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• Article

  PEGylation of superparamagnetic iron oxide nanoparticle for drug delivery applications with decreased toxicity: an in vivo study

  Prabhu, S., Mutalik, S., Rai, S., Udupa, N. & Rao, B. S. S., 01-10-2015, In: Journal of Nanoparticle Research. 17, 10, 412.

  Research output: Contribution to journal › Article › peer-review

  • Drug Delivery
  • Nanoparticles
  • Oxides
  • Drug delivery
  • Iron
  15 Citations (Scopus)

• Peptide dendrimer-conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery

  Hegde, A. R., Rewatkar, P. V., Manikkath, J., Tupally, K., Parekh, H. S. & Mutalik, S., 01-05-2017, In: European Journal of Pharmaceutical Sciences. 102, p. 237-249 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendrimers
  • Ketoprofen
  • Iontophoresis
  • Peptides
  • Skin
  23 Citations (Scopus)

• Polymethacrylate coated valsartan tablets for ileo-colonic delivery: Formulation development and in vitro and in vivo evaluations

  Nayak, U. Y., Mutalik, S. & Nayak, Y., 2013, In: Research Journal of Pharmacy and Technology. 6, 12, p. 1362-1369 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Preclinical pharmacokinetics and biodistribution studies of asenapine maleate using novel and sensitive RP-HPLC method

  Managuli, R. S., Gourishetti, K., Shenoy, R. R., Koteshwara, K. B., Reddy, M. S. & Mutalik, S., 01-07-2017, In: Bioanalysis. 9, 14, p. 1037-1047 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asenapine
  • Pharmacokinetics
  • High Pressure Liquid Chromatography
  • Tissue
  • Liquid-Liquid Extraction
  4 Citations (Scopus)

• Preparation, characterization and pharmacokinetic study of nelfinavir nanocrystals for oral bioavailability enhancement

  Naresh, D. N., Nayak, U. Y., Musmade, P., Mutalik, S. & Nayak, Y., 2015, In: Current Nanoscience. 11, 3, p. 379-387 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Biological Availability
  • Nelfinavir
  • Nanocrystals
  • Pharmacokinetics
  • Nanoparticles
  2 Citations (Scopus)

• Preparation of gold nanoparticles by novel bacterial exopolysaccharide for antibiotic delivery

  Pradeepa, Vidya, S. M., Mutalik, S., Udaya Bhat, K., Huilgol, P. & Avadhani, K., 15-05-2016, In: Life Sciences. 153, p. 171-179 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Gold nanoparticles
  • Nanostructures
  • Assays
  • Bacteria
  • Gold
  23 Citations (Scopus)

• Quinoline Derivative Enhances Human Sperm Motility and Improves the Functional Competence

  Kumari, S., Salian, S. R., Rao, A., Somagond, S. M., Kamble, R. R., Nesaragi, A., Das, J., Rajanikant, G. K., Mutalik, S., Raghu, S. V., Adiga, S. K. & Kalthur, G., 2020, (Accepted/In press) In: Reproductive Sciences.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • quinoline
  • Sperm Motility
  • Mental Competency
  • Spermatozoa
  • Blastocyst

• Skin Delivery of EGCG and Silibinin: Potential of Peptide Dendrimers for Enhanced Skin Permeation and Deposition

  Shetty, P. K., Manikkath, J., Tupally, K., Kokil, G., Hegde, A. R., Raut, S. Y., Parekh, H. S. & Mutalik, S., 01-08-2017, In: AAPS PharmSciTech. 18, 6, p. 2346-2357 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Silybin
  • Dendrimers
  • epigallocatechin gallate
  • Peptides
  • Skin
  19 Citations (Scopus)

• Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

  Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In: Drug Delivery. 24, 1, p. 61-74 14 p.

