A highly selective “ON-OFF” probe for colorimetric and fluorometric sensing of Cu2+ in water

Barnali Naskar, Ritwik Modak, Dilip K. Maiti, Antonio Bauzá, Antonio Frontera, Pulak Kumar Maiti, Sukhendu Mandal, Sanchita Goswami

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

We present herein a diformyl phenol based probe, 3-({3-[2,3-dihydroxy-propylimino-methyl]-2-hydroxy-5-methyl-benzylidene}-amino)-propane-1,2-diol (H5dpm), as a colorimetric and fluorometric chemosensor for selective detection of Cu2+ in aqueous solution under physiological conditions. This simple system produces a colorimetric change enabling naked eye detection as well as on-off fluorescence response towards Cu2+ in an aqueous medium with a detection limit of 11.2 nM. To further demonstrate the utility of H5dpm, we next explored the application of H5dpm for imaging Cu2+ in Vero cells. The attractive imaging properties of the H5dpm probe will open up avenues for molecular imaging and biomedical applications.

Original languageEnglish
Pages (from-to)11312-11321
Number of pages10
JournalRSC Advances
Volume7
Issue number19
DOIs
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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