• Madhav Nagar, MCOPS, Karnataka State

    576104 Manipal

    India

  • 1602 Citations
  • 22 h-Index
1988 …2019
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Research Output 1988 2019

  • 1602 Citations
  • 22 h-Index
  • 126 Article
  • 3 Review article
  • 1 Comment/debate
  • 1 Letter
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Article
2014
7 Citations (Scopus)

Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In : The Scientific World Journal. 2014, 673248.

Research output: Contribution to journalArticle

Acetic Acid
acetic acid
Peroxidase
nitrite
Rats
15 Citations (Scopus)

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In : Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

Research output: Contribution to journalArticle

Tumors
Derivatives
Liquids
Cytotoxicity
Transferases
10 Citations (Scopus)

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In : Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Carrageenan
Cytokines
Inflammation
Dinoprostone
Rats
42 Citations (Scopus)

Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In : Pharmacological Reports. 66, 5, p. 788-798 11 p.

Research output: Contribution to journalArticle

Silymarin
Liposomes
Biological Availability
Hepatocytes
Acetaminophen
2 Citations (Scopus)
Clofibric Acid
Acetic Acid
Insulin Resistance
Insulin
Medical problems
4 Citations (Scopus)

The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In : Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

Research output: Contribution to journalArticle

Vernonia
Multiple Drug Resistance
Methylene Chloride
Epithelial Cells
Apoptosis
2013
2 Citations (Scopus)

Antioxidant and antihyperlipidemic activity of Melia azedarach Linn. extracts in rats

Vijaya Kumar, S., Sanghai, D. B., Mallikarjuna Rao, C. & Shreedhara, C. S., 2013, In : Research Journal of Pharmacy and Technology. 6, 11, p. 1195-1199 5 p.

Research output: Contribution to journalArticle

Melia azedarach
Hypolipidemic Agents
Antioxidants
Flavonoids
Inhibitory Concentration 50
1 Citation (Scopus)

A rat model against chemotherapy plus radiation-induced oral mucositis

Patel, A., Rajesh, S., Chandrashekhar, V. M., Rathnam, S., Shah, K., Mallikarjuna Rao, C. & Nandakumar, K., 10-2013, In : Saudi Pharmaceutical Journal. 21, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

Stomatitis
Radiation
Mucositis
Drug Therapy
Tongue
16 Citations (Scopus)
Catechin
Caspases
Hep G2 Cells
Liposomes
Biological Availability
34 Citations (Scopus)

Impact of caffeic acid on aluminium chloride-induced dementia in rats

Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In : Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

Research output: Contribution to journalArticle

Dementia
Brain
Acetylcholinesterase
Nitrites
Glutathione Transferase
14 Citations (Scopus)

In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In : Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Cisplatin
Neoplasms
Tumors
Bearings (structural)
9 Citations (Scopus)

Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In : Pharmacological Reports. 65, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

Dinitrochlorobenzene
Sesamum
Sulfasalazine
Nitrites
Inflammatory Bowel Diseases
7 Citations (Scopus)

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In : American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

Research output: Contribution to journalArticle

Xanthium
Neoplasms
Hexanes
Chloroform
lissamine rhodamine B
19 Citations (Scopus)

Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In : Lipids. 48, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Triglycerides
Cholesterol
Plasmas
Nutrition
7 Citations (Scopus)

The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

Raghu, J., Raghuveer, V. C., Rao, M. C., Somayaji, N. S. & Babu, P. B., 2013, In : Interdisciplinary Toxicology. 6, 4, p. 217-221 5 p.

Research output: Contribution to journalArticle

Ginkgo biloba
Memory Disorders
Fluorides
Ascorbic Acid
Learning
2012
4 Citations (Scopus)

Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In : Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

Xanthium
Chloroform
Hexanes
Mortality
Body Weight
5 Citations (Scopus)

Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In : Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

Research output: Contribution to journalArticle

Berberis
Ascites
Cisplatin
Carcinoma
Artemia
31 Citations (Scopus)

Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In : Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Cells
Derivatives
Ascites
Assays
3 Citations (Scopus)

Histological and physiochemical standardization of Melia azedarach. Linn bark

Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In : Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

Research output: Contribution to journalArticle

Melia azedarach
Sieves
Standardization
Phloem
Phytochemicals
2011
39 Citations (Scopus)

Ameliorative effect of caffeic acid against inflammatory pain in rodents

Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In : European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

