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• An appraisal of current pharmacological perspectives of sesamol: A review

  Bosebabu, B., Cheruku, S. P., Chamallamudi, M. R., Nampoothiri, M., Shenoy, R. R., Nandakumar, K., Parihar, V. K. & Kumar, N., 2020, In: Mini-Reviews in Medicinal Chemistry. 20, 11, p. 988-1000 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • sesamol
  • Pharmacology
  • Sesamum
  • microbial metalloproteinases
  • Anti-Inflammatory Agents
  1 Citation (Scopus)

• A Review on Anticancer Potentials of Benzothiazole Derivatives

  Pathak, N., Rathi, E., Kumar, N., Kini, S. G. & Rao, C. M., 01-01-2020, In: Mini reviews in medicinal chemistry. 20, 1, p. 12-23 12 p.

  Research output: Contribution to journal › Article › peer-review

  • benzothiazole
  • Structure-Activity Relationship
  • Thiazoles
  • Cell Line
  • Neoplasms
  5 Citations (Scopus)

• Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study

  Rai, A., Gill, M., Kinra, M., Dsouza, L. A., Sumalatha, S., Raj, S., Shetty, R., Nandakumar, K., Chamallamudi, M. R. & Kumar, N., 01-11-2020, In: Andrologia.

  Research output: Contribution to journal › Article › peer-review

  • Catechin
  • Computer Simulation
  • Sildenafil Citrate
  • Spermatozoa
  • Testis

• Biologicals to direct nanotherapeutics towards HER2-positive breast cancers

  Kumar, G., Nandakumar, K., Mutalik, S. & Rao, C. M., 07-2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 27, 102197.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Factors
  • Biological Products
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Drug Compounding
  2 Citations (Scopus)

• Cannabinoid receptor 2 activation mitigates lipopolysaccharide-induced neuroinflammation and sickness behavior in mice

  Sahu, P., Mudgal, J., Arora, D., Kinra, M., Mallik, S. B., Rao, C. M., Pai, K. S. R. & Nampoothiri, M., 01-06-2019, In: Psychopharmacology. 236, 6, p. 1829-1838 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Illness Behavior
  • Cannabinoid Receptors
  • Lipopolysaccharides
  • Oxidative Stress
  • Tumor Necrosis Factor-alpha
  13 Citations (Scopus)

• Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 01-01-2019, In: Biomedical Reports. 11, 2, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Sprague Dawley Rats
  • Oxidative Stress
  11 Citations (Scopus)

• Cinnamyl Sulfonamide Hydroxamate Derivatives Inhibited LPS-Stimulated NF-kB Expression in RAW 264.7 Cells in In Vitro and Mitigated Experimental Colitis in Wistar Rats in In Vivo

  Joshi, M., Reddy, N. D., Kumara, N., Sumalatha, S. & Rao, C. M., 24-06-2020, In: Current Pharmaceutical Design.

  Research output: Contribution to journal › Article › peer-review

  • RAW 264.7 Cells
  • Sulfonamides
  • NF-kappa B
  • Colitis
  • Lipopolysaccharides

• Corrigendum: Catechin ameliorates depressive symptoms in sprague dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress (Biomed Rep, (2019) 11, (79-84), 10.3892/br.2019.1226)

  Rai, A., Gill, M., Kinra, M., Shetty, R., Krishnadas, N., Rao, C. M., Sumalatha, S. & Kumar, N., 2020, In: Biomedical Reports. 13, 3, p. 1 1 p., 19.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidative stress
  • Catechin
  • Rats
  • Catalase
  • Sprague Dawley Rats

• Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders

  Eapen, P. M., Rao, C. M. & Nampoothiri, M., 01-04-2019, In: Reviews in the Neurosciences. 30, 3, p. 233-243 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurokinin-1 Receptors
  • Nervous System Diseases
  • Substance P
  • Neurokinin-1 Receptor Antagonists
  • Drug Industry

• Curcumin half analog modulates Interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease

  Kondamudi, P. K., Kovelamudi, H., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2015, In: Pharmacognosy Magazine. 11, 44, p. S296-S302

  Research output: Contribution to journal › Article › peer-review

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • Curcumin
  • Inflammatory Bowel Diseases
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  11 Citations (Scopus)

• Curriculum for pharmacology in pharmacy institutions in India: Opportunities and challenges

