Mahadev Rao

BPharm, MPharm (Pharmacology), PhD

  • Department of Pharmacy Practice, Kasturba Hospital, Madhava Nagar

    567104 Manipal

    India

  • 3281 Citations
  • 31 h-Index
19982020

Research output per year

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Research Output

2020

Cannabinoids as an alternative option for conventional analgesics in cancer pain management: A pharmacogenomics perspective

Jose, A., Thomas, L., Baburaj, G., Munisamy, M. & Rao, M., 01-01-2020, In : Indian Journal of Palliative Care. 26, 1, p. 129-133 5 p.

Research output: Contribution to journalReview article

Open Access

Clinical Utility of HLA-B*58:01 Genotyping to Prevent Allopurinol-Induced SJS/TEN

Lavu, A., Thiriveedi, S., Thomas, L., Khera, K., Saravu, K. & Rao, M., 01-01-2020, (Accepted/In press) In : Hospital Pharmacy.

Research output: Contribution to journalArticle

Factors associated with outcomes in organophosphate and carbamate poisoning: a retrospective study

Reddy, B. S., Skaria, T. G., Polepalli, S., Vidyasagar, S., Rao, M., Kunhikatta, V., Nair, S. & Thunga, G., 01-07-2020, In : Toxicological Research.

Research output: Contribution to journalArticle

Histone demethylase KDM5B as a therapeutic target for cancer therapy

Jose, A., Shenoy, G. G., Rodrigues, G. S., Kumar, N. A. N., Munisamy, M., Thomas, L., Kolesar, J., Rai, G., Rao, P. P. N. & Rao, M., 08-2020, In : Cancers. 12, 8, p. 1-16 16 p., 2121.

Research output: Contribution to journalReview article

Open Access

Influence of single nucleotide polymorphisms on rifampin pharmacokinetics in tuberculosis patients

Thomas, L., Miraj, S. S., Surulivelrajan, M., Varma, M., Sanju, C. S. V. & Rao, M., 06-2020, In : Antibiotics. 9, 6, p. 1-15 15 p., 307.

Research output: Contribution to journalReview article

Open Access
2019

Adverse effects of fluoroquinolones: A retrospective cohort study in a South Indian tertiary healthcare facility

Mathews, B., Thalody, A. A., Miraj, S. S., Kunhikatta, V., Rao, M. & Saravu, K., 01-09-2019, In : Antibiotics. 8, 3, 104.

Research output: Contribution to journalArticle

Open Access

A Global Overview of Poison Treatment Apps and Databases

Poojari, P. G., Thunga, G., Nair, S., Kunhikatta, V. & Rao, M., 01-03-2019, In : International Journal of Toxicology. 38, 2, p. 146-153 8 p.

Research output: Contribution to journalReview article

Childhood Obesity and Diabetes: Role of Probiotics and PrebioticsGlobal Perspectives on Childhood Obesity

Vyas, N., Nair, S., Rao, M. & M, S. S., 2019, Global Perspectives on Childhood Obesity: Current Status, Consequences and Prevention. Bagchi, D. (ed.). 2 ed. Elsevier Inc., p. 363-376 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmacogenomics in palliative medicine

Rao, M., 01-04-2019, In : Indian Journal of Palliative Care. 25, 2, p. 169-171 3 p.

Research output: Contribution to journalEditorial

Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain

Polepalli, S., George, S. M., Valli Sri Vidya, R., Rodrigues, G. S., Ramachandra, L., Chandrashekar, R., M, D. N., Rao, P. P. N., Pestell, R. G. & Rao, M., 01-09-2019, In : International Journal of Biochemistry and Cell Biology. 114, 105558.

Research output: Contribution to journalReview article

2 Citations (Scopus)
1 Citation (Scopus)
2018

Benefits of Vitamin D in Sport Nutrition

M, S. S., Thunga, G. P., K, V., Rao, M. & Nair, S., 2018, Nutrition and Enhanced Sports Performance: Muscle Building, Endurance and Strength. Bagchi, D., Nair, S. & Sen, C. K. (eds.). 2 ed. Elsevier Inc., p. 497-508 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Targeting Prediabetes to Preempt Diabetes

Nair, S., Rao, M. & M, S. S., 20-06-2018, Nutritional and therapeutic intervention of diabetes and metabolic syndrome. Bagchi, D. & Nair, S. (eds.). 2 ed. Elsevier Inc., p. 33-41 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

ASXL3 is a novel pluripotency factor in human respiratory epithelial cells and a potential therapeutic target in small cell lung cancer