Research output: Contribution to journalArticle

Rodentia
Pain
Analgesics
Nitrites
nimesulide
32 Citations (Scopus)

Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In : Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

Research output: Contribution to journalArticle

Terminalia
Anti-Inflammatory Agents
Freund's Adjuvant
Carrageenan
Inflammation
18 Citations (Scopus)

Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In : Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

Research output: Contribution to journalArticle

Quinoxalines
Anti-Inflammatory Agents
Antioxidants
Derivatives
Ricinoleic Acids
15 Citations (Scopus)

Development and validation of a HPLC method for quantification of rivastigmine in rat urine and identification of a novel metabolite in urine by LC-MS/MS

Arumugam, K., Chamallamudi, M. R., Gilibili, R. R., Mullangi, R., Ganesan, S., Kar, S. S., Averineni, R., Shavi, G. & Udupa, N., 03-2011, In : Biomedical Chromatography. 25, 3, p. 353-361 9 p.

Research output: Contribution to journalArticle

Rivastigmine
Metabolites
Rats
High Pressure Liquid Chromatography
Urine
14 Citations (Scopus)

Effect of Dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats

Rao, M. C., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, G. N. & Shenoy, R. R., 09-2011, In : Molecular and Cellular Biochemistry. 355, 1-2, p. 249-256 8 p.

Research output: Contribution to journalArticle

Curcumin
Wound Healing
Dexamethasone
Rats
Wounds and Injuries
7 Citations (Scopus)

Effect of lecithin on d-galactosamine induced hepatotoxicity through mitochondrial pathway involving Bcl-2 and Bax

Raj, P. V., Nitesh, K., Prateek, J., Sankhe, M. N., Rao, J. V., Rao, C. M. & Udupa, N., 10-2011, In : Indian Journal of Clinical Biochemistry. 26, 4, p. 378-384 7 p.

Research output: Contribution to journalArticle

Galactosamine
Lecithins
Liver
Rats
Messenger RNA
8 Citations (Scopus)
Rivastigmine
Pharmacokinetics
Fluorescence
Brain
Liquid-Liquid Extraction
27 Citations (Scopus)

Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats

Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 27-01-2011, In : Journal of Ethnopharmacology. 133, 2, p. 608-612 5 p.

Research output: Contribution to journalArticle

Sesamum
Wound Healing
Dexamethasone
Protein-Lysine 6-Oxidase
Wounds and Injuries
1 Citation (Scopus)

Pro-healing effects of morin, a natural antioxidant, on normal and dexamethasone-impaired wounds

Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 12-2011, In : Journal of Basic and Clinical Physiology and Pharmacology. 22, 4, p. 131-135 5 p.

Research output: Contribution to journalArticle

Dexamethasone
Antioxidants
Wounds and Injuries
Granulation Tissue
Protein-Lysine 6-Oxidase
3 Citations (Scopus)

Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2,1,b]-benzothiazole derivatives

Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Mallikarjuna Rao, C. & Barve, A., 10-2011, In : Letters in Drug Design and Discovery. 8, 8, p. 717-724 8 p.

Research output: Contribution to journalArticle

MCF-7 Cells
Inhibitory Concentration 50
Neoplasms
In Vitro Techniques
benzothiazole

Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2, 1, b]-benzothiazole derivatives

Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Rao, M. C. & Barve, A., 11-2011, In : Letters in Drug Design and Discovery. 8, 9, p. 717-724 8 p.

Research output: Contribution to journalArticle

MCF-7 Cells
Inhibitory Concentration 50
Neoplasms
In Vitro Techniques
benzothiazole
2010
20 Citations (Scopus)

Anti-osteoporotic activity of the petroleum ether extract of Cissus quadrangularis Linn. in ovariectomized wistar rats

Potu, B. K., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Nayak, S. R. & Thomas, H., 2010, In : Chang Gung Medical Journal. 33, 3, p. 252-257 6 p.

Research output: Contribution to journalArticle

Cissus
Ovariectomy
Wistar Rats
Femur
Therapeutics
23 Citations (Scopus)

Antitumor and antioxidant activity of Polyalthia longifolia stem bark ethanol extract

Manjula, S. N., Kenganora, M., Parihar, V. K., Kumar, S., Nayak, P. G., Kumar, N., Ranganath Pai, K. S. & Rao, C. M., 2010, In : Pharmaceutical Biology. 48, 6, p. 690-696 7 p.

