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• 2020

  Blockchain for Digital Health: Prospects and Challenges

  Evangelatos, N., Özdemir, V. & Brand, A., 01-05-2020, In: OMICS A Journal of Integrative Biology. 24, 5, p. 237-240 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Computer Communication Networks
  • Blockchain
  • Biomedical Research
  • Economics
  • Health

• Digital Transformation and Governance Innovation for Public Biobanks and Free/Libre Open Source Software Using a Blockchain Technology

  Evangelatos, N., Upadya, S. P., Venne, J., Satyamoorthy, K., Brand, H., Ramashesha, C. S. & Brand, A., 01-05-2020, In: OMICS A Journal of Integrative Biology. 24, 5, p. 278-285 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blockchain
  • Open source software
  • Enclosures
  • Software
  • Health
  1 Citation (Scopus)

• International consortium for personalized medicine: An international survey about the future of personalized medicine

  Venne, J., Busshoff, U., Poschadel, S., Menschel, R., Evangelatos, N., Vysyaraju, K. & Brand, A., 03-2020, In: Personalized Medicine. 17, 2, p. 89-100 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Precision Medicine
  • Public Policy
  • Consensus
  • Practice Guidelines
  • Ocular Vision
  3 Citations (Scopus)
• 2019

  Does the electronic health card for asylum seekers lead to an excessive use of the health system? Results of a survey in two municipalities of the German ruhr area

  Jäger, P., Claassen, K., Ott, N. & Brand, A., 01-04-2019, In: International Journal of Environmental Research and Public Health. 16, 7, 1178.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Refugees
  • Health Insurance
  • Health
  • Delivery of Health Care
  • Referral and Consultation
  4 Citations (Scopus)

• Narrative review: The (mental) health consequences of the northern Iraq offensive of ISIS in 2014 for female Yezidis

  Jäger, P., Rammelt, C., Ott, N. & Brand, A., 01-07-2019, In: International Journal of Environmental Research and Public Health. 16, 13, 2435.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Iraq
  • Mental Health
  • Genocide
  • Syria
  • Long-Term Care
  1 Citation (Scopus)

• Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

  Hines, P. A., Guy, R. H., Brand, A., Humphreys, A. J. & Papaluca-Amati, M., 01-01-2019, (Accepted/In press) In: British Journal of Clinical Pharmacology.

  Research output: Contribution to journal › Article › peer-review

  • Interviews
  • Technology
  • Therapeutics
  4 Citations (Scopus)

• Scanning the horizon: A systematic literature review of methodologies

  Hines, P., Hiu Yu, L., Guy, R. H., Brand, A. & Papaluca-Amati, M., 01-05-2019, In: BMJ Open. 9, 5, e026764.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Systematic Reviews
  • Gray Literature
  • Practice Guidelines
  • Uncertainty
  • Decision Making
  5 Citations (Scopus)

• The Creation and Management of Innovations in Healthcare and ICT: The European and African Experience

  Halfmann, S. S. G., Evangelatos, N., Kweyu, E., Devilliers, C., Steinhausen, K., Van Der Merwe, A. & Brand, A., 01-08-2019, In: Public Health Genomics. 21, 5-6, p. 197-206 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Delivery of Health Care
• 2018

  Antibiotics-Induced Obesity: A Mitochondrial Perspective

  Andrade, M. J., Jayaprakash, C., Bhat, S., Evangelatos, N., Brand, A. & Satyamoorthy, K., 01-04-2018, In: Public Health Genomics.

  Research output: Contribution to journal › Article › peer-review

  • Obesity
  • Anti-Bacterial Agents
  • Molecular Biology
  • Genetic Predisposition to Disease
  • Gastrointestinal Microbiome
  5 Citations (Scopus)

• Attitudes towards personal genomics and sharing of genetic data among older swiss adults: A qualitative study

  Mählmann, L., Schee Gen Halfmann, S., Von Wyl, A. & Brand, A., 01-04-2018, In: Public Health Genomics. 20, 5, p. 293-306 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Information Dissemination
  • Genomics
  • Interviews
  • Motivation
  • Computer Security
  4 Citations (Scopus)