  Goyal, R. K., Bhise, S. B., Srinivasan, B. P., Rao, C. M., Sen, T. & Koneri, R., 2014, In: Indian Journal of Pharmacology. 46, 3, p. 241-245 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Molecular Farming
  • Pharmacy
  • Curriculum
  • India
  • Pharmacology
  3 Citations (Scopus)

• Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential

  Pathak, N., Cheruku, S. P., Rao, V., Vibhavari, R. J. A., Sumalatha, S., Gourishetti, K., Rao, C. M. & Kumar, N., 01-10-2020, In: 3 Biotech. 10, 10, 438.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methyl-3-methoxy-4-hydroxystyryl ketone
  • cognitive disorders
  • glioma
  • Temozolomide
  • Glioma

• Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

  Shetty, P. K., Venuvanka, V., Jagani, H. V., Chethan, G. H., Ligade, V. S., Musmade, P. B., Nayak, U. Y., Reddy, M. S., Kalthur, G., Udupa, N., Rao, C. M. & Mutalik, S., 13-10-2015, In: International Journal of Nanomedicine. 10, p. 6477-6491 15 p.

  Research output: Contribution to journal › Article › peer-review

  • morin
  • Sun hoods
  • Radiation protection
  • Antioxidants
  • Radiation Protection
  41 Citations (Scopus)

• Effect of Caffeic Acid on Ischemia-Reperfusion-Induced Acute Renal Failure in Rats

  Kinra, M., Arora, D., Mudgal, J., Pai, K. S. R., Mallikarjuna Rao, C. & Nampoothiri, M., 01-04-2019, In: Pharmacology. 103, 5-6, p. 315-319 5 p.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Acute Kidney Injury
  • Reperfusion
  • Ischemia
  • Celecoxib
  4 Citations (Scopus)

• Effect of coffee constituents, caffeine and caffeic acid on anxiety and lipopolysaccharide-induced sickness behavior in mice

  Mudgal, J., Basu Mallik, S., Nampoothiri, M., Kinra, M., Hall, S., Grant, G. D., Anoopkumar-Dukie, S., Davey, A. K., Rao, C. M. & Arora, D., 01-01-2020, In: Journal of Functional Foods. 103638.

  Research output: Contribution to journal › Article › peer-review

  • caffeic acid
  • Illness Behavior
  • Coffee
  • anxiety
  • caffeine
  6 Citations (Scopus)

• Erratum: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 430734.

  Research output: Contribution to journal › Comment/debate › peer-review
  5 Citations (Scopus)

• Evaluation of hepatoprotective effect of a polyherbal megakutki against paracetamol-induced hepatotoxicity

  Elizabeth Giri, A., Rao, V., Singhal, S., Gourishetti, K., Biswas, S., Nandakumar, K., Chamllamudi, M. R., Dave, J., Dave, R., Sumalatha, S. & Kumar, N., 01-10-2020, In: Indian Journal of Pharmaceutical Education and Research. 54, 4, p. 1080-1088 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acetaminophen
  • Silymarin
  • Inhibitory Concentration 50
  • In Vitro Techniques
  • DNA Fragmentation

• Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells

  Shoja, M. H., Reddy, N. D., Nayak, P. G., Srinivasan, K. K. & Rao, C. M., 20-06-2015, In: Journal of Ethnopharmacology. 168, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rutaceae
  • Cell Cycle Checkpoints
  • Caspase 3
  • Breast Neoplasms
  • lupeol
  20 Citations (Scopus)

• Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer

  Prasad, V. G., Kawade, S., Jayashree, B. S., Reddy, N. D., Francis, A., Nayak, P. G., Kishore, A., Nandakumar, K., Rao, C. M. & Shenoy, R. R., 2014, In: BioMed Research International. 2014, 569130.

