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26 Citations (Scopus)

Addition of zinc to human ejaculate prior to cryopreservation prevents freeze-thaw-induced DNA damage and preserves sperm function

Kotdawala, A. P., Kumar, S., Salian, S. R., Thankachan, P., Govindraj, K., Kumar, P., Kalthur, G. & Adiga, S. K., 12-2012, In : Journal of Assisted Reproduction and Genetics. 29, 12, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

Cryopreservation
Semen
DNA Damage
Spermatozoa
Zinc
Assisted Reproductive Techniques
Chorionic Gonadotropin
Oocytes
Fertilization
Hormone Antagonists
32 Citations (Scopus)

A fast NMR method for resonance assignments: Application to metabolomics

Pudakalakatti, S. M., Dubey, A., Jaipuria, G., Shubhashree, U., Adiga, S. K., Moskau, D. & Atreya, H. S., 2014, In : Journal of Biomolecular NMR. 58, 3, p. 165-173 9 p.

Research output: Contribution to journalArticle

Metabolomics
Nuclear magnetic resonance
Fourier Analysis
Metabolites
Data acquisition
2 Citations (Scopus)
Insemination
Baths
Carbon Dioxide
Cost-Benefit Analysis
Spermatozoa
13 Citations (Scopus)

Association between sperm DNA integrity and seminal plasma antioxidant levels in health workers occupationally exposed to ionizing radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Jain, N., Krishnamurthy, H., Kumar, P. & Adiga, S. K., 2014, In : Environmental Research. 132, p. 297-304 8 p.

Research output: Contribution to journalArticle

health worker
Ionizing radiation
Ionizing Radiation
Semen
sperm

Barriers and Opportunities of Oncofertility Practice in Nine Developing Countries and the Emerging Oncofertility Professional Engagement Network

Salama, M., Ataman-Millhouse, L., Sobral, F., Terrado, G., Scarella, A., Bourlon, M. T., Adiga, S. K., Udupa, K. S., Mahajan, N., Patil, M., Venter, C., Demetriou, G., Quintana, R., Rodriguez, G., Quintana, T., Viale, L., Bonilla, Y. A. R., Noguera, J. A. R., Velásquez, J. C. V., Pineda, J. I. D. & 6 others, Aldecoa, M. D. C., Javed, M., Al Sufyan, H., Daniels, N., Ogunmokun, A. A. & Woodruff, T. K., 01-12-2018, In : Journal of global oncology. 4, p. 1-7 7 p.

Research output: Contribution to journalArticle

Developing Countries
Guatemala
Cultural Competency
Insurance Coverage
Colombia

Controlled cooling versus rapid freezing of teratozoospermic semen samples: Impact on sperm chromatin integrity

Kalludi, S. N., Kalthur, G., Benjamin, S., Kumar, P. & Adiga, S., 09-2011, In : Journal of Human Reproductive Sciences. 4, 3, p. 121-124 4 p.

Research output: Contribution to journalArticle

Semen
Freezing
Chromatin
Spermatozoa
DNA Damage
13 Citations (Scopus)
Octamer Transcription Factors
Superovulation
superovulation
Organelles
Oocytes
7 Citations (Scopus)

Ejaculate fractions of asthenozoospermic and teratozoospermic patients have differences in the sperm DNA integrity

Kumar, D., Kalthur, G., Mascarenhas, C., Kumar, P. & Adiga, S. K., 12-2011, In : Andrologia. 43, 6, p. 416-421 6 p.

Research output: Contribution to journalArticle

Spermatozoa
DNA
Semen
Comet Assay
Seminal Vesicles
1 Citation (Scopus)

Epigenetic changes in preimplantation embryos subjected to laser manipulation

Honguntikar, S. D., Salian, S. R., D’Souza, F., Uppangala, S., Kalthur, G. & Adiga, S. K., 01-12-2017, In : Lasers in Medical Science. 32, 9, p. 2081-2087 7 p.

Research output: Contribution to journalArticle

Blastocyst
Epigenomics
Lasers
Embryonic Structures
Transferases
3 Citations (Scopus)

Ethambutol induces testicular damage and decreases the sperm functional competence in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Prabhu, A. D., Khandige, N., Kalthur, S. G., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Environmental Toxicology and Pharmacology. 47, p. 28-37 10 p.

Research output: Contribution to journalArticle

Ethambutol
Mental Competency
Spermatozoa
Sperm Head
Sperm Count
11 Citations (Scopus)

Ethanolic extract of Moringa oleifera Lam. leaves protect the pre-pubertal spermatogonial cells from cyclophosphamide-induced damage

Nayak, G., Honguntikar, S. D., Kalthur, S. G., D'Souza, A. S., Mutalik, S., Setty, M. M., Kalyankumar, R., Krishnamurthy, H., Kalthur, G. & Adiga, S. K., 22-04-2016, In : Journal of Ethnopharmacology. 182, p. 101-109 9 p.

