Find Research Outputs

Search concepts
Selected filters
2015
31 Citations (Scopus)
Simvastatin
Frontal Lobe
Aluminum
Hippocampus
Rivastigmine
2018
14 Citations (Scopus)

Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In : Cytotechnology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Episodic Memory
Catechin
Memory Disorders
Cytotoxicity
Doxorubicin
2016
3 Citations (Scopus)

Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In : Andrologia. 48, 10, p. 1236-1243 8 p.

Research output: Contribution to journalArticle

Aphrodisiacs
Wistar Rats
Oligospermia
Glass
Safety
2017
10 Citations (Scopus)
Chalcone
chalcone
Cell Cycle Checkpoints
colorectal neoplasms
Colonic Neoplasms
2018
1 Citation (Scopus)

Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In : European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

Research output: Contribution to journalArticle

Interleukin-6
Lipopolysaccharides
Prostaglandin-Endoperoxide Synthases
Reactive Oxygen Species
Tarsal Joints
2016
11 Citations (Scopus)
Pharmacists
Chronic Obstructive Pulmonary Disease
Quality of Life
India
Lung
4 Citations (Scopus)

Selected novel 5’-amino-2’-hydroxy-1, 3-diaryl-2- propen-1-ones arrest cell cycle of HCT-116 in G0/G1 phase

Simon, L., Srinivasan, K. K., Kumar, N., Reddy, N. D., Biswas, S., Mallikarjuna Rao, C. & Moorkoth, S., 13-01-2016, In : EXCLI Journal. 15, p. 21-32 12 p.

Research output: Contribution to journalArticle

HCT116 Cells
Cell Cycle Resting Phase
G1 Phase
Cell Cycle Checkpoints
interphase
2 Citations (Scopus)
Arthritis
Experimental Arthritis
Cytokines
Dinoprostone
Stomach
Aluminum
Curcumin
Aptitude
Water
Neurodegenerative Diseases
2015
8 Citations (Scopus)

The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
Epithelial Cells
Methylene Chloride
Apoptosis
Neoplasms
2014
29 Citations (Scopus)

Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

Nampoothiri, M., Reddy, N. D., John, J., Kumar, N., Kutty Nampurath, G. & Rao Chamallamudi, M., 2014, In : Behavioural Neurology. 2014, 674164.

Research output: Contribution to journalArticle

Glutamic Acid
Insulin
Reactive Oxygen Species
Acridine Orange
Ethidium
2013
20 Citations (Scopus)

Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In : Lipids. 48, 6, p. 633-638 6 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Triglycerides
Cholesterol
Plasmas
Nutrition
2011
8 Citations (Scopus)
Rivastigmine
Pharmacokinetics
Fluorescence
Brain
Liquid-Liquid Extraction
2018
3 Citations (Scopus)

Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model

Gill, M., Kinra, M., Rai, A., Chamallamudi, M. R. & Kumar, N., 01-01-2018, In : NeuroReport. 29, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Antioxidants
Sucrose
Brain
Plant Bark
4 Citations (Scopus)

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 08-01-2018, (Accepted/In press) In : Toxicology Mechanisms and Methods. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptor Antagonists
Neurokinin-1 Receptors
Memory Disorders
Aluminum
Tryptophan
2013
18 Citations (Scopus)
Catechin
Caspases
Hep G2 Cells
Liposomes
Biological Availability
2018
1 Citation (Scopus)

Naringin ameliorates doxorubicin-induced neurotoxicity in vitro and cognitive dysfunction in vivo

Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Mallik, S. B., Gourishetti, K., Hussain, S. M., Rao, C. M. & Nandakumar, K., 01-04-2018, In : Pharmacognosy Magazine. 14, 55, p. S197-S207

Research output: Contribution to journalArticle

Doxorubicin
Episodic Memory
Locomotion
Reactive Oxygen Species
Flow Cytometry
2016
3 Citations (Scopus)

Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In : Cytotechnology. 68, 6, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

Amikacin
Cytotoxicity
Tumors
Cells
Derivatives
2011
27 Citations (Scopus)

Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats

Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 27-01-2011, In : Journal of Ethnopharmacology. 133, 2, p. 608-612 5 p.

