• Madhava Nagar, Manipal. Karnataka State, Pin - 576104.

    India

  • 606 Citations
  • 13 h-Index
20032020

Research output per year

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Research Output

2020

Is viral E6 oncoprotein a viable target? A critical analysis in the context of cervical cancer

Kumar, A., Rathi, E., Hariharapura, R. C. & Kini, S. G., 01-01-2020, (Accepted/In press) In : Medicinal Research Reviews.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Strategic design of dicer substrate siRNA to mitigate the resistance mediated by ABCC1 in doxorubicinresistant breast cancer

Gatta, A. K., Chandrashekhar, R., Udupa, N., Reddy, M. S., Mutalik, S. & Josyula, V. R., 04-2020, In : Indian Journal of Pharmaceutical Sciences. 82, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

2019
3 Citations (Scopus)

Marine microbial metabolites as drug candidates for alzheimer’s disease

Muralidharan, A., Chandrasekhar, R. & Rao, J. V., 12-2019, In : Research Journal of Pharmacy and Technology. 12, 12, p. 6081-6086 6 p.

Research output: Contribution to journalArticle

Novel isatin-indole derivatives as potential inhibitors of chorismate mutase (CM): Their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd-Cu catalysis

Reddy, G. S., Hossain, K. A., Kumar, J. S., Thirupataiah, B., Edwin, R. K., Giliyaru, V. B., Chandrashekhar Hariharapura, R., Shenoy, G. G., Misra, P. & Pal, M., 01-01-2019, In : RSC Advances. 10, 1, p. 289-297 9 p.

Research output: Contribution to journalArticle

Open Access

Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain

Polepalli, S., George, S. M., Valli Sri Vidya, R., Rodrigues, G. S., Ramachandra, L., Chandrashekar, R., M, D. N., Rao, P. P. N., Pestell, R. G. & Rao, M., 01-09-2019, In : International Journal of Biochemistry and Cell Biology. 114, 105558.

Research output: Contribution to journalReview article

2 Citations (Scopus)

siRNA intervention inhibiting viral replication and delivery strategies for treating herpes simplex viral infection

Manda, V., Josyula, V. R. & Hariharapura, R. C., 01-06-2019, In : VirusDisease. 30, 2, p. 180-185 6 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM)

Reddy, G. S., Snehalatha, A. V., Edwin, R. K., Hossain, K. A., Giliyaru, V. B., Hariharapura, R. C., Gautham Shenoy, G., Misra, P. & Pal, M., 01-10-2019, In : Bioorganic Chemistry. 91, 103155.

Research output: Contribution to journalArticle

2018

Exploring the potential of marine microbes in clinical management of Alzheimer's disease: A road map for bioprospecting and identifying promising isolates

Muralidharan, A., Josyula, V. R. & Hariharapura, R. C., 01-09-2018, In : Life Sciences. 208, p. 149-160 12 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Propargylamine (secondary) as a building block in indole synthesis involving ultrasound assisted Pd/Cu-catalyzed coupling-cyclization method: Unexpected formation of (pyrazole)imine derivatives

Sujeevan Reddy, G., Babu Nallapati, S., Sri Saranya, P. S. V. K., Sridhar, B., Bhat Giliyaru, V., Chandrashekhar Hariharapura, R., Gautham Shenoy, G. & Pal, M., 26-12-2018, In : Tetrahedron Letters. 59, 52, p. 4587-4592 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Serum-derived IgG from coxsackievirus A6-infected patients can enhance the infection of peripheral blood mononuclear cells with coxsackievirus A6

Aswathyraj, S., Sane, F., Raghu, C., Sabeena, S., Alidjinou, E. K., Arunkumar, G. & Hober, D., 01-12-2018, In : Microbial Pathogenesis. 125, p. 7-11 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Strategies for improving the specificity of siRNAs for enhanced therapeutic potential

Gatta, A. K., Hariharapura, R. C., Udupa, N., Reddy, M. S. & Josyula, V. R., 03-08-2018, In : Expert Opinion on Drug Discovery. 13, 8, p. 709-725 17 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2017

Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data

Vastrad, B., Vastrad, C., Godavarthi, A. & Chandrashekar, R., 01-11-2017, In : Medical Oncology. 34, 11, 182.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2016

Biosynthesis of copper nanoparticles using copper-resistant Bacillus cereus, a soil isolate

Tiwari, M., Jain, P., Chandrashekhar Hariharapura, R., Narayanan, K., Bhat K., U., Udupa, N. & Rao, J. V., 01-10-2016, In : Process Biochemistry. 51, 10, p. 1348-1356 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