  Research output: Contribution to journal › Article › peer-review

  • epigallocatechin gallate
  • Hyaluronic Acid
  • Ultraviolet Rays
  • Antioxidants
  • Skin
  62 Citations (Scopus)

• Skin permeation of gemcitabine hydrochloride by passive diffusion, iontophoresis and sonophoresis: In vitro and in vivo evaluations

  Baji, S., Hegde, A. R., Kulkarni, M., Raut, S. Y., Manikkath, J., Reddy, M. S. & Mutalik, S., 01-10-2018, In: Journal of Drug Delivery Science and Technology. 47, p. 49-54 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Iontophoresis
  • gemcitabine
  • Skin
  • In Vitro Techniques
  • HEPES
  5 Citations (Scopus)

• Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract

  Nayak, G., Vadinkar, A., Nair, S., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Shetty, M. M., Kalthur, G. & Adiga, S. K., 01-03-2016, In: Andrologia. 48, 2, p. 125-136 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Moringa oleifera
  • Cyclophosphamide
  • Spermatozoa
  • Injections
  • DNA Damage
  25 Citations (Scopus)

• Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

  Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-12-2017, In: Zygote. p. 1-14 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Haploidy
  • Spermatozoa
  • Oocytes
  • In Vitro Techniques
  • strontium chloride
  1 Citation (Scopus)

• Strategic design of dicer substrate siRNA to mitigate the resistance mediated by ABCC1 in doxorubicinresistant breast cancer

  Gatta, A. K., Chandrashekhar, R., Udupa, N., Reddy, M. S., Mutalik, S. & Josyula, V. R., 04-2020, In: Indian Journal of Pharmaceutical Sciences. 82, 2, p. 329-340 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Doxorubicin
  • Nanoparticles
  • Small Interfering RNA
  • Folic Acid
  • RNA

• Subacute Toxicity Profile of Lacidipine Nanoformulation in Wistar Rats

  Shirodkar, R., Misra, C., Gh, C., Shetty, P., Attari, Z., Mutalik, S. & Lewis, S., 2015, In: Scientific World Journal. 2015

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Subacute toxicity study of lacidipine nanoformulation

  Shirodkar, R., Reddy, N., Kumar, N., Ramalingayya, G., Mutalik, S. & Lewis, S., 26-09-2015, In: Latin American Journal of Pharmacy. 34, 8, p. 1526-1533 8 p.

  Research output: Contribution to journal › Article › peer-review

  • lacidipine
  • Nanoparticles
  • Lipids
  • Body Weight
  • Drug Compounding
  2 Citations (Scopus)

• Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

  Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In: Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

  Research output: Contribution to journal › Article › peer-review

  • naringenin
  • Sunscreening Agents
  • Nanoparticles
  • In Vitro Techniques
  • Skin
  11 Citations (Scopus)

• Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

  Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In: Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

  Research output: Contribution to journal › Article › peer-review

  • ZnO nanoparticles
  • Zinc Oxide
  • Cryopreservation
  • Spermatozoa
  • Nanoparticles
  21 Citations (Scopus)

• Surface engineered nanoliposomal platform for selective lymphatic uptake of asenapine maleate: In vitro and in vivo studies

  Managuli, R. S., Wang, J. T. W., Faruqu, F. M., Pandey, A., Jain, S., Al-Jamal, K. T. & Mutalik, S., 04-2020, In: Materials Science and Engineering C. 109, 110620.

  Research output: Contribution to journal › Article › peer-review

  • Asenapine
  • maleates
  • Liposomes
  • drugs
  • platforms
  6 Citations (Scopus)

• Surface-engineered nanoliposomes with lipidated and non-lipidated peptide-dendrimeric scaffold for efficient transdermal delivery of a therapeutic agent: Development, characterization, toxicological and preclinical performance analyses

  Manikkath, J., Parekh, H. S. & Mutalik, S., 11-2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 156, p. 97-113 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Asenapine
  • Dendrimers
  • Toxicology
  • Peptides
  • Liposomes

• Synthesis, spectral characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff bases derived from 3-formyl quinoline and 2,6-diaminopyridine and their biological studies