Research output: Contribution to journalArticle

Polyalthia
Ascites
Ethanol
Antioxidants
Inhibitory Concentration 50
12 Citations (Scopus)
Silymarin
Galactosamine
Lecithins
Toxicity
Rats
1 Citation (Scopus)

Free radical scavenging activity of extracts of young prop roots of ficus bengalensis

Nidhiya, I. S. R., Pai, K. S. R. & Mallikarjuna Rao, C., 2010, In : Pharmacologyonline. 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

Ficus
Free Radicals
Iron
Antioxidants
Moraceae
17 Citations (Scopus)

In vitro and in vivo hepatoprotective effects of the total alkaloid fraction of Hygrophila auriculata leaves

Raj, V. P., Chandrasekhar, R. H., Vijayan, P., Dhanaraj, S. A., Rao, M. C., Rao, V. J. & Nitesh, K., 01-03-2010, In : Indian Journal of Pharmacology. 42, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

Acanthaceae
Alkaloids
Hep G2 Cells
Hepatocytes
Body Weight
19 Citations (Scopus)

Protective role of catechin on D-galactosamine induced hepatotoxicity through a p53 dependent pathway

Vasanth Raj, P., Nitesh, K., Sagar Gang, S., Hitesh Jagani, V., Raghu Chandrashekhar, H., Venkata Rao, J., Mallikarjuna Rao, C. & Udupa, N., 2010, In : Indian Journal of Clinical Biochemistry. 25, 4, p. 349-356 8 p.

Research output: Contribution to journalArticle

Galactosamine
Catechin
Liver
Mitochondrial Membrane Potential
Enzyme activity
2009
19 Citations (Scopus)

Antidiabetic effect through islet cell protection in streptozotocin diabetes: A preliminary assessment of two thiazolidin-4-ones in Swiss albino mice

Kishore, A., Nampurath, G. K., Mathew, S. P., Zachariah, R. T., Potu, B. K., Rao, M. S., Valiathan, M. & Chamallamudi, M. R., 12-02-2009, In : Chemico-Biological Interactions. 177, 3, p. 242-246 5 p.

Research output: Contribution to journalArticle

Cytoprotection
Niacinamide
Experimental Diabetes Mellitus
Streptozocin
Medical problems
1 Citation (Scopus)

Effect of Berberis aristata on type I and II diabetes mellitus models in albino rats

Rameshwar, N. K., Shenoy, R. R., Sudheendra, A. T. & Rao, C. M., 2009, In : Pharmacologyonline. 1, p. 89-96 8 p.

Research output: Contribution to journalArticle

Berberis
Streptozocin
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Liver Glycogen
4 Citations (Scopus)

Evaluation of the healing potential of schrebera swietenioides in the dexamethasone-suppressed wound healing in rodents

Rasal, A. S., Nayak, P. G., Baburao, K., Shenoy, R. R. & Mallikarjuna Rao, C., 09-2009, In : International Journal of Lower Extremity Wounds. 8, 3, p. 147-152 6 p.

Research output: Contribution to journalArticle

Wound Healing
Dexamethasone
Granulation Tissue
Rodentia
Space Simulation
27 Citations (Scopus)

Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis

Potu, B. K., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Prasad, K., Nayak, S. R., Dharmavarapu, P. K., Kedage, V. & Bhat, K. M. R., 2009, In : Upsala Journal of Medical Sciences. 114, 3, p. 140-148 9 p.

Research output: Contribution to journalArticle

Cissus
Ovariectomy
Femur
Postmenopausal Osteoporosis
Osteoporosis
3 Citations (Scopus)

Gender differences in the pharmacokinetics of rivastigmine in rats

Arumugam, K., Chamallamudi, M. R., Mallayasamy, S. R., Ganesan, S., Shavi, G. V., Averineni, R., Reddy, R., Bhat, K. & Udupa, N., 2009, In : Arzneimittel-Forschung/Drug Research. 59, 10, p. 493-497 5 p.

Research output: Contribution to journalArticle

Rivastigmine
Pharmacokinetics
Area Under Curve
Gonadal Hormones
Intravenous Administration
7 Citations (Scopus)

Growth promoting potential of Ficus bengalensis root extracts in immature female rats

Nidhiya, I. S. R., Pai, K. S. R. & Rao, C. M., 04-2009, In : Pharmaceutical Biology. 47, 4, p. 268-273 6 p.