  Research output: Contribution to journal › Article › peer-review

  • Dimenhydrinate
  • Aberrant Crypt Foci
  • 1,2-Dimethylhydrazine
  • Colonic Neoplasms
  • N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
  8 Citations (Scopus)

• Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

  Kumar, N., Rai, A., Reddy, N. D., Shenoy, R. R., Mudgal, J., Bansal, P., Mudgal, P. P., Arumugam, K., Udupa, N., Sharma, N. & Rao, C. M., 01-08-2019, In: Pharmacological Reports. 71, 4, p. 703-712 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Silymarin
  • Liposomes
  • Wistar Rats
  • Alcohols
  • In Vitro Techniques
  1 Citation (Scopus)

• Influence of milk components in establishing biofilm mediated bacterial mastitis infections in cattle: A fractional factorial approach

  Atulya, M., Jesil Mathew, A., Venkata Rao, J. & Mallikarjuna Rao, C., 02-2014, In: Research in Veterinary Science. 96, 1, p. 25-27 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Mastitis
  • milk composition
  • biofilm
  • mastitis
  • Biofilms
  11 Citations (Scopus)

• Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

  Nampoothiri, M., Reddy, N. D., John, J., Kumar, N., Kutty Nampurath, G. & Rao Chamallamudi, M., 2014, In: Behavioural Neurology. 2014, 674164.

  Research output: Contribution to journal › Article › peer-review

  • Glutamic Acid
  • Insulin
  • Reactive Oxygen Species
  • Acridine Orange
  • Ethidium
  34 Citations (Scopus)

• Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-Induced inflammatory bowel disorder in albino rats

  Kondamudi, P. K., Kovelamudi, H., Mathew, G., Nayak, P. G., Rao, M. C. & Shenoy, R. R., 2014, In: The Scientific World Journal. 2014, 673248.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Rats
  • Acetic Acid
  • acetic acid
  • Peroxidase
  10 Citations (Scopus)

• In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

  Reddy, N. D., Shoja, M. H., Jayashree, B. S., Nayak, P. G., Kumar, N., Prasad, V. G., Pai, K. S. R. & Rao, C. M., 25-05-2015, In: Chemico-Biological Interactions. 233, p. 81-94 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfonamides
  • Cells
  • Enzyme inhibition
  • Derivatives
  • Colon
  20 Citations (Scopus)

• Modulatory role of simvastatin against aluminium chloride-induced behavioural and biochemical changes in rats

  Nampoothiri, M., John, J., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 2015, In: Behavioural Neurology. 2015, 210169.

  Research output: Contribution to journal › Article › peer-review

  • Aluminum Chloride
  • Simvastatin
  • Aluminum
  • Frontal Lobe
  • Hippocampus
  47 Citations (Scopus)

• Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition

  Azeemuddin, M. M., Rao, C. M., Rafiq, M., Babu, U. V. & Rangesh, P., 01-10-2019, In: Experimental Gerontology. 125, 1 p.

  Research output: Contribution to journal › Article › peer-review

  • N-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-N,N',N',N'',N''-pentaacetic acid
  • Muscle
  • Locomotion
  • Pharmacology
  • Sarcopenia

• Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice

  Mudgal, J., Nampoothiri, M., Basu Mallik, S., Kinra, M., Hall, S., Grant, G., Anoopkumar-Dukie, S., Rao, C. M. & Arora, D., 01-10-2019, In: Inflammopharmacology. 27, 5, p. 941-948 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipopolysaccharides
  • Down-Regulation
  • Illness Behavior
  • Oxidative Stress
  • Anti-Inflammatory Agents
  10 Citations (Scopus)

• Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

  Kumar, N., Dhamija, I., Vasanth Raj, P., Jayashree, B. S., Parihar, V., Manjula, S. N., Thomas, S., Gopalan Kutty, N. & Mallikarjuna Rao, C., 2014, In: Arabian Journal of Chemistry. 7, 4, p. 409-417 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbostyril
  • Tumors
  • Derivatives
  • Liquids
  • Cytotoxicity
  18 Citations (Scopus)

• Radiotherapy and its impact on the nervous system of cancer survivors

  Kumar, G., Dutta, P., Parihar, V. K., Chamallamudi, M. R. & Kumar, N., 2020, In: CNS and Neurological Disorders - Drug Targets. 19, 5, p. 374-385 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cancer Survivors
  • Nervous System
  • Radiotherapy
  • Cognition
  • Search Engine

• Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation

  Mudgal, J., Gowdra, V. S., Mathew, G., Nayak, P. G., Reddy, N. D., Namdeo, N., Kumar, R. R., Kantamaneni, C., Chamallamudi, M. R. & Nampurath, G. K., 05-03-2014, In: Chemico-Biological Interactions. 210, 1, p. 34-42 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Carrageenan
  • Rats
  • Dinoprostone
  • Cytokines
  • Inflammation
  10 Citations (Scopus)

• Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents

  Kumar, J. S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S. D., Hossain, K. A., Reddy, G. S., Edwin, R. K., Joseph, A., Kumar, N., Shenoy, G. G., Rao, C. M. & Pal, M., 01-09-2020, In: European Journal of Medicinal Chemistry. 201, 112335.

