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• Article

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)

• An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

  Reddy, N. D., Shoja, M. H., Biswas, S., Nayak, P. G., Kumar, N. & Rao, C. M., 25-06-2016, In: Chemico-Biological Interactions. 253, p. 112-124 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Histone Deacetylase Inhibitors
  • Human Activities
  • Cells
  • Derivatives
  16 Citations (Scopus)

• An insight in to the efficacy of dehydrozingerone against aluminium induced cognitive dysfunction in rats

  Anusha, Chamallamudi, M. R., Mudgal, J. & Nampoothiri, M., 01-07-2016, In: International Journal of Pharmaceutical Sciences Review and Research. 39, 1, p. 70-73 4 p., 15.

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Aluminum
  • Cognitive Dysfunction
  • Curcumin
  • Aluminum Chloride
  1 Citation (Scopus)

• Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)

• Antioxidant and antihyperlipidemic activity of Melia azedarach Linn. extracts in rats

  Vijaya Kumar, S., Sanghai, D. B., Mallikarjuna Rao, C. & Shreedhara, C. S., 2013, In: Research Journal of Pharmacy and Technology. 6, 11, p. 1195-1199 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Hypolipidemic Agents
  • ethyl acetate
  • Antioxidants
  • Flavonoids
  2 Citations (Scopus)

• A rat model against chemotherapy plus radiation-induced oral mucositis

  Patel, A., Rajesh, S., Chandrashekhar, V. M., Rathnam, S., Shah, K., Mallikarjuna Rao, C. & Nandakumar, K., 10-2013, In: Saudi Pharmaceutical Journal. 21, 4, p. 399-403 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Stomatitis
  • Radiation
  • Mucositis
  • Drug Therapy
  • Tongue
  3 Citations (Scopus)

• A study on the role of (+)-catechin in suppression of HepG2 proliferation via caspase dependent pathway and enhancement of its in vitro and in vivo cytotoxic potential through liposomal formulation

  Jain, P., Kumar, N., Josyula, V. R., Jagani, H. V., Udupa, N., Mallikarjuna Rao, C. & Vasanth Raj, P., 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 353-365 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Caspases
  • Hep G2 Cells
  • In Vitro Techniques
  • Liposomes
  24 Citations (Scopus)

• Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

  Basu Mallik, S., Mudgal, J., Nampoothiri, M., Hall, S., Dukie, S. A., Grant, G., Rao, C. M. & Arora, D., 06-10-2016, In: Neuroscience Letters. 632, p. 218-223 6 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Lipopolysaccharides
  • Brain
  • Antioxidants
  28 Citations (Scopus)

• Catechin, an active constituent of green tea, preserves skeletal muscle activity in dexamethasone induced cachexia by increasing acetylcholine sensitivity in muscles of wistar rats

  Saimithra, T., Kumar, N., Nandakumar, K., Nampoothiri, M. & Rao, C. M., 01-05-2018, In: Indian Journal of Experimental Biology. 56, 5, p. 314-321 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Cachexia
  • Tea
  • Acetylcholine
  • Dexamethasone
  2 Citations (Scopus)

• Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats

  Cheruku, S. P., Ramalingayya, G. V., Rao, M. C., Biswas, S., Nandakumar, K., Nampoothiri, M., Gourishetti, K. & Kumar, N., 01-02-2018, In: Cytotechnology. p. 1-15 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytotoxicity
  • Catechin
  • Rats
  • Episodic Memory
  • Memory Disorders
  25 Citations (Scopus)

• Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats

  Gill, M., Rai, A., Kinra, M., Sumalatha, S., Rao, C. M., Cheruku, S. P., Devkar, R. & Kumar, N., 01-09-2018, In: Andrologia. 50, 7, e13037.

