A comparative evaluation of the remineralization potential of three commercially available remineralizing agents on white spot lesions in primary teeth: An in vitro study

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Abstract

Background: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. Aim: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nanohydroxyapatite (nanoHA), casein phosphopeptideamorphous calcium phosphate fluoride (CPPACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth. Settings and Design: This is an in vitro doubleblind randomized study. Materials and Methods: Forty extracted or exfoliated primary teeth were selected and randomized as follows: Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPPACPF, and Group IV: NanoHA. DIAGNOdent readings and scanning electron microscope (SEM) energy dispersive Xray (EDX) analysis were carried out at baseline. The samples were subjected to the test agents after inducing white spot lesions. The readings were repeated postdemineralization and postremineralization. Statistical Analysis: The data were analyzed using IBM SPSS version 20 software with oneway ANOVA, post hoc Tukey's HSD, and paired ttest. Results: SEM evaluation showed favorable surface changes in all the four study groups after remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings showed a highly significant difference between baseline, postdemineralization, and postremineralization values. However, the intergroup comparison was statistically nonsignificant. Conclusion: All test agents were comparable in their remineralization potential.

Original languageEnglish
Pages (from-to)229-237
Number of pages9
JournalJournal of Indian Society of Pedodontics and Preventive Dentistry
Volume35
Issue number3
DOIs
Publication statusPublished - 01-07-2017

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Deciduous Tooth
Dental Caries
Reading
Caseins
Fluorides
X-Rays
Electrons
Dentifrices
Statistical Data Interpretation
Analysis of Variance
Software
In Vitro Techniques
calcium phosphate
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

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title = "A comparative evaluation of the remineralization potential of three commercially available remineralizing agents on white spot lesions in primary teeth: An in vitro study",
abstract = "Background: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. Aim: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nanohydroxyapatite (nanoHA), casein phosphopeptideamorphous calcium phosphate fluoride (CPPACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth. Settings and Design: This is an in vitro doubleblind randomized study. Materials and Methods: Forty extracted or exfoliated primary teeth were selected and randomized as follows: Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPPACPF, and Group IV: NanoHA. DIAGNOdent readings and scanning electron microscope (SEM) energy dispersive Xray (EDX) analysis were carried out at baseline. The samples were subjected to the test agents after inducing white spot lesions. The readings were repeated postdemineralization and postremineralization. Statistical Analysis: The data were analyzed using IBM SPSS version 20 software with oneway ANOVA, post hoc Tukey's HSD, and paired ttest. Results: SEM evaluation showed favorable surface changes in all the four study groups after remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings showed a highly significant difference between baseline, postdemineralization, and postremineralization values. However, the intergroup comparison was statistically nonsignificant. Conclusion: All test agents were comparable in their remineralization potential.",
author = "Pujan Kamath and Rashmi Nayak and Kamath, {Shobha U.} and Deepika Pai",
year = "2017",
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TY - JOUR

T1 - A comparative evaluation of the remineralization potential of three commercially available remineralizing agents on white spot lesions in primary teeth

T2 - An in vitro study

AU - Kamath, Pujan

AU - Nayak, Rashmi

AU - Kamath, Shobha U.

AU - Pai, Deepika

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Background: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. Aim: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nanohydroxyapatite (nanoHA), casein phosphopeptideamorphous calcium phosphate fluoride (CPPACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth. Settings and Design: This is an in vitro doubleblind randomized study. Materials and Methods: Forty extracted or exfoliated primary teeth were selected and randomized as follows: Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPPACPF, and Group IV: NanoHA. DIAGNOdent readings and scanning electron microscope (SEM) energy dispersive Xray (EDX) analysis were carried out at baseline. The samples were subjected to the test agents after inducing white spot lesions. The readings were repeated postdemineralization and postremineralization. Statistical Analysis: The data were analyzed using IBM SPSS version 20 software with oneway ANOVA, post hoc Tukey's HSD, and paired ttest. Results: SEM evaluation showed favorable surface changes in all the four study groups after remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings showed a highly significant difference between baseline, postdemineralization, and postremineralization values. However, the intergroup comparison was statistically nonsignificant. Conclusion: All test agents were comparable in their remineralization potential.

AB - Background: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. Aim: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nanohydroxyapatite (nanoHA), casein phosphopeptideamorphous calcium phosphate fluoride (CPPACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth. Settings and Design: This is an in vitro doubleblind randomized study. Materials and Methods: Forty extracted or exfoliated primary teeth were selected and randomized as follows: Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPPACPF, and Group IV: NanoHA. DIAGNOdent readings and scanning electron microscope (SEM) energy dispersive Xray (EDX) analysis were carried out at baseline. The samples were subjected to the test agents after inducing white spot lesions. The readings were repeated postdemineralization and postremineralization. Statistical Analysis: The data were analyzed using IBM SPSS version 20 software with oneway ANOVA, post hoc Tukey's HSD, and paired ttest. Results: SEM evaluation showed favorable surface changes in all the four study groups after remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings showed a highly significant difference between baseline, postdemineralization, and postremineralization values. However, the intergroup comparison was statistically nonsignificant. Conclusion: All test agents were comparable in their remineralization potential.

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JO - Journal of the Indian Society of Pedodontics and Preventive Dentistry

JF - Journal of the Indian Society of Pedodontics and Preventive Dentistry

SN - 0970-4388

IS - 3

ER -