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• Article

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)

• An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

  Reddy, N. D., Shoja, M. H., Biswas, S., Nayak, P. G., Kumar, N. & Rao, C. M., 25-06-2016, In: Chemico-Biological Interactions. 253, p. 112-124 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Histone Deacetylase Inhibitors
  • Human Activities
  • Cells
  • Derivatives
  16 Citations (Scopus)

• An insight in to the efficacy of dehydrozingerone against aluminium induced cognitive dysfunction in rats

  Anusha, Chamallamudi, M. R., Mudgal, J. & Nampoothiri, M., 01-07-2016, In: International Journal of Pharmaceutical Sciences Review and Research. 39, 1, p. 70-73 4 p., 15.

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Aluminum
  • Cognitive Dysfunction
  • Curcumin
  • Aluminum Chloride
  1 Citation (Scopus)

• Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)

• Antioxidant and antihyperlipidemic activity of Melia azedarach Linn. extracts in rats

  Vijaya Kumar, S., Sanghai, D. B., Mallikarjuna Rao, C. & Shreedhara, C. S., 2013, In: Research Journal of Pharmacy and Technology. 6, 11, p. 1195-1199 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Hypolipidemic Agents
  • ethyl acetate
  • Antioxidants
  • Flavonoids
  2 Citations (Scopus)

• A rat model against chemotherapy plus radiation-induced oral mucositis

  Patel, A., Rajesh, S., Chandrashekhar, V. M., Rathnam, S., Shah, K., Mallikarjuna Rao, C. & Nandakumar, K., 10-2013, In: Saudi Pharmaceutical Journal. 21, 4, p. 399-403 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Stomatitis
  • Radiation
  • Mucositis
  • Drug Therapy
  • Tongue
  3 Citations (Scopus)

• A Review on Anticancer Potentials of Benzothiazole Derivatives

  Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In: Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Structure-Activity Relationship
  • Thiazoles
  • Cell Line
  • Neoplasms
  5 Citations (Scopus)

• Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

  Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 01-11-2020, In: Andrologia.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Computer Simulation
  • Sildenafil Citrate
  • Spermatozoa
  • Testis

• A study on the role of (+)-catechin in suppression of HepG2 proliferation via caspase dependent pathway and enhancement of its in vitro and in vivo cytotoxic potential through liposomal formulation

  Jain, P., Kumar, N., Josyula, V. R., Jagani, H. V., Udupa, N., Mallikarjuna Rao, C. & Vasanth Raj, P., 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 353-365 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Caspases
  • Hep G2 Cells
  • In Vitro Techniques
  • Liposomes
  24 Citations (Scopus)

• Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

  Basu Mallik, S., Mudgal, J., Nampoothiri, M., Hall, S., Dukie, S. A., Grant, G., Rao, C. M. & Arora, D., 06-10-2016, In: Neuroscience Letters. 632, p. 218-223 6 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Lipopolysaccharides
  • Brain
  • Antioxidants
  27 Citations (Scopus)

• Cinnamyl Sulfonamide Hydroxamate Derivatives Inhibited LPS-Stimulated NF-kB Expression in RAW 264.7 Cells in In Vitro and Mitigated Experimental Colitis in Wistar Rats in In Vivo

  Joshi, M., Reddy, N. D., Kumara, N., Sumalatha, S. & Rao, C. M., 24-06-2020, In: Current Pharmaceutical Design.

  Research output: Contribution to journal › Article › peer-review

  • RAW 264.7 Cells
  • Sulfonamides
  • NF-kappa B
  • Colitis
  • Lipopolysaccharides

• Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

  Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In: 3 Biotech. 10, 10, 438.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • cognitive disorders
  • glioma
  • Temozolomide
  • Glioma

• Effectiveness of clinical pharmacist intervention on health-related quality of life in chronic obstructive pulmonary disorder patients - A randomized controlled study

  Suhaj, A., Manu, M. K., Unnikrishnan, M. K., Vijayanarayana, K. & Mallikarjuna Rao, C., 01-02-2016, In: Journal of Clinical Pharmacy and Therapeutics. 41, 1, p. 78-83 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacists
  • Chronic Obstructive Pulmonary Disease
  • India
  • Quality of Life
  • Lung
  19 Citations (Scopus)

• Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

  Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2020, In: Journal of Functional Foods. 103638.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Coffee
  • anxiety
  • caffeine
  5 Citations (Scopus)

• Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)

• Evaluation of hepatoprotective effect of a polyherbal megakutki against paracetamol-induced hepatotoxicity