Research output: Contribution to journalArticle

Moringa oleifera
Germ Cells
Cyclophosphamide
DNA Damage
Body Weight
7 Citations (Scopus)
Povidone
DNA Fragmentation
Immobilization
Spermatozoa
Intracytoplasmic Sperm Injections
4 Citations (Scopus)
Plasma stability
Lymphocytes
Ionizing radiation
Ionizing Radiation
Health care
12 Citations (Scopus)

Germ cell abnormalities in streptozotocin induced diabetic mice do not correlate with blood glucose level

Bose, R., Adiga, S. K., D'Souza, F., Salian, S. R., Uppangala, S., Kalthur, G., Jain, N., Radhakrishnan, R. A., Bhat, N., Krishnamurthy, H. & Kumar, P., 12-2012, In : Journal of Assisted Reproduction and Genetics. 29, 12, p. 1405-1413 9 p.

Research output: Contribution to journalArticle

Streptozocin
Germ Cells
Blood Glucose
Ploidies
Spermatozoa
1 Citation (Scopus)
Haploidy
Ammonia
Embryonic Structures
Blastocyst
Parthenogenesis
5 Citations (Scopus)
Propolis
Mitomycin
DNA Damage
Antioxidants
Fertility Preservation
8 Citations (Scopus)

Influence of sperm DNA damage on human preimplantation embryo metabolism

Uppangala, S., Pudakalakatti, S., D'souza, F., Salian, S. R., Kalthur, G., Kumar, P., Atreya, H. & Adiga, S. K., 01-09-2016, In : Reproductive biology. 16, 3, p. 234-241 8 p.

Research output: Contribution to journalArticle

Blastocyst
DNA damage
DNA Damage
Spermatozoa
embryo (animal)
1 Citation (Scopus)

In situ viability detection assays induce heat-shock protein 70 expression in spermatozoa without affecting the chromatin integrity

Asokan, Y., Honguntikar, S. D., Uppangala, S., Salian, S. R., Kumar, D., Kalthur, G. & Adiga, S. K., 01-10-2015, In : Andrologia. 47, 8, p. 958-965 8 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Chromatin
Spermatozoa
Pentoxifylline
Sperm Head
2 Citations (Scopus)

In vitro matured oocytes are more susceptible than in vivo matured oocytes to mock ICSI induced functional and genetic changes

Uppangala, S., Dhiman, S., Salian, S. R., Singh, V. J., Kalthur, G. & Adiga, S. K., 18-03-2015, In : PLoS One. 10, 3, e0119735.

Research output: Contribution to journalArticle

Phosphorylation
Intracytoplasmic Sperm Injections
Oocytes
Reactive Oxygen Species
oocytes
7 Citations (Scopus)
Hormone Antagonists
Ovulation Induction
Follicle Stimulating Hormone
Luteinizing Hormone
Gonadotropin-Releasing Hormone
1 Citation (Scopus)
Sperm Head
Comet Assay
abnormality
DNA damage
sperm
6 Citations (Scopus)

Laser-assisted hatching of cleavage-stage embryos impairs developmental potential and increases DNA damage in blastocysts

Honguntikar, S. D., Uppangala, S., Salian, S. R., Kalthur, G., Kumar, P. & Adiga, S. K., 2014, In : Lasers in Medical Science. 30, 1, p. 95-101 7 p.

Research output: Contribution to journalArticle

Blastocyst
DNA Damage
Lasers
Embryonic Structures
Cell Count
5 Citations (Scopus)

Laser assisted zona hatching does not lead to immediate impairment in human embryo quality and metabolism

Uppangala, S., D’Souza, F., Pudakalakatti, S., Atreya, H. S., Raval, K., Kalthur, G. & Adiga, S. K., 01-11-2016, In : Systems Biology in Reproductive Medicine. 62, 6, p. 396-403 8 p.

Research output: Contribution to journalArticle

Herpes Zoster
Lasers
Embryonic Structures
Magnetic Resonance Spectroscopy
Assisted Reproductive Techniques
2 Citations (Scopus)
Inositol
Liposomes
Glycerol
Oocytes
Blastocyst
16 Citations (Scopus)

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

Nair, R., Singh, V. J., Salian, S. R., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Kalthur, G. & Adiga, S. K., 2014, In : Toxicology and Applied Pharmacology. 279, 3, p. 338-350 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Mitigating effect of Indian propolis against mitomycin C induced bone marrow toxicity

Kumari, S., Naik, P., Vishma, B. L., Salian, S. R., Devkar, R. A., Khan, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Cytotechnology. 68, 5, p. 1789-1800 12 p.

