• Madhav Nagar, MCOPS, Karnataka State

    576104 Manipal

    India

  • 1660 Citations
  • 23 h-Index
1988 …2019
If you made any changes in Pure these will be visible here soon.

Research Output 1988 2019

  • 1660 Citations
  • 23 h-Index
  • 129 Article
  • 3 Review article
  • 1 Comment/debate
  • 1 Letter
2019
1 Citation (Scopus)

Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In : Psychopharmacology. 236, 6, p. 1829-1838 10 p.

Research output: Contribution to journalArticle

Illness Behavior
Cannabinoid Receptors
Lipopolysaccharides
Oxidative Stress
Tumor Necrosis Factor-alpha

Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In : Biomedical Reports. 11, 2, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Catechin
Sprague Dawley Rats
Rats
Oxidative Stress

Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In : Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptors
Nervous System Diseases
Substance P
Neurokinin-1 Receptor Antagonists
Physiological Phenomena

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In : Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reperfusion
Ischemia
Celecoxib
Kidney

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

Silymarin
Liposomes
Wistar Rats
Alcohols
Biological Availability

Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In : Experimental Gerontology. 125, 1 p.

Research output: Contribution to journalArticle

Muscle
Locomotion
Gait
Pharmacology
Sarcopenia
10 Citations (Scopus)

Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In : Cytotechnology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Episodic Memory
Catechin
Memory Disorders
Cytotoxicity
Doxorubicin
1 Citation (Scopus)

Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In : Andrologia. 50, 7, e13037.

Research output: Contribution to journalArticle

Wistar Rats
Sexual Behavior
Spermatozoa
Aphrodisiacs
Sperm Count
7 Citations (Scopus)

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

Biswas, S. & Rao, C. M., 15-10-2018, In : European Journal of Pharmacology. 837, p. 8-24 17 p.

Research output: Contribution to journalReview article

Epigenomics
Neoplasms
Enzymes
Therapeutics
Chromatin
3 Citations (Scopus)

Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model

Gill, M., Kinra, M., Rai, A., Chamallamudi, M. R. & Kumar, N., 01-01-2018, In : NeuroReport. 29, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Antioxidants
Sucrose
Brain
Plant Bark

Evaluation of novel 3-hydroxyflavone analogues as HDAC inhibitors against colorectal cancer

Biswas, S., Reddy, N. D., Jayashree, B. S. & Rao, C. M., 01-01-2018, In : Advances in Pharmacological Sciences. 2018, 4751806.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Histone Deacetylases
Colorectal Neoplasms
Inhibitory Concentration 50
HCT116 Cells
4 Citations (Scopus)

Evaluation of the aphrodisiac potential of a chemically characterized aqueous extract of Tamarindus indica pulp

Rai, A., Das, S., Chamallamudi, M. R., Nandakumar, K., Shetty, R., Gill, M., Sumalatha, S., Devkar, R., Gourishetti, K. & Kumar, N., 10-01-2018, In : Journal of Ethnopharmacology. 210, p. 118-124 7 p.

Research output: Contribution to journalArticle

Tamarindus
Aphrodisiacs
Saponins
Phenol
Arousal
1 Citation (Scopus)

Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In : European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

Research output: Contribution to journalArticle

Interleukin-6
Lipopolysaccharides
Prostaglandin-Endoperoxide Synthases
Reactive Oxygen Species
Tarsal Joints
1 Citation (Scopus)

Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 07-03-2018, (Accepted/In press) In : Metabolic Brain Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

Purinergic P1 Receptor Antagonists
Cyclooxygenase Inhibitors
Haloperidol
Antipsychotic Agents
Caffeine
5 Citations (Scopus)

Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In : International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

Research output: Contribution to journalArticle

Chitosan
Nanoparticles
Pharmacodynamics
Pharmacokinetics
Pharmaceutical Preparations
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan
1 Citation (Scopus)

Naringin ameliorates doxorubicin-induced neurotoxicity in vitro and cognitive dysfunction in vivo

Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Mallik, S. B., Gourishetti, K., Hussain, S. M., Rao, C. M. & Nandakumar, K., 01-04-2018, In : Pharmacognosy Magazine. 14, 55, p. S197-S207

Research output: Contribution to journalArticle

Doxorubicin
Episodic Memory
Locomotion
Reactive Oxygen Species
Flow Cytometry
temozolomide
High Pressure Liquid Chromatography
Brain
formic acid
Pharmaceutical Preparations
2017
8 Citations (Scopus)

Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In : NeuroReport. 28, 9, p. 540-544 5 p.