Research output: Contribution to journalArticle

Ficus
Alcohols
Growth
Moraceae
Growth Plate
34 Citations (Scopus)

Petroleum ether extract of cissus quadrangularis (linn.) enhances bone marrow mesenchymal stem cell proliferation and facilitates osteoblastogenesis

Potu, B. K., Bhat, K. M. R., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Nayak, S. R. & Muttigi, M. S., 2009, In : Clinics. 64, 10, p. 993-998 6 p.

Research output: Contribution to journalArticle

Cissus
Mesenchymal Stromal Cells
Bone Marrow
Cell Proliferation
Extracellular Matrix
100 Citations (Scopus)

Synthesis and antitumor activity of optically active thiourea and their 2-aminobenzothiazole derivatives: A novel class of anticancer agents

Manjula, S. N., Malleshappa Noolvi, N., Vipan Parihar, K., Manohara Reddy, S. A., Ramani, V., Gadad, A. K., Singh, G., Gopalan Kutty, N. & Mallikarjuna Rao, C., 07-2009, In : European Journal of Medicinal Chemistry. 44, 7, p. 2923-2929 7 p.

Research output: Contribution to journalArticle

Thiourea
Cytotoxicity
Ascites
Antineoplastic Agents
Inhibitory Concentration 50
26 Citations (Scopus)

Vasorelaxant effect in rat aortic rings through calcium channel blockage: A preliminary in vitro assessment of a 1,3,4-oxadiazole derivative

Bankar, G. R., Nandakumar, K., Nayak, P. G., Thakur, A., Chamallamudi, M. R. & Nampurath, G. K., 30-10-2009, In : Chemico-Biological Interactions. 181, 3, p. 377-382 6 p.

Research output: Contribution to journalArticle

Calcium Channels
Vasodilator Agents
Rats
Phenylephrine
Vascular Smooth Muscle
2008
26 Citations (Scopus)

Assessment of hypolipidaemic activity of three thiazolidin-4-ones in mice given high-fat diet and fructose

Nampurath, G. K., Mathew, S. P., Khanna, V., Zachariah, R. T., Kanji, S. & Chamallamudi, M. R., 15-02-2008, In : Chemico-Biological Interactions. 171, 3, p. 363-368 6 p.

Research output: Contribution to journalArticle

Niacinamide
High Fat Diet
Nutrition
Hypercholesterolemia
Fructose
4 Citations (Scopus)

In vitro and in vivo hepatoprotective effect of Vitex negundo leaves

Raj, P. V., Chandrasekhar, H. R., Vijayan, P., Dhanaraj, S. A., Rao, C. M., Rao, J. V. & Nitesh, K., 2008, In : Pharmacologyonline. 3, p. 281-295 15 p.

Research output: Contribution to journalArticle

Vitex
Body Weight
Hepatocytes
Hep G2 Cells
Liver
19 Citations (Scopus)

Petroleum ether extract of Cissus quadrangularis (Linn) stimulates the growth of fetal bone during intra uterine developmental period: A morphometric analysis

Potu, B. K., Rao, M. S., Kutty N, G., Bhat, K. M. R., Chamallamudi, M. R. & Nayak, S. R., 2008, In : Clinics. 63, 6, p. 815-820 6 p.

Research output: Contribution to journalArticle

Cissus
Bone Development
Fetal Development
Cartilage
Control Groups
48 Citations (Scopus)

Simultaneous determination of pioglitazone and glimepiride in bulk drug and pharmaceutical dosage form by RP-HPLC method

Karthik, A., Subramanian, G., Mallikarjuna Rao, C., Bhat, K., Ranjithkumar, A., Musmade, P., Surulivelrajan, M., Karthikeyan, K. & Udupa, N., 2008, In : Pakistan Journal of Pharmaceutical Sciences. 21, 4, p. 421-425 5 p.

Research output: Contribution to journalArticle

pioglitazone
glimepiride
Dosage Forms
High Pressure Liquid Chromatography
Pharmaceutical Preparations
7 Citations (Scopus)

The effects of topical (gel) astemizole and terfenadine on wound healing

Srikanth, D., Shenoy, R. & Rao, C., 01-10-2008, In : Indian Journal of Pharmacology. 40, 4, p. 170-174 5 p.

Research output: Contribution to journalArticle

Open Access
Astemizole
Terfenadine
Wound Healing
Gels
Wounds and Injuries