A case report of herpetic and candidal esophagitis in an immunocompetent adult

Vishwanath Sathyanarayanan, Abdul Razak, M. Mukhyprana Prabhu, Kavitha Saravu, Pai C. Ganesh, Anuradha K. Rao

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic. A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia, odynophagia and fever. Esophagogastroduodenoscopy (EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm. Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm, multinucleated and faceted nuclei with glassy chromatin, and an occasional Cowdry type A intranuclear inclusion bodies. Few candidal spores were seen in the underlying stroma. Intravenous acyclovir, fluconazole and pantoprazole were initiated. Oral analgesics were given for pain relief. She was treated for a total of 14 days. She showed significant improvement and was tolerating oral intake after discharge. The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.

Original languageEnglish
Pages (from-to)251-252
Number of pages2
JournalAsian Pacific Journal of Tropical Biomedicine
Volume1
Issue number3
DOIs
Publication statusPublished - 01-01-2011

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Digestive System Endoscopy
Intranuclear Inclusion Bodies
Acyclovir
Esophagitis
Fluconazole
Deglutition Disorders
Spores
Esophagus
Ulcer
Chromatin
Analgesics
Cytoplasm
Fever
Epithelium
Epithelial Cells
Recurrence
Pain
pantoprazole

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

Cite this

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abstract = "Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic. A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia, odynophagia and fever. Esophagogastroduodenoscopy (EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm. Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm, multinucleated and faceted nuclei with glassy chromatin, and an occasional Cowdry type A intranuclear inclusion bodies. Few candidal spores were seen in the underlying stroma. Intravenous acyclovir, fluconazole and pantoprazole were initiated. Oral analgesics were given for pain relief. She was treated for a total of 14 days. She showed significant improvement and was tolerating oral intake after discharge. The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.",
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A case report of herpetic and candidal esophagitis in an immunocompetent adult. / Sathyanarayanan, Vishwanath; Razak, Abdul; Prabhu, M. Mukhyprana; Saravu, Kavitha; Ganesh, Pai C.; Rao, Anuradha K.

In: Asian Pacific Journal of Tropical Biomedicine, Vol. 1, No. 3, 01.01.2011, p. 251-252.

Research output: Contribution to journalArticle

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