• Madhava Nagar, Manipal, Karnataka State. Pin 576104

    India

  • Madhav Nagar, MCOPS Building

    576104 Manipal

    India

  • 2551 Citations
  • 27 h-Index
20012020

Research output per year

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Research Output

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Article
2020

Antidiabetic drug metformin affects the developmental competence of cleavage-stage embryos

Nayak, G., Salian, S. R., Agarwal, P., Suresh Poojary, P., Rao, A., Kumari, S., Kalthur, S. G., Shreya, A. B., Mutalik, S., Adiga, S. K. & Kalthur, G., 01-01-2020, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journalArticle

Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress

Hegde, S., Poojary, K. K., Rasquinha, R., Crasta, D. N., Gopalan, D., Mutalik, S., Siddiqui, S., Adiga, S. K. & Kalthur, G., 01-01-2020, (Accepted/In press) In : Pesticide Biochemistry and Physiology. 104588.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hyaluronic acid-drug conjugate modified core-shell MOFs as pH responsive nanoplatform for multimodal therapy of glioblastoma

Pandey, A., Kulkarni, S., Vincent, A. P., Nannuri, S. H., George, S. D. & Mutalik, S., 15-10-2020, In : International Journal of Pharmaceutics. 588, 119735.

Research output: Contribution to journalArticle

Naringin nano-ethosomal novel sunscreen creams: Development and performance evaluation

Gollavilli, H., Hegde, A. R., Managuli, R. S., Bhaskar, K. V., Dengale, S. J., Reddy, M. S., Kalthur, G. & Mutalik, S., 09-2020, In : Colloids and Surfaces B: Biointerfaces. 193, 111122.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pediatric dosage forms-challenges and recent developments: A critical review

Galande, A. D., Khurana, N. A. & Mutalik, S., 01-07-2020, In : Journal of Applied Pharmaceutical Science. 10, 7, p. 155-166 12 p.

Research output: Contribution to journalArticle

Open Access

Strategic design of dicer substrate siRNA to mitigate the resistance mediated by ABCC1 in doxorubicinresistant breast cancer

Gatta, A. K., Chandrashekhar, R., Udupa, N., Reddy, M. S., Mutalik, S. & Josyula, V. R., 04-2020, In : Indian Journal of Pharmaceutical Sciences. 82, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

Surface engineered nanoliposomal platform for selective lymphatic uptake of asenapine maleate: In vitro and in vivo studies

Managuli, R. S., Wang, J. T. W., Faruqu, F. M., Pandey, A., Jain, S., Al-Jamal, K. T. & Mutalik, S., 04-2020, In : Materials Science and Engineering C. 109, 110620.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2 Citations (Scopus)
2019

Application of hot melt extrusion for the solubility enhancement of a BCS class II drug

Kumar, A. M. S., Kulyadi, G. P., Mutalik, S., Kulkarni, V. I. & Tippavajhala, V. K., 08-2019, In : Research Journal of Pharmacy and Technology. 12, 8, p. 3751-3754 4 p.

Research output: Contribution to journalArticle

Asenapine maleate-loaded nanostructured lipid carriers: Optimization and in vitro, ex vivo and in vivo evaluations

Managuli, R. S., Wang, J. T., Faruqu, F. N., Kushwah, V., Raut, S. Y., Shreya, A. B., Al-Jamal, K. T., Jain, S. & Mutalik, S., 01-04-2019, In : Nanomedicine. 14, 7, p. 889-910 22 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
3 Citations (Scopus)

Challenges in the development of analytical test procedure for aminoglycosides: A critical review

Hari, R., Taherunnisa, S., Raut, S. Y., Mutalik, S. & Koteshwara, K. B., 01-01-2019, In : Journal of Applied Pharmaceutical Science. 9, 11, p. 145-152 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Cyclodextrins as Carriers in Targeted Delivery of Therapeutic Agents: Focused Review on Traditional and Inimitable Applications

Raut, S. Y., Manne, A. S. N., Kalthur, G., Jain, S. & Mutalik, S., 01-01-2019, In : Current Pharmaceutical Design. 25, 4, p. 444-454 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
7 Citations (Scopus)

Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo evaluation

Boppana, R., Yadaorao Raut, S., Krishna Mohan, G., Sa, B., Mutalik, S., Reddy, K. R., Das, K. K., Biradar, M. S. & Kulkarni, R. V., 01-08-2019, In : Colloids and Surfaces B: Biointerfaces. 180, p. 362-370 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
4 Citations (Scopus)

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Emerging Lipid Based Drug Delivery Systems

Shirodkar, R. K., Kumar, L., Mutalik, S. & Lewis, S., 01-08-2019, In : Pharmaceutical Chemistry Journal. 53, 5, p. 440-453 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018
2 Citations (Scopus)

Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In : International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Skin permeation of gemcitabine hydrochloride by passive diffusion, iontophoresis and sonophoresis: In vitro and in vivo evaluations

Baji, S., Hegde, A. R., Kulkarni, M., Raut, S. Y., Manikkath, J., Reddy, M. S. & Mutalik, S., 01-10-2018, In : Journal of Drug Delivery Science and Technology. 47, p. 49-54 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2017

A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: Tumor-specific homing directed by nestin

Prabhu, S., Goda, J. S., Mutalik, S., Mohanty, B. S., Chaudhari, P., Rai, S., Udupa, N. & Rao, B. S. S., 14-08-2017, In : Nanoscale. 9, 30, p. 10919-10932 14 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Bioactive PLGA–curcumin microparticle-embedded chitosan scaffold: in vitro and in vivo evaluation

