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• 2019

  Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

  Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In: Psychopharmacology. 236, 6, p. 1829-1838 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Illness Behavior
  • Cannabinoid Receptors
  • Lipopolysaccharides
  • Oxidative Stress
  • Tumor Necrosis Factor-alpha
  10 Citations (Scopus)

• Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In: Biomedical Reports. 11, 2, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Sprague Dawley Rats
  • Oxidative Stress
  8 Citations (Scopus)

• Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

  Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In: Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptors
  • Nervous System Diseases
  • Substance P
  • Neurokinin-1 Receptor Antagonists
  • Drug Industry

• Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

  Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In: Pharmacology. 103, 5-6, p. 315-319 5 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Acute Kidney Injury
  • Reperfusion
  • Ischemia
  • Celecoxib
  4 Citations (Scopus)

• Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

  Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In: Pharmacological Reports. 71, 4, p. 703-712 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Silymarin
  • Liposomes
  • Wistar Rats
  • Alcohols
  • In Vitro Techniques
  1 Citation (Scopus)

• Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

  Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In: Experimental Gerontology. 125, 1 p.

  Research output: Contribution to journal › Article › peer-review

  • N-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-N,N',N',N'',N''-pentaacetic acid
  • Muscle
  • Locomotion
  • Pharmacology
  • Sarcopenia

• Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

  Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In: Inflammopharmacology. 27, 5, p. 941-948 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipopolysaccharides
  • Down-Regulation
  • Illness Behavior
  • Oxidative Stress
  • Anti-Inflammatory Agents
  9 Citations (Scopus)

• Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

  Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In: Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylnitrosourea
  • Rutin
  • Rats
  • Doxorubicin
  • Cognitive Dysfunction
  3 Citations (Scopus)
• 2017

  Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats

  Nampoothiri, M., Kumar, N., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-05-2017, In: NeuroReport. 28, 9, p. 540-544 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Memory
  • Dementia
  • Insulin
  • Glucose
  12 Citations (Scopus)

• Epigenetics in cancer: Fundamentals and Beyond

  Biswas, S. & Rao, C. M., 01-05-2017, In: Pharmacology and Therapeutics. 173, p. 118-134 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenomics
  • Neoplasms
  • Carcinogenesis
  • Nucleosomes
  • Gene Targeting
  88 Citations (Scopus)

• Evaluation of hepatoprotective effect of aqueous extract of Schrebera swietenioides bark against carbon tetrachloride-induced toxicity in wistar rats

  Kumar, N., Choudhary, A., Tiwari, A., Rasal, A., Jetti, R. & Mallikarjuna Rao, C., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1917-1920 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon tetrachloride
  • Liver
  • Toxicity
  • Carbon
  • Carbon Tetrachloride
  1 Citation (Scopus)

• Evaluation of in vitro and in vivo anticancer potential of two 5-acetamido chalcones against breast cancer

  Wankhede, S., Kumar, N., Simon, L., Biswas, S., Gourishetti, K., Ramalingayya, G. V., Joshi, M. & Rao, C. M., 19-10-2017, In: EXCLI Journal. 16, p. 1150-1163 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcones
  • chalcones
  • breast neoplasms
  • Tumor Burden
  • neoplasms

• Insulin Combined with Glucose Improves Spatial Learning and Memory in Aluminum Chloride-Induced Dementia in Rats

  Nampoothiri, M., Ramalingayya, G. V., Kutty, N. G., Krishnadas, N. & Rao, C. M., 01-01-2017, In: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 36, 2, p. 159-169 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Spatial Learning
  • Rats
  • Spatial Memory
  • Dementia
  4 Citations (Scopus)

• In vitro and in vivo anticancer studies of 2′-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by hdac inhibition and cell cycle arrest

  Pande, A. N., Biswas, S., Reddy, N. D., Jayashree, B. S., Kumar, N. & Rao, C. M., 03-04-2017, In: EXCLI Journal. 16, p. 448-463 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Chalcone
  • chalcone
  • cell cycle checkpoints
  • colorectal neoplasms
  • Cell Cycle Checkpoints
  14 Citations (Scopus)

• Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats

  Ramalingayya, G. V., Cheruku, S. P., Nayak, P. G., Kishore, A., Shenoy, R., Rao, M. & Krishnadas, N., 29-03-2017, In: Drug Design, Development and Therapy. 11, p. 1011-1026 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutin
  • Memory Disorders
  • Doxorubicin
  • Wistar Rats
  • In Vitro Techniques
  26 Citations (Scopus)

• Temozolomide and its stability—a critical factor

  Attari, Z., Rao, C. M., Kumar, L. & Koteshwara, K. B., 01-03-2017, In: Advanced Science Letters. 23, 3, p. 1841-1845 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Temozolomide
  • Drugs
  • drug
  • Degradation
  • Pharmaceutical Preparations
  2 Citations (Scopus)
• 2013

  Antioxidant and antihyperlipidemic activity of Melia azedarach Linn. extracts in rats

