Mahadev Rao

BPharm, MPharm (Pharmacology), PhD

  • Department of Pharmacy Practice, Kasturba Hospital, Madhava Nagar

    567104 Manipal

    India

  • 3267 Citations
  • 31 h-Index
19982020

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Article
2020

Clinical Utility of HLA-B*58:01 Genotyping to Prevent Allopurinol-Induced SJS/TEN

Lavu, A., Thiriveedi, S., Thomas, L., Khera, K., Saravu, K. & Rao, M., 01-01-2020, (Accepted/In press) In : Hospital Pharmacy.

Research output: Contribution to journalArticle

Factors associated with outcomes in organophosphate and carbamate poisoning: a retrospective study

Reddy, B. S., Skaria, T. G., Polepalli, S., Vidyasagar, S., Rao, M., Kunhikatta, V., Nair, S. & Thunga, G., 01-01-2020, (Accepted/In press) In : Toxicological Research.

Research output: Contribution to journalArticle

2019

Adverse effects of fluoroquinolones: A retrospective cohort study in a South Indian tertiary healthcare facility

Mathews, B., Thalody, A. A., Miraj, S. S., Kunhikatta, V., Rao, M. & Saravu, K., 01-09-2019, In : Antibiotics. 8, 3, 104.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018
2017

ASXL3 is a novel pluripotency factor in human respiratory epithelial cells and a potential therapeutic target in small cell lung cancer

Shukla, V., Rao, M., Zhang, H., Beers, J., Wangsa, D., Wangsa, D., Buishand, F. O., Wang, Y., Yu, Z., Stevenson, H. S., Reardon, E. S., McLoughlin, K. C., Kaufman, A. S., Payabyab, E. C., Hong, J. A., Zhang, M., Davis, S., Edelman, D., Chen, G., Miettinen, M. M. & 4 others, Restifo, N. P., Ried, T., Meltzer, P. A. & Schrump, D. S., 15-11-2017, In : Cancer Research. 77, 22, p. 6267-6281 15 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Mithramycin depletes specificity protein 1 and activates p53 to mediate senescence and apoptosis of malignant pleural mesothelioma cells

Rao, M., Atay, S. M., Shukla, V., Hong, Y., Upham, T., Ripley, R. T., Hong, J. A., Zhang, M., Reardon, E., Fetsch, P., Miettinen, M., Li, X., Peer, C. J., Sissung, T., Figg, W. D., De Rienzo, A., Bueno, R. & Schrump, D. S., 01-03-2016, In : Clinical Cancer Research. 22, 5, p. 1197-1210 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy

Sukumar, M., Liu, J., Mehta, G. U., Patel, S. J., Roychoudhuri, R., Crompton, J. G., Klebanoff, C. A., Ji, Y., Li, P., Yu, Z., Whitehill, G. D., Clever, D., Eil, R. L., Palmer, D. C., Mitra, S., Rao, M., Keyvanfar, K., Schrump, D. S., Wang, E., Marincola, F. M. & 5 others, Gattinoni, L., Leonard, W. J., Muranski, P., Finkel, T. & Restifo, N. P., 12-01-2016, In : Cell Metabolism. 23, 1, p. 63-76 14 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)
2014

A novel murine T-cell receptor targeting NY-ESO-1

Rosati, S. F., Parkhurst, M. R., Hong, Y., Zheng, Z., Feldman, S. A., Rao, M., Abate-Daga, D., Beard, R. E., Xu, H., Black, M. A., Robbins, P. F., Schrump, D. A., Rosenberg, S. A. & Morgan, R. A., 2014, In : Journal of Immunotherapy. 37, 3, p. 135-146 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas

Zhang, Y., Calado, R., Rao, M., Hong, J. A., Meeker, A. K., Dumitriu, B., Atay, S., McCormick, P. J., Garfield, S. H., Wangsa, D., Padilla-Nash, H. M., Burkett, S., Zhang, M., Kunst, T. F., Peterson, N. R., Xi, S., Inchauste, S., Altorki, N. K., Casson, A. G., Beer, D. G. & 4 others, Harris, C. C., Ried, T., Young, N. S. & Schrump, D. S., 01-07-2014, In : PLoS One. 9, 7, e101010.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice

Peer, C. J., Rao, M., Spencer, S. D., Shahbazi, S., Steeg, P. S., Schrump, D. S. & Figg, W. D., 05-05-2013, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 927, p. 142-146 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

