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Author

  • Guruprasad Kalthur
2020

Antidiabetic drug metformin affects the developmental competence of cleavage-stage embryos

Nayak, G., Salian, S. R., Agarwal, P., Suresh Poojary, P., Rao, A., Kumari, S., Kalthur, S. G., Shreya, A. B., Mutalik, S., Adiga, S. K. & Kalthur, G., 01-01-2020, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journal › Article

Early prepubertal cyclophosphamide exposure in mice results in long-term loss of ovarian reserve, and impaired embryonic development and blastocyst quality

Salian, S. R., Uppangala, S., Cheredath, A., D'Souza, F., Kalthur, G., Nayak, V. C., Anderson, R. A. & Adiga, S. K., 2020, In : PLoS One. 15, 6, p. e0235140

Research output: Contribution to journal › Article

Open Access

Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress

Hegde, S., Poojary, K. K., Rasquinha, R., Crasta, D. N., Gopalan, D., Mutalik, S., Siddiqui, S., Adiga, S. K. & Kalthur, G., 01-01-2020, (Accepted/In press) In : Pesticide Biochemistry and Physiology. 104588.

Research output: Contribution to journal › Article

Ethanolic extract of Moringa oleifera leaves alleviate cyclophosphamide-induced testicular toxicity by improving endocrine function and modulating cell specific gene expression in mouse testis

Nayak, G., Rao, A., Mullick, P., Mutalik, S., Kalthur, S. G., Adiga, S. K. & Kalthur, G., 15-09-2020, In : Journal of Ethnopharmacology. 259, 112922.

Research output: Contribution to journal › Article

Exposure to first line anti-tuberculosis drugs in prepubertal age reduces the quality and functional competence of spermatozoa and oocytes in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Kalthur, S. G., Mutalik, S. P., Mutalik, S., Adiga, S. K. & Kalthur, G., 01-2020, In : Environmental Toxicology and Pharmacology. 73, 103292.

Research output: Contribution to journal › Article

Germinal stage vitrification is superior to MII stage vitrification in prepubertal mouse oocytes

Daddangadi, A., Uppangala, S., Kalthur, G., Talevi, R. & Adiga, S. K., 01-01-2020, (Accepted/In press) In : Cryobiology.

Research output: Contribution to journal › Article

Naringin nano-ethosomal novel sunscreen creams: Development and performance evaluation

Gollavilli, H., Hegde, A. R., Managuli, R. S., Bhaskar, K. V., Dengale, S. J., Reddy, M. S., Kalthur, G. & Mutalik, S., 09-2020, In : Colloids and Surfaces B: Biointerfaces. 193, 111122.

Research output: Contribution to journal › Article

Pullulan based stimuli responsive and sub cellular targeted nanoplatforms for biomedical application: Synthesis, nanoformulations and toxicological perspective

Raychaudhuri, R., Naik, S., Shreya, A. B., Kandpal, N., Pandey, A., Kalthur, G. & Mutalik, S., 15-10-2020, In : International Journal of Biological Macromolecules. 161, p. 1189-1205 17 p.

Research output: Contribution to journal › Review article

Reduced ovarian response to controlled ovarian stimulation is associated with increased oxidative stress in the follicular environment

Uppangala, S., Fernandes, G., Salian, S. R., Kumar, P., Talevi, R., Kalthur, G. & Adiga, S. K., 01-01-2020, (Accepted/In press) In : Reproductive biology.

Research output: Contribution to journal › Article

2019

Cyclodextrins as Carriers in Targeted Delivery of Therapeutic Agents: Focused Review on Traditional and Inimitable Applications

Raut, S. Y., Manne, A. S. N., Kalthur, G., Jain, S. & Mutalik, S., 01-01-2019, In : Current Pharmaceutical Design. 25, 4, p. 444-454 11 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Nanocomposite clay-polymer microbeads for oral controlled drug delivery: Development and, in vitro and in vivo evaluations

Raut, S. Y., Gahane, A., Joshi, M. B., Kalthur, G. & Mutalik, S., 01-06-2019, In : Journal of Drug Delivery Science and Technology. 51, p. 234-243 10 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Sperm-mediated DNA lesions alter metabolite levels in spent embryo culture medium