Research output: Contribution to journalArticle

Sesamum
Wound Healing
Dexamethasone
Protein-Lysine 6-Oxidase
Wounds and Injuries
2015
7 Citations (Scopus)

Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In : Pharmacognosy Magazine. 11, 44, p. S296-S302

Research output: Contribution to journalArticle

Curcumin
Inflammatory Bowel Diseases
Interleukin-6
Tumor Necrosis Factor-alpha
Curcuma
2013
10 Citations (Scopus)

Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In : Pharmacological Reports. 65, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

Dinitrochlorobenzene
Sesamum
Sulfasalazine
Nitrites
Inflammatory Bowel Diseases
2016
2 Citations (Scopus)
2019
1 Citation (Scopus)

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In : Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journalArticle

Metformin
Lipopolysaccharides
Down-Regulation
Illness Behavior
Oxidative Stress

Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2019, (Accepted/In press) In : Journal of Functional Foods. 103638.

Research output: Contribution to journalArticle

Illness Behavior
Coffee
anxiety
caffeic acid
caffeine
2010
20 Citations (Scopus)

Anti-osteoporotic activity of the petroleum ether extract of Cissus quadrangularis Linn. in ovariectomized wistar rats

Potu, B. K., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Nayak, S. R. & Thomas, H., 2010, In : Chang Gung Medical Journal. 33, 3, p. 252-257 6 p.

Research output: Contribution to journalArticle

Cissus
Ovariectomy
Wistar Rats
Femur
Therapeutics
2012
5 Citations (Scopus)

Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In : Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

Xanthium
Chloroform
Hexanes
Mortality
Body Weight
4 Citations (Scopus)

Histological and physiochemical standardization of Melia azedarach. Linn bark

Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In : Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

Research output: Contribution to journalArticle

Melia azedarach
Sieves
Standardization
Phloem
Phytochemicals
2011
16 Citations (Scopus)

Development and validation of a HPLC method for quantification of rivastigmine in rat urine and identification of a novel metabolite in urine by LC-MS/MS

Arumugam, K., Chamallamudi, M. R., Gilibili, R. R., Mullangi, R., Ganesan, S., Kar, S. S., Averineni, R., Shavi, G. & Udupa, N., 03-2011, In : Biomedical Chromatography. 25, 3, p. 353-361 9 p.

Research output: Contribution to journalArticle

Rivastigmine
Metabolites
Rats
High Pressure Liquid Chromatography
Urine
temozolomide
High Pressure Liquid Chromatography
Brain
formic acid
Pharmaceutical Preparations
2014
8 Citations (Scopus)

Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In : The Scientific World Journal. 2014, 673248.

Research output: Contribution to journalArticle

Acetic Acid
acetic acid
Peroxidase
nitrite
Rats
2017
67 Citations (Scopus)

Epigenetics in cancer: Fundamentals and Beyond

Biswas, S. & Rao, C. M., 01-05-2017, In : Pharmacology and Therapeutics. 173, p. 118-134 17 p.

Research output: Contribution to journalReview article

Epigenomics
Neoplasms
Carcinogenesis
Histone Code
Gene Targeting
2018
22 Citations (Scopus)

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

Biswas, S. & Rao, C. M., 15-10-2018, In : European Journal of Pharmacology. 837, p. 8-24 17 p.

Research output: Contribution to journalReview article

Epigenomics
Neoplasms
Enzymes
Therapeutics
Chromatin
2013
14 Citations (Scopus)

In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In : Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Cisplatin
Neoplasms
Tumors
Bearings (structural)
2011
18 Citations (Scopus)

Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In : Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

Research output: Contribution to journalArticle

Quinoxalines
Anti-Inflammatory Agents
Antioxidants
Derivatives
Ricinoleic Acids
2016
7 Citations (Scopus)

Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride

Jetti, R., Raghuveer, C. & Rao, M. C., 2016, In : Toxicology and Industrial Health. 32, 1, p. 183-187 5 p.

