3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione

Hemmige S. Yathirajan, Kuriya M. Lokanatha Rai, Santhosh L. Gaonkar, Rajenahally S. Narasegowda, Basappa Prabhuswamy, Michael Bolte

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The structural properties of C10H8N2O 4S compound were studied. The compound was investigated as a PPAR-γ-agonist that leads to the development of several insulin-sensitizing drugs for the treatment of diabetes. The compound serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. It was observed that the planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring in the compound, which describes its crystal structure.

Original languageEnglish
JournalActa Crystallographica Section E: Structure Reports Online
Volume61
Issue number2
DOIs
Publication statusPublished - 02-2005

Fingerprint

Insulin
Dione
Medical problems
Drug products
Structural properties
Crystal structure
sensitizing
insulin
Peroxisome Proliferator-Activated Receptors
rings
Hypoglycemic Agents
Pharmaceutical Preparations
drugs
crystal structure
synthesis
thiazolidine-2,4-dione

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Yathirajan, H. S., Lokanatha Rai, K. M., Gaonkar, S. L., Narasegowda, R. S., Prabhuswamy, B., & Bolte, M. (2005). 3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione. Acta Crystallographica Section E: Structure Reports Online, 61(2). https://doi.org/10.1107/S1600536804033951
Yathirajan, Hemmige S. ; Lokanatha Rai, Kuriya M. ; Gaonkar, Santhosh L. ; Narasegowda, Rajenahally S. ; Prabhuswamy, Basappa ; Bolte, Michael. / 3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione. In: Acta Crystallographica Section E: Structure Reports Online. 2005 ; Vol. 61, No. 2.
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Yathirajan, HS, Lokanatha Rai, KM, Gaonkar, SL, Narasegowda, RS, Prabhuswamy, B & Bolte, M 2005, '3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione', Acta Crystallographica Section E: Structure Reports Online, vol. 61, no. 2. https://doi.org/10.1107/S1600536804033951

3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione. / Yathirajan, Hemmige S.; Lokanatha Rai, Kuriya M.; Gaonkar, Santhosh L.; Narasegowda, Rajenahally S.; Prabhuswamy, Basappa; Bolte, Michael.

In: Acta Crystallographica Section E: Structure Reports Online, Vol. 61, No. 2, 02.2005.

Research output: Contribution to journalArticle

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AU - Yathirajan, Hemmige S.

AU - Lokanatha Rai, Kuriya M.

AU - Gaonkar, Santhosh L.

AU - Narasegowda, Rajenahally S.

AU - Prabhuswamy, Basappa

AU - Bolte, Michael

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