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• 2020

  Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

  Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In: European Journal of Medicinal Chemistry. 201, 112335.

  Research output: Contribution to journal › Article › peer-review

  • isocoumarin 3
  • Rosuvastatin Calcium
  • Cells
  • Antineoplastic Agents
  • Ultrasonics
• 2014

  Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

  Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In: Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Tumors
  • Derivatives
  • Liquids
  • Cytotoxicity
  18 Citations (Scopus)
• 2011

  Ameliorative effect of caffeic acid against inflammatory pain in rodents

  Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In: European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Rodentia
  • Pain
  • Analgesics
  • Nitrites
  53 Citations (Scopus)
• 2014

  Influence of milk components in establishing biofilm mediated bacterial mastitis infections in cattle: A fractional factorial approach

  Atulya, M., Jesil Mathew, A., Venkata Rao, J. & Mallikarjuna Rao, C., 02-2014, In: Research in Veterinary Science. 96, 1, p. 25-27 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Mastitis
  • milk composition
  • biofilm
  • mastitis
  • Biofilms
  12 Citations (Scopus)

• Synthesis, characterization, and preclinical evaluation of new thiazolidin-4-ones substituted with p-chlorophenoxy acetic acid and clofibric acid against insulin resistance and metabolic disorder

  Gowdra, V. S., Mudgal, J., Bansal, P., Nayak, P. G., Manohara Reddy, S. A., Shenoy, G. G., Valiathan, M., Chamallamudi, M. R. & Nampurath, G. K., 2014, In: BioMed Research International. 2014, 620434.

  Research output: Contribution to journal › Article › peer-review

  • Clofibric Acid
  • Acetic Acid
  • Insulin Resistance
  • Hypoadiponectinemia
  • Medical problems
  4 Citations (Scopus)

• The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In: Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vernonia
  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  7 Citations (Scopus)
• 2015

  The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  • Neoplasms
  10 Citations (Scopus)
• 2011

  Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

  Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In: Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quinoxalines
  • Derivatives
  • Antioxidants
  • Anti-Inflammatory Agents
  • Ricinoleic Acids
  21 Citations (Scopus)
• 2015

  Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In: Journal of Ethnopharmacology. 168, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Cell Cycle Checkpoints
  • Caspase 3
  • Breast Neoplasms
  • lupeol
  20 Citations (Scopus)
• 2011

  Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

  Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In: Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Terminalia
  • Anti-Inflammatory Agents
  • Freund's Adjuvant
  • Carrageenan
  • Inflammation
  39 Citations (Scopus)

• Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2,1,b]-benzothiazole derivatives

  Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Mallikarjuna Rao, C. & Barve, A., 10-2011, In: Letters in Drug Design and Discovery. 8, 8, p. 717-724 8 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Proton Magnetic Resonance Spectroscopy
  • MCF-7 Cells
  • Inhibitory Concentration 50
  4 Citations (Scopus)
• 2014

  Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

  Nampoothiri, M., Reddy, N. D., John, J., Kumar, N., Kutty Nampurath, G. & Rao Chamallamudi, M., 2014, In: Behavioural Neurology. 2014, 674164.

  Research output: Contribution to journal › Article › peer-review

  • Glutamic Acid
  • Insulin
  • Reactive Oxygen Species
  • Acridine Orange
  • Ethidium
  33 Citations (Scopus)
• 2015

  Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

  Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In: International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Sun hoods
  • Radiation protection
  • Antioxidants
  • Radiation Protection
  40 Citations (Scopus)
• 2014

  Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 673248.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Rats
  • Acetic Acid
  • acetic acid
  • Peroxidase
  8 Citations (Scopus)

• Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 430734.

  Research output: Contribution to journal › Comment/debate › peer-review
  5 Citations (Scopus)

• Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

  Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In: BioMed Research International. 2014, 569130.

