The aim of present in vitro study was to investigate antimicrobial efficacy of hydroalcoholic extract of Cymbopogon citratus and 2% chlorhexidine gluconate solution against Candida albicans and Enterococcus faecalis. Punch well method using lawn cultures of the C. albicans and E. faecalis was performed to determine the antimicrobial efficacy in the intial stage. The inoculae of these organisms were used to make the lawn culture on Muller Hinton agar plates. Wells were prepared in these lawn cultures and filled with the test agents. The agar plates were kept for incubation at 370 C and zone of inhibition was examined after 24 to 48 hours. Further, Direct Contact method was performed to establish the temporal relation between the pre determined concentration of the extract and the microbicidal efficacy. Gaussian test was employed as test of significance (p<0.05). The results suggest that there was a significant difference in the antimicrobial activity between C. citratus and chlorhexidine gluconate against C. albicans and E. faecalis. C. citratus had a significant antimicrobial efficacy against C. albicans than E. faecalis whereas, chlorhexidine gluconate was more effective against E. faecalis than C. albicans. Clinical Significance: C. Citratus can be used as a potent antifungal agent against C. albicans.
|Title of host publication||Clinical Dentistry Research Compendium|
|Publisher||Nova Science Publishers Inc|
|Number of pages||7|
|Publication status||Published - 01-01-2013|
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