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Research Output 1999 2019

  • 750 Citations
  • 18 h-Index
  • 76 Article
  • 1 Chapter
  • 1 Review article
32 Citations (Scopus)

Vasorelaxant and antihypertensive effect of Cocos nucifera Linn. endocarp on isolated rat thoracic aorta and DOCA salt-induced hypertensive rats

Bankar, G. R., Nayak, P. G., Bansal, P., Paul, P., Pai, K. S. R., Singla, R. K. & Bhat, V. G., 2011, In : Journal of Ethnopharmacology. 134, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Tertiary Care Centers
Urinary Tract Infections
India
Pharmaceutical Services
Prospective Studies
1 Citation (Scopus)

The Role of Natural Medicines on Wound Healing: A Biomechanical, Histological, Biochemical and Molecular Study

Kotian, S., Bhat, K., Pai, S., Nayak, J., Souza, A., Gourisheti, K. & Padma, D., 01-11-2018, In : Ethiopian journal of health sciences. 28, 6, p. 759-770 12 p.

Research output: Contribution to journalArticle

Wound Healing
Traditional Medicine
Myofibroblasts
Wounds and Injuries
Nerium
2 Citations (Scopus)

The effects of Mucuna pruriens extract on histopathological and biochemical features in the rat model of ischemia

Nayak, V. S., Kumar, N., D'Souza, A. S., Nayak, S. S., Cheruku, S. P. & Pai, K. S. R., 01-01-2017, In : NeuroReport. 28, 18, p. 1195-1201 7 p.

Research output: Contribution to journalArticle

Mucuna
Ischemia
Brain Ischemia
Brain
Carotid Arteries

Targeting HIV-TB coinfection by developing novel piperidin-4-substituted imines: Design, synthesis, in vitro and in silico studies

Kumar, A., Revathi, R., Sriram, D., Curreli, F., Debnath, A. K., Pai, K. S. & Kini, S. G., 01-06-2019, In : Archiv der Pharmazie. 352, 6, 1800358.

Research output: Contribution to journalArticle

Imines
Coinfection
Computer Simulation
HIV
Anti-HIV Agents
30 Citations (Scopus)

Synthesis and pharmacological screening of some novel naphtho [2,1-b] furo-pyrazolines, isoxazoles and isoxazolines

Vagdevi, H. M., Latha, K. P., Vaidya, V. P., Vijaya Kumar, M. L. & Pai, K. S. R., 01-12-2001, In : Indian Journal of Pharmaceutical Sciences. 63, 4, p. 286-291 6 p.

Research output: Contribution to journalArticle

Chalcones
Isoxazoles
Anthelmintics
hydrazine
Analgesics
22 Citations (Scopus)

Synthesis and pharmacological evaluation of some new fluorine containing hydroxypyrazolines as potential anticancer and antioxidant agents

[Unknown], D., Viveka, S., Priya, B. K., Pai, K. S. R., Naveen, S., Lokanath, N. K. & Nagaraja, G. K., 2015, In : European Journal of Medicinal Chemistry. 104, p. 25-32 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents

Sankappa Rai, U., Isloor, A. M., Shetty, P., Pai, K. S. R. & Fun, H. K., 2015, In : Arabian Journal of Chemistry. 8, 3, p. 317-321 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis and biological evaluation of benzofuran incorporated benzodiazepines

Harinadha Babu, V., Gupta, A., Srinivasan, K. K. & Pai, K. S. R., 2005, In : Indian Journal of Heterocyclic Chemistry. 14, 3, p. 267-268 2 p.

Research output: Contribution to journalArticle

Chalcones
Benzodiazepines
Hypnotics and Sedatives
Aldehydes
Condensation
66 Citations (Scopus)

Synthesis and antitumor studies on novel Co(II), Ni(II) and Cu(II) metal complexes of bis(3-acetylcoumarin)thiocarbohydrazone

Sathisha, M. P., Shetti, U. N., Revankar, V. K. & Pai, K. S. R., 2008, In : European Journal of Medicinal Chemistry. 43, 11, p. 2338-2346 9 p.