  [Unknown], N., Dhumwad, S. D., Mutalik, S., Hugar, M. H. & Naik, P. N., 2013, In: Main Group Chemistry. 12, 1, p. 87-104 18 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Transdermal delivery of lercanidipine hydrochloride: Effect of chemical enhancers and ultrasound

  Shetty, P. K., Suthar, N. A., Menon, J., Deshpande, P. B., Avadhani, K., Kulkarni, R. V. & Mutalik, S., 2013, In: Current Drug Delivery. 10, 4, p. 427-434 8 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Viscosity and thermal conductivity of ZnO–water-based nanofluids stabilized by grafted SMA-g-MPEG comb-shaped copolymer for heat transfer applications

  Pavithra, K. S., Yashoda, M. P., Prasannakumar, S. & Mutalik, S., 01-02-2020, In: Iranian Polymer Journal (English Edition). 29, 2, p. 185-196 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Maleic Anhydrides
  • Styrene
  • Maleic anhydride
  • Polyethylene glycols
  • Copolymers
  2 Citations (Scopus)
• Chapter

  Complex injectables: Development, delivery, and advancement. Development, delivery, and advancement

  Pandey, A., Singh, D., Dhas, N., Tewari, A. K., Pathak, K., Chatap, V., Rathore, K. S. & Mutalik, S., 04-02-2020, Delivery of Drugs: Volume 2: Expectations and Realities of Multifunctional Drug Delivery Systems. Elsevier Inc., p. 191-213 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Equipment and Supplies
  • Injections
  • Dosage Forms
  • Drug Combinations
  • Peptides

• Peptide Dendrimers in Delivery of Bioactive Molecules to Skin

  Manikkath, J., Hegde, A. R., Parekh, H. S. & Mutalik, S., 25-08-2016, Nanoscience in Dermatology. Elsevier Inc., p. 89-97 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Dendrimers
  • Peptides
  • Skin
  • Pharmaceutical Preparations
  • Solid-Phase Synthesis Techniques
  4 Citations (Scopus)
• Comment/debate

  Correction to: Once-daily sustained-release matrix tablets of nicorandil: Formulation and in vitro evaluation (AAPS PharmSciTech, (2003), 4, 4, (480-488), 10.1208/pt040461)

  Kasu, R. R. R., Mutalik, S. & Reddy, S., 01-07-2020, In: AAPS PharmSciTech. 21, 5, 197.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Nicorandil
  • Names
  • Tablets
  • In Vitro Techniques
  1 Citation (Scopus)
• Review article

  An overview of novel and controlled drug delivery systems

  Nayak, U. Y., Mutalik, S. & Udupa, N., 01-05-2016, In: Indian Drugs. 53, 5, p. 5-12 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Drug Delivery Systems
  • Pharmaceutical Preparations
  • Dosage Forms
  • Life Cycle Stages
  • Biological Availability

• Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

  Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Factors
  • Biological Products
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Drug Compounding
  2 Citations (Scopus)

• Copper sulphide based heterogeneous nanoplatforms for multimodal therapy and imaging of cancer: Recent advances and toxicological perspectives

  Nikam, A. N., Pandey, A., Fernandes, G., Kulkarni, S., Mutalik, S. P., Padya, B. S., George, S. D. & Mutalik, S., 15-09-2020, In: Coordination Chemistry Reviews. 419, 213356.

  Research output: Contribution to journal › Review article › peer-review

  • copper sulfides
  • Sulfides
  • Nanostructures
  • Copper
  • therapy

• Delving deeper into dermal and transdermal drug delivery: Factors and mechanisms associated with nanocarrier-mediated strategies

  Manikkath, J., Sumathy, T. K., Manikkath, A. & Mutalik, S., 01-01-2018, In: Current Pharmaceutical Design. 24, 27, p. 3210-3222 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Skin
  • Pharmaceutical Preparations
  • Materials Science
  • Drug Administration Routes
  • Drug Carriers
  6 Citations (Scopus)

• Emerging era of “somes”: polymersomes as versatile drug delivery carrier for cancer diagnostics and therapy

  Sharma, A. K., Prasher, P., Aljabali, A. A., Mishra, V., Gandhi, H., Kumar, S., Mutalik, S., Chellappan, D. K., Tambuwala, M. M., Dua, K. & Kapoor, D. N., 01-10-2020, In: Drug Delivery and Translational Research.

