles
Organ Size
Skin
Brain
Pharmaceutical Preparations
2 Citations (Scopus)

Promising anticancer activities of Justicia simplex D. Don. in cellular and animal models

Joseph, L., Aranjani, J. M., Pai, K. S. R. & Srinivasan, K. K., 06-03-2017, In : Journal of Ethnopharmacology. 199, p. 231-239 9 p.

Research output: Contribution to journalArticle

Justicia
Animal Models
Vascular Endothelial Growth Factor A
Neoplasms
Growth

Review of pharmacokinetics of levothyroxine, with specific focus on patient with thyroid carcinoma

Kumar, R., Prabhu, M., Pai, S. R. & Shenoy, V., 01-01-2017, In : Journal of Global Pharma Technology. 9, 10

Research output: Contribution to journalReview article

Thyroxine
Thyroid Neoplasms
Pharmacokinetics
Thyroidectomy
Radio

Rose apple (syzygium jambos (L.) alston)

Baliga, M. S., Pai, K. S. R., Saldanha, E., Ratnu, V. S., Priya, R., Adnan, M. & Naik, T. S., 21-09-2017, Fruit and Vegetable Phytochemicals: Chemistry and Human Health: Second Edition. Wiley-Blackwell, Vol. 2. p. 1235-1241 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Screening of anticancer activity of selected medicinal plants indigenous to Western Ghats: Argyreia nervosa, Memecylon malabaricum and Memecylon umbellatum

Chaudhary, S., Chandrashekar, K. S., Pai, K. S. R., Setty, M. M., Devkar, R. A., Reddy, N. D. & Biswas, S., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1781-1784 4 p.

Research output: Contribution to journalArticle

medicinal plant
Medicinal Plants
Screening
cancer
Cells
3 Citations (Scopus)

Sodium valproate enhances doxorubicin-induced cognitive dysfunction in Wistar rats

Verma, T., Mallik, S. B., Ramalingayya, G. V., Nayak, P. G., Kishore, A., Pai, K. S. R. & Nandakumar, K., 01-12-2017, In : Biomedicine and Pharmacotherapy. 96, p. 736-741 6 p.

Research output: Contribution to journalArticle

Valproic Acid
Histone Deacetylases
Doxorubicin
Wistar Rats
Antioxidants
2 Citations (Scopus)

The effects of Mucuna pruriens extract on histopathological and biochemical features in the rat model of ischemia

Nayak, V. S., Kumar, N., D'Souza, A. S., Nayak, S. S., Cheruku, S. P. & Pai, K. S. R., 01-01-2017, In : NeuroReport. 28, 18, p. 1195-1201 7 p.

Research output: Contribution to journalArticle

Mucuna
Ischemia
Brain Ischemia
Brain
Carotid Arteries
2016
2 Citations (Scopus)

1,2,3-Triazolyl pyrazole derivatives as anti-cancer agents: Biological evaluation and molecular docking

Bhat, M., Nagaraja, G. K., Kayarmar, R., Sreedhara Ranganath Pai, K., Biswas, S. & Mohammed Shafeeullah, R., 2016, In : Der Pharma Chemica. 8, 19, p. 200-221 22 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Estrogen Receptors
Toremifene
Cells
Derivatives
5 Citations (Scopus)

Assessment of the in vitro cytotoxicity and in vivo anti-tumor activity of the alcoholic stem bark extract/fractions of Mimusops elengi Linn.

Kumar, H., Savaliya, M., Biswas, S., Nayak, P. G., Maliyakkal, N., Manjunath Setty, M., Gourishetti, K. & Pai, K. S. R., 01-08-2016, In : Cytotechnology. 68, 4, p. 861-877 17 p.

Research output: Contribution to journalArticle

Mimusops
Cytotoxicity
Tumors
Assays
Micronucleus Tests
2 Citations (Scopus)

Bulbophyllum sterile petroleum ether fraction induces apoptosis in vitro and ameliorates tumor progression in vivo

Biswas, S., Pardeshi, R., Reddy, N. D., Shoja, M. H., Nayak, P. G., Setty, M. M. & Pai, K. S. R., 01-12-2016, In : Biomedicine and Pharmacotherapy. 84, p. 1419-1427 9 p.

Research output: Contribution to journalArticle

Petroleum
Apoptosis
Cell Cycle
HCT116 Cells
Neoplasms
1 Citation (Scopus)

Design, synthesis, characterization of some new 1,2,3-triazolyl chalcone derivatives as potential anti-microbial, anti-oxidant and anti-cancer agents via a Claisen-Schmidt reaction approach

Bhat, M., Nagaraja, G. K., Divyaraj, P., Harikrishna, N., Sreedhara Ranganath Pai, K., Biswas, S. & Peethamber, S. K., 2016, In : RSC Advances. 6, 102, p. 99794-99808 15 p.