Research output: Contribution to journalArticle

Coordination Complexes
Ligands
Dimethyl Sulfoxide
Dimethylformamide
Lactones
21 Citations (Scopus)
Electrochemistry
Coordination Complexes
Ascites
Copper
Carcinoma
40 Citations (Scopus)
Isatin
Electrochemistry
Coordination Complexes
Ascites
Ligands
2 Citations (Scopus)

Synthesis, spectroscopic and anti tumor studies on copper(II) complex of orthohydroxypropiophenoneisonicotinoylhydrazone

Ramesh, G. N., Prathima, B., Rao, Y. S., Reddy, Y. P., Pai, K. S. R. & Reddy, A. V., 01-09-2016, In : Arabian Journal of Chemistry. 9, p. S404-S410

Research output: Contribution to journalArticle

Tumors
Copper
Ligands
X ray powder diffraction
Paramagnetic resonance
3 Citations (Scopus)

Synthesis, docking and anti-tumor activity of β-L-1,3-thiazolidine pyrimidine nucleoside analogues

Sriharsha, S. N., Ranganath Pai, K. S., [Unknown], S., Shashikanth, S., Chandra, N. & Prabhu, K. R., 2007, In : Medicinal Chemistry. 3, 5, p. 425-432 8 p.

Research output: Contribution to journalArticle

Thiazolidines
Pyrimidine Nucleosides
Nucleosides
Cysteine
Lewis Acids
87 Citations (Scopus)

Synthesis, characterization and biological activities of some new benzo[b]thiophene derivatives

Isloor, A. M., Kalluraya, B. & Sridhar Pai, K., 2010, In : European Journal of Medicinal Chemistry. 45, 2, p. 825-830 6 p.

Research output: Contribution to journalArticle

Bioactivity
Derivatives
Molecules
Pyrazoles
Thiadiazoles
23 Citations (Scopus)

Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells

Isloor, A. M., Sunil, D., Shetty, P., Malladi, S., Pai, K. S. R. & Maliyakkl, N., 2013, In : Medicinal Chemistry Research. 22, 2, p. 758-767 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synthesis, antitumor, and DNA binding behavior of novel 4-(2-Hydroxyquinolin-3-yl)-6-Phenyl-5, 6 dihydropyrimidin derivatives in aqueous medium

Lamani, D. S., Reddy, K. R. V., Naik, H. S. B., Pai, K. S. R., Kumar, R., Naik, H. R. P. & Naik, L. R., 2010, In : Nucleosides, Nucleotides and Nucleic Acids. 29, 8, p. 591-605 15 p.

Research output: Contribution to journalArticle

Chalcones
Derivatives
Thiourea
DNA
MCF-7 Cells

Structural Elucidation of Alkaloids from Aerial Parts of Rivea hypocrateriformis and Their Antihemolytic and Cytotoxic Activity

Godipurge, S. S., Biradar, J. S., Biradar, N. J., Shivarudrappa, H. P., Yallappa, S., Hungund, B. S. & Sreedhara Ranganath Pai, K., 01-01-2018, In : Chemistry of Natural Compounds. 54, 1, p. 142-146 5 p.

Research output: Contribution to journalArticle

aerial parts
alkaloids
breast neoplasms
spectral analysis
cytotoxicity
31 Citations (Scopus)

Some new indole-coumarin hybrids; Synthesis, anticancer and Bcl-2 docking studies

Kamath, P. R., Sunil, D., Ajees, A. A., Pai, K. S. R. & Das, S., 2015, In : Bioorganic Chemistry. 63, p. 101-109 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Sodium valproate enhances doxorubicin-induced cognitive dysfunction in Wistar rats

Verma, T., Mallik, S. B., Ramalingayya, G. V., Nayak, P. G., Kishore, A., Pai, K. S. R. & Nandakumar, K., 01-12-2017, In : Biomedicine and Pharmacotherapy. 96, p. 736-741 6 p.