In vitro wound-healing effects of biosynthesized copper nanoparticles

Tiwari, M., Jain, P., Hariharpura, R. C., Udupa, N. & Rao, J. V., 01-02-2016, In : Asian Journal of Pharmaceutical Sciences. 11, 1, p. 158-159 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

A pulse radiolysis study of hyperoside isolated from Hypericum mysorense

Hariharapura, R. C., Mahal, H. S., Srinivasan, R., Jagani, H. & Vijayan, P., 2015, In : Radiation Physics and Chemistry. 107, p. 149-159 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Investigation of the antioxidant and hepatoprotective potential of Hypericum mysorense

Hariharapura, R. C., Srinivasan, R., Ashok, G., Dongre, S. H., Jagani, H. V. & Vijayan, P., 01-09-2014, In : Antioxidants. 3, 3, p. 526-543 18 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2013

A nanoformulation of siRNA and its role in cancer therapy: In vitro and in vivo evaluation

Jagani, H., Rao, J. V., Palanimuthu, V. R., Hariharapura, R. C. & Gang, S., 2013, In : Cellular and Molecular Biology Letters. 18, 1, p. 120-136 17 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Improvement of therapeutic efficacy of PLGA nanoformulation of siRNA targeting anti-apoptotic Bcl-2 through chitosan coating

Jagani, H. V., Josyula, V. R., Palanimuthu, V. R., Hariharapura, R. C. & Gang, S. S., 2013, In : European Journal of Pharmaceutical Sciences. 48, 4-5, p. 611-618 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Profiling of lens protease involved in generation of αA-66-80 crystallin peptide using an internally quenched protease substrate

Hariharapura, R., Santhoshkumar, P. & Krishna Sharma, K., 2013, In : Experimental Eye Research. 109, p. 51-59 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2011

Cytotoxicity, platelet aggregation inhibitory and antioxidant activity of Curcuma amada Roxb. extracts

Policegoudra, R. S., Chandrashekhar, R. H., Aradhya, S. M. & Singh, L., 2011, In : Food Technology and Biotechnology. 49, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

In vitro anticancer activity of microbial isolates from diverse habitats

Treasathomas, A., Venkata Rao, J., Subrahmanyam, V. M., Chandrashekhar, H. R., Maliyakkal, N., Kisan, T. K., Joseph, A. & Udupa, N., 2011, In : Brazilian Journal of Pharmaceutical Sciences. 47, 2, p. 279-287 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nanoformulation of siRNA silencing Bcl-2 gene and its implication in cancer therapy

Jagani, H. V., Josyula, V. R., Hariharapura, R. C., Palanimuthu, V. R. & Gang, S. S. M., 2011, In : Arzneimittel-Forschung/Drug Research. 61, 10, p. 577-586 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010
12 Citations (Scopus)

Hepatoprotective properties of Caesalpinia sappan Linn. heartwood on carbon tetrachloride induced toxicity

Srillakshmi, V. S., Vijayan, P., Raj, P. V., Dhanaraj, S. A. & Chandrashekhar, H. R., 2010, In : Indian Journal of Experimental Biology. 48, 9, p. 905-910 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

In vitro and in vivo hepatoprotective effects of the total alkaloid fraction of Hygrophila auriculata leaves

Raj, V. P., Chandrasekhar, R. H., Vijayan, P., Dhanaraj, S. A., Rao, M. C., Rao, V. J. & Nitesh, K., 01-03-2010, In : Indian Journal of Pharmacology. 42, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
6 Citations (Scopus)

Protective role of catechin on D-galactosamine induced hepatotoxicity through a p53 dependent pathway

Vasanth Raj, P., Nitesh, K., Sagar Gang, S., Hitesh Jagani, V., Raghu Chandrashekhar, H., Venkata Rao, J., Mallikarjuna Rao, C. & Udupa, N., 2010, In : Indian Journal of Clinical Biochemistry. 25, 4, p. 349-356 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Single dose vaccine delivery system of tetanus toxoid formulation based on chitosan microspheres

Dineshkumar, B., Dhanaraj, S. A., Santhi, K., Vijayan, P. & Chandrasekhar, R., 01-12-2010, In : International Journal of Advances in Pharmaceutical Sciences. 1, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2009

Anticancer activity of Hypericum mysorense

Chandrashekhar, R. H., Vasanth Raj, P., Rao, V. J. & Udupa, N., 2009, 2nd International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2009 - Conference Proceedings. 5384082

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Antioxidant activity of Hypericum hookerianum Wight and Arn.