  Vijaya Kumar, S., Sanghai, D. B., Mallikarjuna Rao, C. & Shreedhara, C. S., 2013, In: Research Journal of Pharmacy and Technology. 6, 11, p. 1195-1199 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Hypolipidemic Agents
  • ethyl acetate
  • Antioxidants
  • Flavonoids
  2 Citations (Scopus)

• A rat model against chemotherapy plus radiation-induced oral mucositis

  Patel, A., Rajesh, S., Chandrashekhar, V. M., Rathnam, S., Shah, K., Mallikarjuna Rao, C. & Nandakumar, K., 10-2013, In: Saudi Pharmaceutical Journal. 21, 4, p. 399-403 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Stomatitis
  • Radiation
  • Mucositis
  • Drug Therapy
  • Tongue
  3 Citations (Scopus)

• A study on the role of (+)-catechin in suppression of HepG2 proliferation via caspase dependent pathway and enhancement of its in vitro and in vivo cytotoxic potential through liposomal formulation

  Jain, P., Kumar, N., Josyula, V. R., Jagani, H. V., Udupa, N., Mallikarjuna Rao, C. & Vasanth Raj, P., 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 353-365 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Caspases
  • Hep G2 Cells
  • In Vitro Techniques
  • Liposomes
  24 Citations (Scopus)

• Impact of caffeic acid on aluminium chloride-induced dementia in rats

  Khan, K. A., Kumar, N., Nayak, P. G., Nampoothiri, M., Shenoy, R. R., Krishnadas, N., Rao, C. M. & Mudgal, J., 12-2013, In: Journal of Pharmacy and Pharmacology. 65, 12, p. 1745-1752 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • caffeic acid
  • Dementia
  • Acetylcholinesterase
  • Nitrites
  42 Citations (Scopus)

• In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin

  Koganti, S., Jagani, H. V., Palanimuthu, V. R., Mathew, J. A., Rao, M. C. & Rao, J. V., 02-2013, In: Experimental and Molecular Pathology. 94, 1, p. 137-147 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cisplatin
  • Small Interfering RNA
  • In Vitro Techniques
  • Tumors
  • Genes
  14 Citations (Scopus)

• Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Mallikarjuna Rao, C. & Shenoy, R. R., 2013, In: Pharmacological Reports. 65, 3, p. 658-665 8 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Dinitrochlorobenzene
  • Sesamum
  • Sulfasalazine
  • Nitrites
  14 Citations (Scopus)

• Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of xanthium strumarium in transplantable tumors in mice

  Aranjani, J. M., Manuel, A., Mallikarjuna Rao, C., Udupa, N., Rao, J. V., Joy, A. M., Gandhi, P. & Radhakrishnan, E. K., 2013, In: American Journal of Chinese Medicine. 41, 1, p. 145-162 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • In Vitro Techniques
  • Neoplasms
  • Hexanes
  • Chloroform
  10 Citations (Scopus)

• Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia

  Kumar, N., Mudgal, J., Parihar, V. K., Nayak, P. G., Kutty, N. G. & Rao, C. M., 06-2013, In: Lipids. 48, 6, p. 633-638 6 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamolin
  • sesamol
  • Hyperlipidemias
  • tyloxapol
  • Plasmas
  24 Citations (Scopus)

• The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

  Raghu, J., Raghuveer, V. C., Rao, M. C., Somayaji, N. S. & Babu, P. B., 2013, In: Interdisciplinary Toxicology. 6, 4, p. 217-221 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo biloba
  • Fluorides
  • Memory Disorders
  • Ascorbic Acid
  • Learning
  8 Citations (Scopus)
• 2012

  Acute and subacute toxicity of chloroform and hexaneextracts of root of Xanthium strumarium

  Aranjani, J. M., Rao, C. M., Manuel, A., Rao, J. V., Udupa, N. & Hebbar, K., 12-2012, In: Comparative Clinical Pathology. 21, 6, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xanthium
  • Chloroform
  • Hexanes
  • Toxic Plants
  • Mortality
  5 Citations (Scopus)

• Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing mice: A preliminary study

  Pai, K. S. R., Srilatha, P., Suryakant, K., Setty, M. M., Nayak, P. G., Rao, C. M. & Baliga, M. S., 03-2012, In: Pharmaceutical Biology. 50, 3, p. 270-277 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Berberis
  • Ascites
  • Cisplatin
  • Artemia
  • Carcinoma
  11 Citations (Scopus)

• Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway

  Kumar, N., Raj, V. P., Jayshree, B. S., Kar, S. S., Anandam, A., Thomas, S., Jain, P., Rai, A. & Rao, C. M., 08-2012, In: Chemical Biology and Drug Design. 80, 2, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Structure-Activity Relationship
  • Cells
  • Derivatives
  • Assays
  34 Citations (Scopus)

• Histological and physiochemical standardization of Melia azedarach. Linn bark

  Kumar, S. V., Sanghai, D. B., Rao, C. M. & Shreedhara, C. S., 01-2012, In: Asian Pacific Journal of Tropical Biomedicine. 2, 1 SUPPL.

  Research output: Contribution to journal › Article › peer-review

  • Melia azedarach
  • Sieves
  • Phloem
  • Standardization
  • Phytochemicals
  4 Citations (Scopus)