Research output: Contribution to journalArticle

Valproic Acid
Histone Deacetylases
Doxorubicin
Wistar Rats
Antioxidants
20 Citations (Scopus)

Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts

Nayak, P. G., Paul, P., Bansal, P., Kutty, N. G. & Pai, K. S. R., 2013, In : Journal of Pharmacy and Pharmacology. 65, 7, p. 1083-1093 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Screening of anticancer activity of selected medicinal plants indigenous to Western Ghats: Argyreia nervosa, Memecylon malabaricum and Memecylon umbellatum

Chaudhary, S., Chandrashekar, K. S., Pai, K. S. R., Setty, M. M., Devkar, R. A., Reddy, N. D. & Biswas, S., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1781-1784 4 p.

Research output: Contribution to journalArticle

medicinal plant
Medicinal Plants
Screening
cancer
Cells

Rose apple (syzygium jambos (L.) alston)

Baliga, M. S., Pai, K. S. R., Saldanha, E., Ratnu, V. S., Priya, R., Adnan, M. & Naik, T. S., 21-09-2017, Fruit and Vegetable Phytochemicals: Chemistry and Human Health: Second Edition. Wiley-Blackwell, Vol. 2. p. 1235-1241 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Review of pharmacokinetics of levothyroxine, with specific focus on patient with thyroid carcinoma

Kumar, R., Prabhu, M., Pai, S. R. & Shenoy, V., 01-01-2017, In : Journal of Global Pharma Technology. 9, 10

Research output: Contribution to journalReview article

Thyroxine
Thyroid Neoplasms
Pharmacokinetics
Thyroidectomy
Radio
3 Citations (Scopus)

Promising anticancer activities of Justicia simplex D. Don. in cellular and animal models

Joseph, L., Aranjani, J. M., Pai, K. S. R. & Srinivasan, K. K., 06-03-2017, In : Journal of Ethnopharmacology. 199, p. 231-239 9 p.

Research output: Contribution to journalArticle

Justicia
Animal Models
Vascular Endothelial Growth Factor A
Neoplasms
Growth
1 Citation (Scopus)

Preventive role of Emblica offcinalis and Cissus quadrangularis on bone loss in osteoporosis

Rao Sirasanagandla, S., Sreedhara Ranganath Pai, K. & Bhat, K. M., 16-10-2013, In : International Journal of Pharmacy and Pharmaceutical Sciences. 5, 4, p. 465-470 6 p.

Research output: Contribution to journalArticle

Cissus
Phyllanthus emblica
Osteoporosis
Bone and Bones
Hydroxyproline
5 Citations (Scopus)

Preventive role of Emblica offcinalis and Cissus quadrangularis on bone loss in osteoporosis

Sirasanagandla, S. R., Sreedhara Ranganath Pai, K. & Bhat, K. M. R., 02-12-2013, In : International Journal of Pharmacy and Pharmaceutical Sciences. 5, SUPPL.4, p. 122-127 6 p.

Research output: Contribution to journalArticle

Cissus
Phyllanthus emblica
Osteoporosis
Bone and Bones
Hydroxyproline
36 Citations (Scopus)
Cytotoxicity
Ascites
Tumors
Assays
Lymphoma
1 Citation (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

Tissue
Organ Size
Tissue Distribution
Individuality
Rodentia

Prediction of Tumor-to-Plasma Ratios of Basic Compounds in Subcutaneous Xenograft Mouse Models

Nigade, P. B., Gundu, J., Pai, K. S. & Nemmani, K. V. S., 01-06-2018, In : European Journal of Drug Metabolism and Pharmacokinetics. p. 1-16 16 p.

Research output: Contribution to journalArticle

Heterografts
Neoplasms
Oral Administration
Spleen
2 Citations (Scopus)

Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice

Nigade, P. B., Gundu, J., Sreedhara Pai, K. & Nemmani, K. V. S., 01-10-2017, In : European Journal of Drug Metabolism and Pharmacokinetics. 42, 5, p. 835-847 13 p.