Research output: Contribution to journalArticle

Chalcone
Oxidants
Derivatives
Nuclear magnetic resonance
Sodium Hydroxide
2 Citations (Scopus)
Ceiba
Cytotoxicity
Ascites
Tumors
Cells
5 Citations (Scopus)
Caesalpinia
Liver Cirrhosis
Liver
Silymarin
Control Groups
Geriatrics
Tertiary Healthcare
Teaching Hospitals
Teaching
Prospective Studies
3 Citations (Scopus)

Novel Indole-Quinazolinone Based Amides as Cytotoxic Agents

Gokhale, N., Panathur, N., Dalimba, U., Nayak, P. G. & Pai, K. S. R., 01-03-2016, In : Journal of Heterocyclic Chemistry. 53, 2, p. 513-524 12 p.

Research output: Contribution to journalArticle

lissamine rhodamine B
Quinazolinones
Cytotoxins
Cytotoxicity
Amides
13 Citations (Scopus)
Halogens
MCF-7 Cells
Cells
Assays
Bromine
1 Citation (Scopus)

Synthesis, spectroscopic and anti tumor studies on copper(II) complex of orthohydroxypropiophenoneisonicotinoylhydrazone

Ramesh, G. N., Prathima, B., Rao, Y. S., Reddy, Y. P., Pai, K. S. R. & Reddy, A. V., 01-09-2016, In : Arabian Journal of Chemistry. 9, p. S404-S410

Research output: Contribution to journalArticle

Tumors
Copper
Ligands
X ray powder diffraction
Paramagnetic resonance
2 Citations (Scopus)
Tertiary Care Centers
Urinary Tract Infections
India
Pharmaceutical Services
Prospective Studies
2015
4 Citations (Scopus)
1 Citation (Scopus)
8 Citations (Scopus)

Design, synthesis, antioxidant and anticancer activity of novel pyrazole derivatives

Mubeen, M., Kini, S. G. & Pai, K. S. R., 2015, In : Der Pharma Chemica. 7, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effects of withania somnifera and tinospora cordifolia extracts on the side population phenotype of human epithelial cancer cells: Toward targeting multidrug resistance in cancer

Maliyakkal, N., Appadath Beeran, A., Balaji, S. A., Udupa, N., Ranganath Pai, S. & Rangarajan, A., 17-03-2015, In : Integrative Cancer Therapies. 14, 2, p. 156-171 16 p.

Research output: Contribution to journalArticle

Tinospora
Withania
Multiple Drug Resistance
Epithelial Cells
Phenotype
26 Citations (Scopus)

Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma

Chaudhary, S., Chandrashekar, K. S. U., Pai, K. S. R. R., Setty, M., Devkar, R. A. N., Reddy, N. D. N. & Shoja, M. H. A., 01-01-2015, In : BMC Complementary and Alternative Medicine. 15, 1 p.

Research output: Contribution to journalArticle

Nardostachys
Methanol
Antioxidants
Breast Neoplasms
Ether
17 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

Sulfonamides
Caspase 7
Colon
Adenocarcinoma
Annexin A5
1 Citation (Scopus)
28 Citations (Scopus)

Some new indole-coumarin hybrids; Synthesis, anticancer and Bcl-2 docking studies

Kamath, P. R., Sunil, D., Ajees, A. A., Pai, K. S. R. & Das, S., 2015, In : Bioorganic Chemistry. 63, p. 101-109 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents

Sankappa Rai, U., Isloor, A. M., Shetty, P., Pai, K. S. R. & Fun, H. K., 2015, In : Arabian Journal of Chemistry. 8, 3, p. 317-321 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Synthesis and pharmacological evaluation of some new fluorine containing hydroxypyrazolines as potential anticancer and antioxidant agents

[Unknown], D., Viveka, S., Priya, B. K., Pai, K. S. R., Naveen, S., Lokanath, N. K. & Nagaraja, G. K., 2015, In : European Journal of Medicinal Chemistry. 104, p. 25-32 8 p.

Research output: Contribution to journalArticle

2014
9 Citations (Scopus)
3 Citations (Scopus)

Hepatoprotective role of Caesalpenia bonduc: A histopathological and biochemical study

Sumalatha, S., Pai, K. S. R., Kumar, N. & Bhat, K. M. R., 20-11-2014, In : Journal of Clinical and Diagnostic Research. 8, 11, p. HF05-HF07

Research output: Contribution to journalArticle

Rats
Medicine
Animals
Blood
Carbon Tetrachloride
1 Citation (Scopus)

In vitro cytotoxic and apoptotic effect of Mimusops elengi Linn. methanolic bark extract

Kumar, H., Pai, K. S. R., Maliyakkal, N., Mihir, S. & Singh, C., 2014, In : Biomedicine and Preventive Nutrition. 4, 4, p. 579-588 10 p.

Research output: Contribution to journalArticle

2013
1 Citation (Scopus)
20 Citations (Scopus)
Tinospora
Withania
Breast Neoplasms
Complex Mixtures
Plant Extracts