If you made any changes in Pure these will be visible here soon.

Research Output 1999 2019

  • 741 Citations
  • 18 h-Index
  • 76 Article
  • 1 Chapter
  • 1 Review article
Article
3 Citations (Scopus)

1,2,3-Triazolyl pyrazole derivatives as anti-cancer agents: Biological evaluation and molecular docking

Bhat, M., Nagaraja, G. K., Kayarmar, R., Sreedhara Ranganath Pai, K., Biswas, S. & Mohammed Shafeeullah, R., 2016, In : Der Pharma Chemica. 8, 19, p. 200-221 22 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Estrogen Receptors
Toremifene
Cells
Derivatives

Amelioration of arsenic-induced oxidative stress in CHO cells by Ixora coccinea flower extract

Salmataj, S. A., Kamath, S. U., Murty, V. R. & Pai, S. R., 01-10-2018, In : 3 Biotech. 8, 10, 446.

Research output: Contribution to journalArticle

Ixora coccinea
CHO Cells
Arsenic
arsenic
flower
4 Citations (Scopus)

Angiotensin converting enzyme inhibitors from ripened and unripened bananas

Rao, N. M., Prasad, K. V. S. R. G. & Pai, K. S. R., 10-01-1999, In : Current Science. 76, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

peptidyl-dipeptidase A
bananas
cultivars
dialysis
hips
7 Citations (Scopus)

Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In : Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

Research output: Contribution to journalArticle

Berberis
Ascites
Cisplatin
Carcinoma
Artemia

Anticancer activity of stem bark extract and fractions of Wrightia tinctoria in transplantable tumors in mice

Chaudhary, S., Setty, M. M. & Pai, K. S. R., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1995-2000 6 p.

Research output: Contribution to journalArticle

Ascites
tumor
bark
Mouse
Tumors

Antimicrobial activity of aqueous and ethanolic leaf extracts of anacardium occidentale

Shobha, K. L., Rao, A. S., Pai, K. S. R. & Bhat, S., 01-12-2018, In : Asian Journal of Pharmaceutical and Clinical Research. 11, 12, p. 474-476 3 p.

Research output: Contribution to journalArticle

Anacardium
Klebsiella pneumoniae
Escherichia coli
Enterococcus faecalis
Plant Extracts
25 Citations (Scopus)

Antitumor and antioxidant activity of Polyalthia longifolia stem bark ethanol extract

Manjula, S. N., Kenganora, M., Parihar, V. K., Kumar, S., Nayak, P. G., Kumar, N., Ranganath Pai, K. S. & Rao, C. M., 2010, In : Pharmaceutical Biology. 48, 6, p. 690-696 7 p.

Research output: Contribution to journalArticle

Polyalthia
Ascites
Ethanol
Antioxidants
Inhibitory Concentration 50
5 Citations (Scopus)

Assessment of the in vitro cytotoxicity and in vivo anti-tumor activity of the alcoholic stem bark extract/fractions of Mimusops elengi Linn.

Kumar, H., Savaliya, M., Biswas, S., Nayak, P. G., Maliyakkal, N., Manjunath Setty, M., Gourishetti, K. & Pai, K. S. R., 01-08-2016, In : Cytotechnology. 68, 4, p. 861-877 17 p.

Research output: Contribution to journalArticle

Mimusops
Cytotoxicity
Tumors
Assays
Micronucleus Tests
9 Citations (Scopus)
6 Citations (Scopus)
1 Citation (Scopus)
Oxadiazoles
MCF-7 Cells
Cytotoxicity
Caspase 2
Acridine Orange
2 Citations (Scopus)

Bulbophyllum sterile petroleum ether fraction induces apoptosis in vitro and ameliorates tumor progression in vivo

Biswas, S., Pardeshi, R., Reddy, N. D., Shoja, M. H., Nayak, P. G., Setty, M. M. & Pai, K. S. R., 01-12-2016, In : Biomedicine and Pharmacotherapy. 84, p. 1419-1427 9 p.