  Research output: Contribution to journal › Article › peer-review

  • Wistar Rats
  • Sexual Behavior
  • Spermatozoa
  • Aphrodisiacs
  • Sperm Count
  2 Citations (Scopus)

• Effectiveness of clinical pharmacist intervention on health-related quality of life in chronic obstructive pulmonary disorder patients - A randomized controlled study

  Suhaj, A., Manu, M. K., Unnikrishnan, M. K., Vijayanarayana, K. & Mallikarjuna Rao, C., 01-02-2016, In: Journal of Clinical Pharmacy and Therapeutics. 41, 1, p. 78-83 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacists
  • Chronic Obstructive Pulmonary Disease
  • India
  • Quality of Life
  • Lung
  19 Citations (Scopus)

• Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)

• Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model

  Gill, M., Kinra, M., Rai, A., Chamallamudi, M. R. & Kumar, N., 01-01-2018, In: NeuroReport. 29, 2, p. 134-140 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Antidepressive Agents
  • Antioxidants
  • Sucrose
  • Plant Bark
  • Cotyledon
  5 Citations (Scopus)

• Evaluation of novel 3-hydroxyflavone analogues as HDAC inhibitors against colorectal cancer

  Biswas, S., Reddy, N. D., Jayashree, B. S. & Rao, C. M., 01-01-2018, In: Advances in Pharmacological Sciences. 2018, 4751806.

  Research output: Contribution to journal › Article › peer-review

  • 3-hydroxyflavone
  • Histone Deacetylase Inhibitors
  • Histone Deacetylases
  • Colorectal Neoplasms
  • Inhibitory Concentration 50
  4 Citations (Scopus)

• Evaluation of the aphrodisiac potential of a chemically characterized aqueous extract of Tamarindus indica pulp

  Rai, A., Das, S., Chamallamudi, M. R., Nandakumar, K., Shetty, R., Gill, M., Sumalatha, S., Devkar, R., Gourishetti, K. & Kumar, N., 10-01-2018, In: Journal of Ethnopharmacology. 210, p. 118-124 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tamarindus
  • Aphrodisiacs
  • Gas Chromatography-Mass Spectrometry
  • Saponins
  • Phenol
  13 Citations (Scopus)

• Formulation and characterisation of nanosuspensions of BCS class II and IV drugs by combinative method

  Attari, Z., Kalvakuntla, S., Reddy, M. S., Deshpande, M., Rao, C. M. & Koteshwara, K. B., 03-03-2016, In: Journal of Experimental Nanoscience. 11, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Particle size
  • Nanocrystals
  • Ball milling
  • Ibuprofen
  • Solubility
  10 Citations (Scopus)

• Heterocyclic homoprostanoid derivative attenuates monoarthritis in rats: An in vitro and in vivo preclinical paradigm

  Mudgal, J., Manohara Reddy, S. A., Mathew, G., Kishore, A., Mallikarjuna Rao, C. & Nampurath, G. K., 01-01-2018, In: European Journal of Pharmaceutical Sciences. 111, p. 320-329 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-6
  • Lipopolysaccharides
  • In Vitro Techniques
  • Prostaglandin-Endoperoxide Synthases
  • Reactive Oxygen Species
  1 Citation (Scopus)

• Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)

• Impact of caffeic acid on aluminium chloride-induced dementia in rats

  Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In: Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • caffeic acid
  • Dementia
  • Acetylcholinesterase
  • Nitrites
  42 Citations (Scopus)

• Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

  Arora, D., Mudgal, J., Nampoothiri, M., Mallik, S. B., Kinra, M., Hall, S., Anoopkumar-Dukie, S., Grant, G. D. & Rao, C. M., 01-08-2018, In: Metabolic Brain Disease. p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Purinergic P1 Receptor Antagonists
  • Cyclooxygenase Inhibitors
  • Haloperidol
  • Antipsychotic Agents
  • Caffeine
  2 Citations (Scopus)

• In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

  Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In: Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cisplatin
  • Small Interfering RNA
  • In Vitro Techniques
  • Tumors
  • Genes
  14 Citations (Scopus)

• In vitro and in vivo hepatoprotective action of L-α-phosphatidylcholine in alcohol-induced toxicity model

