A critical evaluation and comparison of antimicrobial prophylaxis in elective surgeries across three Hospitals

Yogesh Belagali, M. C. Alwar, Poornachandra Thejeswi, Sheetal D. Ullal, Vani Bhagwath, Shenoy K. Ashok, Mukta Chowta, Sahana D. Acharya

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Objectives: 1. To evaluate and compare the pattern and rationality of prophylactic antimicrobial therapy in elective surgeries. 2. To evaluate and compare the adherence of hospitals to the standard guidelines on prophylactic antimicrobial therapy. Methodology: A total of 150 patients each from a government hospital (group I), medical college teaching hospital (group II), and corporate hospital attached to the institution (group III) who had undergone elective, non-complicated surgery were included. The number & types of antimicrobials used along with duration were noted. Rationality was assessed on the basis of Kunin's criteria, ASHP guidelines & SIGN guidelines. Statistical analysis was done using appropriate tests. Results: Cephalosporins were the most commonly used antimicrobials in all three groups (52.6%,85.7% & 84.8% respectively) followed by nitroimidazoles. Antimicrobial prophylaxis was appropriate in only 14.1%, 23.3% & 32.9% cases in the three groups respectively (p<0.01).The most common problem was prolonged duration of administration in 50.3%,58% & 45% respectively. The implementation of prophylaxis with respect to regimen & duration was erroneous in 20.1%, 12.7% & 4.7% respectively (p<0.01). Conclusion: The rationality & regimen of antimicrobial prophylaxis was comparatively better in the corporate hospital followed by medical college hospital and the government hospital. The present study calls for an urgent review on rational use of antimicrobials for prophylaxis in all the 3 hospitals.

Original languageEnglish
Pages (from-to)1073-1077
Number of pages5
JournalJournal of Clinical and Diagnostic Research
Volume7
Issue number6
DOIs
Publication statusPublished - 17-06-2013

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Surgery
Guidelines
Nitroimidazoles
Cephalosporins
Teaching Hospitals
Statistical methods
Teaching
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Clinical Biochemistry

Cite this

Belagali, Yogesh ; Alwar, M. C. ; Thejeswi, Poornachandra ; Ullal, Sheetal D. ; Bhagwath, Vani ; Ashok, Shenoy K. ; Chowta, Mukta ; Acharya, Sahana D. / A critical evaluation and comparison of antimicrobial prophylaxis in elective surgeries across three Hospitals. In: Journal of Clinical and Diagnostic Research. 2013 ; Vol. 7, No. 6. pp. 1073-1077.
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A critical evaluation and comparison of antimicrobial prophylaxis in elective surgeries across three Hospitals. / Belagali, Yogesh; Alwar, M. C.; Thejeswi, Poornachandra; Ullal, Sheetal D.; Bhagwath, Vani; Ashok, Shenoy K.; Chowta, Mukta; Acharya, Sahana D.

In: Journal of Clinical and Diagnostic Research, Vol. 7, No. 6, 17.06.2013, p. 1073-1077.

Research output: Contribution to journalReview article

TY - JOUR

T1 - A critical evaluation and comparison of antimicrobial prophylaxis in elective surgeries across three Hospitals

AU - Belagali, Yogesh

AU - Alwar, M. C.

AU - Thejeswi, Poornachandra

AU - Ullal, Sheetal D.

AU - Bhagwath, Vani

AU - Ashok, Shenoy K.

AU - Chowta, Mukta

AU - Acharya, Sahana D.

PY - 2013/6/17

Y1 - 2013/6/17

N2 - Objectives: 1. To evaluate and compare the pattern and rationality of prophylactic antimicrobial therapy in elective surgeries. 2. To evaluate and compare the adherence of hospitals to the standard guidelines on prophylactic antimicrobial therapy. Methodology: A total of 150 patients each from a government hospital (group I), medical college teaching hospital (group II), and corporate hospital attached to the institution (group III) who had undergone elective, non-complicated surgery were included. The number & types of antimicrobials used along with duration were noted. Rationality was assessed on the basis of Kunin's criteria, ASHP guidelines & SIGN guidelines. Statistical analysis was done using appropriate tests. Results: Cephalosporins were the most commonly used antimicrobials in all three groups (52.6%,85.7% & 84.8% respectively) followed by nitroimidazoles. Antimicrobial prophylaxis was appropriate in only 14.1%, 23.3% & 32.9% cases in the three groups respectively (p<0.01).The most common problem was prolonged duration of administration in 50.3%,58% & 45% respectively. The implementation of prophylaxis with respect to regimen & duration was erroneous in 20.1%, 12.7% & 4.7% respectively (p<0.01). Conclusion: The rationality & regimen of antimicrobial prophylaxis was comparatively better in the corporate hospital followed by medical college hospital and the government hospital. The present study calls for an urgent review on rational use of antimicrobials for prophylaxis in all the 3 hospitals.

AB - Objectives: 1. To evaluate and compare the pattern and rationality of prophylactic antimicrobial therapy in elective surgeries. 2. To evaluate and compare the adherence of hospitals to the standard guidelines on prophylactic antimicrobial therapy. Methodology: A total of 150 patients each from a government hospital (group I), medical college teaching hospital (group II), and corporate hospital attached to the institution (group III) who had undergone elective, non-complicated surgery were included. The number & types of antimicrobials used along with duration were noted. Rationality was assessed on the basis of Kunin's criteria, ASHP guidelines & SIGN guidelines. Statistical analysis was done using appropriate tests. Results: Cephalosporins were the most commonly used antimicrobials in all three groups (52.6%,85.7% & 84.8% respectively) followed by nitroimidazoles. Antimicrobial prophylaxis was appropriate in only 14.1%, 23.3% & 32.9% cases in the three groups respectively (p<0.01).The most common problem was prolonged duration of administration in 50.3%,58% & 45% respectively. The implementation of prophylaxis with respect to regimen & duration was erroneous in 20.1%, 12.7% & 4.7% respectively (p<0.01). Conclusion: The rationality & regimen of antimicrobial prophylaxis was comparatively better in the corporate hospital followed by medical college hospital and the government hospital. The present study calls for an urgent review on rational use of antimicrobials for prophylaxis in all the 3 hospitals.

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