Find Research outputs — Manipal Academy of Higher Education, Manipal, India

2017

In vitro and in vivo anticancer studies of 2′-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by hdac inhibition and cell cycle arrest

Pande, A. N., Biswas, S., Reddy, N. D., Jayashree, B. S., Kumar, N. & Rao, C. M., 03-04-2017, In: EXCLI Journal. 16, p. 448-463 16 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2016

Validation of a sensitive and robust reversed phase-HPLC method for determination of temozolomide

Attari, Z., Kumar, L., Rao, C. M. & Koteshwara, K. B., 2016, In: Latin American Journal of Pharmacy. 35, 5, p. 967-971 5 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

2012

Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

2014

Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In: Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2020

Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In: 3 Biotech. 10, 4, 149.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2012

Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

2013

In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In: Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2019

Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In: Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

Research output: Contribution to journal › Article › peer-review

2011

Effect of Dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats

Rao, M. C., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, G. N. & Shenoy, R. R., 09-2011, In: Molecular and Cellular Biochemistry. 355, 1-2, p. 249-256 8 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

2014

Curriculum for pharmacology in pharmacy institutions in India: Opportunities and challenges

Goyal, R. K., Bhise, S. B., Srinivasan, B. P., Rao, C. M., Sen, T. & Koneri, R., 2014, In: Indian Journal of Pharmacology. 46, 3, p. 241-245 5 p.

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

2017

Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In: NeuroReport. 28, 9, p. 540-544 5 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

2015

Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In: Pharmacognosy Magazine. 11, 44, p. S296-S302

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

2014

Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 673248.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

2013

A study on the role of (+)-catechin in suppression of HepG2 proliferation via caspase dependent pathway and enhancement of its in vitro and in vivo cytotoxic potential through liposomal formulation

Jain, P., Kumar, N., Josyula, V. R., Jagani, H. V., Udupa, N., Mallikarjuna Rao, C. & Vasanth Raj, P., 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 353-365 13 p.

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

2011

High performance liquid chromatographic fluorescence detection method for the quantification of rivastigmine in rat plasma and brain: Application to preclinical pharmacokinetic studies in rats

Arumugam, K., Chamallamudi, M. R., Mallayasamy, S. R., Mullangi, R., Ganesan, S., Jamadar, L., Ranjithkumar, A. & Udupa, N., 2011, In: Journal of Young Pharmacists. 3, 4, p. 315-321 7 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2016

Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In: Cytotechnology. 68, 6, p. 2553-2565 13 p.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

2014

Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 430734.

Research output: Contribution to journal › Comment/debate › peer-review

5 Citations (Scopus)

2020

Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 01-11-2020, In: Andrologia.

Research output: Contribution to journal › Article › peer-review

2016

Role of the drug transporter ABCC3 in breast cancer chemoresistance

Balaji, S. A., Udupa, N., Chamallamudi, M. R., Gupta, V. & Rangarajan, A., 01-05-2016, In: PLoS One. 11, 5, e0155013.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

2013

Impact of caffeic acid on aluminium chloride-induced dementia in rats

Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In: Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

2020

Evaluation of hepatoprotective effect of a polyherbal megakutki against paracetamol-induced hepatotoxicity

Elizabeth Giri, A., Rao, V., Singhal, S., Gourishetti, K., Biswas, S., Nandakumar, K., Chamllamudi, M. R., Dave, J., Dave, R., Sumalatha, S. & Kumar, N., 01-10-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 4, p. 1080-1088 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2013

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In: American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2016

Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In: Andrologia. 48, 10, p. 1236-1243 8 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2014

The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In: Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

2011

Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In: Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

2015

Targets in anticancer research-a review

Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In: Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

2016

An insight in to the efficacy of dehydrozingerone against aluminium induced cognitive dysfunction in rats