  Research output: Contribution to journal › Review article › peer-review

  • Drug Carriers
  • Molecular Weight
  • Neoplasms
  • Pharmaceutical Preparations
  • Liposomes
  2 Citations (Scopus)

• Factors affecting the morphology of some organic and inorganic nanostructures for drug delivery: characterization, modifications, and toxicological perspectives

  Raychaudhuri, R., Pandey, A., Hegde, A., Abdul Fayaz, S. M., Chellappan, D. K., Dua, K. & Mutalik, S., 2020, In: Expert Opinion on Drug Delivery.

  Research output: Contribution to journal › Review article › peer-review

  • Nanostructures
  • Surface-Active Agents
  • Toxicology
  • Pharmaceutical Preparations
  • Micelles
  1 Citation (Scopus)

• Herbal penetration enhancers and terpenes: An overview

  Kumar, S., Nayak, U. Y., Mutalik, S. & Udupa, N., 01-01-2015, In: Indian Drugs. 52, 1, p. 5-12 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Terpenes
  • Skin
  • Pharmaceutical Preparations
  • laurocapram
  • Drug Administration Routes

• Heterogeneous surface architectured metal-organic frameworks for cancer therapy, imaging, and biosensing: A state-of-the-art review

  Pandey, A., Dhas, N., Deshmukh, P., Caro, C., Patil, P., Luisa García-Martín, M., Padya, B., Nikam, A., Mehta, T. & Mutalik, S., 01-05-2020, In: Coordination Chemistry Reviews. 409, 213212.

  Research output: Contribution to journal › Review article › peer-review

  • Metal-Organic Frameworks
  • metal surfaces
  • therapy
  • cancer
  • Imaging techniques
  15 Citations (Scopus)

• Heterogeneous surface-modified nanoplatforms for the targeted therapy of haematological malignancies

  Kulkarni, S., Pandey, A. & Mutalik, S., 01-01-2020, In: Drug Discovery Today.

  Research output: Contribution to journal › Review article › peer-review

  • Hematologic Neoplasms
  • Peptide Nucleic Acids
  • Phototherapy
  • Golgi Apparatus
  • Complementary Therapies
  2 Citations (Scopus)

• Liquid metal based theranostic nanoplatforms: Application in cancer therapy, imaging and biosensing

  Kulkarni, S., Pandey, A. & Mutalik, S., 06-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 26, 102175.

  Research output: Contribution to journal › Review article › peer-review

  • Gallium
  • Theranostic Nanomedicine
  • Liquid metals
  • Metals
  • Imaging techniques
  4 Citations (Scopus)

• Nanoarchitectronics: A versatile tool for deciphering nanoparticle interaction with cellular proteins, nucleic acids and phospholipids at biological interfaces

  Mutalik, S. P., Pandey, A. & Mutalik, S., 15-05-2020, In: International Journal of Biological Macromolecules. 151, p. 136-158 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • Phospholipids
  • Nanoparticles
  • Nucleic acids
  • Nanotechnology
  • Nucleic Acids
  1 Citation (Scopus)

• Neuroprotection: A versatile approach to combat glaucoma

  Naik, S., Pandey, A., Lewis, S. A., Rao, B. S. S. & Mutalik, S., 15-08-2020, In: European Journal of Pharmacology. 881, 173208.

  Research output: Contribution to journal › Review article › peer-review

  • Neuroprotection
  • Glaucoma
  • Ocular Vision
  • Retinal Diseases
  • Neurons
  2 Citations (Scopus)

• Novel oral drug delivery systems for steroids: Overview and recent updates

  Ganapa, M. S., Mhatre, S. S., Raut, S. Y., Pandey, A., Kalthur, G. & Mutalik, S., 01-07-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 3, p. 541-549 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Drug Delivery Systems
  • Steroids
  • Nanoparticles
  • Microspheres
  • Liposomes

• Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

  Pandey, A., Nikam, A. N., Shreya, A. B., Mutalik, S. P., Gopalan, D., Kulkarni, S., Padya, B. S., Fernandes, G., Mutalik, S. & Prassl, R., 01-09-2020, In: Life Sciences. 256, 117883.

