Find Research outputs — Manipal Academy of Higher Education, Manipal, India

Active Targeting of Drugs and Bioactive Molecules via Oral Administration by Ligand-Conjugated Lipidic Nanocarriers: Recent Advances

Shreya, A. B., Raut, S. Y., Managuli, R. S., Udupa, N. & Mutalik, S., 01-01-2019, In: AAPS PharmSciTech. 20, 1, 15.

Research output: Contribution to journal › Review article › peer-review

Antidiabetic drug metformin affects the developmental competence of cleavage-stage embryos

Nayak, G., Salian, S. R., Agarwal, P., Suresh Poojary, P., Rao, A., Kumari, S., Kalthur, S. G., Shreya, A. B., Mutalik, S., Adiga, S. K. & Kalthur, G., 01-05-2020, In: Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journal › Article › peer-review

Application of hot melt extrusion for the solubility enhancement of a BCS class II drug

Kumar, A. M. S., Kulyadi, G. P., Mutalik, S., Kulkarni, V. I. & Tippavajhala, V. K., 08-2019, In: Research Journal of Pharmacy and Technology. 12, 8, p. 3751-3754 4 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Asenapine maleate-loaded nanostructured lipid carriers: Optimization and in vitro, ex vivo and in vivo evaluations

Managuli, R. S., Wang, J. T., Faruqu, F. N., Kushwah, V., Raut, S. Y., Shreya, A. B., Al-Jamal, K. T., Jain, S. & Mutalik, S., 01-04-2019, In: Nanomedicine. 14, 7, p. 889-910 22 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Biogenic synthesis of silver nanoparticles using Jatropha curcas seed cake extract and characterization: evaluation of its antibacterial activity

Nayak, S., Sajankila, S. P., Rao, C. V., Hegde, A. R. & Mutalik, S., 01-01-2019, (Accepted/In press) In: Energy Sources, Part A: Recovery, Utilization and Environmental Effects.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Challenges in the development of analytical test procedure for aminoglycosides: A critical review

Hari, R., Taherunnisa, S., Raut, S. Y., Mutalik, S. & Koteshwara, K. B., 01-01-2019, In: Journal of Applied Pharmaceutical Science. 9, 11, p. 145-152 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

Complex injectables: Development, delivery, and advancement. Development, delivery, and advancement

Pandey, A., Singh, D., Dhas, N., Tewari, A. K., Pathak, K., Chatap, V., Rathore, K. S. & Mutalik, S., 04-02-2020, Delivery of Drugs: Volume 2: Expectations and Realities of Multifunctional Drug Delivery Systems. Elsevier Inc., p. 191-213 23 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Copper sulphide based heterogeneous nanoplatforms for multimodal therapy and imaging of cancer: Recent advances and toxicological perspectives

Nikam, A. N., Pandey, A., Fernandes, G., Kulkarni, S., Mutalik, S. P., Padya, B. S., George, S. D. & Mutalik, S., 15-09-2020, In: Coordination Chemistry Reviews. 419, 213356.

Research output: Contribution to journal › Review article › peer-review

Correction to: Once-daily sustained-release matrix tablets of nicorandil: Formulation and in vitro evaluation (AAPS PharmSciTech, (2003), 4, 4, (480-488), 10.1208/pt040461)

Kasu, R. R. R., Mutalik, S. & Reddy, S., 01-07-2020, In: AAPS PharmSciTech. 21, 5, 197.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

1 Citation (Scopus)

Cyclodextrins as Carriers in Targeted Delivery of Therapeutic Agents: Focused Review on Traditional and Inimitable Applications

Raut, S. Y., Manne, A. S. N., Kalthur, G., Jain, S. & Mutalik, S., 01-01-2019, In: Current Pharmaceutical Design. 25, 4, p. 444-454 11 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Delving deeper into dermal and transdermal drug delivery: Factors and mechanisms associated with nanocarrier-mediated strategies

Manikkath, J., Sumathy, T. K., Manikkath, A. & Mutalik, S., 01-01-2018, In: Current Pharmaceutical Design. 24, 27, p. 3210-3222 13 p.

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Emerging era of “somes”: polymersomes as versatile drug delivery carrier for cancer diagnostics and therapy

Sharma, A. K., Prasher, P., Aljabali, A. A., Mishra, V., Gandhi, H., Kumar, S., Mutalik, S., Chellappan, D. K., Tambuwala, M. M., Dua, K. & Kapoor, D. N., 01-10-2020, In: Drug Delivery and Translational Research.