  Research output: Contribution to journal › Article › peer-review

  • Dimenhydrinate
  • Aberrant Crypt Foci
  • 1,2-Dimethylhydrazine
  • Colonic Neoplasms
  • N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
  6 Citations (Scopus)
• 2011

  Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats

  Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 27-01-2011, In: Journal of Ethnopharmacology. 133, 2, p. 608-612 5 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Sesamum
  • Wound Healing
  • Dexamethasone
  • Protein-Lysine 6-Oxidase
  34 Citations (Scopus)
• 2015

  Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

  Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In: Pharmacognosy Magazine. 11, 44, p. S296-S302

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Curcumin
  • Inflammatory Bowel Diseases
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  11 Citations (Scopus)
• 2011

  High performance liquid chromatographic fluorescence detection method for the quantification of rivastigmine in rat plasma and brain: Application to preclinical pharmacokinetic studies in rats

  Arumugam, K., Chamallamudi, M. R., Mallayasamy, S. R., Mullangi, R., Ganesan, S., Jamadar, L., Ranjithkumar, A. & Udupa, N., 2011, In: Journal of Young Pharmacists. 3, 4, p. 315-321 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivastigmine
  • Fluorescence
  • Pharmacokinetics
  • ammonium acetate
  • Liquid-Liquid Extraction
  10 Citations (Scopus)
• 2020

  Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

  Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 01-11-2020, In: Andrologia.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Computer Simulation
  • Sildenafil Citrate
  • Spermatozoa
  • Testis

• Corrigendum: Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress (Biomed Rep, (2019) 11, (79-84), 10.3892/br.2019.1226)

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 2020, In: Biomedical Reports. 13, 3, p. 1 1 p., 19.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Catalase
  • Sprague Dawley Rats

• Cinnamyl Sulfonamide Hydroxamate Derivatives Inhibited LPS-Stimulated NF-kB Expression in RAW 264.7 Cells in In Vitro and Mitigated Experimental Colitis in Wistar Rats in In Vivo

  Joshi, M., Reddy, N. D., Kumara, N., Sumalatha, S. & Rao, C. M., 24-06-2020, In: Current Pharmaceutical Design.

  Research output: Contribution to journal › Article › peer-review

  • RAW 264.7 Cells
  • Sulfonamides
  • NF-kappa B
  • Colitis
  • Lipopolysaccharides

• Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

  Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In: 3 Biotech. 10, 4, 149.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • islets of Langerhans
  • Simvastatin
  • Mitochondrial Membrane Potential
  • Insulin-Secreting Cells
  1 Citation (Scopus)
• 2014

  Curriculum for pharmacology in pharmacy institutions in India: Opportunities and challenges

  Goyal, R. K., Bhise, S. B., Srinivasan, B. P., Rao, C. M., Sen, T. & Koneri, R., 2014, In: Indian Journal of Pharmacology. 46, 3, p. 241-245 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Molecular Farming
  • Pharmacy
  • Curriculum
  • India
  • Pharmacology
  3 Citations (Scopus)
• 2020

  Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

  Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In: 3 Biotech. 10, 10, 438.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • cognitive disorders
  • glioma
  • Temozolomide
  • Glioma
• 2015

  In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

  Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In: Chemico-Biological Interactions. 233, p. 81-94 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Cells
  • Enzyme inhibition
  • Derivatives
  • Colon
  20 Citations (Scopus)
• 2014

  Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

  Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In: Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Carrageenan
  • Rats
  • Dinoprostone
  • Cytokines
  • Inflammation
  10 Citations (Scopus)
• 2011

  Effect of lecithin on d-galactosamine induced hepatotoxicity through mitochondrial pathway involving Bcl-2 and Bax

  Raj, P. V., Nitesh, K., Prateek, J., Sankhe, M. N., Rao, J. V., Rao, C. M. & Udupa, N., 10-2011, In: Indian Journal of Clinical Biochemistry. 26, 4, p. 378-384 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Galactosamine
  • Lecithins
  • Liver
  • Rats
  • Messenger RNA
  8 Citations (Scopus)
• 2014

  Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

  Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In: Pharmacological Reports. 66, 5, p. 788-798 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Silybin
  • Silymarin
  • Liposomes
  • Biological Availability
  • Hepatocytes
  57 Citations (Scopus)
• 2020

  Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

  Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2020, In: Journal of Functional Foods. 103638.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Coffee
  • anxiety
  • caffeine
  3 Citations (Scopus)
• 2011

  Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2, 1, b]-benzothiazole derivatives

  Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Rao, M. C. & Barve, A., 11-2011, In: Letters in Drug Design and Discovery. 8, 9, p. 717-724 8 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Proton Magnetic Resonance Spectroscopy
  • MCF-7 Cells
  • Inhibitory Concentration 50
• 2020

  Evaluation of hepatoprotective effect of a polyherbal megakutki against paracetamol-induced hepatotoxicity

  Elizabeth Giri, A., Rao, V., Singhal, S., Gourishetti, K., Biswas, S., Nandakumar, K., Chamllamudi, M. R., Dave, J., Dave, R., Sumalatha, S. & Kumar, N., 01-10-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 4, p. 1080-1088 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetaminophen
  • Silymarin
  • Inhibitory Concentration 50
  • In Vitro Techniques
  • DNA Fragmentation

• An appraisal of current pharmacological perspectives of sesamol: A review

  Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In: Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • sesamol
  • Pharmacology
  • Sesamum
  • microbial metalloproteinases
  • Anti-Inflammatory Agents

• A Review on Anticancer Potentials of Benzothiazole Derivatives

  Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In: Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Structure-Activity Relationship
  • Thiazoles
  • Cell Line
  • Neoplasms
  2 Citations (Scopus)
• 2011

  Development and validation of a HPLC method for quantification of rivastigmine in rat urine and identification of a novel metabolite in urine by LC-MS/MS

  Arumugam, K., Chamallamudi, M. R., Gilibili, R. R., Mullangi, R., Ganesan, S., Kar, S. S., Averineni, R., Shavi, G. & Udupa, N., 03-2011, In: Biomedical Chromatography. 25, 3, p. 353-361 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivastigmine
  • Metabolites
  • Rats
  • High Pressure Liquid Chromatography
  • Urine
  17 Citations (Scopus)
• 2020

  Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

  Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Factors
  • Biological Products
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Drug Compounding
  2 Citations (Scopus)
• 2015

  Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

  John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Aluminum Chloride
  • Lipids
  • Frontal Lobe
  • Hippocampus
  26 Citations (Scopus)
• 2020

  Radiotherapy and its impact on the nervous system of cancer survivors

  Kumar, G., Dutta, P., Parihar, V. K., Chamallamudi, M. R. & Kumar, N., 2020, In: CNS and Neurological Disorders - Drug Targets. 19, 5, p. 374-385 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cancer Survivors
  • Nervous System
  • Radiotherapy
  • Cognition
  • Search Engine
• 2015

  Modulatory role of simvastatin against aluminium chloride-induced behavioural and biochemical changes in rats

  Nampoothiri, M., John, J., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 2015, In: Behavioural Neurology. 2015, 210169.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Simvastatin
  • Aluminum
  • Frontal Lobe
  • Hippocampus
  44 Citations (Scopus)

• Targets in anticancer research-a review

  Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In: Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmaceutical Preparations
  • Clinical Trials
  • Aromatase
  • Histone Deacetylases
  • Cyclin-Dependent Kinases
  12 Citations (Scopus)
• 2011

  Pro-healing effects of morin, a natural antioxidant, on normal and dexamethasone-impaired wounds

  Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 12-2011, In: Journal of Basic and Clinical Physiology and Pharmacology. 22, 4, p. 131-135 5 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Dexamethasone
  • Antioxidants
  • Wounds and Injuries
  • Granulation Tissue
  1 Citation (Scopus)

• Effect of Dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats

  Rao, M. C., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, G. N. & Shenoy, R. R., 09-2011, In: Molecular and Cellular Biochemistry. 355, 1-2, p. 249-256 8 p.

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Rats
  • Curcumin
  • Dexamethasone
  • Wound Healing
  15 Citations (Scopus)