Souza, F. D., Asampille, G., Uppangala, S., Kalthur, G., Atreya, H. S. & Adiga, S. K., 01-01-2019, In : Reproduction, Fertility and Development. 31, 3, p. 443-450 8 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development

Salian, S. R., Nayak, G., Kumari, S., Patel, S., Gowda, S., Shenoy, Y., Sugunan, S., G.K, R., Managuli, R. S., Mutalik, S., Dahiya, V., Pal, S., Adiga, S. K. & Kalthur, G., 15-02-2019, In : Journal of Assisted Reproduction and Genetics. 36, 2, p. 255-266 12 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)
2018

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

D’Souza, F., Uppangala, S., Asampille, G., Salian, S. R., Kalthur, G., Talevi, R., Atreya, H. S. & Adiga, S. K., 01-12-2018, In : Scientific Reports. 8, 1, 17025.

Research output: Contribution to journal › Article

4 Citations (Scopus)

Sunscreen creams containing naringenin nanoparticles: Formulation development and in vitro and in vivo evaluations

Joshi, H., Hegde, A. R., Shetty, P. K., Gollavilli, H., Managuli, R. S., Kalthur, G. & Mutalik, S., 01-01-2018, In : Photodermatology Photoimmunology and Photomedicine. 34, 1, p. 69-81 13 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)
2017

Epigenetic changes in preimplantation embryos subjected to laser manipulation

Honguntikar, S. D., Salian, S. R., D’Souza, F., Uppangala, S., Kalthur, G. & Adiga, S. K., 01-12-2017, In : Lasers in Medical Science. 32, 9, p. 2081-2087 7 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Haploid parthenotes express differential response to in vitro exposure of ammonia compared to normally fertilized embryos

Nair, R., Mutalik, S., Dasappa, J. P., Kalthur, G. & Adiga, S. K., 22-04-2017, In : Biochemical and Biophysical Research Communications. 486, 1, p. 88-93 6 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Indian propolis ameliorates the mitomycin C-induced testicular toxicity by reducing DNA damage and elevating the antioxidant activity

Kumari, S., Nayak, G., Lukose, S. T., Kalthur, S. G., Bhat, N., Hegde, A. R., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-11-2017, In : Biomedicine and Pharmacotherapy. 95, p. 252-263 12 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen

Manikkath, J., Hegde, A. R., Kalthur, G., Parekh, H. S. & Mutalik, S., 15-04-2017, In : International Journal of Pharmaceutics. 521, 1-2, p. 110-119 10 p.

Research output: Contribution to journal › Article

27 Citations (Scopus)

Liposome-encapsulated diacyl glycerol and inositol triphosphate-induced delayed oocyte activation and poor development of parthenotes

Nair, R., Manikkath, J., Hegde, A. R., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-09-2017, In : Journal of the Turkish German Gynecology Association. 18, 3, p. 102-109 8 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage

Avadhani, K. S., Manikkath, J., Tiwari, M., Chandrasekhar, M., Godavarthi, A., Vidya, S. M., Hariharapura, R. C., Kalthur, G., Udupa, N. & Mutalik, S., 03-02-2017, In : Drug Delivery. 24, 1, p. 61-74 14 p.

Research output: Contribution to journal › Article

42 Citations (Scopus)

Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes

Nair, R., Aboobacker, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 28-11-2017, (Accepted/In press) In : Zygote. p. 1-14 14 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa

Isaac, A. V., Kumari, S., Nair, R., Urs, D. R., Salian, S. R., Kalthur, G., Adiga, S. K., Manikkath, J., Mutalik, S., Sachdev, D. & Pasricha, R., 16-12-2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 656-662 7 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)
2016

Anatomy and development of the male reproductive system

Kalthur, S. G. & Kalthur, G., 01-01-2016, Male Infertility: A Clinical Approach. Springer India, p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Corrigendum to "Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells" [Mutat. Res.-Genet. Toxicol. Environ. Mutagen. (2015) 86-95] DOI: 10.1016/j.mrgentox.2015.06.004

Khaw, A. K., Sameni, S., Venkatesan, S., Kalthur, G. & Hande, M. P., 01-03-2016, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 798-799, p. 55-56 2 p.