  Elizabeth Giri, A., Rao, V., Singhal, S., Gourishetti, K., Biswas, S., Nandakumar, K., Chamllamudi, M. R., Dave, J., Dave, R., Sumalatha, S. & Kumar, N., 01-10-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 4, p. 1080-1088 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetaminophen
  • Silymarin
  • Inhibitory Concentration 50
  • In Vitro Techniques
  • DNA Fragmentation

• Formulation and characterisation of nanosuspensions of BCS class II and IV drugs by combinative method

  Attari, Z., Kalvakuntla, S., Reddy, M. S., Deshpande, M., Rao, C. M. & Koteshwara, K. B., 03-03-2016, In: Journal of Experimental Nanoscience. 11, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Particle size
  • Nanocrystals
  • Ball milling
  • Ibuprofen
  • Solubility
  10 Citations (Scopus)

• Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)

• Impact of caffeic acid on aluminium chloride-induced dementia in rats

  Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In: Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • caffeic acid
  • Dementia
  • Acetylcholinesterase
  • Nitrites
  42 Citations (Scopus)

• In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

  Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In: Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cisplatin
  • Small Interfering RNA
  • In Vitro Techniques
  • Tumors
  • Genes
  14 Citations (Scopus)

• In vitro and in vivo hepatoprotective action of L-α-phosphatidylcholine in alcohol-induced toxicity model

  Raj, P. V., Mudgal, J., Reddy, N. D., Rao, C. M., Bansal, P., Rai, A. & Kumar, N., 01-11-2016, In: International Journal of Pharmaceutical Sciences Review and Research. 41, 1, p. 171-176 6 p., 33.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidylcholines
  • Silymarin
  • Alcohols
  • In Vitro Techniques
  • Sulfhydryl Compounds
  1 Citation (Scopus)

• In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Biswas, S., Srinivasan, K. K. & Rao, C. M., 20-06-2016, In: Journal of Ethnopharmacology. 186, p. 159-168 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Breast Neoplasms
  • Matrix Metalloproteinases
  • In Vitro Techniques
  • Sprague Dawley Rats
  6 Citations (Scopus)

• In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, akt and p38 MAP kinase in L6 cells

  Mudgal, J., Shetty, P., Reddy, N. D., Akhila, H. S., Gourishetti, K., Mathew, G., Nayak, P. G., Kumar, N., Kishore, A., Kutty, N. G., Nandakumar, K., Shenoy, R. R., Rao, C. M. & Joseph, A., 14-10-2016, In: Frontiers in Pharmacology. 7, OCT, 381.

  Research output: Contribution to journal › Article › peer-review

  • N-acetyltalosaminuronic acid
  • p38 Mitogen-Activated Protein Kinases
  • Sucrose
  • Diet
  • Phosphorylation
  2 Citations (Scopus)

• Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In: Pharmacological Reports. 65, 3, p. 658-665 8 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Dinitrochlorobenzene
  • Sesamum
  • Sulfasalazine
  • Nitrites
  14 Citations (Scopus)

• Naringin and rutin alleviates episodic memory deficits in two differentially challenged object recognition tasks

  Ramalingayya, G. V., Nampoothiri, M., Nayak, P. G., Kishore, A., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 2016, In: Pharmacognosy Magazine. 12, 45, p. S63-S70

  Research output: Contribution to journal › Article › peer-review

  • naringin
  • Rutin
  • Episodic Memory
  • Memory Disorders
  • Recognition (Psychology)
  29 Citations (Scopus)

• Preclinical efficacy of a gastro-sparing novel thiazolidin-4-one in alleviating secondary lesions of polyarthritis: A multi-parametric approach

  Mudgal, J., Gowdra, V. S., Mudgal, P. P., Nayak, P. G., Kumar, N., Attari, Z., Rao, C. M. & Nampurath, G. K., 25-08-2016, In: European Journal of Pharmaceutical Sciences. 91, p. 74-83 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Arthritis
  • Experimental Arthritis
  • Dinoprostone
  • Cytokines
  • Inhibition (Psychology)
  3 Citations (Scopus)

• Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

  Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In: American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • In Vitro Techniques
  • Neoplasms
  • Hexanes
  • Chloroform
  10 Citations (Scopus)

• Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride

  Jetti, R., Raghuveer, C. & Rao, M. C., 2016, In: Toxicology and Industrial Health. 32, 1, p. 183-187 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo biloba
  • Fluorides
  • Memory Disorders
  • Ascorbic Acid
  • Learning
  10 Citations (Scopus)

• Role of the drug transporter ABCC3 in breast cancer chemoresistance

  Balaji, S. A., Udupa, N., Chamallamudi, M. R., Gupta, V. & Rangarajan, A., 01-05-2016, In: PLoS One. 11, 5, e0155013.

  Research output: Contribution to journal › Article › peer-review

  • breast neoplasms
  • Chemotherapy
  • transporters
  • drugs
  • Breast Neoplasms
  37 Citations (Scopus)

• Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

  Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In: European Journal of Medicinal Chemistry. 201, 112335.