BACH2 represses effector programs to stabilize T reg-mediated immune homeostasis

Roychoudhuri, R., Hirahara, K., Mousavi, K., Clever, D., Klebanoff, C. A., Bonelli, M., Sciumè, G., Zare, H., Vahedi, G., Dema, B., Yu, Z., Liu, H., Takahashi, H., Rao, M., Muranski, P., Crompton, J. G., Punkosdy, G., Bedognetti, D., Wang, E., Hoffmann, V. & 10 others, Rivera, J., Marincola, F. M., Nakamura, A., Sartorelli, V., Kanno, Y., Gattinoni, L., Muto, A., Igarashi, K., O'Shea, J. J. & Restifo, N. P., 2013, In : Nature. 498, 7455, p. 506-510 5 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)
2012

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice

Portal-Nunẽz, S., Shankavaram, U. T., Rao, M., Datrice, N., Atay, S., Aparicio, M., Camphausen, K. A., Fernández-Salguero, P. M., Chang, H., Lin, P., Schrump, D. S., Garantziotis, S., Cuttitta, F. & Zudaire, E., 15-11-2012, In : Cancer Research. 72, 22, p. 5790-5800 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells

Zhang, M., Mathur, A., Zhang, Y., Xi, S., Atay, S., Hong, J. A., Datrice, N., Upham, T., Kemp, C. D., Ripley, R. T., Wiegand, G., Avital, I., Fetsch, P., Mani, H., Zlott, D., Robey, R., Bates, S. E., Li, X., Rao, M. & Schrump, D. S., 15-08-2012, In : Cancer Research. 72, 16, p. 4178-4192 15 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Polycomb repressor complex-2 is a novel target for mesothelioma therapy

Kemp, C. D., Rao, M., Xi, S., Inchauste, S., Mani, H., Fetsch, P., Filie, A., Zhang, M., Hong, J. A., Walker, R. L., Zhu, Y. J., Taylor Ripley, R., Mathur, A., Liu, F., Yang, M., Meltzer, P. A., Marquez, V. E., De Rienzo, A., Bueno, R. & Schrump, D. S., 01-01-2012, In : Clinical Cancer Research. 18, 1, p. 77-90 14 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2011

A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer

Chinnasamy, N., Wargo, J. A., Yu, Z., Rao, M., Frankel, T. L., Riley, J. P., Hong, J. J., Parkhurst, M. R., Feldman, S. A., Schrump, D. S., Restifo, N. P., Robbins, P. F., Rosenberg, S. A. & Morgan, R. A., 15-01-2011, In : Journal of Immunology. 186, 2, p. 685-696 12 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: Implications for adoptive immunotherapy of cancer

Rao, M., Chinnasamy, N., Hong, J. A., Zhang, Y., Zhang, M., Xi, S., Liu, F., Marquez, V. E., Morgan, R. A. & Schrump, D. S., 15-06-2011, In : Cancer Research. 71, 12, p. 4192-4204 13 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8 + T cells

Ji, Y., Pos, Z., Rao, M., Klebanoff, C. A., Yu, Z., Sukumar, M., Reger, R. N., Palmer, D. C., Borman, Z. A., Muranski, P., Wang, E., Schrump, D. S., Marincola, F. M., Restifo, N. P. & Gattinoni, L., 12-2011, In : Nature Immunology. 12, 12, p. 1230-1237 8 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)
2010

Cigarette smoke induces C/EBP-β-mediated activation of mir-31 in normal human respiratory epithelia and lung cancer cells

Xi, S., Yang, M., Tao, Y., Xu, H., Shan, J., Inchauste, S., Zhang, M., Mercedes, L., Hong, J. A., Rao, M. & Schrump, D. S., 2010, In : PLoS One. 5, 10, e13764.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

Liu, F., Killian, J. K., Yang, M., Walker, R. L., Hong, J. A., Zhang, M., Davis, S., Zhang, Y., Hussain, M., Xi, S., Rao, M., Meltzer, P. A. & Schrump, D. S., 24-06-2010, In : Oncogene. 29, 25, p. 3650-3664 15 p.

Research output: Contribution to journalArticle

186 Citations (Scopus)

Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD

Cheema, A., Knights, C. D., Rao, M., Catania, J., Perez, R., Simons, B., Dakshanamurthy, S., Kolukula, V. K., Tilli, M., Furth, P. A., Albanese, C. & Avantaggiati, M. L., 2010, In : Journal of Cellular Physiology. 225, 2, p. 371-384 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2009

Tobacco smoke induces polyeomb-mediated repression of Dickkopf-1 in lung cancer cells

Hussain, M., Rao, M., Humphries, A. E., Hong, J. A., Liu, F., Yang, M., Caragacianu, D. & Sehrump, D. S., 15-04-2009, In : Cancer Research. 69, 8, p. 3570-3578 9 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)
2008