Shukla, V., Rao, M., Zhang, H., Beers, J., Wangsa, D., Wangsa, D., Buishand, F. O., Wang, Y., Yu, Z., Stevenson, H. S., Reardon, E. S., McLoughlin, K. C., Kaufman, A. S., Payabyab, E. C., Hong, J. A., Zhang, M., Davis, S., Edelman, D., Chen, G., Miettinen, M. M. & 4 others, Restifo, N. P., Ried, T., Meltzer, P. A. & Schrump, D. S., 15-11-2017, In : Cancer Research. 77, 22, p. 6267-6281 15 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Mithramycin depletes specificity protein 1 and activates p53 to mediate senescence and apoptosis of malignant pleural mesothelioma cells

Rao, M., Atay, S. M., Shukla, V., Hong, Y., Upham, T., Ripley, R. T., Hong, J. A., Zhang, M., Reardon, E., Fetsch, P., Miettinen, M., Li, X., Peer, C. J., Sissung, T., Figg, W. D., De Rienzo, A., Bueno, R. & Schrump, D. S., 01-03-2016, In : Clinical Cancer Research. 22, 5, p. 1197-1210 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy

Sukumar, M., Liu, J., Mehta, G. U., Patel, S. J., Roychoudhuri, R., Crompton, J. G., Klebanoff, C. A., Ji, Y., Li, P., Yu, Z., Whitehill, G. D., Clever, D., Eil, R. L., Palmer, D. C., Mitra, S., Rao, M., Keyvanfar, K., Schrump, D. S., Wang, E., Marincola, F. M. & 5 others, Gattinoni, L., Leonard, W. J., Muranski, P., Finkel, T. & Restifo, N. P., 12-01-2016, In : Cell Metabolism. 23, 1, p. 63-76 14 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)
2014

A novel murine T-cell receptor targeting NY-ESO-1

Rosati, S. F., Parkhurst, M. R., Hong, Y., Zheng, Z., Feldman, S. A., Rao, M., Abate-Daga, D., Beard, R. E., Xu, H., Black, M. A., Robbins, P. F., Schrump, D. A., Rosenberg, S. A. & Morgan, R. A., 2014, In : Journal of Immunotherapy. 37, 3, p. 135-146 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas

Zhang, Y., Calado, R., Rao, M., Hong, J. A., Meeker, A. K., Dumitriu, B., Atay, S., McCormick, P. J., Garfield, S. H., Wangsa, D., Padilla-Nash, H. M., Burkett, S., Zhang, M., Kunst, T. F., Peterson, N. R., Xi, S., Inchauste, S., Altorki, N. K., Casson, A. G., Beer, D. G. & 4 others, Harris, C. C., Ried, T., Young, N. S. & Schrump, D. S., 01-07-2014, In : PLoS One. 9, 7, e101010.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice

Peer, C. J., Rao, M., Spencer, S. D., Shahbazi, S., Steeg, P. S., Schrump, D. S. & Figg, W. D., 05-05-2013, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 927, p. 142-146 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

BACH2 represses effector programs to stabilize T reg-mediated immune homeostasis

Roychoudhuri, R., Hirahara, K., Mousavi, K., Clever, D., Klebanoff, C. A., Bonelli, M., Sciumè, G., Zare, H., Vahedi, G., Dema, B., Yu, Z., Liu, H., Takahashi, H., Rao, M., Muranski, P., Crompton, J. G., Punkosdy, G., Bedognetti, D., Wang, E., Hoffmann, V. & 10 others, Rivera, J., Marincola, F. M., Nakamura, A., Sartorelli, V., Kanno, Y., Gattinoni, L., Muto, A., Igarashi, K., O'Shea, J. J. & Restifo, N. P., 2013, In : Nature. 498, 7455, p. 506-510 5 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)
2012

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice

Portal-Nunẽz, S., Shankavaram, U. T., Rao, M., Datrice, N., Atay, S., Aparicio, M., Camphausen, K. A., Fernández-Salguero, P. M., Chang, H., Lin, P., Schrump, D. S., Garantziotis, S., Cuttitta, F. & Zudaire, E., 15-11-2012, In : Cancer Research. 72, 22, p. 5790-5800 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells

Zhang, M., Mathur, A., Zhang, Y., Xi, S., Atay, S., Hong, J. A., Datrice, N., Upham, T., Kemp, C. D., Ripley, R. T., Wiegand, G., Avital, I., Fetsch, P., Mani, H., Zlott, D., Robey, R., Bates, S. E., Li, X., Rao, M. & Schrump, D. S., 15-08-2012, In : Cancer Research. 72, 16, p. 4178-4192 15 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Polycomb repressor complex-2 is a novel target for mesothelioma therapy

Kemp, C. D., Rao, M., Xi, S., Inchauste, S., Mani, H., Fetsch, P., Filie, A., Zhang, M., Hong, J. A., Walker, R. L., Zhu, Y. J., Taylor Ripley, R., Mathur, A., Liu, F., Yang, M., Meltzer, P. A., Marquez, V. E., De Rienzo, A., Bueno, R. & Schrump, D. S., 01-01-2012, In : Clinical Cancer Research. 18, 1, p. 77-90 14 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2011