Research output: Contribution to journalArticle

Propolis
Mitomycin
Lipids
Toxicity
Assays
26 Citations (Scopus)

NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: A new biomarker for assessment of embryo implantation potential

Pudakalakatti, S. M., Uppangala, S., D'Souza, F., Kalthur, G., Kumar, P., Adiga, S. K. & Atreya, H. S., 01-2013, In : NMR in Biomedicine. 26, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

Assisted Reproductive Techniques
Blastocyst
Biomarkers
Pyruvic Acid
Metabolism
9 Citations (Scopus)
Herpes Zoster
DNA Fragmentation
Mental Competency
Spermatozoa
Zona Pellucida
2 Citations (Scopus)
Oocyte Retrieval
Reproduction
Pressure
Pregnancy Outcome
Intracytoplasmic Sperm Injections
1 Citation (Scopus)

Oocytes recovered after ovarian tissue slow freezing have impaired H2AX phosphorylation and functional competence

Sudhakaran, S., Uppangala, S., Salian, S. R., Honguntikar, S. D., Nair, R., Kalthur, G. & Adiga, S. K., 2015, In : Reproduction, Fertility and Development. 27, 8, p. 1242-1248 7 p.

Research output: Contribution to journalArticle

Mental Competency
Freezing
Oocytes
phosphorylation
freezing
16 Citations (Scopus)

Ovarian tissue vitrification is more efficient than slow freezing in protecting oocyte and granulosa cell DNA integrity

Mathias, F. J., D'souza, F., Uppangala, S., Salian, S. R., Kalthur, G. & Adiga, S. K., 01-12-2014, In : Systems Biology in Reproductive Medicine. 60, 6, p. 317-322 6 p.

Research output: Contribution to journalArticle

Vitrification
Granulosa Cells
Freezing
Oocytes
DNA
1 Citation (Scopus)

Phase modulated 2D HSQC-TOCSY for unambiguous assignment of overlapping spin systems

Singh, A., Dubey, A., Adiga, S. K. & Atreya, H. S., 01-01-2018, In : Journal of Magnetic Resonance. 286, p. 10-16 7 p.

Research output: Contribution to journalArticle

culture media
Assisted Reproductive Techniques
Molecules
Metabolomics
embryos
41 Citations (Scopus)

Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men

Varshini, J., Srinag, B. S., Kalthur, G., Krishnamurthy, H., Kumar, P., Rao, S. B. S. & Adiga, S. K., 05-2012, In : Andrologia. 44, SUPPL.1, p. 642-649 8 p.

Research output: Contribution to journalArticle

DNA Damage
Spermatozoa
Semen
Oligospermia
Varicocele

PPAR-gamma: A dagger in endometriosis

Amberkar, M. V., Meena Kumari, K., Mor, V., Semwal, A. & Adiga, S., 2010, In : Australasian Medical Journal. 3, 12, p. 814-820 7 p.

Research output: Contribution to journalArticle

Proteinaceous sperm motility inhibitory factor from the female Indian garden lizard Calotes versicolor

Shankar, G., Uppangala, S., Adiga, S. K., Willard, B., Sagar, B. K. C., Titus, R. S. K. & Marathe, G. K., 01-01-2018, In : Reproduction, Fertility and Development. 30, 5, p. 744-751 8 p.

Research output: Contribution to journalArticle

Lizards
Sperm Motility
sperm motility
lizards
Spermatozoa
11 Citations (Scopus)

Reduced expression of DNMT3B in the germ cells of patients with bilateral spermatogenic arrest does not lead to changes in the global methylation status

Adiga, S. K., Ehmcke, J., Schlatt, S., Kliesch, S., Westernströer, B., Luetjens, C. M., Wistuba, J. & Gromoll, J., 09-2011, In : Molecular Human Reproduction. 17, 9, p. 545-549 5 p., gar023.

Research output: Contribution to journalArticle

Germ Cells
Methylation
Spermatogenesis
5-Methylcytosine
Spermatocytes
33 Citations (Scopus)

Semen Abnormalities, Sperm DNA Damage and Global Hypermethylation in Health Workers Occupationally Exposed to Ionizing Radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Krishnamurthy, H., Jain, N., Kumar, P. & Adiga, S. K., 29-07-2013, In : PLoS One. 8, 7, e69927.

Research output: Contribution to journalArticle

Ionizing radiation
health care workers
Ionizing Radiation
Semen
ionizing radiation
2 Citations (Scopus)

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

D’Souza, F., Uppangala, S., Asampille, G., Salian, S. R., Kalthur, G., Talevi, R., Atreya, H. S. & Adiga, S. K., 01-12-2018, In : Scientific Reports. 8, 1, 17025.

Research output: Contribution to journalArticle

Blastocyst
Culture Media
Embryonic Structures
Pyruvic Acid
Injections
14 Citations (Scopus)

Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract

Nayak, G., Vadinkar, A., Nair, S., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Shetty, M. M., Kalthur, G. & Adiga, S. K., 01-03-2016, In : Andrologia. 48, 2, p. 125-136 12 p.