Research output: Contribution to journal › Comment/debate

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

Mutalik, S., Suthar, N. A., Managuli, R. S., Shetty, P. K., Avadhani, K., Kalthur, G., Kulkarni, R. V. & Thomas, R., 01-05-2016, In : International Journal of Biological Macromolecules. 86, p. 709-720 12 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (Oct4) expression and developmental potential of oocytes following multiple superovulation

Kalthur, G., Salian, S. R., Nair, R., Mathew, J., Adiga, S. K., Kalthur, S. G., Zeegers, D. & Hande, M. P., 2016, In : Reproduction, Fertility and Development. 28, 12, p. 2027-2038 12 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Ethambutol induces testicular damage and decreases the sperm functional competence in Swiss albino mice

Rao, A., Nayak, G., Kumari, S., Prabhu, A. D., Khandige, N., Kalthur, S. G., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Environmental Toxicology and Pharmacology. 47, p. 28-37 10 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Ethanolic extract of Moringa oleifera Lam. leaves protect the pre-pubertal spermatogonial cells from cyclophosphamide-induced damage

Nayak, G., Honguntikar, S. D., Kalthur, S. G., D'Souza, A. S., Mutalik, S., Setty, M. M., Kalyankumar, R., Krishnamurthy, H., Kalthur, G. & Adiga, S. K., 22-04-2016, In : Journal of Ethnopharmacology. 182, p. 101-109 9 p.

Research output: Contribution to journal › Article

14 Citations (Scopus)

Fertility preservation in men and prepubertal boys

Uppangala, S., Kalthur, G. & Adiga, S. K., 01-01-2016, Male Infertility: A Clinical Approach. Springer India, p. 221-230 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Genetic Instability in Lymphocytes is Associated with Blood Plasma Antioxidant Levels in Health Care Workers Occupationally Exposed to Ionizing Radiation

Kumar, D., Kumari, S., Salian, S. R., Uppangala, S., Kalthur, G., Challapalli, S., Chandraguthi, S. G., Kumar, P. & Adiga, S. K., 2016, In : International Journal of Toxicology. 35, 3, p. 327-335 9 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Influence of sperm DNA damage on human preimplantation embryo metabolism

Uppangala, S., Pudakalakatti, S., D'souza, F., Salian, S. R., Kalthur, G., Kumar, P., Atreya, H. & Adiga, S. K., 01-09-2016, In : Reproductive biology. 16, 3, p. 234-241 8 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

Laser assisted zona hatching does not lead to immediate impairment in human embryo quality and metabolism

Uppangala, S., D’Souza, F., Pudakalakatti, S., Atreya, H. S., Raval, K., Kalthur, G. & Adiga, S. K., 01-11-2016, In : Systems Biology in Reproductive Medicine. 62, 6, p. 396-403 8 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Mitigating effect of Indian propolis against mitomycin C induced bone marrow toxicity

Kumari, S., Naik, P., Vishma, B. L., Salian, S. R., Devkar, R. A., Khan, S., Mutalik, S., Kalthur, G. & Adiga, S. K., 01-10-2016, In : Cytotechnology. 68, 5, p. 1789-1800 12 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Nano-transfersomal formulations for transdermal delivery of asenapine maleate: in vitro and in vivo performance evaluations

Shreya, A. B., Managuli, R. S., Menon, J., Kondapalli, L., Hegde, A. R., Avadhani, K., Shetty, P. K., Amirthalingam, M., Kalthur, G. & Mutalik, S., 02-07-2016, In : Journal of Liposome Research. 26, 3, p. 221-232 12 p.

Research output: Contribution to journal › Article

24 Citations (Scopus)

Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract

Nayak, G., Vadinkar, A., Nair, S., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Shetty, M. M., Kalthur, G. & Adiga, S. K., 01-03-2016, In : Andrologia. 48, 2, p. 125-136 12 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Sperm chromatin immaturity observed in short abstinence ejaculates affects DNA integrity and longevity in vitro

Uppangala, S., Mathai, S. E., Salian, S. R., Kumar, D., Singh, V. J., D'Souza, F., Kalthur, G., Kamath, A. & Adiga, S. K., 01-04-2016, In : PLoS One. 11, 4, e0152942.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Sperm DNA damage: Causes and laboratory detection