Research output: Contribution to journalArticle

Petroleum
Apoptosis
Cell Cycle
HCT116 Cells
Neoplasms
Caesalpinia
Hep G2 Cells
Acetaminophen
Glutathione
Genes
2 Citations (Scopus)

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Illness Behavior
Cannabinoid Receptors
Lipopolysaccharides
Oxidative Stress
Tumor Necrosis Factor-alpha
40 Citations (Scopus)

Click Chemistry Approach for Bis-Chromenyl Triazole Hybrids and Their Antitubercular Activity

Naik, R. J., Kulkarni, M. V., Sreedhara Ranganath Pai, K. & Nayak, P. G., 2012, In : Chemical Biology and Drug Design. 80, 4, p. 516-523 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
20 Citations (Scopus)
Tinospora
Withania
Breast Neoplasms
Complex Mixtures
Plant Extracts
2 Citations (Scopus)
8 Citations (Scopus)

Design, synthesis, antioxidant and anticancer activity of novel pyrazole derivatives

Mubeen, M., Kini, S. G. & Pai, K. S. R., 2015, In : Der Pharma Chemica. 7, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

Computer Simulation
MCF-7 Cells
Allosteric Site
Inhibitory Concentration 50
Cell Line
1 Citation (Scopus)

Design, synthesis, characterization of some new 1,2,3-triazolyl chalcone derivatives as potential anti-microbial, anti-oxidant and anti-cancer agents via a Claisen-Schmidt reaction approach

Bhat, M., Nagaraja, G. K., Divyaraj, P., Harikrishna, N., Sreedhara Ranganath Pai, K., Biswas, S. & Peethamber, S. K., 2016, In : RSC Advances. 6, 102, p. 99794-99808 15 p.

Research output: Contribution to journalArticle

Chalcone
Oxidants
Derivatives
Nuclear magnetic resonance
Sodium Hydroxide
3 Citations (Scopus)

Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents

Deshpande, S. R., Pai, K. V. & Pai, R. S., 2011, In : Arzneimittel-Forschung/Drug Research. 61, 3, p. 180-185 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reperfusion
Ischemia
Celecoxib
Kidney
8 Citations (Scopus)

Effects of withania somnifera and tinospora cordifolia extracts on the side population phenotype of human epithelial cancer cells: Toward targeting multidrug resistance in cancer

Maliyakkal, N., Appadath Beeran, A., Balaji, S. A., Udupa, N., Ranganath Pai, S. & Rangarajan, A., 17-03-2015, In : Integrative Cancer Therapies. 14, 2, p. 156-171 16 p.

Research output: Contribution to journalArticle

Tinospora
Withania
Multiple Drug Resistance
Epithelial Cells
Phenotype
27 Citations (Scopus)

Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma

Chaudhary, S., Chandrashekar, K. S. U., Pai, K. S. R. R., Setty, M., Devkar, R. A. N., Reddy, N. D. N. & Shoja, M. H. A., 01-01-2015, In : BMC Complementary and Alternative Medicine. 15, 1 p.

Research output: Contribution to journalArticle

Nardostachys
Methanol
Antioxidants
Breast Neoplasms
Ether
3 Citations (Scopus)
Ceiba
Cytotoxicity
Ascites
Tumors
Cells
Thyroidectomy
Thyroxine
Pharmacokinetics
Radio
Thyroid Neoplasms
1 Citation (Scopus)
Carboxypeptidases
Fibrinolysin
Solanum tuberosum
Thrombosis
Fibrinolytic Agents
1 Citation (Scopus)
arsenate
Rutin
flower
Antioxidants
Traditional Medicine
1 Citation (Scopus)

Free radical scavenging activity of extracts of young prop roots of ficus bengalensis

Nidhiya, I. S. R., Pai, K. S. R. & Mallikarjuna Rao, C., 2010, In : Pharmacologyonline. 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

Ficus
Free Radicals
Iron
Antioxidants
Moraceae
7 Citations (Scopus)

Growth promoting potential of Ficus bengalensis root extracts in immature female rats

Nidhiya, I. S. R., Pai, K. S. R. & Rao, C. M., 04-2009, In : Pharmaceutical Biology. 47, 4, p. 268-273 6 p.