• Big Data for Public Health Policy-Making: Policy Empowerment

  Mählmann, L., Reumann, M., Evangelatos, N. & Brand, A., 01-08-2018, In: Public Health Genomics. 20, 6, p. 312-320 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Big Data
  • Policy Making
  • Public Policy
  • Health Policy
  • Power (Psychology)
  4 Citations (Scopus)

• Maternal sepsis in the era of genomic medicine

  Kouskouti, C., Evangelatos, N., Brand, A. & Kainer, F., 01-01-2018, (Accepted/In press) In: Archives of Gynecology and Obstetrics. p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Infectious Pregnancy Complications
  • Medicine
  • Technology
  • Systems Biology
  • Income
  1 Citation (Scopus)

• Metabolomics in sepsis and its impact on public health

  Evangelatos, N., Bauer, P., Reumann, M., Satyamoorthy, K., Lehrach, H. & Brand, A., 01-04-2018, In: Public Health Genomics. 20, 5, p. 274-285 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolomics
  • Sepsis
  • Public Health
  • Technology
  • Metabolome
  9 Citations (Scopus)

• Multi-Omics Research Trends in Sepsis: A Bibliometric, Comparative Analysis between the United States, the European Union 28 Member States, and China

  Evangelatos, N., Satyamoorthy, K., Levidou, G., Bauer, P., Brand, H., Kouskouti, C., Lehrach, H. & Brand, A., 01-03-2018, In: OMICS A Journal of Integrative Biology. 22, 3, p. 190-197 8 p.

  Research output: Contribution to journal › Article › peer-review

  • European Union
  • China
  • Sepsis
  • Genomics
  • Technology
  5 Citations (Scopus)

• Personalized health in a public health perspective

  Evangelatos, N., Satyamoorthy, K. & Brand, A., 01-05-2018, In: International Journal of Public Health. p. 1-2 2 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Potentials and Challenges of the Health Data Cooperative Model

  Van Roessel, I., Reumann, M. & Brand, A., 01-08-2018, In: Public Health Genomics. 20, 6, p. 321-331 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Health
  • Big Data
  • Cloud Computing
  • Computer Security
  • Information Storage and Retrieval
  6 Citations (Scopus)

• The genomic medicine alliance: A global effort to facilitate the introduction of genomics into healthcare in developing nations

  Cooper, D. N., Mitropoulou, C., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Lee, M. T. M., Macek, M., Mitropoulos, K., Al-Mulla, F., Prainsack, B., van Schaik, R. H., Squassina, A., Taruscio, D., Vayena, E., Vozikis, A., Williams, M. S., Ylstra, B. & Patrinos, G. P., 01-01-2018, Genomic Medicine in Emerging Economies: Genomics for Every Nation. Elsevier, p. 173-188 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Genomics
  • Medicine
  • Developing Countries
  • Delivery of Health Care
  • Public health
  1 Citation (Scopus)

• Use of Free/Libre Open Source Software in Sepsis "-Omics" Research: A Bibliometric, Comparative Analysis among the United States, EU-28 Member States, and China

  Evangelatos, N., Satyamourthy, K., Levidou, G., Brand, H., Bauer, P., Kouskouti, C. & Brand, A., 01-05-2018, In: OMICS A Journal of Integrative Biology. 22, 5, p. 365-372 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Open source software
  • China
  • Sepsis
  • Software
  • Systems science
  1 Citation (Scopus)
• 2017

  Challenges for small biopharmaceutical companies

  Evangelatos, N. & Brand, A., 27-04-2017, In: New England Journal of Medicine. 376, 17, 1 p.

  Research output: Contribution to journal › Letter › peer-review

• Epigenomics, Pharmacoepigenomics, and Personalized Medicine in Cervical Cancer

  Kabekkodu, S. P., Chakrabarty, S., Ghosh, S., Brand, A. & Satyamoorthy, K., 01-09-2017, In: Public Health Genomics. 20, 2, p. 100-115 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Precision Medicine
  • Uterine Cervical Neoplasms
  • Epigenomics
  • Histone Code
  • Untranslated RNA
  11 Citations (Scopus)

• European healthcare systems readiness to shift from 'one-size fits all' to personalized medicine

  Schee Genannt Halfmann, S., Evangelatos, N., Schröder-Bäck, P. & Brand, A., 01-01-2017, In: Personalized Medicine. 14, 1, p. 63-74 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Precision Medicine
  • Delivery of Health Care
  • Big Data
  • Health Literacy
  6 Citations (Scopus)

• Personalized medicine: What’s in it for rare diseases?