Research output: Contribution to journalArticle

Dementia
Insulin
Rivastigmine
Frontal Lobe
Glucose
57 Citations (Scopus)

Epigenetics in cancer: Fundamentals and Beyond

Biswas, S. & Rao, C. M., 01-05-2017, In : Pharmacology and Therapeutics. 173, p. 118-134 17 p.

Research output: Contribution to journalReview article

Epigenomics
Neoplasms
Carcinogenesis
Histone Code
Gene Targeting
1 Citation (Scopus)

Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

Research output: Contribution to journalArticle

Carbon tetrachloride
Carbon Tetrachloride
Toxicants
Toxicity
Liver

Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

Wankhede, S., Kumar, N., Simon, L., Biswas, S., Gourishetti, K., Ramalingayya, G. V., Joshi, M. & Rao, C. M., 19-10-2017, In : EXCLI Journal. 16, p. 1150-1163 14 p.

Research output: Contribution to journalArticle

Chalcones
chalcones
Tumor Burden
breast neoplasms
Breast Neoplasms
2 Citations (Scopus)
Dementia
Rats
Insulin
Data storage equipment
Glucose
6 Citations (Scopus)
Chalcone
chalcone
Cell Cycle Checkpoints
colorectal neoplasms
Colonic Neoplasms
13 Citations (Scopus)

Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

Ramalingayya, G. V., Cheruku, S. P., Nayak, P. G., Kishore, A., Shenoy, R., Rao, M. & Krishnadas, N., 29-03-2017, In : Drug Design, Development and Therapy. 11, p. 1011-1026 16 p.

Research output: Contribution to journalArticle

Rutin
Memory Disorders
Doxorubicin
Wistar Rats
Neurites
1 Citation (Scopus)

Temozolomide and its stability—a critical factor

Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In : Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

Research output: Contribution to journalArticle

temozolomide
Drugs
drug
Degradation
Pharmaceutical Preparations
2016
9 Citations (Scopus)

An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

Reddy, N. D., Shoja, M. H., Biswas, S., Nayak, P. G., Kumar, N. & Rao, C. M., 25-06-2016, In : Chemico-Biological Interactions. 253, p. 112-124 13 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Sulfonamides
Human Activities
Cells
Histone Deacetylases
Aluminum
Curcumin
Aptitude
Water
Neurodegenerative Diseases
14 Citations (Scopus)

Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

Basu Mallik, S., Mudgal, J., Nampoothiri, M., Hall, S., Dukie, S. A., Grant, G., Rao, C. M. & Arora, D., 06-10-2016, In : Neuroscience Letters. 632, p. 218-223 6 p.

Research output: Contribution to journalArticle

Illness Behavior
Lipopolysaccharides
Brain
Oxidative Stress
Antioxidants
9 Citations (Scopus)
Pharmacists
Chronic Obstructive Pulmonary Disease
Quality of Life
India
Lung
1 Citation (Scopus)
5 Citations (Scopus)

Formulation and characterisation of nanosuspensions of BCS class II and IV drugs by combinative method

Attari, Z., Kalvakuntla, S., Reddy, M. S., Deshpande, M., Rao, C. M. & Koteshwara, K. B., 03-03-2016, In : Journal of Experimental Nanoscience. 11, 4, p. 276-288 13 p.

Research output: Contribution to journalArticle

Particle size
Ibuprofen
Ball milling
aprepitant
Pharmaceutical Preparations

In vitro and in vivo hepatoprotective action of L-α-phosphatidylcholine in alcohol-induced toxicity model

Raj, P. V., Mudgal, J., Reddy, N. D., Rao, C. M., Bansal, P., Rai, A. & Kumar, N., 01-11-2016, In : International Journal of Pharmaceutical Sciences Review and Research. 41, 1, p. 171-176 6 p., 33.