Aurora A, aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

Zhang, X. H., Rao, M., Loprieato, J. A., Hong, J. A., Zhao, M., Chen, G. Z., Humphries, A. E., Nguyen, D. M., Trepel, J. B., Yu, X. & Schrump, D. S., 01-09-2008, In : Cancer Biology and Therapy. 7, 9, p. 1390-1399 10 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

Zhang, X. H., Rao, M., Loprieato, J. A., Hong, J. A., Zhao, M., Chen, G. Z., Humphries, A. E., Nguyen, D. M., Trepel, J. B., Yu, X. & Schrump, D. S., 09-2008, In : Cancer Biology and Therapy. 7, 9, p. 1388-1397 10 p.

Research output: Contribution to journalArticle

ErbB2 induces Notch1 activity and function in breast cancer cells

Lindsay, J., Jiao, X., Sakamaki, T., Casimiro, M. C., Shirley, L. A., Tran, T. H., Ju, X., Liu, M., Li, Z., Wang, C., Katiyar, S., Rao, M., Allen, K. G., Glazer, R. I., Ge, C., Stanley, P., Lisanti, M. P., Rui, H. & Pestell, R. G., 2008, In : Clinical and Translational Science. 1, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Inhibition of cyclin D1 gene transcription by Brg-1

Rao, M., Casimiro, M. C., Lisanti, M. P., D'Amico, M., Wang, C., Shirley, L. A., Leader, J. E., Liu, M., Stallcup, M., Engel, D. A., Murphy, D. J. & Pestell, R. G., 01-03-2008, In : Cell Cycle. 7, 5, p. 647-655 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2007

Breast cancer cell proliferation is inhibited by BAD: Regulation of cyclin D1

Fernando, R., Foster, J. S., Bible, A., Ström, A., Pestell, R. G., Rao, M., Saxton, A., Seung, J. B., Yamaguchi, K., Donnell, R., Cekanova, M. & Wimalasena, J., 28-09-2007, In : Journal of Biological Chemistry. 282, 39, p. 28864-28873 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth

Wu, K., Liu, M., Li, A., Donninger, H., Rao, M., Jiao, X., Lisanti, M. P., Cvekl, A., Birrer, M. & Pestell, R. G., 03-2007, In : Molecular Biology of the Cell. 18, 3, p. 755-767 13 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34

Carlson, B. A., Moustafa, M. E., Sengupta, A., Schweizer, U., Shrimali, R., Rao, M., Zhong, N., Wang, S., Feigenbaum, L., Byeong, J. L., Gladyshev, V. N. & Hatfield, D. L., 09-11-2007, In : Journal of Biological Chemistry. 282, 45, p. 32591-32602 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2006

3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor- and promotes adipocyte differentiation

Yin, Y., Yuan, H., Wang, C., Pattabiraman, N., Rao, M., Pestell, R. G. & Glazer, R. I., 02-2006, In : Molecular Endocrinology. 20, 2, p. 268-278 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth

Wu, K., Li, A., Rao, M., Liu, M., Dailey, V., Yang, Y., Di Vizio, D., Wang, C., Lisanti, M. P., Sauter, G., Russell, R. G., Cvekl, A. & Pestell, R. G., 10-2006, In : Molecular and Cellular Biology. 26, 19, p. 7116-7129 14 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

The molecular basis of vitamin D receptor and β-catenin crossregulation

Shah, S., Islam, M. N., Dakshanamurthy, S., Rizvi, I., Rao, M., Herrell, R., Zinser, G., Valrance, M., Aranda, A., Moras, D., Norman, A., Welsh, J. E. & Byers, S. W., 17-03-2006, In : Molecular Cell. 21, 6, p. 799-809 11 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)

The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

Di Giovanni, S., Knights, C. D., Rao, M., Yakovlev, A., Beers, J., Catania, J., Avantaggiati, M. L. & Faden, A. I., 06-09-2006, In : EMBO Journal. 25, 17, p. 4084-4096 13 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)
2005

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor α activity

Wang, C., Fan, S., Li, Z., Fu, M., Rao, M., Ma, Y., Lisanti, M. P., Albanese, C., Katzenellenbogen, B. S., Kushner, P. J., Weber, B., Rosen, E. M. & Pestell, R. G., 01-08-2005, In : Cancer Research. 65, 15, p. 6557-6567 11 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Cyclin D1 inhibits peroxisome proliferator-activated receptor γ-mediated adipogenesis through histone deacetylase recruitment

Fu, M., Rao, M., Bouras, T., Wang, C., Wu, K., Zhang, X., Li, Z., Yao, T. P. & Pestell, R. G., 29-04-2005, In : Journal of Biological Chemistry. 280, 17, p. 16934-16941 8 p.