  Schee Genannt Halfmann, S., Mählmann, L., Leyens, L., Reumann, M. & Brand, A., 01-01-2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 387-404 18 p. (Advances in Experimental Medicine and Biology; vol. 1031).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Precision Medicine
  • Medicine
  • Rare Diseases
  • Big Data
  • Big data
  9 Citations (Scopus)

• Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy

  Vozikis, A., Cooper, D. N., Mitropoulou, C., Kambouris, M. E., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Lee, M. T. M., Leyens, L., Macek, M., Al-Mulla, F., Prainsack, B., Squassina, A., Taruscio, D., Van Schaik, R. H., Vayena, E., Williams, M. S. & Patrinos, G. P., 01-01-2017, In: Public Health Genomics. 19, 6, p. 352-363 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Medicine
  • Costs and Cost Analysis
  • Delivery of Health Care
  • Budgets
  • Cost-Benefit Analysis
  18 Citations (Scopus)

• Use of big data for drug development and for public and personal health and care

  Leyens, L., Reumann, M., Malats, N. & Brand, A., 01-01-2017, In: Genetic Epidemiology. 41, 1, p. 51-60 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Big Data
  • Drug Development
  • Public Health
  • Drug Discovery
  • Delivery of Health Care
  18 Citations (Scopus)
• 2016

  Attitudes towards personal genomics among older Swiss adults: An exploratory study

  Mählmann, L., Röcke, C., Brand, A., Hafen, E. & Vayena, E., 01-03-2016, In: Applied and Translational Genomics. 8, p. 9-15 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Genomics
  • Metagenomics
  • Privacy
  • Switzerland
  • Health
  13 Citations (Scopus)

• Clinical trial data as public goods: Fair trade and the virtual knowledge bank as a solution to the free rider problem - A framework for the promotion of innovation by facilitation of clinical trial data sharing among biopharmaceutical companies in the era of omics and big data

  Evangelatos, N., Reumann, M., Lehrach, H. & Brand, A., 01-08-2016, In: Public Health Genomics. 19, 4, p. 211-219 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Big Data
  • Information Dissemination
  • Biological Products
  • Clinical Trials
  • Industry
  11 Citations (Scopus)

• Early Patient Access to Medicines: Health Technology Assessment Bodies Need to Catch Up with New Marketing Authorization Methods

  Leyens, L. & Brand, A., 01-06-2016, In: Public Health Genomics. 19, 3, p. 187-191 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Biomedical Technology Assessment
  • Marketing
  • Medicine
  • International Agencies
  • United States Food and Drug Administration
  15 Citations (Scopus)

• Perspectives on translational genomics and public health in India

  Chakrabarty, S., Kabekkodu, S. P., Brand, A. & Satyamoorthy, K., 01-04-2016, In: Public Health Genomics. 19, 2, p. 61-68 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Genomics
  • India
  • Public Health
  • Precision Medicine
  • Public Health Practice
  3 Citations (Scopus)

• Public Health Genomics: the essential part for good governance in public health

  Brand, A., Evangelatos, N. & Satyamoorthy, K., 01-05-2016, In: International Journal of Public Health. 61, 4, p. 401-403 3 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Toward the integration of Omics data in epidemiological studies: still a “long and winding road”

  López de Maturana, E., Pineda, S., Brand, A., Van Steen, K. & Malats, N., 01-11-2016, In: Genetic Epidemiology. 40, 7, p. 558-569 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Epidemiologic Studies
  • Risk Assessment
  • Epidemiologists
  • Precision Medicine
  • Primary Prevention
  12 Citations (Scopus)
• 2015

  Available tools to facilitate early patient access to medicines in the EU and the USA: Analysis of conditional approvals and the implications for personalized medicine

  Leyens, L., Richer, É., Melien, Ø., Ballensiefen, W. & Brand, A., 08-10-2015, In: Public Health Genomics. 18, 5, p. 249-259 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine
  • Human Body
  • Consumer Product Safety
  • Phase II Clinical Trials
  • Environmental Exposure
  12 Citations (Scopus)