Raghu Chandrashekhar, H., Venkatesh, P., Ponnusankar, S. & Vijayan, P., 2009, In : Natural Product Research. 23, 13, p. 1240-1251 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Estimation of total phenols with special emphasis to antioxidant potentials of few hypericum species

Raghu Chandrashekhar, H., Venkatesh, P., Arumugam, M. & Vijayan, P., 2009, In : Pharmacologyonline. 1, p. 680-687 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mosquito larvicidal activity of Vitex negundo

Vasanth Raj, P., Raghu Chandrasekhar, H., Dhanaraj, S. A., Vijayan, P., Nitesh, K., Subrahmanyam, V. M. & Venkata Rao, J., 2009, In : Pharmacologyonline. 2, p. 975-990 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Screening of plant Macaranga peltata for its antioxidant, antimicrobial and cytotoxicity activity

Verma, M., Raj, P. V., Chandrashekhar, R. H., Rao, J. V. & Udupa, N., 2009, 2nd International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2009 - Conference Proceedings. 5384086

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)
2008

Anti-adipogenic activity of Capsicum annum (Solanaceae) in 3T3 L1

Arumugam, M., Vijayan, P., Raghu, C., Ashok, G., Dhanaraj, S. A. & Kumarappan, C. T., 12-11-2008, In : Journal of Complementary and Integrative Medicine. 5, 1, 28.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Chemoprotective effect of Anogeissus latifolia bark extract on paracetamol-induced hepatotoxicity

Khan, S., Pradeep, H. A., Ashok Kumar, B. S., Anil Kumar, M., Manimaran, S., Chandrasekhar, R. & Vijayan, P., 2008, In : Pharmacologyonline. 2, p. 303-327 25 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

In vitro and in vivo hepatoprotective effect of Vitex negundo leaves

Raj, P. V., Chandrasekhar, H. R., Vijayan, P., Dhanaraj, S. A., Rao, C. M., Rao, J. V. & Nitesh, K., 2008, In : Pharmacologyonline. 3, p. 281-295 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2007

Antitumor activity of the methanol extract of Hypericum hookerianum stem against ehrlich ascites carcinoma in Swiss albino mice

Dongre, S. H., Badami, S., Natesan, S. & Chandrashekhar H., R., 30-04-2007, In : Journal of Pharmacological Sciences. 103, 4, p. 354-359 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Potent in vitro cytotoxic and antioxidant activity of Careya arborea bark extracts

Senthilkumar, N., Badami, S., Cherian, M. M. & Hariharapura, R. C., 01-05-2007, In : Phytotherapy Research. 21, 5, p. 492-495 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Synthesis and cytotoxic activity of novel pyrazoline derivatives against human lung tumor cell line (A549)

Yar, M. S., Siddiqui, A. A., Ali, M. A., Murugan, V. & Chandrashekhar, R., 01-01-2007, In : Journal of the Chinese Chemical Society. 54, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2006

Synthesis of some amino acids incorporated 4(3H)-quinazolinones as possible antiherpes viral agents

Meyyanathan, S. N., Murali, K. E., Chandrashekhar, H. R., Godavarthi, A., Dhanaraj, S. A., Vijayan, P. & Suresh, B., 01-06-2006, In : Indian Drugs. 43, 6, p. 497-502 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2005

In vitro cytotoxic properties of Ipomoea aquatica leaf

Prasad, K. N., Ashok, G., Raghu, C., Shivamurthy, G. R., Vijayan, P. & Aradhya, S. M., 01-11-2005, In : Indian Journal of Pharmacology. 37, 6, p. 397-398 2 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2004

Antiviral activity of medicinal plants of Nilgiris

Vijayan, P., Raghu, C., Ashok, G., Dhanaraj, S. A. & Suresh, B., 01-07-2004, In : Indian Journal of Medical Research. 120, 1, p. 24-29 6 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)

Free radical scavenging activity of selected essential oils

Ashok, G., Raghu, C., Dhanaraj, S. A., Suresh, B. & Vijayan, P., 01-04-2004, In : Indian Drugs. 41, 4, p. 244-245 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The cytotoxic activity of the total alkaloids isolated from different parts of Solanum pseudocapsicum

Vijayan, P., Vijayaraj, P., Setty, P. H. C., Hariharpura, R. C., Godavarthi, A., Badami, S., Arumugam, D. S. & Bhojraj, S., 01-04-2004, In : Biological and Pharmaceutical Bulletin. 27, 4, p. 528-530 3 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2003

In vitro cytotoxic properties of Grewia tiliaefolia bark and lupeol

Badami, S., Vijayan, P., Mathew, N., Chandrashekhar, R., Godavarthi, A., Dhanaraj, S. A. & Suresh, B., 01-08-2003, In : Indian Journal of Pharmacology. 35, 4, p. 250-251 2 p.

Research output: Contribution to journalLetter

13 Citations (Scopus)