  Research output: Contribution to journal › Review article › peer-review

  • SARS Virus
  • Drug Repositioning
  • Clinical Trials
  • Vaccines
  • Metal ions
  17 Citations (Scopus)

• Pullulan based stimuli responsive and sub cellular targeted nanoplatforms for biomedical application: Synthesis, nanoformulations and toxicological perspective

  Raychaudhuri, R., Naik, S., Shreya, A. B., Kandpal, N., Pandey, A., Kalthur, G. & Mutalik, S., 15-10-2020, In: International Journal of Biological Macromolecules. 161, p. 1189-1205 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • pullulan
  • Toxicology
  • Nanoparticles
  • Lipids
  • Therapy
  2 Citations (Scopus)

• Recent Advancement in Bio-precursor derived graphene quantum dots: Synthesis, Characterization and Toxicological Perspective

  Tade, R. S., Nangare, S. N., Patil, A. G., Pandey, A., Deshmukh, P. K., Patil, D. R., Agrawal, T. N., Mutalik, S., Patil, A. M., More, M. P., Bari, S. B. & Patil, P. O., 28-04-2020, In: Nanotechnology. 31, 29, 292001.

  Research output: Contribution to journal › Review article › peer-review

  • Semiconductor quantum dots
  • Graphite
  • Graphene
  • Industrial Waste
  • Electronic properties
  3 Citations (Scopus)

• Receptor specific, stimuli responsive and subcellular targeted approaches for effective therapy of Alzheimer: Role of surface engineered nanocarriers

  Gopalan, D., Pandey, A., Udupa, N. & Mutalik, S., 10-03-2020, In: Journal of Controlled Release. 319, p. 183-200 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Nanotechnology
  • Alzheimer Disease
  • Peptide Aptamers
  • Quantum Dots
  • Biomimetics
  3 Citations (Scopus)

• Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review

  Das, S., K.R., A., Birangal, S. R., Nikam, A. N., Pandey, A., Mutalik, S. & Joseph, A., 01-10-2020, In: Life Sciences. 258, 118202.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Medical problems
  • Comorbidity
  • Coronavirus Infections
  3 Citations (Scopus)

• Stimuli-responsive and cellular targeted nanoplatforms for multimodal therapy of skin cancer

  Padya, B. S., Pandey, A., Pisay, M., Koteshwara, K. B., Chandrashekhar Hariharapura, R., Bhat, K. U., Biswas, S. & Mutalik, S., 2020, (Accepted/In press) In: European Journal of Pharmacology. 173633.

  Research output: Contribution to journal › Review article › peer-review

  • Skin Neoplasms
  • Therapeutics
  • Nanoparticles
  • Pharmacokinetics
  • Temperature

• Surface engineered bimetallic nanoparticles based therapeutic and imaging platform: recent advancements and future perspective

  Kotha, R., Fernandes, G., Nikam, A. N., Kulkarni, S., Pandey, A., Pandey, S. & Mutalik, S., 01-11-2020, In: Materials Science and Technology (United Kingdom).

  Research output: Contribution to journal › Review article › peer-review

  • Nanoparticles
  • platforms
  • Imaging techniques
  • nanoparticles
  • Chemical properties

• Targeting the intestinal lymphatic system: a versatile path for enhanced oral bioavailability of drugs

  Managuli, R. S., Raut, S. Y., Reddy, M. S. & Mutalik, S., 03-08-2018, In: Expert Opinion on Drug Delivery. 15, 8, p. 787-804 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lymphatic System
  • Biological Availability
  • Nanoparticles
  • Peyer's Patches
  • Pharmaceutical Preparations
  19 Citations (Scopus)