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress

Hegde, S., Poojary, K. K., Rasquinha, R., Crasta, D. N., Gopalan, D., Mutalik, S., Siddiqui, S., Adiga, S. K. & Kalthur, G., 01-07-2020, In: Pesticide Biochemistry and Physiology. 104588.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Ethanolic extract of Moringa oleifera leaves alleviate cyclophosphamide-induced testicular toxicity by improving endocrine function and modulating cell specific gene expression in mouse testis

Nayak, G., Rao, A., Mullick, P., Mutalik, S., Kalthur, S. G., Adiga, S. K. & Kalthur, G., 15-09-2020, In: Journal of Ethnopharmacology. 259, 112922.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Exposure to first line anti-tuberculosis drugs in prepubertal age reduces the quality and functional competence of spermatozoa and oocytes in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Kalthur, S. G., Mutalik, S. P., Mutalik, S., Adiga, S. K. & Kalthur, G., 01-2020, In: Environmental Toxicology and Pharmacology. 73, 103292.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Factors affecting the morphology of some organic and inorganic nanostructures for drug delivery: characterization, modifications, and toxicological perspectives

Raychaudhuri, R., Pandey, A., Hegde, A., Abdul Fayaz, S. M., Chellappan, D. K., Dua, K. & Mutalik, S., 2020, In: Expert Opinion on Drug Delivery.

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Formulation and evaluation of compression coated tablets for controlled release of cefadroxil monohydrate

Paruti, M. P., Alange, V. V., Mutalik, S., Naikawade, A. A. & Kulkarni, R. V., 2013, In: Research Journal of Pharmacy and Technology. 6, 4, p. 356-359 4 p.

Research output: Contribution to journal › Article › peer-review

Formulation and evaluation of multiparticulate drug delivery system of valsartan

Nayak, U. Y., Shavi, G. V., Mutalik, S. & Udupa, N., 2013, In: Research Journal of Pharmacy and Technology. 6, 1, p. 96-104 9 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Full factorial experimental design for development and validation of a RP-HPLC method for estimation of letrozole in nanoformulations

Hegde, A. R., Managuli, R. S., Naha, A., Koteshwara, K. B., Reddy, M. S. & Mutalik, S., 01-05-2018, In: Current Pharmaceutical Analysis. 14, 3, p. 320-330 11 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Heterogeneous surface architectured metal-organic frameworks for cancer therapy, imaging, and biosensing: A state-of-the-art review

Pandey, A., Dhas, N., Deshmukh, P., Caro, C., Patil, P., Luisa García-Martín, M., Padya, B., Nikam, A., Mehta, T. & Mutalik, S., 01-05-2020, In: Coordination Chemistry Reviews. 409, 213212.

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

Heterogeneous surface-modified nanoplatforms for the targeted therapy of haematological malignancies

Kulkarni, S., Pandey, A. & Mutalik, S., 01-01-2020, In: Drug Discovery Today.

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

High-fat diet leads to elevated lipid accumulation and endoplasmic reticulum stress in oocytes, causing poor embryo development

Rao, A., Satheesh, A., Nayak, G., Poojary, P. S., Kumari, S., Kalthur, S. G., Mutalik, S., Adiga, S. K. & Kalthur, G., 10-2020, In: Reproduction, Fertility and Development.

Research output: Contribution to journal › Article › peer-review

Hot liquid extrusion assisted drug-cyclodextrin complexation: a novel continuous manufacturing method for solubility and bioavailability enhancement of drugs

Manne, A. S. N., Hegde, A. R., Raut, S. Y., Rao, R. R., Kulkarni, V. I. & Mutalik, S., 2020, (Accepted/In press) In: Drug Delivery and Translational Research.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Hyaluronic acid-drug conjugate modified core-shell MOFs as pH responsive nanoplatform for multimodal therapy of glioblastoma

Pandey, A., Kulkarni, S., Vincent, A. P., Nannuri, S. H., George, S. D. & Mutalik, S., 15-10-2020, In: International Journal of Pharmaceutics. 588, 119735.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Interpenetrating polymer network microcapsules of gellan gum and egg albumin entrapped with diltiazem-resin complex for controlled release application

Kulkarni, R. V., Mangond, B. S., Mutalik, S. & Sa, B., 2011, In: Carbohydrate Polymers. 83, 2, p. 1001-1007 7 p.

Research output: Contribution to journal › Article › peer-review

80 Citations (Scopus)

Intraoral slow-releasing polymeric patches containing sodium fluoride and chlorhexidine: Development and evaluation

Karuna, Y. M., Nayak, A. P., Pralhad, S., Mutalik, S. & Padya, B. S., 10-2020, In: Journal of Applied Pharmaceutical Science. 10, 10, p. 30-35 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Iontophoresis-mediated transdermal permeation of peptide dendrimers across human epidermis

Mutalik, S., Parekh, H. S., Anissimov, Y. G., Grice, J. E. & Roberts, M. S., 2013, In: Skin Pharmacology and Physiology. 26, 3, p. 127-138 12 p.

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Liquid metal based theranostic nanoplatforms: Application in cancer therapy, imaging and biosensing

Kulkarni, S., Pandey, A. & Mutalik, S., 06-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 26, 102175.

