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• 2019

  Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

  Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In: Psychopharmacology. 236, 6, p. 1829-1838 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Illness Behavior
  • Cannabinoid Receptors
  • Lipopolysaccharides
  • Oxidative Stress
  • Tumor Necrosis Factor-alpha
  10 Citations (Scopus)

• Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In: Biomedical Reports. 11, 2, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Sprague Dawley Rats
  • Oxidative Stress
  7 Citations (Scopus)

• Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

  Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In: Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptors
  • Nervous System Diseases
  • Substance P
  • Neurokinin-1 Receptor Antagonists
  • Drug Industry

• Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

  Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In: Pharmacology. 103, 5-6, p. 315-319 5 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Acute Kidney Injury
  • Reperfusion
  • Ischemia
  • Celecoxib
  4 Citations (Scopus)

• Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

  Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In: Pharmacological Reports. 71, 4, p. 703-712 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Silymarin
  • Liposomes
  • Wistar Rats
  • Alcohols
  • In Vitro Techniques
  1 Citation (Scopus)

• Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

  Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In: Experimental Gerontology. 125, 1 p.

  Research output: Contribution to journal › Article › peer-review

  • N-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-N,N',N',N'',N''-pentaacetic acid
  • Muscle
  • Locomotion
  • Pharmacology
  • Sarcopenia

• Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

  Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In: Inflammopharmacology. 27, 5, p. 941-948 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipopolysaccharides
  • Down-Regulation
  • Illness Behavior
  • Oxidative Stress
  • Anti-Inflammatory Agents
  8 Citations (Scopus)

• Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

  Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In: Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylnitrosourea
  • Rutin
  • Rats
  • Doxorubicin
  • Cognitive Dysfunction
  3 Citations (Scopus)
• 2017

  Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

  Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In: NeuroReport. 28, 9, p. 540-544 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Memory
  • Dementia
  • Insulin
  • Glucose
  12 Citations (Scopus)

• Epigenetics in cancer: Fundamentals and Beyond

  Biswas, S. & Rao, C. M., 01-05-2017, In: Pharmacology and Therapeutics. 173, p. 118-134 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Neoplasms
  • Carcinogenesis
  • Nucleosomes
  • Gene Targeting
  88 Citations (Scopus)

• Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

  Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon tetrachloride
  • Liver
  • Toxicity
  • Carbon
  • Carbon Tetrachloride
  1 Citation (Scopus)

• Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

  Wankhede, S., Kumar, N., Simon, L., Biswas, S., Gourishetti, K., Ramalingayya, G. V., Joshi, M. & Rao, C. M., 19-10-2017, In: EXCLI Journal. 16, p. 1150-1163 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcones
  • chalcones
  • breast neoplasms
  • Tumor Burden
  • neoplasms

• Insulin Combined with Glucose Improves Spatial Learning and Memory in Aluminum Chloride-Induced Dementia in Rats

  Nampoothiri, M., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-01-2017, In: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 36, 2, p. 159-169 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Learning
  • Rats
  • Spatial Memory
  • Dementia
  4 Citations (Scopus)

• In vitro and in vivo anticancer studies of 2′-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by hdac inhibition and cell cycle arrest

  Pande, A. N., Biswas, S., Reddy, N. D., Jayashree, B. S., Kumar, N. & Rao, C. M., 03-04-2017, In: EXCLI Journal. 16, p. 448-463 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcone
  • chalcone
  • cell cycle checkpoints
  • colorectal neoplasms
  • Cell Cycle Checkpoints
  14 Citations (Scopus)

• Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

  Ramalingayya, G. V., Cheruku, S. P., Nayak, P. G., Kishore, A., Shenoy, R., Rao, M. & Krishnadas, N., 29-03-2017, In: Drug Design, Development and Therapy. 11, p. 1011-1026 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutin
  • Memory Disorders
  • Doxorubicin
  • Wistar Rats
  • In Vitro Techniques
  26 Citations (Scopus)

• Temozolomide and its stability—a critical factor

  Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • Drugs
  • drug
  • Degradation
  • Pharmaceutical Preparations
  2 Citations (Scopus)
• 2015

  Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

  Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In: Pharmacognosy Magazine. 11, 44, p. S296-S302

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Curcumin
  • Inflammatory Bowel Diseases
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  11 Citations (Scopus)

• Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

  Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In: International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Sun hoods
  • Radiation protection
  • Antioxidants
  • Radiation Protection
  40 Citations (Scopus)

• Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In: Journal of Ethnopharmacology. 168, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Cell Cycle Checkpoints
  • Caspase 3
  • Breast Neoplasms
  • lupeol
  20 Citations (Scopus)

• In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

  Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In: Chemico-Biological Interactions. 233, p. 81-94 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Cells
  • Enzyme inhibition
  • Derivatives
  • Colon
  20 Citations (Scopus)

• Modulatory role of simvastatin against aluminium chloride-induced behavioural and biochemical changes in rats

  Nampoothiri, M., John, J., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 2015, In: Behavioural Neurology. 2015, 210169.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Simvastatin
  • Aluminum
  • Frontal Lobe
  • Hippocampus
  46 Citations (Scopus)

• Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

  John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Aluminum Chloride
  • Lipids
  • Frontal Lobe
  • Hippocampus
  26 Citations (Scopus)

• Targets in anticancer research-a review

  Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In: Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmaceutical Preparations
  • Clinical Trials
  • Aromatase
  • Histone Deacetylases
  • Cyclin-Dependent Kinases
  12 Citations (Scopus)

• The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  • Neoplasms
  12 Citations (Scopus)
• 2014

  Curriculum for pharmacology in pharmacy institutions in India: Opportunities and challenges

  Goyal, R. K., Bhise, S. B., Srinivasan, B. P., Rao, C. M., Sen, T. & Koneri, R., 2014, In: Indian Journal of Pharmacology. 46, 3, p. 241-245 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Molecular Farming
  • Pharmacy
  • Curriculum
  • India
  • Pharmacology
  3 Citations (Scopus)

• Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 430734.

  Research output: Contribution to journal › Comment/debate › peer-review
  5 Citations (Scopus)

• Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

  Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In: BioMed Research International. 2014, 569130.

  Research output: Contribution to journal › Article › peer-review

  • Dimenhydrinate
  • Aberrant Crypt Foci
  • 1,2-Dimethylhydrazine
  • Colonic Neoplasms
  • N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
  7 Citations (Scopus)

• Influence of milk components in establishing biofilm mediated bacterial mastitis infections in cattle: A fractional factorial approach

  Atulya, M., Jesil Mathew, A., Venkata Rao, J. & Mallikarjuna Rao, C., 02-2014, In: Research in Veterinary Science. 96, 1, p. 25-27 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Mastitis
  • milk composition
  • biofilm
  • mastitis
  • Biofilms
  12 Citations (Scopus)

• Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

  Nampoothiri, M., Reddy, N. D., John, J., Kumar, N., Kutty Nampurath, G. & Rao Chamallamudi, M., 2014, In: Behavioural Neurology. 2014, 674164.

  Research output: Contribution to journal › Article › peer-review

  • Glutamic Acid
  • Insulin
  • Reactive Oxygen Species
  • Acridine Orange
  • Ethidium
  33 Citations (Scopus)

• Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 673248.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Rats
  • Acetic Acid
  • acetic acid
  • Peroxidase
  8 Citations (Scopus)

• Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

  Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In: Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Tumors
  • Derivatives
  • Liquids
  • Cytotoxicity
  18 Citations (Scopus)

• Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

  Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In: Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Carrageenan
  • Rats
  • Dinoprostone
  • Cytokines
  • Inflammation
  10 Citations (Scopus)

• Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

  Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In: Pharmacological Reports. 66, 5, p. 788-798 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Silybin
  • Silymarin
  • Liposomes
  • Biological Availability
  • Hepatocytes
  59 Citations (Scopus)

• Synthesis, characterization, and preclinical evaluation of new thiazolidin-4-ones substituted with p-chlorophenoxy acetic acid and clofibric acid against insulin resistance and metabolic disorder

  Gowdra, V. S., Mudgal, J., Bansal, P., Nayak, P. G., Manohara Reddy, S. A., Shenoy, G. G., Valiathan, M., Chamallamudi, M. R. & Nampurath, G. K., 2014, In: BioMed Research International. 2014, 620434.

  Research output: Contribution to journal › Article › peer-review

  • Clofibric Acid
  • Acetic Acid
  • Insulin Resistance
  • Hypoadiponectinemia
  • Medical problems
  4 Citations (Scopus)

• The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In: Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vernonia
  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  7 Citations (Scopus)
• 2012

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)

• Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)

• Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)

• Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)