Amirthalingam, M., Kasinathan, N., Amuthan, A., Mutalik, S., Sreenivasa Reddy, M. & Nayanabhirama, U., 17-02-2017, In : Artificial Cells, Nanomedicine and Biotechnology. 45, 2, p. 233-241 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Characterization of the Phenolic Compound, Gallic Acid from Sansevieria roxburghiana Schult and Schult. f. Rhizomes and Antioxidant and Cytotoxic Activities Evaluation

Maheshwari, R., Shreedhara, C. S., Polu, P. R., Managuli, R. S., Xavier, S. K., Lobo, R., Setty, M. & Mutalik, S., 11-10-2017, In : Pharmacognosy Magazine. 13, 51, p. S693-S699

Research output: Contribution to journalArticle

1 Citation (Scopus)
5 Citations (Scopus)
2 Citations (Scopus)
6 Citations (Scopus)

Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen

Manikkath, J., Hegde, A. R., Kalthur, G., Parekh, H. S. & Mutalik, S., 15-04-2017, In : International Journal of Pharmaceutics. 521, 1-2, p. 110-119 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2 Citations (Scopus)

Low frequency ultrasound and PAMAM dendrimer facilitated transdermal delivery of ketoprofen

Manikkath, J., Manikkath, A., Shavi, G. V., Bhat, K. & Mutalik, S., 01-10-2017, In : Journal of Drug Delivery Science and Technology. 41, p. 334-343 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
20 Citations (Scopus)

Preclinical pharmacokinetics and biodistribution studies of asenapine maleate using novel and sensitive RP-HPLC method

Managuli, R. S., Gourishetti, K., Shenoy, R. R., Koteshwara, K. B., Reddy, M. S. & Mutalik, S., 01-07-2017, In : Bioanalysis. 9, 14, p. 1037-1047 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Skin Delivery of EGCG and Silibinin: Potential of Peptide Dendrimers for Enhanced Skin Permeation and Deposition

Shetty, P. K., Manikkath, J., Tupally, K., Kokil, G., Hegde, A. R., Raut, S. Y., Parekh, H. S. & Mutalik, S., 01-08-2017, In : AAPS PharmSciTech. 18, 6, p. 2346-2357 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 28-11-2017, (Accepted/In press) In : Zygote. p. 1-14 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2016

Aeromonas hydrophila OmpW PLGA nanoparticle oral vaccine shows a dose-dependent protective immunity in rohu (Labeo rohita)

Dubey, S., Avadhani, K., Mutalik, S., Sivadasan, S. M., Maiti, B., Paul, J., Girisha, S. K., Venugopal, M. N., Mutoloki, S., Evensen, Ø., Karunasagar, I. & Munang’andu, H. M., 01-06-2016, In : Vaccines. 4, 2, 21.

Research output: Contribution to journalArticle

21 Citations (Scopus)

A novel nanoproliposomes of lercanidipine: Development, in vitro and preclinical studies to support its effectiveness in hypertension therapy

Deshpande, P. B., Gurram, A. K., Deshpande, A., Shavi, G. V., Musmade, P., Arumugam, K., Averineni, R. K., Mutalik, S., Reddy, M. S. & Udupa, N., 01-10-2016, In : Life Sciences. 162, p. 125-137 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Determination of antibacterial and antifungal properties of rose extract- An in vitro study

Bahl, D., Karande, S., Chakravarthy, A., Mutalik, S. & Devkar, R., 2016, In : International Journal of Pharmacognosy and Phytochemical Research. 8, 10, p. 1695-1697 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

Mutalik, S., Suthar, N. A., Managuli, R. S., Shetty, P. K., Avadhani, K., Kalthur, G., Kulkarni, R. V. & Thomas, R., 01-05-2016, In : International Journal of Biological Macromolecules. 86, p. 709-720 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Development and validation of a reverse phase HPLC method for the estimation of lacidipine in rat plasma: Application to preclinical pharmacokinetics

Shirodkar, R. K., Kumar, L., Misra, C., Managuli, R., Attari, Z., Mutalik, S. & Lewis, S. A., 2016, In : Latin American Journal of Pharmacy. 35, 1, p. 124-129 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
13 Citations (Scopus)

Development and validation of RP-HPLC method for estimation of epigallocatechin -3-gallate (EGCG) in lipid based nanoformulations

Avadhani, K. S., Amirthalingam, M., Reddy, M. S., Udupa, N. & Mutalik, S., 2016, In : Research Journal of Pharmacy and Technology. 9, 6, p. 725-730 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
24 Citations (Scopus)

Edwardsiella tarda OmpA encapsulated in chitosan nanoparticles shows superior protection over inactivated whole cell vaccine in orally vaccinated fringed-lipped peninsula carp (Labeo fimbriatus)

Dubey, S., Avadhani, K., Mutalik, S., Sivadasan, S. M., Maiti, B., Girisha, S. K., Venugopal, M. N., Mutoloki, S., Evensen, Ø., Karunasagar, I. & Munang’andu, H. M., 01-12-2016, In : Vaccines. 4, 4, 40.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Ethambutol induces testicular damage and decreases the sperm functional competence in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Prabhu, A. D., Khandige, N., Kalthur, S. G., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Environmental Toxicology and Pharmacology. 47, p. 28-37 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Ethanolic extract of Moringa oleifera Lam. leaves protect the pre-pubertal spermatogonial cells from cyclophosphamide-induced damage

Nayak, G., Honguntikar, S. D., Kalthur, S. G., D'Souza, A. S., Mutalik, S., Setty, M. M., Kalyankumar, R., Krishnamurthy, H., Kalthur, G. & Adiga, S. K., 22-04-2016, In : Journal of Ethnopharmacology. 182, p. 101-109 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)