A fortuitous turn of evidence in an elderly female - A case of pulmonary fusariosis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Pulmonary mycosis is seen infrequently in our country. It is more common in the immunocompromised. The infections caused by less known species like Fusarium have been found to be increasing in incidence in other parts of the world. We hereby report its occurrence in a 79-year-old, non-immunocompromised female who presented with pyrexia of unknown origin. Her ALP and LDH levels were raised. CT scan showed interstitial thickening in subpleural aspect of lungs and multiple enlarged lymph nodes in mediastinum. Liver showed multiple hypodense lesions. Metastasis was suspected for which FNAC of liver was done which showed foci of regenerative hepatocytes with desmoplastic stromal tissue fragments and negative for tumour. Her AFP was normal. The bronchial tree cytology showed endobronchial cells, dust-laden macrophages and chronic inflammatory cells along with fungi on Pap smear studies. This was confirmed by culture that grew Fusarium species. after one week of incubation. The acutely branching septate hyphae of Fusarium species are identical to those of Aspergillus species. In a patient who has a disseminated infection with a septate fungus, growth in culture is important to identify the specific organism and subsequently treatment with appropriate antifungals. In cases like ours, where the infection simulates malignancy, it is even more important to make the correct diagnosis to give the appropriate treatment.

Original languageEnglish
Pages (from-to)ED04-ED05
JournalJournal of Clinical and Diagnostic Research
Volume11
Issue number2
DOIs
Publication statusPublished - 01-02-2017

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Fusariosis
Fusarium
Fungi
Liver
Cytology
Computerized tomography
Macrophages
Aspergillus
Infection
Dust
Papanicolaou Test
Tumors
Lung
Hyphae
Mycoses
Mediastinum
Tissue
Cell Biology
Hepatocytes
Neoplasms

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

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title = "A fortuitous turn of evidence in an elderly female - A case of pulmonary fusariosis",
abstract = "Pulmonary mycosis is seen infrequently in our country. It is more common in the immunocompromised. The infections caused by less known species like Fusarium have been found to be increasing in incidence in other parts of the world. We hereby report its occurrence in a 79-year-old, non-immunocompromised female who presented with pyrexia of unknown origin. Her ALP and LDH levels were raised. CT scan showed interstitial thickening in subpleural aspect of lungs and multiple enlarged lymph nodes in mediastinum. Liver showed multiple hypodense lesions. Metastasis was suspected for which FNAC of liver was done which showed foci of regenerative hepatocytes with desmoplastic stromal tissue fragments and negative for tumour. Her AFP was normal. The bronchial tree cytology showed endobronchial cells, dust-laden macrophages and chronic inflammatory cells along with fungi on Pap smear studies. This was confirmed by culture that grew Fusarium species. after one week of incubation. The acutely branching septate hyphae of Fusarium species are identical to those of Aspergillus species. In a patient who has a disseminated infection with a septate fungus, growth in culture is important to identify the specific organism and subsequently treatment with appropriate antifungals. In cases like ours, where the infection simulates malignancy, it is even more important to make the correct diagnosis to give the appropriate treatment.",
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A fortuitous turn of evidence in an elderly female - A case of pulmonary fusariosis. / Sreeram, Saraswathy; Lobo, Flora Dorothy; Acharya, Vishak; Saralaya, Vishwas.

In: Journal of Clinical and Diagnostic Research, Vol. 11, No. 2, 01.02.2017, p. ED04-ED05.

Research output: Contribution to journalArticle

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