Research output: Contribution to journalArticle

Ginkgo biloba
Memory Disorders
Fluorides
Ascorbic Acid
Learning
10 Citations (Scopus)

An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

Reddy, N. D., Shoja, M. H., Biswas, S., Nayak, P. G., Kumar, N. & Rao, C. M., 25-06-2016, In : Chemico-Biological Interactions. 253, p. 112-124 13 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Sulfonamides
Human Activities
Cells
Histone Deacetylases
2015
18 Citations (Scopus)

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In : Chemico-Biological Interactions. 233, p. 81-94 14 p.

Research output: Contribution to journalArticle

Sulfonamides
Caspase 7
Colon
Adenocarcinoma
Annexin A5
22 Citations (Scopus)

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In : Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

Research output: Contribution to journalArticle

Lipids
Frontal Lobe
Hippocampus
Sesame Oil
Rivastigmine
2014
10 Citations (Scopus)

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In : Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Carrageenan
Cytokines
Inflammation
Dinoprostone
Rats
2016
3 Citations (Scopus)

In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer

Shoja, M. H., Reddy, N. D., Nayak, P. G., Biswas, S., Srinivasan, K. K. & Rao, C. M., 20-06-2016, In : Journal of Ethnopharmacology. 186, p. 159-168 10 p.

Research output: Contribution to journalArticle

Rutaceae
9,10-Dimethyl-1,2-benzanthracene
Breast Neoplasms
Matrix Metalloproteinases
Sprague Dawley Rats
2018
1 Citation (Scopus)

Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 07-03-2018, (Accepted/In press) In : Metabolic Brain Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

Purinergic P1 Receptor Antagonists
Cyclooxygenase Inhibitors
Haloperidol
Antipsychotic Agents
Caffeine
1 Citation (Scopus)

Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In : Andrologia. 50, 7, e13037.

Research output: Contribution to journalArticle

Wistar Rats
Sexual Behavior
Spermatozoa
Aphrodisiacs
Sperm Count
2010
19 Citations (Scopus)

In vitro and in vivo hepatoprotective effects of the total alkaloid fraction of Hygrophila auriculata leaves

Raj, V. P., Chandrasekhar, R. H., Vijayan, P., Dhanaraj, S. A., Rao, M. C., Rao, V. J. & Nitesh, K., 01-03-2010, In : Indian Journal of Pharmacology. 42, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

Acanthaceae
Alkaloids
Hep G2 Cells
Hepatocytes
Body Weight
25 Citations (Scopus)

Antitumor and antioxidant activity of Polyalthia longifolia stem bark ethanol extract

Manjula, S. N., Kenganora, M., Parihar, V. K., Kumar, S., Nayak, P. G., Kumar, N., Ranganath Pai, K. S. & Rao, C. M., 2010, In : Pharmaceutical Biology. 48, 6, p. 690-696 7 p.

Research output: Contribution to journalArticle

Polyalthia
Ascites
Ethanol
Antioxidants
Inhibitory Concentration 50
12 Citations (Scopus)
Silymarin
Galactosamine
Lecithins
Toxicity
Rats
19 Citations (Scopus)

Protective role of catechin on D-galactosamine induced hepatotoxicity through a p53 dependent pathway

Vasanth Raj, P., Nitesh, K., Sagar Gang, S., Hitesh Jagani, V., Raghu Chandrashekhar, H., Venkata Rao, J., Mallikarjuna Rao, C. & Udupa, N., 2010, In : Indian Journal of Clinical Biochemistry. 25, 4, p. 349-356 8 p.

Research output: Contribution to journalArticle

Galactosamine
Catechin
Liver
Mitochondrial Membrane Potential
Enzyme activity
2014
5 Citations (Scopus)

Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In : The Scientific World Journal. 2014, 430734.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In : BioMed Research International. 2014, 569130.

Research output: Contribution to journalArticle

Dimenhydrinate
Aberrant Crypt Foci
1,2-Dimethylhydrazine
Colonic Neoplasms
Cells
2019

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In : Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journalArticle

Silymarin
Liposomes
Wistar Rats
Alcohols
Biological Availability