Research output: Contribution to journalArticle

211 Citations (Scopus)

Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism

Fu, M., Wang, C., Rao, M., Wu, X., Bouras, T., Zhang, X., Li, Z., Jiao, X., Yang, J., Li, A., Perkins, N. D., Thimmapaya, B., Kung, A. L., Munoz, A., Giordano, A., Lisanti, M. P. & Pestell, R. G., 19-08-2005, In : Journal of Biological Chemistry. 280, 33, p. 29728-29742 15 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Selenocysteine tRNA identification in the model organisms Dictyostelium discoideum and Tetrahymena thermophila

Shrimali, R. K., Lobanov, A. V., Xu, X. M., Rao, M., Carlson, B. A., Mahadeo, D. C., Parent, C. A., Gladyshev, V. N. & Hatfield, D. L., 01-04-2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 147-151 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2004

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

Hulit, J., Wang, C., Li, Z., Albanese, C., Rao, M., Di Vizio, D., Shah, S., Byers, S. W., Mahmood, R., Augenlicht, L. H., Russell, R. & Pestell, R. G., 09-2004, In : Molecular and Cellular Biology. 24, 17, p. 7598-7611 14 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase

Carlson, B. A., Xu, X. M., Kryukov, G. V., Rao, M., Berry, M. J., Gladyshev, V. N. & Hatfield, D. L., 31-08-2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 35, p. 12848-12853 6 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)

The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity

Fu, M., Rao, M., Wu, K., Wang, C., Zhang, X., Hessien, M., Yeung, Y. G., Gioeli, D., Weber, M. J. & Pestell, R. G., 09-07-2004, In : Journal of Biological Chemistry. 279, 28, p. 29436-29449 14 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements

D'Amico, M., Wu, K., Fu, M., Rao, M., Albanese, C., Russell, R. G., Lian, H., Bregman, D., White, M. A. & Pestell, R. G., 15-06-2004, In : Cancer Research. 64, 12, p. 4122-4130 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2003

Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

Fu, M., Rao, M., Wang, C., Sakamaki, T., Wang, J., Di Vizio, D., Zhang, X., Albanese, C., Balk, S., Chang, C., Fan, S., Rosen, E., Palvimo, J. J., Jänne, O. A., Muratoglu, S., Avantaggiati, M. L. & Pestell, R. G., 12-2003, In : Molecular and Cellular Biology. 23, 23, p. 8563-8575 13 p.

Research output: Contribution to journalArticle

202 Citations (Scopus)

Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec

Rao, M., Carlson, B. A., Novoselov, S. V., Weeks, D. P., Gladyshev, V. N. & Hatfield, D. L., 01-08-2003, In : RNA. 9, 8, p. 923-930 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Models for assessing the role of selenoproteins in health

Moustafa, M. E., Kumaraswamy, E., Zhong, N., Rao, M., Carlson, B. A. & Hatfield, D. L., 01-07-2003, In : Journal of Nutrition. 133, 7 SUPPL.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2002

Intratumoral administration of paclitaxel in an in situ gelling poloxamer 407 formulation

Amiji, M. M., Lai, P-K., Shenoy, D. B. & Rao, M., 2002, In : Pharmaceutical Development and Technology. 7, 2, p. 195-202 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii

Novoselov, S. V., Rao, M., Onoshko, N. V., Zhi, H., Kryukov, G. V., Xiang, Y., Weeks, D. P., Hatfield, D. L. & Gladyshev, V. N., 15-07-2002, In : EMBO Journal. 21, 14, p. 3681-3693 13 p.

Research output: Contribution to journalArticle

207 Citations (Scopus)
1999

In vitro and in vivo effects of phenolic antioxidants against cisplatin-induced nephrotoxicity

Rao, M. A., Kumar, M. M. & Rao, M. A., 1999, In : Journal of Biochemistry. 125, 2, p. 383-390 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
17 Citations (Scopus)
1998

Effect of Cisplatin on Total Protein in Rat Kidney Cortical Slices

Rao, M. & Rao, M. N. A., 1998, In : Indian Journal of Pharmaceutical Sciences. 60, 3, p. 132-135 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Gastroprotective effect of 1-phenyl-3-(4-hydroxy-3,5-di-tert-butylphenyl)prop-2-en-1-one in rats

Rao, P. N. P., Rao, M. & Rao, M., 1998, In : Journal of Pharmacy and Pharmacology. 50, 12, p. 1371-1375 5 p.

Research output: Contribution to journalArticle