  Research output: Contribution to journal › Article › peer-review

  • isocoumarin 3
  • Rosuvastatin Calcium
  • Cells
  • Antineoplastic Agents
  • Ultrasonics

• Rutin protects against doxorubicin-induced cognitive dysfunction while retaining the anticancer potential of dox in a murine model of N-methyl-N-nitrosourea– induced mammary carcinoma

  Ramalingayya, G. V., Gourishetti, K., Nayak, P. G., Mallikarjuna Rao, C., Kishore, A., Alnaseer, S. M., Hussain, S. M. & Nandakumar, K., 01-01-2019, In: Journal of Environmental Pathology, Toxicology and Oncology. 38, 2, p. 153-163 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylnitrosourea
  • Rutin
  • Rats
  • Doxorubicin
  • Cognitive Dysfunction
  4 Citations (Scopus)

• Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

  John, J., Nampoothiri, M., Kumar, N., Mudgal, J., Nampurath, G. K. & Chamallamudi, M. R., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 327-336 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • Aluminum Chloride
  • Lipids
  • Frontal Lobe
  • Hippocampus
  26 Citations (Scopus)

• Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials

  Ghadge, G. A., Gourishetti, K., Chamallamudi, M. R., Nampurath, G. K., Nandakumar, K. & Kumar, N., 01-04-2020, In: 3 Biotech. 10, 4, 149.

  Research output: Contribution to journal › Article › peer-review

  • sesamol
  • islets of Langerhans
  • Simvastatin
  • Mitochondrial Membrane Potential
  • Insulin-Secreting Cells
  1 Citation (Scopus)

• Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

  Kumar, N., Rai, A., Reddy, N. D., Raj, P. V., Jain, P., Deshpande, P., Mathew, G., Kutty, N. G., Udupa, N. & Rao, C. M., 2014, In: Pharmacological Reports. 66, 5, p. 788-798 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Silybin
  • Silymarin
  • Liposomes
  • Biological Availability
  • Hepatocytes
  61 Citations (Scopus)

• Synthesis, characterization, and preclinical evaluation of new thiazolidin-4-ones substituted with p-chlorophenoxy acetic acid and clofibric acid against insulin resistance and metabolic disorder

  Gowdra, V. S., Mudgal, J., Bansal, P., Nayak, P. G., Manohara Reddy, S. A., Shenoy, G. G., Valiathan, M., Chamallamudi, M. R. & Nampurath, G. K., 2014, In: BioMed Research International. 2014, 620434.

  Research output: Contribution to journal › Article › peer-review

  • Clofibric Acid
  • Acetic Acid
  • Insulin Resistance
  • Hypoadiponectinemia
  • Medical problems
  4 Citations (Scopus)

• Targets in anticancer research-a review

  Jayashree, B. S., Nigam, S., Pai, A., Patel, H. K., Reddy, N. D., Kumar, N. & Rao, C. M., 01-08-2015, In: Indian Journal of Experimental Biology. 53, 8, p. 489-507 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmaceutical Preparations
  • Clinical Trials
  • Aromatase
  • Histone Deacetylases
  • Cyclin-Dependent Kinases
  12 Citations (Scopus)

• The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Beeran, A. A., Maliyakkal, N., Rao, C. M. & Udupa, N., 01-04-2015, In: Pharmacognosy Magazine. 11, 42, p. 257-268 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  • Neoplasms
  12 Citations (Scopus)

• The enriched fraction of Vernonia cinerea L. Induces apoptosis and inhibits multi-drug resistance transporters in human epithelial cancer cells

  Appadath Beeran, A., Maliyakkal, N., Rao, C. M. & Udupa, N., 02-12-2014, In: Journal of Ethnopharmacology. PART A, p. 33-42 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vernonia
  • Multiple Drug Resistance
  • Methylene Chloride
  • Epithelial Cells
  • Apoptosis
  7 Citations (Scopus)