  Research output: Contribution to journal › Article › peer-review

  • isocoumarin 3
  • Rosuvastatin Calcium
  • Cells
  • Antineoplastic Agents
  • Ultrasonics

• Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study

  Prasad, V. G., Reddy, N., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, M. C. & Shenoy, R., 07-2016, In: Pharmacognosy Magazine. 12, 47, p. S441-S445

  Research output: Contribution to journal › Article › peer-review

  • hydrazine
  • 1,2-Dimethylhydrazine
  • Colonic Neoplasms
  • Aberrant Crypt Foci
  • Spices
  6 Citations (Scopus)

• Selected novel 5’-amino-2’-hydroxy-1, 3-diaryl-2- propen-1-ones arrest cell cycle of HCT-116 in G₀/G₁ phase

  Simon, L., Srinivasan, K. K., Kumar, N., Reddy, N. D., Biswas, S., Mallikarjuna Rao, C. & Moorkoth, S., 13-01-2016, In: EXCLI Journal. 15, p. 21-32 12 p.

  Research output: Contribution to journal › Article › peer-review

  • cell cycle checkpoints
  • HCT116 Cells
  • Cell Cycle Resting Phase
  • G1 Phase
  • interphase
  4 Citations (Scopus)

• Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

  Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In: 3 Biotech. 10, 4, 149.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • islets of Langerhans
  • Simvastatin
  • Mitochondrial Membrane Potential
  • Insulin-Secreting Cells
  1 Citation (Scopus)

• Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

  Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In: Lipids. 48, 6, p. 633-638 6 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamolin
  • sesamol
  • Hyperlipidemias
  • tyloxapol
  • Plasmas
  25 Citations (Scopus)

• Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

  Das, S., Singhal, S., Kumar, N., Rao, C. M., Sumalatha, S., Dave, J., Dave, R. & Nandakumar, K., 01-12-2016, In: Andrologia. 48, 10, p. 1236-1243 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aphrodisiacs
  • Wistar Rats
  • Oligospermia
  • Glass
  • Sperm Count
  8 Citations (Scopus)

• Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

  Tiwari, A., Gopalan Kutty, N., Kumar, N., Chaudhary, A., Vasanth Raj, P., Shenoy, R. & Mallikarjuna Rao, C., 01-12-2016, In: Cytotechnology. 68, 6, p. 2553-2565 13 p.

  Research output: Contribution to journal › Article › peer-review

  • 1,3,4-oxadiazole
  • Cytotoxicity
  • Amikacin
  • Tumors
  • Cells
  9 Citations (Scopus)

• The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

  Raghu, J., Raghuveer, V. C., Rao, M. C., Somayaji, N. S. & Babu, P. B., 2013, In: Interdisciplinary Toxicology. 6, 4, p. 217-221 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo biloba
  • Fluorides
  • Memory Disorders
  • Ascorbic Acid
  • Learning
  8 Citations (Scopus)

• Validation of a sensitive and robust reversed phase-HPLC method for determination of temozolomide

  Attari, Z., Kumar, L., Rao, C. M. & Koteshwara, K. B., 2016, In: Latin American Journal of Pharmacy. 35, 5, p. 967-971 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • High Pressure Liquid Chromatography
  • formic acid
  • acetonitrile
  • Alkylating Agents
  2 Citations (Scopus)
• Comment/debate

  Corrigendum: Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress (Biomed Rep, (2019) 11, (79-84), 10.3892/br.2019.1226)

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 2020, In: Biomedical Reports. 13, 3, p. 1 1 p., 19.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Catalase
  • Sprague Dawley Rats
• Letter

  Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo

  Ramalingayya, G. V., Nayak, P. G., Shenoy, R. R., Rao, C. M. & Nandakumar, K., 01-09-2016, In: Clinical and Experimental Pharmacology and Physiology. 43, 9, p. 862-863 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)
• Review article

  An appraisal of current pharmacological perspectives of sesamol: A review

  Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In: Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • sesamol
  • Pharmacology
  • Sesamum
  • microbial metalloproteinases
  • Anti-Inflammatory Agents
  1 Citation (Scopus)

• Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

  Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Factors
  • Biological Products
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Drug Compounding
  2 Citations (Scopus)

• Radiotherapy and its impact on the nervous system of cancer survivors

  Kumar, G., Dutta, P., Parihar, V. K., Chamallamudi, M. R. & Kumar, N., 2020, In: CNS and Neurological Disorders - Drug Targets. 19, 5, p. 374-385 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cancer Survivors
  • Nervous System
  • Radiotherapy
  • Cognition
  • Search Engine