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• 2020

  Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

  Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In: European Journal of Medicinal Chemistry. 201, 112335.

  Research output: Contribution to journal › Article › peer-review

  • isocoumarin 3
  • Rosuvastatin Calcium
  • Cells
  • Antineoplastic Agents
  • Ultrasonics
• 2012

  Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)
• 2017

  Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

  Wankhede, S., Kumar, N., Simon, L., Biswas, S., Gourishetti, K., Ramalingayya, G. V., Joshi, M. & Rao, C. M., 19-10-2017, In: EXCLI Journal. 16, p. 1150-1163 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcones
  • chalcones
  • breast neoplasms
  • Tumor Burden
  • neoplasms
• 2015

  Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In: Journal of Ethnopharmacology. 168, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Cell Cycle Checkpoints
  • Caspase 3
  • Breast Neoplasms
  • lupeol
  20 Citations (Scopus)
• 2017

  Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

  Ramalingayya, G. V., Cheruku, S. P., Nayak, P. G., Kishore, A., Shenoy, R., Rao, M. & Krishnadas, N., 29-03-2017, In: Drug Design, Development and Therapy. 11, p. 1011-1026 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutin
  • Memory Disorders
  • Doxorubicin
  • Wistar Rats
  • In Vitro Techniques
  26 Citations (Scopus)
• 2015

  Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

  Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In: Pharmacognosy Magazine. 11, 44, p. S296-S302

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Curcumin
  • Inflammatory Bowel Diseases
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  11 Citations (Scopus)

• The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  • Neoplasms
  11 Citations (Scopus)

• Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

  Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In: International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Sun hoods
  • Radiation protection
  • Antioxidants
  • Radiation Protection
  40 Citations (Scopus)

• Targets in anticancer research-a review

  Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In: Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmaceutical Preparations
  • Clinical Trials
  • Aromatase
  • Histone Deacetylases
  • Cyclin-Dependent Kinases
  12 Citations (Scopus)
• 2017

  Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

  Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In: NeuroReport. 28, 9, p. 540-544 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Memory
  • Dementia
  • Insulin
  • Glucose
  12 Citations (Scopus)
• 2020

  Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

  Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 01-11-2020, In: Andrologia.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Computer Simulation
  • Sildenafil Citrate
  • Spermatozoa
  • Testis

• Corrigendum: Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress (Biomed Rep, (2019) 11, (79-84), 10.3892/br.2019.1226)

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 2020, In: Biomedical Reports. 13, 3, p. 1 1 p., 19.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Catalase
  • Sprague Dawley Rats

• Cinnamyl Sulfonamide Hydroxamate Derivatives Inhibited LPS-Stimulated NF-kB Expression in RAW 264.7 Cells in In Vitro and Mitigated Experimental Colitis in Wistar Rats in In Vivo

  Joshi, M., Reddy, N. D., Kumara, N., Sumalatha, S. & Rao, C. M., 24-06-2020, In: Current Pharmaceutical Design.

  Research output: Contribution to journal › Article › peer-review

  • RAW 264.7 Cells
  • Sulfonamides
  • NF-kappa B
  • Colitis
  • Lipopolysaccharides
• 2017

  Insulin Combined with Glucose Improves Spatial Learning and Memory in Aluminum Chloride-Induced Dementia in Rats

  Nampoothiri, M., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-01-2017, In: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 36, 2, p. 159-169 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Learning
  • Rats
  • Spatial Memory
  • Dementia
  4 Citations (Scopus)
• 2015

  In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

  Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In: Chemico-Biological Interactions. 233, p. 81-94 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Cells
  • Enzyme inhibition
  • Derivatives
  • Colon
  20 Citations (Scopus)
• 2017

  In vitro and in vivo anticancer studies of 2′-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by hdac inhibition and cell cycle arrest

  Pande, A. N., Biswas, S., Reddy, N. D., Jayashree, B. S., Kumar, N. & Rao, C. M., 03-04-2017, In: EXCLI Journal. 16, p. 448-463 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcone
  • chalcone
  • cell cycle checkpoints
  • colorectal neoplasms
  • Cell Cycle Checkpoints
  14 Citations (Scopus)
• 2020

  Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

  Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In: 3 Biotech. 10, 10, 438.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • cognitive disorders
  • glioma
  • Temozolomide
  • Glioma

• Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

  Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In: 3 Biotech. 10, 4, 149.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • islets of Langerhans
  • Simvastatin
  • Mitochondrial Membrane Potential
  • Insulin-Secreting Cells
  1 Citation (Scopus)
• 2012

  Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)
• 2020

  Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

  Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2020, In: Journal of Functional Foods. 103638.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Coffee
  • anxiety
  • caffeine
  3 Citations (Scopus)
• 2017

  Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

  Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon tetrachloride
  • Liver
  • Toxicity
  • Carbon
  • Carbon Tetrachloride
  1 Citation (Scopus)
• 2012

  Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)
• 2020

  Evaluation of hepatoprotective effect of a polyherbal megakutki against paracetamol-induced hepatotoxicity

  Elizabeth Giri, A., Rao, V., Singhal, S., Gourishetti, K., Biswas, S., Nandakumar, K., Chamllamudi, M. R., Dave, J., Dave, R., Sumalatha, S. & Kumar, N., 01-10-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 4, p. 1080-1088 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetaminophen
  • Silymarin
  • Inhibitory Concentration 50
  • In Vitro Techniques
  • DNA Fragmentation

• An appraisal of current pharmacological perspectives of sesamol: A review

  Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In: Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • sesamol
  • Pharmacology
  • Sesamum
  • microbial metalloproteinases
  • Anti-Inflammatory Agents
• 2017

  Temozolomide and its stability—a critical factor

  Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • Drugs
  • drug
  • Degradation
  • Pharmaceutical Preparations
  1 Citation (Scopus)
• 2020

  Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

  Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Factors
  • Biological Products
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Drug Compounding
  2 Citations (Scopus)
• 2015

  Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

  John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Aluminum Chloride
  • Lipids
  • Frontal Lobe
  • Hippocampus
  26 Citations (Scopus)
• 2012

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)
• 2020

  Radiotherapy and its impact on the nervous system of cancer survivors

  Kumar, G., Dutta, P., Parihar, V. K., Chamallamudi, M. R. & Kumar, N., 2020, In: CNS and Neurological Disorders - Drug Targets. 19, 5, p. 374-385 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cancer Survivors
  • Nervous System
  • Radiotherapy
  • Cognition
  • Search Engine
• 2015

  Modulatory role of simvastatin against aluminium chloride-induced behavioural and biochemical changes in rats

  Nampoothiri, M., John, J., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 2015, In: Behavioural Neurology. 2015, 210169.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Simvastatin
  • Aluminum
  • Frontal Lobe
  • Hippocampus
  44 Citations (Scopus)
• 2017

  Epigenetics in cancer: Fundamentals and Beyond

  Biswas, S. & Rao, C. M., 01-05-2017, In: Pharmacology and Therapeutics. 173, p. 118-134 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Neoplasms
  • Carcinogenesis
  • Nucleosomes
  • Gene Targeting
  86 Citations (Scopus)
• 2020

  A Review on Anticancer Potentials of Benzothiazole Derivatives

  Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In: Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Structure-Activity Relationship
  • Thiazoles
  • Cell Line
  • Neoplasms
  3 Citations (Scopus)