Research output: Contribution to journalArticle

Ficus
Alcohols
Growth
Moraceae
Growth Plate
5 Citations (Scopus)
Caesalpinia
Liver Cirrhosis
Liver
Silymarin
Control Groups
3 Citations (Scopus)

Hepatoprotective role of Caesalpenia bonduc: A histopathological and biochemical study

Sumalatha, S., Pai, K. S. R., Kumar, N. & Bhat, K. M. R., 20-11-2014, In : Journal of Clinical and Diagnostic Research. 8, 11, p. HF05-HF07

Research output: Contribution to journalArticle

Rats
Medicine
Animals
Blood
Carbon Tetrachloride

Influence of traditional medicines on the activity of keratinocytes in wound healing: An in-vitro study

Kotian, S. R., Bhat, K. M. R., Padma, D. & Pai, K. S. R., 01-01-2019, In : Anatomy and Cell Biology. 52, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

Traditional Medicine
Keratinocytes
Wound Healing
Nerium
Glycyrrhiza
18 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

Sulfonamides
Caspase 7
Colon
Adenocarcinoma
Annexin A5
Acacia
Ethanol
Klebsiella pneumoniae
Escherichia coli
Candida
1 Citation (Scopus)

In vitro cytotoxic and apoptotic effect of Mimusops elengi Linn. methanolic bark extract

Kumar, H., Pai, K. S. R., Maliyakkal, N., Mihir, S. & Singh, C., 2014, In : Biomedicine and Preventive Nutrition. 4, 4, p. 579-588 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

In vivo anticancer and histopathology studies of Schiff bases on Ehrlich ascitic carcinoma cells. 1st Cancer Update.

Sunil, D., Isloor, A. M., Shetty, P., Nayak, P. G. & Pai, K. S. R., 2013, In : Arabian Journal of Chemistry. 6, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Modulatory role of mucuna pruriens against aluminium fluoride induced neuronal and behavioural alterations in rats

Nayak, V. S., Kumar, N., Dsouza, A. S., Nayak, S. S. & Pai, K. S. R., 01-04-2018, In : Journal of Clinical and Diagnostic Research. 12, 4, p. FC01-FC04

Research output: Contribution to journalArticle

Mucuna
Oxidative stress
Rats
Oxidative Stress
Quercetin
1 Citation (Scopus)
Geriatrics
Tertiary Healthcare
Teaching Hospitals
Teaching
Prospective Studies
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan
Memory Disorders
Aluminum
Rats
Acetylcholinesterase
Data storage equipment
3 Citations (Scopus)

Novel Indole-Quinazolinone Based Amides as Cytotoxic Agents

Gokhale, N., Panathur, N., Dalimba, U., Nayak, P. G. & Pai, K. S. R., 01-03-2016, In : Journal of Heterocyclic Chemistry. 53, 2, p. 513-524 12 p.

Research output: Contribution to journalArticle

lissamine rhodamine B
Quinazolinones
Cytotoxins
Cytotoxicity
Amides
15 Citations (Scopus)
Halogens
MCF-7 Cells
Cells
Assays
Bromine

Pharmacophore modeling of delta and MU receptors and synthesis of enkephalines with D-[Leu] 5 C-terminal modification as delta selective agonists

Bhat, P., Mor, V., Muttineni, R., Pai, K. S. R., Chowdary, P. V. R. & Kota, S., 2012, In : International Journal of Pharmacy and Technology. 4, 2, p. 4350-4391 42 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice

Nigade, P. B., Gundu, J., Sreedhara Pai, K. & Nemmani, K. V. S., 01-10-2017, In : European Journal of Drug Metabolism and Pharmacokinetics. 42, 5, p. 835-847 13 p.

Research output: Contribution to journalArticle

Muscles
Organ Size
Skin
Brain
Pharmaceutical Preparations

Prediction of Tumor-to-Plasma Ratios of Basic Compounds in Subcutaneous Xenograft Mouse Models

Nigade, P. B., Gundu, J., Pai, K. S. & Nemmani, K. V. S., 01-06-2018, In : European Journal of Drug Metabolism and Pharmacokinetics. p. 1-16 16 p.

Research output: Contribution to journalArticle

Heterografts
Neoplasms
Oral Administration
Spleen
1 Citation (Scopus)

Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms

Nigade, P. B., Gundu, J., Pai, K. S., Nemmani, K. V. S. & Talwar, R., 04-05-2019, In : Xenobiotica. 49, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

Tissue
Organ Size
Tissue Distribution
Individuality
Rodentia
36 Citations (Scopus)
Cytotoxicity
Ascites
Tumors
Assays
Lymphoma