Adiga, S. K. & Kalthur, G., 01-01-2016, Male Infertility: A Clinical Approach. Springer India, p. 155-165 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Synthesis, anti-proliferative and genotoxicity studies of 6-chloro-5-(2-substituted-ethyl)-1,3-dihydro-2 H-indol-2-ones and 6-chloro-5-(2-chloroethyl)-3-(alkyl/ary-2-ylidene)indolin-2-ones

Meti, G. Y., Kamble, A. A., Kamble, R. R., Somagond, S. M., Devarajegowda, H. C., Kumari, S., Kalthur, G. & Adiga, S. K., 04-10-2016, In : European Journal of Medicinal Chemistry. 121, p. 221-231 11 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Unraveling the association between genetic integrity and metabolic activity in pre-implantation stage embryos

D'Souza, F., Pudakalakatti, S. M., Uppangala, S., Honguntikar, S., Salian, S. R., Kalthur, G., Pasricha, R., Appajigowda, D., Atreya, H. S. & Adiga, S. K., 17-11-2016, In : Scientific Reports. 6, 37291.

Research output: Contribution to journal › Article

8 Citations (Scopus)
2015

Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In : International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

Research output: Contribution to journal › Article

31 Citations (Scopus)

In situ viability detection assays induce heat-shock protein 70 expression in spermatozoa without affecting the chromatin integrity

Asokan, Y., Honguntikar, S. D., Uppangala, S., Salian, S. R., Kumar, D., Kalthur, G. & Adiga, S. K., 01-10-2015, In : Andrologia. 47, 8, p. 958-965 8 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

In vitro matured oocytes are more susceptible than in vivo matured oocytes to mock ICSI induced functional and genetic changes

Uppangala, S., Dhiman, S., Salian, S. R., Singh, V. J., Kalthur, G. & Adiga, S. K., 18-03-2015, In : PLoS One. 10, 3, e0119735.

Research output: Contribution to journal › Article

4 Citations (Scopus)

Oocytes recovered after ovarian tissue slow freezing have impaired H2AX phosphorylation and functional competence

Sudhakaran, S., Uppangala, S., Salian, S. R., Honguntikar, S. D., Nair, R., Kalthur, G. & Adiga, S. K., 2015, In : Reproduction, Fertility and Development. 27, 8, p. 1242-1248 7 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells

Khaw, A. K., Sameni, S., Venkatesan, S., Kalthur, G. & Hande, M. P., 01-11-2015, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 793, p. 86-95 10 p.

Research output: Contribution to journal › Article

22 Citations (Scopus)
2014

Association between sperm DNA integrity and seminal plasma antioxidant levels in health workers occupationally exposed to ionizing radiation

Kumar, D., Salian, S. R., Kalthur, G., Uppangala, S., Kumari, S., Challapalli, S., Chandraguthi, S. G., Jain, N., Krishnamurthy, H., Kumar, P. & Adiga, S. K., 2014, In : Environmental Research. 132, p. 297-304 8 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)

Laser-assisted hatching of cleavage-stage embryos impairs developmental potential and increases DNA damage in blastocysts

Honguntikar, S. D., Uppangala, S., Salian, S. R., Kalthur, G., Kumar, P. & Adiga, S. K., 2014, In : Lasers in Medical Science. 30, 1, p. 95-101 7 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Liposome encapsulated soy lecithin and cholesterol can efficiently replace chicken egg yolk in human semen cryopreservation medium

Mutalik, S., Salian, S. R., Avadhani, K., Menon, J., Joshi, H., Hegde, A. R., Kumar, P., Kalthur, G. & Adiga, S. K., 2014, In : Systems Biology in Reproductive Medicine. 60, 3, p. 183-188 6 p.

Research output: Contribution to journal › Article

13 Citations (Scopus)

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

Nair, R., Singh, V. J., Salian, S. R., Kalthur, S. G., D'Souza, A. S., Shetty, P. K., Mutalik, S., Kalthur, G. & Adiga, S. K., 2014, In : Toxicology and Applied Pharmacology. 279, 3, p. 338-350 13 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Ovarian tissue vitrification is more efficient than slow freezing in protecting oocyte and granulosa cell DNA integrity

Mathias, F. J., D'souza, F., Uppangala, S., Salian, S. R., Kalthur, G. & Adiga, S. K., 01-12-2014, In : Systems Biology in Reproductive Medicine. 60, 6, p. 317-322 6 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)