• Establishing the Evidence Bar for Molecular Diagnostics in Personalised Cancer Care

  Schneider, D., Bianchini, G., Horgan, D., Michiels, S., Witjes, W., Hills, R., Plun-Favreau, J., Brand, A. & Lawler, M., 01-12-2015, In: Public Health Genomics. 18, 6, p. 349-358 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Molecular Pathology
  • Biomarkers
  • Neoplasms
  • Biological Therapy
  • Precision Medicine
  7 Citations (Scopus)

• Getting Personal: Accelerating Personalised and Precision Medicine Integration into Clinical Cancer Research and Care in Clinical Trials

  Horgan, D., Lawler, M. & Brand, A., 01-12-2015, In: Public Health Genomics. 18, 6, p. 325-328 4 p.

  Research output: Contribution to journal › Review article › peer-review
  3 Citations (Scopus)

• Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population

  Fernandes, R. C., Hasan, M., Gupta, H., Geetha, K., Rai, P. S., Hande, M. H., D’Souza, S. C., Adhikari, P., Brand, A. & Satyamoorthy, K., 23-06-2015, In: Molecular Genetics and Genomics. 290, 3, p. 1155-1168 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutathione Transferase
  • Plasmodium vivax
  • Genetic Variation
  • Catalase
  • Superoxide Dismutase
  12 Citations (Scopus)

• Is precision medicine the route to a healthy world?

  Horgan, D., Paradiso, A., McVie, G., Banks, I., Van Der Wal, T., Brand, A. & Lawler, M., 25-07-2015, In: The Lancet. 386, 9991, p. 336-337 2 p.

  Research output: Contribution to journal › Letter › peer-review
  10 Citations (Scopus)

• Success stories in genomic medicine from resource-limited countries

  Mitropoulos, K., Al Jaibeji, H., Forero, D. A., Laissue, P., Wonkam, A., Lopez-Correa, C., Mohamed, Z., Chantratita, W., Lee, M. T. M., Llerena, A., Brand, A., Ali, B. R. & Patrinos, G. P., 2015, In: Human Genomics. 9, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenetics
  • Medicine
  • Public Health Informatics
  • Public Health Practice
  • Genomics
  27 Citations (Scopus)
• 2014

  An index of barriers for the implementation of personalised medicine and pharmacogenomics in Europe

  Horgan, D., Jansen, M., Leyens, L., Lal, J. A., Sudbrak, R., Hackenitz, E., Bußhoff, U., Ballensiefen, W. & Brand, A., 25-12-2014, In: Public Health Genomics. 17, p. 287-298 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenetics
  • Precision Medicine
  • Delivery of Health Care
  • Policy Making
  • Needs Assessment
  44 Citations (Scopus)

• Bridging genomics research between developed and developing countries: The Genomic Medicine Alliance

  Cooper, D. N., Brand, A., Dolzan, V., Fortina, P., Innocenti, F., Michael Lee, M. T., MacEk, M., Al-Mulla, F., Prainsack, B., Squassina, A., Vayena, E., Vozikis, A., Williams, M. S. & Patrinos, G. P., 01-09-2014, In: Personalized Medicine. 11, 7, p. 615-623 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Genomics
  • Developed Countries
  • Developing Countries
  • Medicine
  • Public Health Informatics
  20 Citations (Scopus)

• European data-driven economy: A lighthouse initiative on Personalised Medicine

  Horgan, D., Romão, M., Torbett, R. & Brand, A., 01-12-2014, In: Health Policy and Technology. 3, 4, p. 226-233 8 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Genetic similarities between tobacco use disorder and related comorbidities: An exploratory study

  de Viron, S., Morré, S. A., Van Oyen, H., Brand, A. & Ouburg, S., 24-07-2014, In: BMC Medical Genetics. 15, 1, 85.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco Use Disorder
  • Comorbidity
  • Malignant Hypertension
  • Genes
  • Tobacco Use
  1 Citation (Scopus)

• Genotype-based prevention of psychosis onset and schizophrenia: A personalized approach in a target population

  Taneri, B., Hocaoglu, M. B., Brand, A. & Van Os, J., 2014, In: Personalized Medicine. 11, 2, p. 167-172 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Health Services Needs and Demand
  • Psychotic Disorders
  • Schizophrenia
  • Genotype
  • Gene-Environment Interaction
  1 Citation (Scopus)