Research output: Contribution to journalArticle

Phosphatidylcholines
Silymarin
Alcohols
Sulfhydryl Compounds
Wistar Rats
2 Citations (Scopus)

In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer

Shoja, M. H., Reddy, N. D., Nayak, P. G., Biswas, S., Srinivasan, K. K. & Rao, C. M., 20-06-2016, In : Journal of Ethnopharmacology. 186, p. 159-168 10 p.

Research output: Contribution to journalArticle

Rutaceae
9,10-Dimethyl-1,2-benzanthracene
Breast Neoplasms
Matrix Metalloproteinases
Sprague Dawley Rats
2 Citations (Scopus)

In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In : Frontiers in Pharmacology. 7, OCT, 381.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Sucrose
Diet
Phosphorylation
23 Citations (Scopus)
Rutin
Episodic Memory
Memory Disorders
Scopolamine Hydrobromide
Long-Term Memory
2 Citations (Scopus)
Arthritis
Experimental Arthritis
Cytokines
Dinoprostone
Stomach
6 Citations (Scopus)

Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride

Jetti, R., Raghuveer, C. & Rao, M. C., 2016, In : Toxicology and Industrial Health. 32, 1, p. 183-187 5 p.

Research output: Contribution to journalArticle

Ginkgo biloba
Memory Disorders
Fluorides
Ascorbic Acid
Learning
18 Citations (Scopus)

Role of the drug transporter ABCC3 in breast cancer chemoresistance

Balaji, S. A., Udupa, N., Chamallamudi, M. R., Gupta, V. & Rangarajan, A., 01-05-2016, In : PLoS One. 11, 5, e0155013.

Research output: Contribution to journalArticle

breast neoplasms
transporters
Chemotherapy
Breast Neoplasms
drugs
5 Citations (Scopus)

Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study

Prasad, V. G., Reddy, N., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, M. C. & Shenoy, R., 07-2016, In : Pharmacognosy Magazine. 12, 47, p. S441-S445

Research output: Contribution to journalArticle

hydrazine
1,2-Dimethylhydrazine
Colonic Neoplasms
Aberrant Crypt Foci
Spices
4 Citations (Scopus)

Selected novel 5’-amino-2’-hydroxy-1, 3-diaryl-2- propen-1-ones arrest cell cycle of HCT-116 in G0/G1 phase

Simon, L., Srinivasan, K. K., Kumar, N., Reddy, N. D., Biswas, S., Mallikarjuna Rao, C. & Moorkoth, S., 13-01-2016, In : EXCLI Journal. 15, p. 21-32 12 p.

Research output: Contribution to journalArticle

HCT116 Cells
Cell Cycle Resting Phase
G1 Phase
Cell Cycle Checkpoints
interphase
3 Citations (Scopus)

Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In : Andrologia. 48, 10, p. 1236-1243 8 p.

Research output: Contribution to journalArticle

Aphrodisiacs
Wistar Rats
Oligospermia
Glass
Safety
3 Citations (Scopus)

Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In : Cytotechnology. 68, 6, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

Amikacin
Cytotoxicity
Tumors
Cells
Derivatives
2 Citations (Scopus)
temozolomide
formic acid
High Pressure Liquid Chromatography
Alkylating Agents
Glioblastoma
2015
5 Citations (Scopus)

Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In : Pharmacognosy Magazine. 11, 44, p. S296-S302

Research output: Contribution to journalArticle

Curcumin
Inflammatory Bowel Diseases
Interleukin-6
Tumor Necrosis Factor-alpha
Curcuma
26 Citations (Scopus)

Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In : International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

Research output: Contribution to journalArticle

Sun hoods
Sunscreening Agents
Radiation protection
Radiation Protection
Antioxidants
16 Citations (Scopus)

Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In : Journal of Ethnopharmacology. 168, p. 50-60 11 p.

Research output: Contribution to journalArticle

Rutaceae
Caspase 7
Cell Cycle Checkpoints
Caspase 3
Apoptosis
17 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

Sulfonamides
Caspase 7
Colon
Adenocarcinoma
Annexin A5
30 Citations (Scopus)
Simvastatin
Frontal Lobe
Aluminum
Hippocampus
Rivastigmine