  Raj, P. V., Mudgal, J., Reddy, N. D., Rao, C. M., Bansal, P., Rai, A. & Kumar, N., 01-11-2016, In: International Journal of Pharmaceutical Sciences Review and Research. 41, 1, p. 171-176 6 p., 33.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidylcholines
  • Silymarin
  • Alcohols
  • In Vitro Techniques
  • Sulfhydryl Compounds
  1 Citation (Scopus)

• In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Biswas, S., Srinivasan, K. K. & Rao, C. M., 20-06-2016, In: Journal of Ethnopharmacology. 186, p. 159-168 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Breast Neoplasms
  • Matrix Metalloproteinases
  • In Vitro Techniques
  • Sprague Dawley Rats
  6 Citations (Scopus)

• In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

  Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In: Frontiers in Pharmacology. 7, OCT, 381.

  Research output: Contribution to journal › Article › peer-review

  • N-acetyltalosaminuronic acid
  • p38 Mitogen-Activated Protein Kinases
  • Sucrose
  • Diet
  • Phosphorylation
  2 Citations (Scopus)

• Long circulating PEGylated-chitosan nanoparticles of rosuvastatin calcium: Development and in vitro and in vivo evaluations

  Hirpara, M. R., Manikkath, J., Sivakumar, K., Managuli, R. S., Gourishetti, K., Krishnadas, N., Shenoy, R. R., Jayaprakash, B., Rao, C. M. & Mutalik, S., 01-02-2018, In: International Journal of Biological Macromolecules. 107, p. 2190-2200 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Chitosan
  • Nanoparticles
  • Calcium
  • Rosuvastatin Calcium
  • Drugs
  19 Citations (Scopus)

• Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In: Pharmacological Reports. 65, 3, p. 658-665 8 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Dinitrochlorobenzene
  • Sesamum
  • Sulfasalazine
  • Nitrites
  14 Citations (Scopus)

• N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

  Fernandes, J., Mudgal, J., Rao, C. M., Arora, D., Basu Mallik, S., Pai, K. S. R. & Nampoothiri, M., 13-06-2018, In: Toxicology Mechanisms and Methods. p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptor Antagonists
  • Rats
  • Aluminum
  • Spatial Memory
  • Memory Disorders
  7 Citations (Scopus)

• Naringin ameliorates doxorubicin-induced neurotoxicity in vitro and cognitive dysfunction in vivo

  Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Mallik, S. B., Gourishetti, K., Hussain, S. M., Rao, C. M. & Nandakumar, K., 01-04-2018, In: Pharmacognosy Magazine. 14, 55, p. S197-S207

  Research output: Contribution to journal › Article › peer-review

  • naringin
  • Doxorubicin
  • Cognitive Dysfunction
  • naringenin
  • In Vitro Techniques
  2 Citations (Scopus)

• Naringin and rutin alleviates episodic memory deficits in two differentially challenged object recognition tasks

  Ramalingayya, G. V., Nampoothiri, M., Nayak, P. G., Kishore, A., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 2016, In: Pharmacognosy Magazine. 12, 45, p. S63-S70

  Research output: Contribution to journal › Article › peer-review

  • naringin
  • Rutin
  • Episodic Memory
  • Memory Disorders
  • Recognition (Psychology)
  30 Citations (Scopus)

• Preclinical efficacy of a gastro-sparing novel thiazolidin-4-one in alleviating secondary lesions of polyarthritis: A multi-parametric approach

  Mudgal, J., Gowdra, V. S., Mudgal, P. P., Nayak, P. G., Kumar, N., Attari, Z., Rao, C. M. & Nampurath, G. K., 25-08-2016, In: European Journal of Pharmaceutical Sciences. 91, p. 74-83 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Arthritis
  • Experimental Arthritis
  • Dinoprostone
  • Cytokines
  • Inhibition (Psychology)
  3 Citations (Scopus)

• Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

  Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In: American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • In Vitro Techniques
  • Neoplasms
  • Hexanes
  • Chloroform
  11 Citations (Scopus)

• Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride

  Jetti, R., Raghuveer, C. & Rao, M. C., 2016, In: Toxicology and Industrial Health. 32, 1, p. 183-187 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo biloba
  • Fluorides
  • Memory Disorders
  • Ascorbic Acid
  • Learning
  10 Citations (Scopus)

• Reversed-Phase HPLC Method for Determination of Temozolomide in Rat Plasma and Brain: Simple, Sensitive and Robust Method

  Attari, Z., Kumar, L., Mallikarjuna Rao, C. & Koteshwara, K. B., 01-06-2018, In: Pharmaceutical Chemistry Journal. 52, 3, p. 266-270 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • High Pressure Liquid Chromatography
  • Brain
  • Pharmaceutical Preparations
  • Temperature

• Role of the drug transporter ABCC3 in breast cancer chemoresistance

  Balaji, S. A., Udupa, N., Chamallamudi, M. R., Gupta, V. & Rangarajan, A., 01-05-2016, In: PLoS One. 11, 5, e0155013.

  Research output: Contribution to journal › Article › peer-review

  • breast neoplasms
  • Chemotherapy
  • transporters
  • drugs
  • Breast Neoplasms
  38 Citations (Scopus)

• Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study

  Prasad, V. G., Reddy, N., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, M. C. & Shenoy, R., 07-2016, In: Pharmacognosy Magazine. 12, 47, p. S441-S445

  Research output: Contribution to journal › Article › peer-review

  • hydrazine
  • 1,2-Dimethylhydrazine
  • Colonic Neoplasms
  • Aberrant Crypt Foci
  • Spices
  6 Citations (Scopus)

• Selected novel 5’-amino-2’-hydroxy-1, 3-diaryl-2- propen-1-ones arrest cell cycle of HCT-116 in G₀/G₁ phase

  Simon, L., Srinivasan, K. K., Kumar, N., Reddy, N. D., Biswas, S., Mallikarjuna Rao, C. & Moorkoth, S., 13-01-2016, In: EXCLI Journal. 15, p. 21-32 12 p.

  Research output: Contribution to journal › Article › peer-review

  • cell cycle checkpoints
  • HCT116 Cells
  • Cell Cycle Resting Phase
  • G1 Phase
  • interphase
  4 Citations (Scopus)

• Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

  Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In: Lipids. 48, 6, p. 633-638 6 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamolin
  • sesamol
  • Hyperlipidemias
  • tyloxapol
  • Plasmas
  25 Citations (Scopus)

• Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

  Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In: Andrologia. 48, 10, p. 1236-1243 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aphrodisiacs
  • Wistar Rats
  • Oligospermia
  • Glass
  • Sperm Count
  8 Citations (Scopus)

• Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

  Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In: Cytotechnology. 68, 6, p. 2553-2565 13 p.

  Research output: Contribution to journal › Article › peer-review

  • 1,3,4-oxadiazole
  • Cytotoxicity
  • Amikacin
  • Tumors
  • Cells
  9 Citations (Scopus)

• The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

  Raghu, J., Raghuveer, V. C., Rao, M. C., Somayaji, N. S. & Babu, P. B., 2013, In: Interdisciplinary Toxicology. 6, 4, p. 217-221 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo biloba
  • Fluorides
  • Memory Disorders
  • Ascorbic Acid
  • Learning
  8 Citations (Scopus)

• Validation of a sensitive and robust reversed phase-HPLC method for determination of temozolomide

  Attari, Z., Kumar, L., Rao, C. M. & Koteshwara, K. B., 2016, In: Latin American Journal of Pharmacy. 35, 5, p. 967-971 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • High Pressure Liquid Chromatography
  • formic acid
  • acetonitrile
  • Alkylating Agents
  2 Citations (Scopus)
• Letter

  Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo

  Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 01-09-2016, In: Clinical and Experimental Pharmacology and Physiology. 43, 9, p. 862-863 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)
• Review article

  Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

  Biswas, S. & Rao, C. M., 15-10-2018, In: European Journal of Pharmacology. 837, p. 8-24 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Protein Domains
  • Neoplasms
  • Enzymes
  • Chromatin
  65 Citations (Scopus)