A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer

Chinnasamy, N., Wargo, J. A., Yu, Z., Rao, M., Frankel, T. L., Riley, J. P., Hong, J. J., Parkhurst, M. R., Feldman, S. A., Schrump, D. S., Restifo, N. P., Robbins, P. F., Rosenberg, S. A. & Morgan, R. A., 15-01-2011, In : Journal of Immunology. 186, 2, p. 685-696 12 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: Implications for adoptive immunotherapy of cancer

Rao, M., Chinnasamy, N., Hong, J. A., Zhang, Y., Zhang, M., Xi, S., Liu, F., Marquez, V. E., Morgan, R. A. & Schrump, D. S., 15-06-2011, In : Cancer Research. 71, 12, p. 4192-4204 13 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8 + T cells

Ji, Y., Pos, Z., Rao, M., Klebanoff, C. A., Yu, Z., Sukumar, M., Reger, R. N., Palmer, D. C., Borman, Z. A., Muranski, P., Wang, E., Schrump, D. S., Marincola, F. M., Restifo, N. P. & Gattinoni, L., 12-2011, In : Nature Immunology. 12, 12, p. 1230-1237 8 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)
2010

Cigarette smoke induces C/EBP-β-mediated activation of mir-31 in normal human respiratory epithelia and lung cancer cells

Xi, S., Yang, M., Tao, Y., Xu, H., Shan, J., Inchauste, S., Zhang, M., Mercedes, L., Hong, J. A., Rao, M. & Schrump, D. S., 2010, In : PLoS One. 5, 10, e13764.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

Liu, F., Killian, J. K., Yang, M., Walker, R. L., Hong, J. A., Zhang, M., Davis, S., Zhang, Y., Hussain, M., Xi, S., Rao, M., Meltzer, P. A. & Schrump, D. S., 24-06-2010, In : Oncogene. 29, 25, p. 3650-3664 15 p.

Research output: Contribution to journalArticle

188 Citations (Scopus)

Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD

Cheema, A., Knights, C. D., Rao, M., Catania, J., Perez, R., Simons, B., Dakshanamurthy, S., Kolukula, V. K., Tilli, M., Furth, P. A., Albanese, C. & Avantaggiati, M. L., 2010, In : Journal of Cellular Physiology. 225, 2, p. 371-384 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2009

Tobacco smoke induces polyeomb-mediated repression of Dickkopf-1 in lung cancer cells

Hussain, M., Rao, M., Humphries, A. E., Hong, J. A., Liu, F., Yang, M., Caragacianu, D. & Sehrump, D. S., 15-04-2009, In : Cancer Research. 69, 8, p. 3570-3578 9 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)
2008

Aurora A, aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

Zhang, X. H., Rao, M., Loprieato, J. A., Hong, J. A., Zhao, M., Chen, G. Z., Humphries, A. E., Nguyen, D. M., Trepel, J. B., Yu, X. & Schrump, D. S., 01-09-2008, In : Cancer Biology and Therapy. 7, 9, p. 1390-1399 10 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

Zhang, X. H., Rao, M., Loprieato, J. A., Hong, J. A., Zhao, M., Chen, G. Z., Humphries, A. E., Nguyen, D. M., Trepel, J. B., Yu, X. & Schrump, D. S., 09-2008, In : Cancer Biology and Therapy. 7, 9, p. 1388-1397 10 p.

Research output: Contribution to journalArticle

ErbB2 induces Notch1 activity and function in breast cancer cells

Lindsay, J., Jiao, X., Sakamaki, T., Casimiro, M. C., Shirley, L. A., Tran, T. H., Ju, X., Liu, M., Li, Z., Wang, C., Katiyar, S., Rao, M., Allen, K. G., Glazer, R. I., Ge, C., Stanley, P., Lisanti, M. P., Rui, H. & Pestell, R. G., 2008, In : Clinical and Translational Science. 1, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Inhibition of cyclin D1 gene transcription by Brg-1

Rao, M., Casimiro, M. C., Lisanti, M. P., D'Amico, M., Wang, C., Shirley, L. A., Leader, J. E., Liu, M., Stallcup, M., Engel, D. A., Murphy, D. J. & Pestell, R. G., 01-03-2008, In : Cell Cycle. 7, 5, p. 647-655 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2007

Breast cancer cell proliferation is inhibited by BAD: Regulation of cyclin D1

Fernando, R., Foster, J. S., Bible, A., Ström, A., Pestell, R. G., Rao, M., Saxton, A., Seung, J. B., Yamaguchi, K., Donnell, R., Cekanova, M. & Wimalasena, J., 28-09-2007, In : Journal of Biological Chemistry. 282, 39, p. 28864-28873 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth

Wu, K., Liu, M., Li, A., Donninger, H., Rao, M., Jiao, X., Lisanti, M. P., Cvekl, A., Birrer, M. & Pestell, R. G., 03-2007, In : Molecular Biology of the Cell. 18, 3, p. 755-767 13 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34

Carlson, B. A., Moustafa, M. E., Sengupta, A., Schweizer, U., Shrimali, R., Rao, M., Zhong, N., Wang, S., Feigenbaum, L., Byeong, J. L., Gladyshev, V. N. & Hatfield, D. L., 09-11-2007, In : Journal of Biological Chemistry. 282, 45, p. 32591-32602 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2006

3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor- and promotes adipocyte differentiation

Yin, Y., Yuan, H., Wang, C., Pattabiraman, N., Rao, M., Pestell, R. G. & Glazer, R. I., 02-2006, In : Molecular Endocrinology. 20, 2, p. 268-278 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth

Wu, K., Li, A., Rao, M., Liu, M., Dailey, V., Yang, Y., Di Vizio, D., Wang, C., Lisanti, M. P., Sauter, G., Russell, R. G., Cvekl, A. & Pestell, R. G., 10-2006, In : Molecular and Cellular Biology. 26, 19, p. 7116-7129 14 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

The molecular basis of vitamin D receptor and β-catenin crossregulation

Shah, S., Islam, M. N., Dakshanamurthy, S., Rizvi, I., Rao, M., Herrell, R., Zinser, G., Valrance, M., Aranda, A., Moras, D., Norman, A., Welsh, J. E. & Byers, S. W., 17-03-2006, In : Molecular Cell. 21, 6, p. 799-809 11 p.

Research output: Contribution to journalArticle

201 Citations (Scopus)

The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation (DOI: 10.1016/j.molcel.2006.01.037)

Shah, S., Islam, M. N., Dakshanamurthy, S., Rizvi, I., Rao, M., Herrell, R., Zinser, G., Valrance, M., Aranda, A., Moras, D., Norman, A., Welsh, J. E. & Byers, S. W., 07-04-2006, In : Molecular Cell. 22, 1, 1 p.

Research output: Contribution to journalComment/debate

The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

Di Giovanni, S., Knights, C. D., Rao, M., Yakovlev, A., Beers, J., Catania, J., Avantaggiati, M. L. & Faden, A. I., 06-09-2006, In : EMBO Journal. 25, 17, p. 4084-4096 13 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)
2005

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor α activity

Wang, C., Fan, S., Li, Z., Fu, M., Rao, M., Ma, Y., Lisanti, M. P., Albanese, C., Katzenellenbogen, B. S., Kushner, P. J., Weber, B., Rosen, E. M. & Pestell, R. G., 01-08-2005, In : Cancer Research. 65, 15, p. 6557-6567 11 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Cyclin D1 inhibits peroxisome proliferator-activated receptor γ-mediated adipogenesis through histone deacetylase recruitment

Fu, M., Rao, M., Bouras, T., Wang, C., Wu, K., Zhang, X., Li, Z., Yao, T. P. & Pestell, R. G., 29-04-2005, In : Journal of Biological Chemistry. 280, 17, p. 16934-16941 8 p.

Research output: Contribution to journalArticle

211 Citations (Scopus)

Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism

Fu, M., Wang, C., Rao, M., Wu, X., Bouras, T., Zhang, X., Li, Z., Jiao, X., Yang, J., Li, A., Perkins, N. D., Thimmapaya, B., Kung, A. L., Munoz, A., Giordano, A., Lisanti, M. P. & Pestell, R. G., 19-08-2005, In : Journal of Biological Chemistry. 280, 33, p. 29728-29742 15 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Erratum: Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice (Molecular and Cellular Biology 24:17 (7598-7611))

Hulit, J., Wang, C., Li, Z., Albanese, C., Rao, M., Di Vizio, D., Shah, S., Byers, S. W., Mahmood, R., Augenlicht, L. H., Russell, R. & Pestell, R. G., 01-2005, In : Molecular and Cellular Biology. 25, 1, 1 p.

Research output: Contribution to journalComment/debate

Selenocysteine tRNA identification in the model organisms Dictyostelium discoideum and Tetrahymena thermophila

Shrimali, R. K., Lobanov, A. V., Xu, X. M., Rao, M., Carlson, B. A., Mahadeo, D. C., Parent, C. A., Gladyshev, V. N. & Hatfield, D. L., 01-04-2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 147-151 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2004

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

Hulit, J., Wang, C., Li, Z., Albanese, C., Rao, M., Di Vizio, D., Shah, S., Byers, S. W., Mahmood, R., Augenlicht, L. H., Russell, R. & Pestell, R. G., 09-2004, In : Molecular and Cellular Biology. 24, 17, p. 7598-7611 14 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)