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In: International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Nanoarchitectronics: A versatile tool for deciphering nanoparticle interaction with cellular proteins, nucleic acids and phospholipids at biological interfaces

Mutalik, S. P., Pandey, A. & Mutalik, S., 15-05-2020, In: International Journal of Biological Macromolecules. 151, p. 136-158 23 p.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Nanocomposite clay-polymer microbeads for oral controlled drug delivery: Development and, in vitro and in vivo evaluations

Raut, S. Y., Gahane, A., Joshi, M. B., Kalthur, G. & Mutalik, S., 01-06-2019, In: Journal of Drug Delivery Science and Technology. 51, p. 234-243 10 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Naringin nano-ethosomal novel sunscreen creams: Development and performance evaluation

Gollavilli, H., Hegde, A. R., Managuli, R. S., Bhaskar, K. V., Dengale, S. J., Reddy, M. S., Kalthur, G. & Mutalik, S., 09-2020, In: Colloids and Surfaces B: Biointerfaces. 193, 111122.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Neuroprotection: A versatile approach to combat glaucoma

Naik, S., Pandey, A., Lewis, S. A., Rao, B. S. S. & Mutalik, S., 15-08-2020, In: European Journal of Pharmacology. 881, 173208.

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Novel interpenetrated polymer network microbeads of natural polysaccharides for modified release of water soluble drug: In-vitro and in-vivo evaluation

Kulkarni, R. V., Mutalik, S., Mangond, B. S. & Nayak, U. Y., 2012, In: Journal of Pharmacy and Pharmacology. 64, 4, p. 530-540 11 p.

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Novel oral drug delivery systems for steroids: Overview and recent updates

Ganapa, M. S., Mhatre, S. S., Raut, S. Y., Pandey, A., Kalthur, G. & Mutalik, S., 01-07-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 3, p. 541-549 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo evaluation

Boppana, R., Yadaorao Raut, S., Krishna Mohan, G., Sa, B., Mutalik, S., Reddy, K. R., Das, K. K., Biradar, M. S. & Kulkarni, R. V., 01-08-2019, In: Colloids and Surfaces B: Biointerfaces. 180, p. 362-370 9 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Pediatric dosage forms-challenges and recent developments: A critical review

Galande, A. D., Khurana, N. A. & Mutalik, S., 01-07-2020, In: Journal of Applied Pharmaceutical Science. 10, 7, p. 155-166 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Pharmaceutical applications of radio-frequency identification

Kalra, R., Shetty, P., Mutalik, S., Nayak, U., Reddy, M. & Udupa, N., 01-2012, In: Systematic Reviews in Pharmacy. 3, 1, p. 24-30 7 p.

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

PH-responsive interpenetrating network hydrogel beads of poly(acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in vivo evaluation

Kulkarni, R. V., Boppana, R., Krishna Mohan, G., Mutalik, S. & Kalyane, N. V., 2012, In: Journal of Colloid and Interface Science. 367, 1, p. 509-517 9 p.

Research output: Contribution to journal › Article › peer-review

103 Citations (Scopus)

Polymethacrylate coated valsartan tablets for ileo-colonic delivery: Formulation development and in vitro and in vivo evaluations

Nayak, U. Y., Mutalik, S. & Nayak, Y., 2013, In: Research Journal of Pharmacy and Technology. 6, 12, p. 1362-1369 8 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

Pandey, A., Nikam, A. N., Shreya, A. B., Mutalik, S. P., Gopalan, D., Kulkarni, S., Padya, B. S., Fernandes, G., Mutalik, S. & Prassl, R., 01-09-2020, In: Life Sciences. 256, 117883.

Research output: Contribution to journal › Review article › peer-review

27 Citations (Scopus)

Pullulan based stimuli responsive and sub cellular targeted nanoplatforms for biomedical application: Synthesis, nanoformulations and toxicological perspective

Raychaudhuri, R., Naik, S., Shreya, A. B., Kandpal, N., Pandey, A., Kalthur, G. & Mutalik, S., 15-10-2020, In: International Journal of Biological Macromolecules. 161, p. 1189-1205 17 p.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Quinoline Derivative Enhances Human Sperm Motility and Improves the Functional Competence

Kumari, S., Salian, S. R., Rao, A., Somagond, S. M., Kamble, R. R., Nesaragi, A., Das, J., Rajanikant, G. K., Mutalik, S., Raghu, S. V., Adiga, S. K. & Kalthur, G., 2020, (Accepted/In press) In: Reproductive Sciences.

Research output: Contribution to journal › Article › peer-review

Open Access

Recent Advancement in Bio-precursor derived graphene quantum dots: Synthesis, Characterization and Toxicological Perspective

Tade, R. S., Nangare, S. N., Patil, A. G., Pandey, A., Deshmukh, P. K., Patil, D. R., Agrawal, T. N., Mutalik, S., Patil, A. M., More, M. P., Bari, S. B. & Patil, P. O., 28-04-2020, In: Nanotechnology. 31, 29, 292001.

Research output: Contribution to journal › Review article › peer-review