Research output: Contribution to journalArticle

Moringa oleifera
Cyclophosphamide
Spermatozoa
Injections
DNA Damage
6 Citations (Scopus)

Spermatozoada dna hasari{dotless}ni{dotless}n boyutu ile fertilizasyon ve implantasyon öncesi embriyolari{dotless}n gelişimsel kompetansi{dotless} arasi{dotless}ndaki ilişki

Translated title of the contribution: Association between the extent of DNA damage in the spermatozoa, fertilization and developmental competence in preimplantation stage embryosUpadhya, D., Kalthur, G., Kumar, P., Rao, B. S. & Adiga, S. K., 2010, In : Journal of the Turkish German Gynecology Association. 11, 4, p. 182-186 5 p.

Research output: Contribution to journalArticle

Blastocyst
Fertilization
Mental Competency
DNA Damage
Spermatozoa
3 Citations (Scopus)

Sperm chromatin immaturity observed in short abstinence ejaculates affects DNA integrity and longevity in vitro

Uppangala, S., Mathai, S. E., Salian, S. R., Kumar, D., Singh, V. J., D'Souza, F., Kalthur, G., Kamath, A. & Adiga, S. K., 01-04-2016, In : PLoS One. 11, 4, e0152942.

Research output: Contribution to journalArticle

Chromatin
chromatin
Spermatozoa
spermatozoa
DNA
1 Citation (Scopus)

Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 28-11-2017, (Accepted/In press) In : Zygote. p. 1-14 14 p.

Research output: Contribution to journalArticle

Haploidy
Spermatozoa
Oocytes
Status Epilepticus
Zygote
1 Citation (Scopus)

Sperm-mediated DNA lesions alter metabolite levels in spent embryo culture medium

Souza, F. D., Asampille, G., Uppangala, S., Kalthur, G., Atreya, H. S. & Adiga, S. K., 01-01-2019, In : Reproduction, Fertility and Development. 31, 3, p. 443-450 8 p.

Research output: Contribution to journalArticle

embryo culture
Culture Media
Spermatozoa
embryo (animal)
Embryonic Structures
48 Citations (Scopus)
DNA Damage
Spermatozoa
In Situ Nick-End Labeling
Oligospermia
Transferases

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Biotin
Embryonic Development
Spermatozoa
Pentoxifylline
Fertilization
8 Citations (Scopus)

Supplementation of biotin to sperm preparation medium increases the motility and longevity in cryopreserved human spermatozoa

Kalthur, G., Salian, S. R., Keyvanifard, F., Sreedharan, S., Thomas, J. S., Kumar, P. & Adiga, S. K., 07-2012, In : Journal of Assisted Reproduction and Genetics. 29, 7, p. 631-635 5 p.

Research output: Contribution to journalArticle

Biotin
Pentoxifylline
Spermatozoa
Semen
Semen Preservation
11 Citations (Scopus)

Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

Research output: Contribution to journalArticle

Zinc Oxide
Cryopreservation
Nanoparticles
Spermatozoa
Fluorescence microscopy
22 Citations (Scopus)

Survey of fertility preservation options available to patients with cancer around the globe

Rashedi, A. S., De Roo, S. F., Ataman, L. M., Edmonds, M. E., Silva, A. A., Scarella, A., Horbaczewska, A., Anazodo, A., Arvas, A., De Carvalho, B. R., Sartorio, C., Beerendonk, C. C. M., Diaz-Garcia, C., Suh, C. S., Melo, C., Andersen, C. Y., Motta, E., Greenblatt, E. M., Van Moer, E., Zand, E. & 43 others, Reis, F. M., Sánchez, F., Terrado, G., Rodrigues, J. K., De Meneses e Silva, J. M., Smitz, J., Medrano, J., Lee, J. R., Winkler-Crepaz, K., Smith, K., Melo e Silva, L. H. F., Wildt, L., Salama, M., Del Mar Andrés, M., Bourlon, M. T., Vega, M., Chehin, M. B., De Vos, M., Khrouf, M., Suzuki, N., Azmy, O., Fontoura, P., Campos-Junior, P. H. A., Mallmann, P., Azambuja, R., Marinho, R. M., Anderson, R. A., Jach, R., Antunes, R. A., Mitchell, R., Fathi, R., Adiga, S. K., Takae, S., Kim, S. H., Romero, S., Grieco, S. C., Shaulov, T., Furui, T., Almeida-Santos, T., Nelen, W., Jayasinghe, Y., Sugishita, Y. & Woodruff, T. K., 01-03-2018, In : Journal of global oncology. 2018, 4

Research output: Contribution to journalArticle

Fertility Preservation
Neoplasms
Quality of Health Care
Practice Guidelines
Fertility