Research output: Contribution to journalArticle

Muscles
Organ Size
Skin
Brain
Pharmaceutical Preparations

Pharmacophore modeling of delta and MU receptors and synthesis of enkephalines with D-[Leu] 5 C-terminal modification as delta selective agonists

Bhat, P., Mor, V., Muttineni, R., Pai, K. S. R., Chowdary, P. V. R. & Kota, S., 2012, In : International Journal of Pharmacy and Technology. 4, 2, p. 4350-4391 42 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
Halogens
MCF-7 Cells
Cells
Assays
Bromine
3 Citations (Scopus)

Novel Indole-Quinazolinone Based Amides as Cytotoxic Agents

Gokhale, N., Panathur, N., Dalimba, U., Nayak, P. G. & Pai, K. S. R., 01-03-2016, In : Journal of Heterocyclic Chemistry. 53, 2, p. 513-524 12 p.

Research output: Contribution to journalArticle

lissamine rhodamine B
Quinazolinones
Cytotoxins
Cytotoxicity
Amides
Memory Disorders
Aluminum
Rats
Acetylcholinesterase
Data storage equipment
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan
Geriatrics
Tertiary Healthcare
Teaching Hospitals
Teaching
Prospective Studies
1 Citation (Scopus)

Modulatory role of mucuna pruriens against aluminium fluoride induced neuronal and behavioural alterations in rats

Nayak, V. S., Kumar, N., Dsouza, A. S., Nayak, S. S. & Pai, K. S. R., 01-04-2018, In : Journal of Clinical and Diagnostic Research. 12, 4, p. FC01-FC04

Research output: Contribution to journalArticle

Mucuna
Oxidative stress
Rats
Oxidative Stress
Quercetin
22 Citations (Scopus)

In vivo anticancer and histopathology studies of Schiff bases on Ehrlich ascitic carcinoma cells. 1st Cancer Update.

Sunil, D., Isloor, A. M., Shetty, P., Nayak, P. G. & Pai, K. S. R., 2013, In : Arabian Journal of Chemistry. 6, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

In vitro cytotoxic and apoptotic effect of Mimusops elengi Linn. methanolic bark extract

Kumar, H., Pai, K. S. R., Maliyakkal, N., Mihir, S. & Singh, C., 2014, In : Biomedicine and Preventive Nutrition. 4, 4, p. 579-588 10 p.

Research output: Contribution to journalArticle

Acacia
Ethanol
Klebsiella pneumoniae
Escherichia coli
Candida
18 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

Sulfonamides
Caspase 7
Colon
Adenocarcinoma
Annexin A5

Influence of traditional medicines on the activity of keratinocytes in wound healing: An in-vitro study

Kotian, S. R., Bhat, K. M. R., Padma, D. & Pai, K. S. R., 01-01-2019, In : Anatomy and Cell Biology. 52, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

Traditional Medicine
Keratinocytes
Wound Healing
Nerium
Glycyrrhiza
3 Citations (Scopus)

Hepatoprotective role of Caesalpenia bonduc: A histopathological and biochemical study

Sumalatha, S., Pai, K. S. R., Kumar, N. & Bhat, K. M. R., 20-11-2014, In : Journal of Clinical and Diagnostic Research. 8, 11, p. HF05-HF07

Research output: Contribution to journalArticle

Rats
Medicine
Animals
Blood
Carbon Tetrachloride
5 Citations (Scopus)
Caesalpinia
Liver Cirrhosis
Liver
Silymarin
Control Groups
7 Citations (Scopus)

Growth promoting potential of Ficus bengalensis root extracts in immature female rats

Nidhiya, I. S. R., Pai, K. S. R. & Rao, C. M., 04-2009, In : Pharmaceutical Biology. 47, 4, p. 268-273 6 p.

Research output: Contribution to journalArticle

Ficus
Alcohols
Growth
Moraceae
Growth Plate
1 Citation (Scopus)

Free radical scavenging activity of extracts of young prop roots of ficus bengalensis

Nidhiya, I. S. R., Pai, K. S. R. & Mallikarjuna Rao, C., 2010, In : Pharmacologyonline. 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

Ficus
Free Radicals
Iron
Antioxidants
Moraceae
1 Citation (Scopus)
arsenate
Rutin
flower
Antioxidants
Traditional Medicine