Anusha, Chamallamudi, M. R., Mudgal, J. & Nampoothiri, M., 01-07-2016, In: International Journal of Pharmaceutical Sciences Review and Research. 39, 1, p. 70-73 4 p., 15.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Selected novel 5’-amino-2’-hydroxy-1, 3-diaryl-2- propen-1-ones arrest cell cycle of HCT-116 in G₀/G₁ phase

Simon, L., Srinivasan, K. K., Kumar, N., Reddy, N. D., Biswas, S., Mallikarjuna Rao, C. & Moorkoth, S., 13-01-2016, In: EXCLI Journal. 15, p. 21-32 12 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

Reddy, N. D., Shoja, M. H., Biswas, S., Nayak, P. G., Kumar, N. & Rao, C. M., 25-06-2016, In: Chemico-Biological Interactions. 253, p. 112-124 13 p.

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

2014

Influence of milk components in establishing biofilm mediated bacterial mastitis infections in cattle: A fractional factorial approach

Atulya, M., Jesil Mathew, A., Venkata Rao, J. & Mallikarjuna Rao, C., 02-2014, In: Research in Veterinary Science. 96, 1, p. 25-27 3 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

2020

A Review on Anticancer Potentials of Benzothiazole Derivatives

Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In: Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Radiotherapy and its impact on the nervous system of cancer survivors

Kumar, G., Dutta, P., Parihar, V. K., Chamallamudi, M. R. & Kumar, N., 2020, In: CNS and Neurological Disorders - Drug Targets. 19, 5, p. 374-385 12 p.

Research output: Contribution to journal › Review article › peer-review

An appraisal of current pharmacological perspectives of sesamol: A review

Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In: Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

2016

Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride

Jetti, R., Raghuveer, C. & Rao, M. C., 2016, In: Toxicology and Industrial Health. 32, 1, p. 183-187 5 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2011

Effect of lecithin on d-galactosamine induced hepatotoxicity through mitochondrial pathway involving Bcl-2 and Bax

Raj, P. V., Nitesh, K., Prateek, J., Sankhe, M. N., Rao, J. V., Rao, C. M. & Udupa, N., 10-2011, In: Indian Journal of Clinical Biochemistry. 26, 4, p. 378-384 7 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2016

In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In: Frontiers in Pharmacology. 7, OCT, 381.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

2019

Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In: Inflammopharmacology. 27, 5, p. 941-948 8 p.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In: Pharmacology. 103, 5-6, p. 315-319 5 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

2012

Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

2019

Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In: Experimental Gerontology. 125, 1 p.

Research output: Contribution to journal › Article › peer-review

2020

Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In: European Journal of Medicinal Chemistry. 201, 112335.

Research output: Contribution to journal › Article › peer-review

2016

Preclinical efficacy of a gastro-sparing novel thiazolidin-4-one in alleviating secondary lesions of polyarthritis: A multi-parametric approach

Mudgal, J., Gowdra, V. S., Mudgal, P. P., Nayak, P. G., Kumar, N., Attari, Z., Rao, C. M. & Nampurath, G. K., 25-08-2016, In: European Journal of Pharmaceutical Sciences. 91, p. 74-83 10 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

2011

Ameliorative effect of caffeic acid against inflammatory pain in rodents

Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In: European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

2014

Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In: Pharmacological Reports. 66, 5, p. 788-798 11 p.

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

2019

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In: Pharmacological Reports. 71, 4, p. 703-712 10 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2017

Temozolomide and its stability—a critical factor

Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

2016

Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo

Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 01-09-2016, In: Clinical and Experimental Pharmacology and Physiology. 43, 9, p. 862-863 2 p.

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Naringin and rutin alleviates episodic memory deficits in two differentially challenged object recognition tasks

Ramalingayya, G. V., Nampoothiri, M., Nayak, P. G., Kishore, A., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 2016, In: Pharmacognosy Magazine. 12, 45, p. S63-S70

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

2011

Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2,1,b]-benzothiazole derivatives

Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Mallikarjuna Rao, C. & Barve, A., 10-2011, In: Letters in Drug Design and Discovery. 8, 8, p. 717-724 8 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

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