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• Article

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)

• Ameliorative effect of caffeic acid against inflammatory pain in rodents

  Mehrotra, A., Shanbhag, R., Chamallamudi, M. R., Singh, V. P. & Mudgal, J., 09-2011, In: European Journal of Pharmacology. 666, 1-3, p. 80-86 7 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Rodentia
  • Pain
  • Analgesics
  • Nitrites
  54 Citations (Scopus)

• Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)

• Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats

  Talwar, S., Nandakumar, K., Nayak, P. G., Bansal, P., Mudgal, J., Mor, V., Rao, C. M. & Lobo, R., 24-03-2011, In: Journal of Ethnopharmacology. 134, 2, p. 323-328 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Terminalia
  • Anti-Inflammatory Agents
  • Freund's Adjuvant
  • Carrageenan
  • Inflammation
  41 Citations (Scopus)

• Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

  Manohara Reddy, S. A., Mudgal, J., Bansal, P., Vasanthraju, S. G., Srinivasan, K. K., Rao, C. M. & Gopalan Kutty, N., 01-01-2011, In: Bioorganic and Medicinal Chemistry. 19, 1, p. 384-392 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quinoxalines
  • Derivatives
  • Antioxidants
  • Anti-Inflammatory Agents
  • Ricinoleic Acids
  22 Citations (Scopus)

• Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

  Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In: Psychopharmacology. 236, 6, p. 1829-1838 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Illness Behavior
  • Cannabinoid Receptors
  • Lipopolysaccharides
  • Oxidative Stress
  • Tumor Necrosis Factor-alpha
  13 Citations (Scopus)

• Catechin, an active constituent of green tea, preserves skeletal muscle activity in dexamethasone induced cachexia by increasing acetylcholine sensitivity in muscles of wistar rats

  Saimithra, T., Kumar, N., Nandakumar, K., Nampoothiri, M. & Rao, C. M., 01-05-2018, In: Indian Journal of Experimental Biology. 56, 5, p. 314-321 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Cachexia
  • Tea
  • Acetylcholine
  • Dexamethasone
  2 Citations (Scopus)

• Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In: Biomedical Reports. 11, 2, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Sprague Dawley Rats
  • Oxidative Stress
  11 Citations (Scopus)

• Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

  Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In: Cytotechnology. p. 1-15 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytotoxicity
  • Catechin
  • Rats
  • Episodic Memory
  • Memory Disorders
  25 Citations (Scopus)

• Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

  Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In: Andrologia. 50, 7, e13037.

  Research output: Contribution to journal › Article › peer-review

  • Wistar Rats
  • Sexual Behavior
  • Spermatozoa
  • Aphrodisiacs
  • Sperm Count
  2 Citations (Scopus)

• Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

  Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In: Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptors
  • Nervous System Diseases
  • Substance P
  • Neurokinin-1 Receptor Antagonists
  • Drug Industry

• Development and validation of a HPLC method for quantification of rivastigmine in rat urine and identification of a novel metabolite in urine by LC-MS/MS

  Arumugam, K., Chamallamudi, M. R., Gilibili, R. R., Mullangi, R., Ganesan, S., Kar, S. S., Averineni, R., Shavi, G. & Udupa, N., 03-2011, In: Biomedical Chromatography. 25, 3, p. 353-361 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivastigmine
  • Metabolites
  • Rats
  • High Pressure Liquid Chromatography
  • Urine
  17 Citations (Scopus)

• Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

  Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In: Pharmacology. 103, 5-6, p. 315-319 5 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Acute Kidney Injury
  • Reperfusion
  • Ischemia
  • Celecoxib
  4 Citations (Scopus)

• Effect of Dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats

  Rao, M. C., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, G. N. & Shenoy, R. R., 09-2011, In: Molecular and Cellular Biochemistry. 355, 1-2, p. 249-256 8 p.

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Rats
  • Curcumin
  • Dexamethasone
  • Wound Healing
  15 Citations (Scopus)

• Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

  Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In: NeuroReport. 28, 9, p. 540-544 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Memory
  • Dementia
  • Insulin
  • Glucose
  12 Citations (Scopus)

• Effect of lecithin on d-galactosamine induced hepatotoxicity through mitochondrial pathway involving Bcl-2 and Bax

  Raj, P. V., Nitesh, K., Prateek, J., Sankhe, M. N., Rao, J. V., Rao, C. M. & Udupa, N., 10-2011, In: Indian Journal of Clinical Biochemistry. 26, 4, p. 378-384 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Galactosamine
  • Lecithins
  • Liver
  • Rats
  • Messenger RNA
  8 Citations (Scopus)

• Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)

• Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model

  Gill, M., Kinra, M., Rai, A., Chamallamudi, M. R. & Kumar, N., 01-01-2018, In: NeuroReport. 29, 2, p. 134-140 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Antidepressive Agents
  • Antioxidants
  • Sucrose
  • Plant Bark
  • Cotyledon
  5 Citations (Scopus)

• Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

  Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon tetrachloride
  • Liver
  • Toxicity
  • Carbon
  • Carbon Tetrachloride
  1 Citation (Scopus)

• Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

  Wankhede, S., Kumar, N., Simon, L., Biswas, S., Gourishetti, K., Ramalingayya, G. V., Joshi, M. & Rao, C. M., 19-10-2017, In: EXCLI Journal. 16, p. 1150-1163 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcones
  • chalcones
  • breast neoplasms
  • Tumor Burden
  • neoplasms
  1 Citation (Scopus)

• Evaluation of novel 3-hydroxyflavone analogues as HDAC inhibitors against colorectal cancer

  Biswas, S., Reddy, N. D., Jayashree, B. S. & Rao, C. M., 01-01-2018, In: Advances in Pharmacological Sciences. 2018, 4751806.

  Research output: Contribution to journal › Article › peer-review

  • 3-hydroxyflavone
  • Histone Deacetylase Inhibitors
  • Histone Deacetylases
  • Colorectal Neoplasms
  • Inhibitory Concentration 50
  4 Citations (Scopus)

• Evaluation of the aphrodisiac potential of a chemically characterized aqueous extract of Tamarindus indica pulp

  Rai, A., Das, S., Chamallamudi, M. R., Nandakumar, K., Shetty, R., Gill, M., Sumalatha, S., Devkar, R., Gourishetti, K. & Kumar, N., 10-01-2018, In: Journal of Ethnopharmacology. 210, p. 118-124 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tamarindus
  • Aphrodisiacs
  • Gas Chromatography-Mass Spectrometry
  • Saponins
  • Phenol
  13 Citations (Scopus)

• Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

  Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In: European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-6
  • Lipopolysaccharides
  • In Vitro Techniques
  • Prostaglandin-Endoperoxide Synthases
  • Reactive Oxygen Species
  1 Citation (Scopus)

• High performance liquid chromatographic fluorescence detection method for the quantification of rivastigmine in rat plasma and brain: Application to preclinical pharmacokinetic studies in rats

  Arumugam, K., Chamallamudi, M. R., Mallayasamy, S. R., Mullangi, R., Ganesan, S., Jamadar, L., Ranjithkumar, A. & Udupa, N., 2011, In: Journal of Young Pharmacists. 3, 4, p. 315-321 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivastigmine
  • Fluorescence
  • Pharmacokinetics
  • ammonium acetate
  • Liquid-Liquid Extraction
  10 Citations (Scopus)

• Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)

• Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

  Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In: Pharmacological Reports. 71, 4, p. 703-712 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Silymarin
  • Liposomes
  • Wistar Rats
  • Alcohols
  • In Vitro Techniques
  1 Citation (Scopus)

• Insulin Combined with Glucose Improves Spatial Learning and Memory in Aluminum Chloride-Induced Dementia in Rats

  Nampoothiri, M., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-01-2017, In: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 36, 2, p. 159-169 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Learning
  • Rats
  • Spatial Memory
  • Dementia
  4 Citations (Scopus)

• Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

  Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 01-08-2018, In: Metabolic Brain Disease. p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Purinergic P1 Receptor Antagonists
  • Cyclooxygenase Inhibitors
  • Haloperidol
  • Antipsychotic Agents
  • Caffeine
  2 Citations (Scopus)

• In vitro and in vivo anticancer studies of 2′-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by hdac inhibition and cell cycle arrest

  Pande, A. N., Biswas, S., Reddy, N. D., Jayashree, B. S., Kumar, N. & Rao, C. M., 03-04-2017, In: EXCLI Journal. 16, p. 448-463 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcone
  • chalcone
  • cell cycle checkpoints
  • colorectal neoplasms
  • Cell Cycle Checkpoints
  14 Citations (Scopus)

• Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

  Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In: International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Chitosan
  • Nanoparticles
  • Calcium
  • Rosuvastatin Calcium
  • Drugs
  19 Citations (Scopus)

• N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

  Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 13-06-2018, In: Toxicology Mechanisms and Methods. p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptor Antagonists
  • Rats
  • Aluminum
  • Spatial Memory
  • Memory Disorders
  7 Citations (Scopus)