• Health data cooperatives - Citizen empowerment

  Hafen, E., Kossmann, D. & Brand, A., 2014, In: Methods of Information in Medicine. 53, 2, p. 82-86 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Power (Psychology)
  • Health
  • Precision Medicine
  • Insurance Benefits
  • Data Aggregation
  69 Citations (Scopus)

• Public health genomics joins forces with the genomic medicine alliance

  Patrinos, G. P. & Brand, A., 2014, In: Public Health Genomics. 17, 3, p. 125-126 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  3 Citations (Scopus)

• RARE-Bestpractices: A platform for sharing best practices for the management of rare diseases

  Taruscio, D., Morciano, C., Laricchiuta, P., Mincarone, P., Palazzo, F., Leo, C. G., Sabina, S., Guarino, R., Auld, J., Sejersen, T., Gavhed, D., Ritchie, K., Hilton-Boon, M., Manson, J., Kanavos, P. G., Tordrup, D., Tzouma, V., Le Cam, Y., Senecat, J., Filippini, G. & 25 others, Minozzi, S., Del Giovane, C., Schünemann, H., Meerpohl, J. J., Prediger, B., Schell, L., Stefanov, R., Iskrov, G., Miteva-Katrandzhieva, T., Serrano-Aguilar, P., Perestelo-Perez, L., Trujillo-Martín, M. M., Pérez-Ramos, J., Rivero-Santana, A., Brand, A., Van Kranen, H., Bushby, K., Atalaia, A., Ramet, J., Siderius, L., Posada, M., Abaitua-Borda, I., Ferreira, V. A., Hens-Pérez, M. & Manzanares, F. J., 11-11-2014, In: Orphanet Journal of Rare Diseases. 9, 1, O14.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Social confounders of vaccine response

  Ling, M. L., Brand, A. & Ambrosino, E., 23-10-2014, Making Global Health Care Innovation Work: Standardization and Localization. Palgrave Macmillan Ltd., p. 140-157 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• The overarching framework of translation and integration into healthcare: A case for the LAL model

  Lal, J. A., Morré, S. A. & Brand, A., 01-2014, In: Personalized Medicine. 11, 1, p. 41-62 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Learning
  • Delivery of Health Care
  • Health Impact Assessment
  • Technology Transfer
  • Biomedical Technology Assessment
  3 Citations (Scopus)

• The translation of nutri-epigenetics into public health policy: The case of folic acid supplementation

  Verhagen, M. M. C., Brand, A. & Ambrosino, E., 23-10-2014, Making Global Health Care Innovation Work: Standardization and Localization. Palgrave Macmillan Ltd., p. 122-138 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Whole genome prediction of bladder cancer risk with the bayesian LASSO

  De Maturana, E. L., Chanok, S. J., Picornell, A. C., Rothman, N., Herranz, J., Calle, M. L., García-Closas, M., Marenne, G., Brand, A., Tardón, A., Carrato, A., Silverman, D. T., Kogevinas, M., Gianola, D., Real, F. X. & Malats, N., 2014, In: Genetic Epidemiology. 38, 5, p. 467-476 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Urinary Bladder Neoplasms
  • Urinary Bladder
  • Genome
  • Carcinoma
  • Aptitude
  9 Citations (Scopus)

• Working towards personalization in medicine: Main obstacles to reaching this vision from today's perspective

  Leyens, L., Horgan, D., Lal, J. A., Steinhausen, K., Satyamoorthy, K. & Brand, A., 01-09-2014, In: Personalized Medicine. 11, 7, p. 641-649 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine
  • Medicine
  • Delivery of Health Care
  • Formal Social Control
  • Direction compound
  9 Citations (Scopus)
• 2013

  Chlamydia trachomatis infections and subfertility: Opportunities to translate host pathogen genomic data into public health

  Lal, J. A., Malogajski, J., Verweij, S. P., De Boer, P., Ambrosino, E., Brand, A., Ouburg, S. & Morré, S. A., 03-2013, In: Public Health Genomics. 16, 1-2, p. 50-61 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia Infections
  • Chlamydia trachomatis
  • Genetic Markers
  • Infertility
  • Public Health
  18 Citations (Scopus)