• Naringin ameliorates doxorubicin-induced neurotoxicity in vitro and cognitive dysfunction in vivo

  Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Mallik, S. B., Gourishetti, K., Hussain, S. M., Rao, C. M. & Nandakumar, K., 01-04-2018, In: Pharmacognosy Magazine. 14, 55, p. S197-S207

  Research output: Contribution to journal › Article › peer-review

  • naringin
  • Doxorubicin
  • Cognitive Dysfunction
  • naringenin
  • In Vitro Techniques
  2 Citations (Scopus)

• Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats

  Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 27-01-2011, In: Journal of Ethnopharmacology. 133, 2, p. 608-612 5 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Sesamum
  • Wound Healing
  • Dexamethasone
  • Protein-Lysine 6-Oxidase
  36 Citations (Scopus)

• Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

  Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In: Experimental Gerontology. 125, 1 p.

  Research output: Contribution to journal › Article › peer-review

  • N-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-N,N',N',N'',N''-pentaacetic acid
  • Muscle
  • Locomotion
  • Pharmacology
  • Sarcopenia

• Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

  Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In: Inflammopharmacology. 27, 5, p. 941-948 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipopolysaccharides
  • Down-Regulation
  • Illness Behavior
  • Oxidative Stress
  • Anti-Inflammatory Agents
  10 Citations (Scopus)

• Pro-healing effects of morin, a natural antioxidant, on normal and dexamethasone-impaired wounds

  Shenoy, R. R., Sudheendra, A. T., Nayak, P. G., Paul, P., Kutty, N. G. & Rao, C. M., 12-2011, In: Journal of Basic and Clinical Physiology and Pharmacology. 22, 4, p. 131-135 5 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Dexamethasone
  • Antioxidants
  • Wounds and Injuries
  • Granulation Tissue
  1 Citation (Scopus)

• Reversed-Phase HPLC Method for Determination of Temozolomide in Rat Plasma and Brain: Simple, Sensitive and Robust Method

  Attari, Z., Kumar, L., Mallikarjuna Rao, C. & Koteshwara, K. B., 01-06-2018, In: Pharmaceutical Chemistry Journal. 52, 3, p. 266-270 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • High Pressure Liquid Chromatography
  • Brain
  • Pharmaceutical Preparations
  • Temperature

• Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

  Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In: Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylnitrosourea
  • Rutin
  • Rats
  • Doxorubicin
  • Cognitive Dysfunction
  4 Citations (Scopus)

• Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

  Ramalingayya, G. V., Cheruku, S. P., Nayak, P. G., Kishore, A., Shenoy, R., Rao, M. & Krishnadas, N., 29-03-2017, In: Drug Design, Development and Therapy. 11, p. 1011-1026 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutin
  • Memory Disorders
  • Doxorubicin
  • Wistar Rats
  • In Vitro Techniques
  26 Citations (Scopus)

• Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2,1,b]-benzothiazole derivatives

  Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Mallikarjuna Rao, C. & Barve, A., 10-2011, In: Letters in Drug Design and Discovery. 8, 8, p. 717-724 8 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Proton Magnetic Resonance Spectroscopy
  • MCF-7 Cells
  • Inhibitory Concentration 50
  4 Citations (Scopus)

• Synthesis and preliminary in-vitro cytotoxic activity of novel substituted diaryl-imidazo [2, 1, b]-benzothiazole derivatives

  Malik, J. K., Noolvi, M. N., Manvi, F. V., Nanjwade, B. K., Patel, H. M., Manjula, S. N., Rao, M. C. & Barve, A., 11-2011, In: Letters in Drug Design and Discovery. 8, 9, p. 717-724 8 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Proton Magnetic Resonance Spectroscopy
  • MCF-7 Cells
  • Inhibitory Concentration 50

• Temozolomide and its stability—a critical factor

  Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • Drugs
  • drug
  • Degradation
  • Pharmaceutical Preparations
  2 Citations (Scopus)
• Review article

  Epigenetics in cancer: Fundamentals and Beyond

  Biswas, S. & Rao, C. M., 01-05-2017, In: Pharmacology and Therapeutics. 173, p. 118-134 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Neoplasms
  • Carcinogenesis
  • Nucleosomes
  • Gene Targeting
  91 Citations (Scopus)

• Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

  Biswas, S. & Rao, C. M., 15-10-2018, In: European Journal of Pharmacology. 837, p. 8-24 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Protein Domains
  • Neoplasms
  • Enzymes
  • Chromatin
  63 Citations (Scopus)